AU2014346695B2 - Assays for IGFBP7 having improved performance in biological samples - Google Patents

Assays for IGFBP7 having improved performance in biological samples Download PDF

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Publication number
AU2014346695B2
AU2014346695B2 AU2014346695A AU2014346695A AU2014346695B2 AU 2014346695 B2 AU2014346695 B2 AU 2014346695B2 AU 2014346695 A AU2014346695 A AU 2014346695A AU 2014346695 A AU2014346695 A AU 2014346695A AU 2014346695 B2 AU2014346695 B2 AU 2014346695B2
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antibody
seq
amino acid
acid sequence
human
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AU2014346695A
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AU2014346695A1 (en
Inventor
Srivatsa Venkatasubbarao
Ravi A. Vijayendran
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Astute Medical Inc
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Astute Medical Inc
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54306—Solid-phase reaction mechanisms
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/558—Immunoassay; Biospecific binding assay; Materials therefor using diffusion or migration of antigen or antibody
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/74—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving hormones or other non-cytokine intercellular protein regulatory factors such as growth factors, including receptors to hormones and growth factors
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/10—Immunoglobulins specific features characterized by their source of isolation or production
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/46—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans from vertebrates
    • G01N2333/47—Assays involving proteins of known structure or function as defined in the subgroups
    • G01N2333/4701—Details
    • G01N2333/4745—Insulin-like growth factor binding protein
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/34—Genitourinary disorders
    • G01N2800/347—Renal failures; Glomerular diseases; Tubulointerstitial diseases, e.g. nephritic syndrome, glomerulonephritis; Renovascular diseases, e.g. renal artery occlusion, nephropathy

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biotechnology (AREA)
  • Cell Biology (AREA)
  • General Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Food Science & Technology (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Endocrinology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
AU2014346695A 2013-11-06 2014-11-06 Assays for IGFBP7 having improved performance in biological samples Active AU2014346695B2 (en)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US201361900942P 2013-11-06 2013-11-06
US61/900,942 2013-11-06
US201462054324P 2014-09-23 2014-09-23
US62/054,324 2014-09-23
US201462064380P 2014-10-15 2014-10-15
US62/064,380 2014-10-15
PCT/US2014/064327 WO2015069880A1 (en) 2013-11-06 2014-11-06 Assays for igfbp7 having improved performance in biological samples

Publications (2)

Publication Number Publication Date
AU2014346695A1 AU2014346695A1 (en) 2016-06-16
AU2014346695B2 true AU2014346695B2 (en) 2020-10-15

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Family Applications (1)

Application Number Title Priority Date Filing Date
AU2014346695A Active AU2014346695B2 (en) 2013-11-06 2014-11-06 Assays for IGFBP7 having improved performance in biological samples

Country Status (12)

Country Link
US (3) US9822172B2 (cg-RX-API-DMAC7.html)
EP (2) EP3556863B1 (cg-RX-API-DMAC7.html)
JP (4) JP2017501211A (cg-RX-API-DMAC7.html)
KR (1) KR102404285B1 (cg-RX-API-DMAC7.html)
CN (1) CN105793439B (cg-RX-API-DMAC7.html)
AU (1) AU2014346695B2 (cg-RX-API-DMAC7.html)
BR (1) BR112016010106A2 (cg-RX-API-DMAC7.html)
CA (2) CA2929547C (cg-RX-API-DMAC7.html)
EA (1) EA201690731A1 (cg-RX-API-DMAC7.html)
HK (1) HK1221490A1 (cg-RX-API-DMAC7.html)
MX (1) MX375701B (cg-RX-API-DMAC7.html)
WO (1) WO2015069880A1 (cg-RX-API-DMAC7.html)

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AU2011269775B2 (en) 2010-06-23 2015-01-15 Astute Medical, Inc. Methods and compositions for diagnosis and prognosis of renal injury and renal failure
EP3540440B1 (en) 2011-12-08 2022-09-28 Astute Medical, Inc. Methods and uses for evaluating renal injury and renal status
JP6681195B2 (ja) 2013-01-17 2020-04-15 アスチュート メディカル，インコーポレイテッド 腎損傷および腎不全の診断および予後診断のための方法ならびに組成物
WO2015084939A1 (en) 2013-12-03 2015-06-11 Astute Medical, Inc. Methods and compositions for diagnosis and prognosis of renal injury and renal failure
WO2016164854A1 (en) 2015-04-09 2016-10-13 Astute Medical, Inc. Methods and compositions for diagnosis and prognosis of renal injury and renal failure
WO2017060525A1 (en) * 2015-10-08 2017-04-13 Roche Diagnostics Gmbh Igfbp7 for prediction of risk of aki when measured prior to surgery
EP3465201A4 (en) 2016-06-06 2020-08-26 Astute Medical, Inc. MANAGEMENT OF ACUTE KIDNEY DAMAGE USING INSULINOMIMETIC GROWTH FACTOR BINDING PROTEIN 7 AND TISSUE METALLOPROTEINASE 2 INHIBITOR
US11346846B2 (en) 2017-02-06 2022-05-31 Astute Medical, Inc. Methods and compositions for diagnosis and prognosis of renal injury and renal failure
WO2018187453A1 (en) 2017-04-05 2018-10-11 Astute Medical, Inc. Assays for timp2 having improved performance in biological samples
US11435364B2 (en) 2018-05-24 2022-09-06 Renibus Therapeutics, Inc. Methods of treating patients at risk for renal injury and renal failure
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KR102533791B1 (ko) * 2022-09-15 2023-05-18 경북대학교 산학협력단 비색법 신호형질 복합체, 이를 이용하는 신장질환 진단용 키트 및 진단법

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Also Published As

Publication number Publication date
JP2017501211A (ja) 2017-01-12
US20160289308A1 (en) 2016-10-06
HK1221490A1 (zh) 2017-06-02
CA2929547C (en) 2023-02-28
MX375701B (es) 2025-03-06
CA2929547A1 (en) 2015-05-14
EA201690731A1 (ru) 2016-10-31
CA3185700A1 (en) 2015-05-14
KR20160068988A (ko) 2016-06-15
US10562961B2 (en) 2020-02-18
AU2014346695A1 (en) 2016-06-16
BR112016010106A2 (pt) 2017-12-05
US20200247879A1 (en) 2020-08-06
CN105793439B (zh) 2020-09-04
JP2022068143A (ja) 2022-05-09
EP3066221A1 (en) 2016-09-14
US20180066045A1 (en) 2018-03-08
KR102404285B1 (ko) 2022-05-31
EP3556863A1 (en) 2019-10-23
EP3556863B1 (en) 2024-09-18
JP2023052239A (ja) 2023-04-11
US9822172B2 (en) 2017-11-21
MX2016005834A (es) 2016-11-17
EP3066221A4 (en) 2017-09-20
WO2015069880A1 (en) 2015-05-14
JP7277623B2 (ja) 2023-05-19
CN105793439A (zh) 2016-07-20
JP2020048569A (ja) 2020-04-02

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