AU2014342180B2 - Method for scalable skeletal muscle lineage specification and cultivation - Google Patents

Method for scalable skeletal muscle lineage specification and cultivation Download PDF

Info

Publication number
AU2014342180B2
AU2014342180B2 AU2014342180A AU2014342180A AU2014342180B2 AU 2014342180 B2 AU2014342180 B2 AU 2014342180B2 AU 2014342180 A AU2014342180 A AU 2014342180A AU 2014342180 A AU2014342180 A AU 2014342180A AU 2014342180 B2 AU2014342180 B2 AU 2014342180B2
Authority
AU
Australia
Prior art keywords
cell line
self
myogenic
differentiation
cell
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
AU2014342180A
Other languages
English (en)
Other versions
AU2014342180A1 (en
Inventor
Nicholas J. Genovese
R. Michael Roberts
Bhanu Prakash V. L. Telugu
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Upside Foods Inc
University of Missouri St Louis
Original Assignee
Upside Foods Inc
University of Missouri Columbia
University of Missouri St Louis
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=53005145&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=AU2014342180(B2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Upside Foods Inc, University of Missouri Columbia, University of Missouri St Louis filed Critical Upside Foods Inc
Publication of AU2014342180A1 publication Critical patent/AU2014342180A1/en
Application granted granted Critical
Publication of AU2014342180B2 publication Critical patent/AU2014342180B2/en
Priority to AU2019202244A priority Critical patent/AU2019202244B2/en
Assigned to THE CURATORS OF THE UNIVERSITY OF MISSOURI, UPSIDE FOODS, INC. reassignment THE CURATORS OF THE UNIVERSITY OF MISSOURI Request to Amend Deed and Register Assignors: MEMPHIS MEATS, INC., THE CURATORS OF THE UNIVERSITY OF MISSOURI
Ceased legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06Animal cells or tissues; Human cells or tissues
    • C12N5/0602Vertebrate cells
    • C12N5/0652Cells of skeletal and connective tissues; Mesenchyme
    • C12N5/0658Skeletal muscle cells, e.g. myocytes, myotubes, myoblasts
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L13/00Meat products; Meat meal; Preparation or treatment thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/28Bone marrow; Haematopoietic stem cells; Mesenchymal stem cells of any origin, e.g. adipose-derived stem cells
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/48Reproductive organs
    • A61K35/54Ovaries; Ova; Ovules; Embryos; Foetal cells; Germ cells
    • A61K35/545Embryonic stem cells; Pluripotent stem cells; Induced pluripotent stem cells; Uncharacterised stem cells
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/10Cells modified by introduction of foreign genetic material
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23VINDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2002/00Food compositions, function of food ingredients or processes for food or foodstuffs
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00Active agents used in cell culture processes, e.g. differentation
    • C12N2501/30Hormones
    • C12N2501/38Hormones with nuclear receptors
    • C12N2501/39Steroid hormones
    • C12N2501/392Sexual steroids
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00Active agents used in cell culture processes, e.g. differentation
    • C12N2501/40Regulators of development
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00Active agents used in cell culture processes, e.g. differentation
    • C12N2501/40Regulators of development
    • C12N2501/415Wnt; Frizzeled
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00Active agents used in cell culture processes, e.g. differentation
    • C12N2501/60Transcription factors
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00Active agents used in cell culture processes, e.g. differentation
    • C12N2501/60Transcription factors
    • C12N2501/602Sox-2
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00Active agents used in cell culture processes, e.g. differentation
    • C12N2501/60Transcription factors
    • C12N2501/603Oct-3/4
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00Active agents used in cell culture processes, e.g. differentation
    • C12N2501/60Transcription factors
    • C12N2501/604Klf-4
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00Active agents used in cell culture processes, e.g. differentation
    • C12N2501/70Enzymes
    • C12N2501/72Transferases [EC 2.]
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00Active agents used in cell culture processes, e.g. differentation
    • C12N2501/70Enzymes
    • C12N2501/72Transferases [EC 2.]
    • C12N2501/727Kinases (EC 2.7.)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00Active agents used in cell culture processes, e.g. differentation
    • C12N2501/999Small molecules not provided for elsewhere
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2506/00Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells
    • C12N2506/02Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells from embryonic cells
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2506/00Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells
    • C12N2506/45Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells from artificially induced pluripotent stem cells

