AU2014281781B2 - Compositions and methods for joint health - Google Patents

Compositions and methods for joint health Download PDF

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Publication number
AU2014281781B2
AU2014281781B2 AU2014281781A AU2014281781A AU2014281781B2 AU 2014281781 B2 AU2014281781 B2 AU 2014281781B2 AU 2014281781 A AU2014281781 A AU 2014281781A AU 2014281781 A AU2014281781 A AU 2014281781A AU 2014281781 B2 AU2014281781 B2 AU 2014281781B2
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AU
Australia
Prior art keywords
extract
morus
joint
composition
extracts
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Active
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AU2014281781A
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English (en)
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AU2014281781A1 (en
Inventor
Lidia Alfaro Brownell
Min Chu
Mei-Feng Hong
Eu-Jin HYUN
Qi Jia
Ping JIAO
Hyun-Jin Kim
Mi-Ran Kim
Tae-Woo Kim
Bo-Su LEE
Young-Chul Lee
Breanna MOORE
Jeong-Bum Nam
Mi-Sun Oh
Mi-Hye PARK
Mesfin Yimam
Qian Zhang
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Unigen Inc
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Unigen Inc
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Publication of AU2014281781A1 publication Critical patent/AU2014281781A1/en
Application granted granted Critical
Publication of AU2014281781B2 publication Critical patent/AU2014281781B2/en
Priority to AU2019201188A priority Critical patent/AU2019201188B2/en
Priority to AU2021200432A priority patent/AU2021200432B2/en
Priority to AU2022252847A priority patent/AU2022252847A1/en
Active legal-status Critical Current
Anticipated expiration legal-status Critical

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/60Moraceae (Mulberry family), e.g. breadfruit or fig
    • A61K36/605Morus (mulberry)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/045Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
    • A61K31/05Phenols
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A61K31/352Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline 
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A61K31/352Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline 
    • A61K31/3533,4-Dihydrobenzopyrans, e.g. chroman, catechin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7008Compounds having an amino group directly attached to a carbon atom of the saccharide radical, e.g. D-galactosamine, ranimustine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7028Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7028Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
    • A61K31/7034Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7048Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/53Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • A61K36/534Mentha (mint)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/02Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Mycology (AREA)
  • Botany (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Medical Informatics (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Molecular Biology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Rheumatology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nutrition Science (AREA)
  • Food Science & Technology (AREA)
  • Polymers & Plastics (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
AU2014281781A 2013-06-17 2014-06-16 Compositions and methods for joint health Active AU2014281781B2 (en)

Priority Applications (3)

Application Number Priority Date Filing Date Title
AU2019201188A AU2019201188B2 (en) 2013-06-17 2019-02-20 Compositions and methods for joint health
AU2021200432A AU2021200432B2 (en) 2013-06-17 2021-01-22 Compositions and methods for joint health
AU2022252847A AU2022252847A1 (en) 2013-06-17 2022-10-14 Compositions and methods for joint health

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201361836113P 2013-06-17 2013-06-17
US61/836,113 2013-06-17
US201361895234P 2013-10-24 2013-10-24
US61/895,234 2013-10-24
PCT/US2014/042584 WO2014204866A1 (en) 2013-06-17 2014-06-16 Compositions and methods for joint health

Related Child Applications (1)

Application Number Title Priority Date Filing Date
AU2019201188A Division AU2019201188B2 (en) 2013-06-17 2019-02-20 Compositions and methods for joint health

Publications (2)

Publication Number Publication Date
AU2014281781A1 AU2014281781A1 (en) 2016-01-07
AU2014281781B2 true AU2014281781B2 (en) 2018-11-29

Family

ID=52105165

Family Applications (4)

Application Number Title Priority Date Filing Date
AU2014281781A Active AU2014281781B2 (en) 2013-06-17 2014-06-16 Compositions and methods for joint health
AU2019201188A Active AU2019201188B2 (en) 2013-06-17 2019-02-20 Compositions and methods for joint health
AU2021200432A Active AU2021200432B2 (en) 2013-06-17 2021-01-22 Compositions and methods for joint health
AU2022252847A Pending AU2022252847A1 (en) 2013-06-17 2022-10-14 Compositions and methods for joint health

Family Applications After (3)

Application Number Title Priority Date Filing Date
AU2019201188A Active AU2019201188B2 (en) 2013-06-17 2019-02-20 Compositions and methods for joint health
AU2021200432A Active AU2021200432B2 (en) 2013-06-17 2021-01-22 Compositions and methods for joint health
AU2022252847A Pending AU2022252847A1 (en) 2013-06-17 2022-10-14 Compositions and methods for joint health

