AU2014287044B2 - Elucidation of ion exchange chromatography input optimization - Google Patents

Elucidation of ion exchange chromatography input optimization Download PDF

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Publication number
AU2014287044B2
AU2014287044B2 AU2014287044A AU2014287044A AU2014287044B2 AU 2014287044 B2 AU2014287044 B2 AU 2014287044B2 AU 2014287044 A AU2014287044 A AU 2014287044A AU 2014287044 A AU2014287044 A AU 2014287044A AU 2014287044 B2 AU2014287044 B2 AU 2014287044B2
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confectionary
decorative stamp
decorative
block
kit
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AU2014287044A1 (en
Inventor
Daniel Mcdonald
Thomas PATAPOFF
Yajun Wang
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Genentech Inc
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Genentech Inc
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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/86—Signal analysis
    • G01N30/8658—Optimising operation parameters
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08—Selective adsorption, e.g. chromatography
    • B01D15/26—Selective adsorption, e.g. chromatography characterised by the separation mechanism
    • B01D15/36—Selective adsorption, e.g. chromatography characterised by the separation mechanism involving ionic interaction, e.g. ion-exchange, ion-pair, ion-suppression or ion-exclusion
    • B01D15/361—Ion-exchange
    • B01D15/362—Cation-exchange
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08—Selective adsorption, e.g. chromatography
    • B01D15/26—Selective adsorption, e.g. chromatography characterised by the separation mechanism
    • B01D15/36—Selective adsorption, e.g. chromatography characterised by the separation mechanism involving ionic interaction, e.g. ion-exchange, ion-pair, ion-suppression or ion-exclusion
    • B01D15/361—Ion-exchange
    • B01D15/363—Anion-exchange
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08—Selective adsorption, e.g. chromatography
    • B01D15/26—Selective adsorption, e.g. chromatography characterised by the separation mechanism
    • B01D15/38—Selective adsorption, e.g. chromatography characterised by the separation mechanism involving specific interaction not covered by one or more of groups B01D15/265 and B01D15/30 - B01D15/36, e.g. affinity, ligand exchange or chiral chromatography
    • B01D15/3847—Multimodal interactions
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/16—Extraction; Separation; Purification by chromatography
    • C07K1/165—Extraction; Separation; Purification by chromatography mixed-mode chromatography
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/16—Extraction; Separation; Purification by chromatography
    • C07K1/18—Ion-exchange chromatography
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/26—Conditioning of the fluid carrier; Flow patterns
    • G01N30/28—Control of physical parameters of the fluid carrier
    • G01N30/34—Control of physical parameters of the fluid carrier of fluid composition, e.g. gradient
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/96—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation using ion-exchange
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6854—Immunoglobulins
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6803—General methods of protein analysis not limited to specific proteins or families of proteins

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  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • Pathology (AREA)
  • Physics & Mathematics (AREA)
  • General Physics & Mathematics (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Biotechnology (AREA)
  • Cell Biology (AREA)
  • Microbiology (AREA)
  • Food Science & Technology (AREA)
  • Peptides Or Proteins (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Confectionery (AREA)
AU2014287044A 2013-07-12 2014-07-11 Elucidation of ion exchange chromatography input optimization Active AU2014287044B2 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201361845890P 2013-07-12 2013-07-12
US61/845,890 2013-07-12
PCT/US2014/046338 WO2015006686A1 (en) 2013-07-12 2014-07-11 Elucidation of ion exchange chromatography input optimization

Publications (2)

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AU2014287044A1 AU2014287044A1 (en) 2016-02-11
AU2014287044B2 true AU2014287044B2 (en) 2020-02-06

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AU2014287044A Active AU2014287044B2 (en) 2013-07-12 2014-07-11 Elucidation of ion exchange chromatography input optimization

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US (2) US10274466B2 (enExample)
EP (2) EP3536699A1 (enExample)
JP (2) JP6462681B2 (enExample)
KR (1) KR102251127B1 (enExample)
CN (1) CN105377873B (enExample)
AU (1) AU2014287044B2 (enExample)
BR (1) BR112016000231A8 (enExample)
CA (1) CA2918052A1 (enExample)
ES (1) ES2705700T3 (enExample)
HR (1) HRP20190071T1 (enExample)
IL (1) IL243305B (enExample)
MX (1) MX368107B (enExample)
PL (1) PL3019516T3 (enExample)
RU (1) RU2016104542A (enExample)
SG (1) SG11201600221YA (enExample)
SI (1) SI3019516T1 (enExample)
TR (1) TR201818966T4 (enExample)
WO (1) WO2015006686A1 (enExample)

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ES2705700T3 (es) 2013-07-12 2019-03-26 Hoffmann La Roche Elucidación de la optimización de entrada en cromatografía de intercambio iónico
CN107110835B (zh) 2014-11-12 2019-07-26 通用电气健康护理生物科学股份公司 用于确定实验参数对液相色谱协议的影响的方法和系统
GB2539420B (en) * 2015-06-16 2021-01-13 Cytiva Sweden Ab Determination of chromatography conditions
BR112020019882A2 (pt) * 2018-04-02 2021-01-05 Amgen Inc. Composições de erenumabe e seus usos
JP2021530247A (ja) * 2018-07-05 2021-11-11 オベーション ダイアグノスティクス エルエルシー 癌の診断のためのＢＣｌ−２抗体とイムノアッセイ
KR20200080748A (ko) * 2018-12-27 2020-07-07 주식회사 폴루스 음이온 교환 크로마토그래피를 이용한 인슐린 전구체의 정제방법
WO2024261724A1 (en) * 2023-06-23 2024-12-26 Lupin Limited Ion-exchange chromatography for separation and analysis of charge variants

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Also Published As

Publication number Publication date
US20160161455A1 (en) 2016-06-09
JP2019090818A (ja) 2019-06-13
WO2015006686A8 (en) 2018-10-04
MX368107B (es) 2019-09-18
EP3019516A1 (en) 2016-05-18
HRP20190071T1 (hr) 2019-02-22
WO2015006686A1 (en) 2015-01-15
HK1222183A1 (zh) 2017-06-23
US10274466B2 (en) 2019-04-30
RU2016104542A (ru) 2017-08-17
EP3536699A1 (en) 2019-09-11
CN105377873B (zh) 2021-03-30
PL3019516T3 (pl) 2019-04-30
IL243305A0 (en) 2016-03-31
KR102251127B1 (ko) 2021-05-11
SG11201600221YA (en) 2016-02-26
MX2016000181A (es) 2016-03-09
CA2918052A1 (en) 2015-01-15
KR20160030251A (ko) 2016-03-16
ES2705700T3 (es) 2019-03-26
EP3019516B1 (en) 2018-11-14
BR112016000231A8 (pt) 2019-12-31
CN105377873A (zh) 2016-03-02
TR201818966T4 (tr) 2019-01-21
IL243305B (en) 2019-09-26
SI3019516T1 (sl) 2019-02-28
JP6462681B2 (ja) 2019-01-30
US10921297B2 (en) 2021-02-16
JP2016529489A (ja) 2016-09-23
AU2014287044A1 (en) 2016-02-11
US20190310234A1 (en) 2019-10-10

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