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • Cell Biology (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Developmental Biology & Embryology (AREA)
  • Rheumatology (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Virology (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Reproductive Health (AREA)
  • Nutrition Science (AREA)
  • Food Science & Technology (AREA)
  • Polymers & Plastics (AREA)
  • Gynecology & Obstetrics (AREA)
  • Hematology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Fodder In General (AREA)
AU2014342180A 2013-10-30 2014-10-30 Method for scalable skeletal muscle lineage specification and cultivation Ceased AU2014342180B2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2019202244A AU2019202244B2 (en) 2013-10-30 2019-04-02 Method for scalable skeletal muscle lineage specification and cultivation

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201361962068P 2013-10-30 2013-10-30
US61/962,068 2013-10-30
PCT/US2014/063250 WO2015066377A1 (en) 2013-10-30 2014-10-30 Method for scalable skeletal muscle lineage specification and cultivation

Related Child Applications (1)

Application Number Title Priority Date Filing Date
AU2019202244A Division AU2019202244B2 (en) 2013-10-30 2019-04-02 Method for scalable skeletal muscle lineage specification and cultivation

Publications (2)

Publication Number Publication Date
AU2014342180A1 AU2014342180A1 (en) 2016-05-19
AU2014342180B2 true AU2014342180B2 (en) 2019-01-03

Family

ID=53005145

Family Applications (2)

Application Number Title Priority Date Filing Date
AU2014342180A Ceased AU2014342180B2 (en) 2013-10-30 2014-10-30 Method for scalable skeletal muscle lineage specification and cultivation
AU2019202244A Ceased AU2019202244B2 (en) 2013-10-30 2019-04-02 Method for scalable skeletal muscle lineage specification and cultivation

Family Applications After (1)

Application Number Title Priority Date Filing Date
AU2019202244A Ceased AU2019202244B2 (en) 2013-10-30 2019-04-02 Method for scalable skeletal muscle lineage specification and cultivation

Country Status (10)

Country Link
US (3) US20160251625A1 (cg-RX-API-DMAC7.html)
EP (1) EP3071040B2 (cg-RX-API-DMAC7.html)
JP (2) JP6728049B2 (cg-RX-API-DMAC7.html)
CN (2) CN111154726A (cg-RX-API-DMAC7.html)
AU (2) AU2014342180B2 (cg-RX-API-DMAC7.html)
BR (1) BR112016009803B1 (cg-RX-API-DMAC7.html)
CA (1) CA2928726A1 (cg-RX-API-DMAC7.html)
ES (1) ES2782380T5 (cg-RX-API-DMAC7.html)
IL (2) IL296889A (cg-RX-API-DMAC7.html)
WO (1) WO2015066377A1 (cg-RX-API-DMAC7.html)