Country Status (10)

Country Link
US (3) US11123393B2 (ko)
EP (1) EP3010928A4 (ko)
KR (5) KR102396831B1 (ko)
CN (3) CN111000898A (ko)
AU (4) AU2014281781B2 (ko)
CA (1) CA2915822C (ko)
HK (1) HK1224299A1 (ko)
NZ (2) NZ715027A (ko)
TW (3) TWI643631B (ko)
WO (1) WO2014204866A1 (ko)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3131636A4 (en) 2014-04-18 2018-01-10 OmniActive Health Technologies Limited Curcumin compositions and uses thereof
KR101954325B1 (ko) * 2014-06-16 2019-03-05 유니젠, 인크. 뼈 장애, 연골 장애, 또는 이 둘 다의 관리 또는 개선을 위한 조성물 및 방법
WO2016107894A1 (en) * 2014-12-31 2016-07-07 Sanovel Ilac Sanayi Ve Ticaret A.S. Composition for joint and cartilage disorders comprising flurbiprofen, glucosamine sulfate, chondroitin sulfate, hyaluronic acid and methylsulfonylmethane
DK3053458T3 (da) * 2015-01-28 2020-02-03 Paninkret Chemisch Pharmazeutisches Werk Gmbh Spraytørret sammensætning omfattende et acerola-frugtekstrakt, hydrolyseret colagen type II og chondroitinsulfat
KR101832897B1 (ko) 2015-05-26 2018-02-27 (주)뉴트리 모루신, 구와논 지 또는 상백피를 함유하는 근육 질환 예방 및 치료용 또는 근 기능 개선용 조성물
WO2020084005A1 (en) * 2018-10-23 2020-04-30 Myelopro Diagnostics And Research Gmbh Compounds targeting mutant calreticulin
KR101984260B1 (ko) * 2018-11-08 2019-05-30 정재우 하이드롤라이즈드 해면을 포함하는 관절 또는 근육 통증 완화용 조성물
CN109432115B (zh) * 2018-12-26 2020-11-03 王健 一种治疗原发性痛经的药物及其用途
CN110075104A (zh) * 2019-06-14 2019-08-02 贵州大学 Kuwanon H在制备抗骨质疏松药物中的应用
CN110368379A (zh) * 2019-06-14 2019-10-25 贵州大学 Kuwanon G在制备抗骨质疏松药物中的应用
CN110251504B (zh) * 2019-07-10 2022-02-18 长春中医药大学 桑根酮d的制备方法及医药新用途
US11090365B2 (en) 2019-08-08 2021-08-17 SVK Herbal Corporation Composition and methods for treating bone and joint disease including extract from crocodilos reptilia and herbs
US20210388160A1 (en) * 2020-04-30 2021-12-16 Kansas Soybean Commission Polyethylene glycol-functionalized triglyceride polyol polymers
WO2021225756A1 (en) * 2020-05-07 2021-11-11 Innophos, Llc Compositions and methods for joint health
CN111743891A (zh) * 2020-07-21 2020-10-09 温州医科大学附属第一医院 桑根酮g在制备治疗银屑病的药物中的用途
CN111956790A (zh) * 2020-08-17 2020-11-20 张会方 用于增加人体胶原蛋白及网状纤维的药物的制备方法
CN111759836A (zh) * 2020-08-24 2020-10-13 河南大学 异补骨脂色烯查耳酮在制备抗炎药物方面的应用
CN114847223B (zh) * 2022-02-19 2023-11-07 昆明理工大学 一种建立oa食蟹猴模型的方法

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20040185122A1 (en) * 1999-03-19 2004-09-23 Pharmacia Corporation Selective COX-2 inhibition from edible plant extracts
US7514469B2 (en) * 2002-04-30 2009-04-07 Unigen Pharmaceuticals, Inc. Formulation of a mixture of Free-B-ring flavonoids and flavans as a therapeutic agent