Families Citing this family (39)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111154726A (zh) 2013-10-30 2020-05-15 密苏里大学的策展人 可扩展性骨骼肌谱系特化和培育的方法
US11318167B2 (en) 2015-12-11 2022-05-03 The Johns Hopkins University Isolation of fusion-competent myoblasts and therapeutic applications thereof related to muscular dystrophy
AU2017208094A1 (en) * 2016-01-14 2018-08-09 Upside Foods, Inc. Methods for extending the replicative capacity of somatic cells during an ex vivo cultivation process
IL302693B2 (en) 2016-07-11 2025-10-01 Yissum Res Dev Co Of Hebrew Univ Jerusalem Ltd Methods and systems for growing cells in culture
EP4424837A3 (en) 2017-05-06 2024-12-11 Upside Foods, Inc. Compositions and methods for increasing the culture density of a cellular biomass within a cultivation infrastructure
EP3634152A1 (en) * 2017-06-07 2020-04-15 Wild Type, Inc. Ex vivo meat production
EP3638777A4 (en) 2017-07-13 2021-05-12 Memphis Meats, Inc. COMPOSITIONS AND METHODS FOR INCREASING THE EFFICIENCY OF CELL CULTURES FOR FOOD MANUFACTURING
EP3728560A4 (en) 2017-07-15 2021-04-14 Aleph Farms Ltd. COMPOSITION OF CULTIVATED MEAT
GB2573327B (en) * 2018-05-03 2021-05-12 Mosa Meat Bv Apparatus and process for production of tissue from cells
US12478571B2 (en) 2018-12-17 2025-11-25 Pontis Biologics, Inc. Enzyme based compositions and methods for removing dental calculi
WO2020230138A1 (en) 2019-05-14 2020-11-19 Aleph Farms Ltd. Pluripotent cell aggregates and use thereof
CA3210518C (en) 2019-05-28 2024-03-26 Upside Foods, Inc. Methods for preparing a comestible meat product
MX2022006095A (es) 2019-11-20 2022-08-16 Upside Foods Inc Aparatos y sistemas para preparar un producto carnico.
CA3163651A1 (en) 2019-12-02 2021-06-10 Avant Meats Company Limited Methods of meat production by in vitro cell cultivation
US20210235733A1 (en) 2020-02-04 2021-08-05 Memphis Meats, Inc. Characteristics of meat products
EP4162026A1 (en) 2020-06-05 2023-04-12 Upside Foods, Inc. Nutrient media for the production of slaughter-free meat
GB202008821D0 (en) * 2020-06-10 2020-07-22 Highersteaks Ltd Systems and methods for cell conversion
US12252681B2 (en) 2020-08-18 2025-03-18 Upside Foods, Inc. Systems, devices, and methods for sterilizing bioreactors and culture media
US20220195368A1 (en) * 2020-12-21 2022-06-23 Upside Foods, Inc. Fluid conduit with radial expansion of fluid flow
US11912967B2 (en) 2020-12-22 2024-02-27 Upside Foods, Inc. Systems and methods for cultivating tissue on porous substrates
WO2022156939A1 (en) * 2021-01-22 2022-07-28 HigherSteaks Limited Products for cell conversion
EP4304376A4 (en) 2021-03-10 2025-03-19 Terasaki Institute For Biomedical Innovation PROCESSES AND SYSTEMS FOR THE PRODUCTION OF PRODUCTS SUCH AS PRODUCTS OF ANIMAL ORIGIN
US20220333081A1 (en) 2021-04-07 2022-10-20 Upside Foods, Inc. Generation of cell-based products for consumption that comprise proteins from exotic, endangered, and extinct species
IL317525A (en) 2021-04-28 2025-02-01 Upside Foods Inc Creating cell-based products for human consumption
CA3216903A1 (en) 2021-05-06 2022-11-10 Yeda Research And Development Co. Ltd. Method for inducing hypertrophic muscle fibers for industrial meat production
US20250092358A1 (en) * 2021-05-28 2025-03-20 Abs Global, Inc. In Vitro Breeding Systems and Methods in Livestock
JP2024523133A (ja) 2021-06-11 2024-06-28 アップサイド フーズ, インコーポレイテッド 乾燥細胞粉末を含む細胞ベースの肉製品、及びそのような製品の製造方法
WO2022265632A1 (en) 2021-06-16 2022-12-22 Upside Foods, Inc. Plant fat-based scaffolds for the growth of cell-based meats and methods of making such products
US20240327794A1 (en) 2021-07-09 2024-10-03 Suprême Foodstuffs comprising cells differentiated from engineered oligopotent stem cells
EP4418874A4 (en) 2021-10-19 2025-09-24 Eat Scifi Inc PLANT/ANIMAL CELL BASED HYBRID MEAT SUBSTITUTE
CN118541474A (zh) * 2021-12-23 2024-08-23 阿普赛德食品股份有限公司 放大肌原性组织:晚期传代肌原性
EP4292440A1 (en) 2022-06-14 2023-12-20 Upside Foods, Inc. Suspension based chicken product formulation
EP4293109A1 (en) 2022-06-14 2023-12-20 Upside Foods, Inc. Non-skeletal muscle-derived cells as a source of suspension capable myogenic cells for cultured foods
US11981884B2 (en) 2022-10-17 2024-05-14 Upside Foods, Inc. Pipe-based bioreactors for producing comestible meat products and methods of using the same
WO2025011578A1 (zh) * 2023-07-10 2025-01-16 中国农业大学 一种猪多能干细胞的肌源性分化方法及其用于细胞培养肉制备
EP4497814A1 (de) 2023-07-28 2025-01-29 Green Elephant Biotech GmbH Vorrichtung zur vermehrung von differenzierten und undifferenzierten zellen und verwendung der vorrichtung für die herstellung von kultivierten lebensmitteln
WO2025049891A1 (en) 2023-09-01 2025-03-06 Upside Foods, Inc. Transposon system and methods of using the same
US20250120418A1 (en) * 2023-10-12 2025-04-17 Btl Healthcare Technologies A.S. Pet food, methods and devices for producing pet food
WO2025141211A1 (en) * 2023-12-29 2025-07-03 Meatable B.V. Cells for forward programming

Family Cites Families (38)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5510254A (en) 1986-04-18 1996-04-23 Advanced Tissue Sciences, Inc. Three dimensional cell and tissue culture system
AU642184B2 (en) * 1989-12-21 1993-10-14 University Of Georgia Research Foundation, Inc., The Bovine myogenic factor gene
US5298422A (en) * 1991-11-06 1994-03-29 Baylor College Of Medicine Myogenic vector systems
WO1999031222A1 (en) 1997-12-18 1999-06-24 Willem Frederik Van Eelen Industrial scale production of meat from in vitro cell cultures
US6444229B2 (en) 1998-02-27 2002-09-03 Purdue Research Foundation Submucosa gel compositions
US6537782B1 (en) 1998-06-01 2003-03-25 Chugai Seiyaku Kabushiki Kaisha Media for culturing animal cells and process for producing protein by using the same
US6835390B1 (en) 2000-11-17 2004-12-28 Jon Vein Method for producing tissue engineered meat for consumption
EP1639097B1 (en) * 2003-06-25 2013-08-07 Ottawa Health Research Institute Methods and compositions for modulating stem cell growth and differentiation
DE102004017484B4 (de) 2004-04-08 2006-07-06 Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. Verfahren zur Herstellung einer biologischen Materialzusammensetzung tierischen Ursprungs
US20060121006A1 (en) 2004-09-10 2006-06-08 Chancellor Michael B Production of nutritional and therapeutic products from cultured animal cells
CA2580433A1 (en) 2004-09-17 2006-04-20 Jon Vein Tissue engineered meat for consumption and a method for producing tissue engineered meat for consumption
EP1956923A1 (en) * 2005-11-02 2008-08-20 Nestec S.A. Isoflavone compositions for reducing accumulation of body fat in male mammals, and methods for their use
US20110191871A1 (en) * 2006-02-28 2011-08-04 Trustees Of Boston University Methods to identify factors associated with muscle growth and uses thereof
DE102007029699B4 (de) 2007-06-27 2010-12-02 Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. Isolierte proliferierende Zellen mit Stammzelleigenschaften aus adultem Gewebe von wechselwarmen Wirbeltieren, stabile Zellkulturen davon und Verfahren zu deren Herstellung
CN101624570B (zh) 2008-07-07 2011-04-13 刘志军 中药培养养殖肉灵芝方法及养殖肉灵芝保健品的制备方法
US20110301249A1 (en) 2008-12-12 2011-12-08 Kedar Challakere Stem cell enhanced protein products and uses therof
US20110091604A1 (en) 2009-10-21 2011-04-21 Seth Adrian Miller Synthetic meat
WO2012034101A2 (en) 2010-09-09 2012-03-15 The Regents Of The University Of California Expandable cell source of neuronal stem cell populations and methods for obtaining and using them
WO2012170995A2 (en) * 2011-06-10 2012-12-13 University Of Georgia Research Foundation, Inc. Avian induced pluripotent stem cells and their use
US8900572B2 (en) 2011-06-14 2014-12-02 UNIVERSITé LAVAL Myogenic differentiation of stem cells and uses thereof
US8883503B2 (en) 2011-06-23 2014-11-11 Indian Institute Of Technology Kanpur Hydrogel scaffolds for tissue engineering
US10039306B2 (en) 2012-03-16 2018-08-07 Impossible Foods Inc. Methods and compositions for consumables
CN112471322A (zh) 2011-07-12 2021-03-12 非凡食品有限公司 用于消费品的方法和组合物
CA2842837A1 (en) 2011-07-26 2013-01-31 The Curators Of The University Of Missouri Engineered comestible meat
CA2792081C (en) * 2011-10-11 2020-10-27 Bond University Ltd Layered compositions comprising 3d nanofibre webbing for tissue repair
WO2013073246A1 (en) * 2011-11-18 2013-05-23 Kyoto University Method of inducing differentiation from pluripotent stem cells to skeletal muscle cells
CN104620104B (zh) 2012-03-16 2017-03-01 非凡食品有限公司 用于蛋白质纯化的亲和试剂
EP2831291B1 (en) 2012-03-28 2019-04-24 Modern Meadow, Inc. Engineered leather and methods of manufacture thereof
EP2943077B1 (en) 2013-01-11 2018-10-31 Impossible Foods Inc. Non-dairy ricotta cheese replica
ES3047667T3 (en) 2013-02-22 2025-12-04 Univ Leland Stanford Junior Methods relating to telomere extension
WO2015038988A1 (en) 2013-09-13 2015-03-19 Modern Meadow, Inc. Edible and animal-product-free microcarriers for engineered meat
CN111154726A (zh) 2013-10-30 2020-05-15 密苏里大学的策展人 可扩展性骨骼肌谱系特化和培育的方法
US20150296834A1 (en) 2014-04-17 2015-10-22 Savage River, Inc. dba Beyond Meat, Inc. Plant based meat structured protein products
US9526267B2 (en) 2014-04-17 2016-12-27 Savage River, Inc. Nutrient-dense meat structured protein products
MX2018000941A (es) 2015-07-24 2019-08-29 Synthetic Genomics Inc Ingrediente alimenticio rico en proteinas a partir de biomasa y metodos de produccion.
AU2017208094A1 (en) 2016-01-14 2018-08-09 Upside Foods, Inc. Methods for extending the replicative capacity of somatic cells during an ex vivo cultivation process
EP4424837A3 (en) 2017-05-06 2024-12-11 Upside Foods, Inc. Compositions and methods for increasing the culture density of a cellular biomass within a cultivation infrastructure
EP3638777A4 (en) 2017-07-13 2021-05-12 Memphis Meats, Inc. COMPOSITIONS AND METHODS FOR INCREASING THE EFFICIENCY OF CELL CULTURES FOR FOOD MANUFACTURING

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
Hollenberg SM et al, "Use of a conditional MyoD transcription factor in studies of MyoD trans-activation and muscle determination", Proceedings of the National Academy of Sciences, 1993, 90(17):8028-8032. *
Telugu BP et al, "Leukemia inhibitory factor (LIF)-dependent, pluripotent stem cells established from inner cell mass of porcine embryos", Journal of Biological Chemistry, 2011, 286(33):28948-28953. doi: 10.1074/jbc.M111.229468. *

Also Published As

Publication number Publication date
BR112016009803A2 (pt) 2017-12-05
IL245292B2 (en) 2023-02-01
AU2019202244B2 (en) 2021-09-23
CA2928726A1 (en) 2015-05-07
BR112016009803A8 (pt) 2018-01-30
JP2016535601A (ja) 2016-11-17
WO2015066377A1 (en) 2015-05-07
AU2019202244A1 (en) 2019-04-18
JP2020089381A (ja) 2020-06-11
US20210171912A1 (en) 2021-06-10
AU2014342180A1 (en) 2016-05-19
ES2782380T5 (es) 2023-05-08
EP3071040B2 (en) 2022-12-28
CN105899079A (zh) 2016-08-24
IL245292A0 (en) 2016-06-30
US20160227830A1 (en) 2016-08-11
US10920196B2 (en) 2021-02-16
US20160251625A1 (en) 2016-09-01
ES2782380T3 (es) 2020-09-14
BR112016009803B1 (pt) 2022-02-08
JP6728049B2 (ja) 2020-07-22
IL245292B (en) 2022-10-01
CN111154726A (zh) 2020-05-15
IL296889A (en) 2022-12-01
EP3071040B1 (en) 2020-01-01
EP3071040A1 (en) 2016-09-28
EP3071040A4 (en) 2017-06-21

Similar Documents

Publication Publication Date Title
AU2019202244B2 (en) Method for scalable skeletal muscle lineage specification and cultivation
Xu et al. A zebrafish embryo culture system defines factors that promote vertebrate myogenesis across species
ES2967942T3 (es) Generación de células beta funcionales a partir de progenitoras endocrinas derivadas de células madre pluripotentes humanas
EP2955223B1 (en) Production methods for megakaryocytes and platelets
JP6905938B2 (ja) プライム型多能性幹細胞のナイーブ型多能性幹細胞への復帰
EP3059308B1 (en) Method of inducing kidney from pluripotent stem cells
JP7307481B2 (ja) 始原生殖細胞/始原生殖細胞様細胞の維持増幅及び分化誘導方法
CA3053893A1 (en) Maintenance culture of induced pluripotent stem cell-derived intestinal stem cells
JP6351018B2 (ja) アミノ酸組成変更培地を用いた幹細胞の分化誘導方法、及び該培地を含む培地キット
CA3221942A1 (en) Foodstuffs comprising cells differentiated from engineered oligopotent stem cells
US11697798B2 (en) Enhanced differentiation and maturation of pluripotent stem cell-derived myogenic cells
US20240279613A1 (en) Method of producing enteroendocrine cell, enteroendocrine cell derived from pluripotent stem cell, culture medium or culture medium kit, and use thereof
HK1229164A1 (en) Method for scalable skeletal muscle lineage specification and cultivation
HK1229164B (en) Method for scalable skeletal muscle lineage specification and cultivation
Sandoval et al. Tumor suppressors inhibit reprogramming of African spiny mouse (Acomys) fibroblasts to induced pluripotent stem cells
WO2017073763A1 (ja) 多能性幹細胞の分化抵抗性を減弱する方法
JP7323966B1 (ja) 培養用組成物を製造する方法
JP2024534404A (ja) ヒト細胞を再プログラミングする方法
WO2023067090A1 (en) Ipsc induction and progeny derivation

Legal Events

Date Code Title Description
FGA Letters patent sealed or granted (standard patent)
HB Alteration of name in register

Owner name: THE CURATORS OF THE UNIVERSITY OF MISSOURI

Free format text: FORMER NAME(S): THE CURATORS OF THE UNIVERSITY OF MISSOURI; MEMPHIS MEATS, INC.

Owner name: UPSIDE FOODS, INC.

Free format text: FORMER NAME(S): THE CURATORS OF THE UNIVERSITY OF MISSOURI; MEMPHIS MEATS, INC.

MK14 Patent ceased section 143(a) (annual fees not paid) or expired