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS4842818B1 (ko) * 1970-08-31 1973-12-14
US7108868B2 (en) * 2002-03-22 2006-09-19 Unigen Pharmaceuticals, Inc. Isolation of a dual cox-2 and 5-lipoxygenase inhibitor from acacia
US20030165588A1 (en) * 2002-03-01 2003-09-04 Unigen Pharmaceuticals, Inc. Identification of free-B-ring flavonoids as potent COX-2 inhibitors
CN1267113C (zh) * 2002-05-14 2006-08-02 南京大学 桑枝提取物及其提取方法和用途
ITMI20031396A1 (it) * 2003-07-09 2005-01-10 Giuliani Spa Composizione per uso farmaceutico o dietetico o cosmetico dotata di attivita' antiossidante.
EP2444093A1 (en) * 2005-03-10 2012-04-25 Unigen, Inc. Formulation of a mixture of free-b-ring flavonoids and flavans as a therapeutic agent
WO2007139887A2 (en) * 2006-05-22 2007-12-06 Cargill, Incorporated Methods for treating bone or joint inflammation
US7416748B2 (en) * 2006-08-03 2008-08-26 Jose Angel Olade Rangel Arthritis phyto-nutraceutical synergistic composition
WO2008120220A1 (en) * 2007-04-03 2008-10-09 Ganga Raju Gokaraju Synergistic anti-inflammatory and antioxidant dietary supplement compositions
CN101032334A (zh) * 2007-04-17 2007-09-12 李永胜 一种降血压组合保健品
CN101148451A (zh) * 2007-05-16 2008-03-26 好维股份有限公司 一种口腔药物及口腔护理用品
WO2009097512A1 (en) * 2008-02-01 2009-08-06 Innovative Drug Discovery Inc. Herbal pharmaceutical compositions to treat inflammation and inflammation associated conditions and diseases
CN101317985A (zh) * 2008-07-15 2008-12-10 王跃进 小儿消化不良外用贴药
CN101412703B (zh) * 2008-11-17 2011-06-01 江苏科技大学 一种联产桑叶黄酮、多糖和生物碱的复合提取工艺
WO2010132776A1 (en) * 2009-05-14 2010-11-18 Rutgers, The State University Of New Jersey Oregano and mint anti-inflammatory compositions and methods
CN101797293B (zh) * 2010-04-15 2011-08-31 南京中医药大学 一种治疗颈椎病的中药枕芯及其制备方法
CN103127232A (zh) * 2013-03-14 2013-06-05 赵晓昂 桑叶方总提物及其制剂和用途
CN107375430B (zh) * 2017-08-14 2020-10-23 胡铭 一种具有防治糖尿病及并发症的姜黄素组合物

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20040185122A1 (en) * 1999-03-19 2004-09-23 Pharmacia Corporation Selective COX-2 inhibition from edible plant extracts
US7514469B2 (en) * 2002-04-30 2009-04-07 Unigen Pharmaceuticals, Inc. Formulation of a mixture of Free-B-ring flavonoids and flavans as a therapeutic agent

Non-Patent Citations (5)

* Cited by examiner, † Cited by third party
Title
"All-in-One Moisturising Lotion", MINTEL GNPD, Obtained from the Internet, <URL: http://www.gnpd.com/sinatra/recordpage/1189501>, Last Retrieved 10 August 2018, Published August 2009 according to MINTEL GNPD *
"Rich Cream Pact", MINTEL GNPD, Obtained from the Internet, <URL: http://www.gnpd.com/sinatra/recordpage/1498073>, Last Retrieved 10 August 2018, Published January 2011 according to MINTEL GNPD *
"Saffron Shine Face Blemish Balm SPF 20", MINTEL GNPD, Obtained from the Internet, <URL: http://www.gnpd.com/sinatra/recordpage/1824657>, Last Retrieved 10 August 2018, Published July 2012 according to MINTEL GNPD *
ALMEIDA, JACKSON ROBERTO GUEDES DA SILVA ET AL., "Medicinal plants and natural compounds from the genus Morus (Moraceae) with Hypoglycemic activity: A review", GLUCOSE TOLERANCE, INTECH, (2012-12-12), pages 189 - 206 *
BUTT M S ET AL, "Morus alba L. nature's functional tonic", TRENDS IN FOOD SCIENCE AND TECHNOLOGY, ELSEVIER SCIENCE PUBLISHERS, GB, vol. 19, no. 10, doi:10.1016/J.TIFS.2008.06.002, ISSN 0924-2244, (2008-10-01), pages 505 - 512, (2008-06-11) *

Also Published As

Publication number Publication date
KR20160014707A (ko) 2016-02-11
KR20210024688A (ko) 2021-03-05
AU2019201188A1 (en) 2019-03-14
KR102396831B1 (ko) 2022-05-11
CA2915822A1 (en) 2014-12-24
NZ715027A (en) 2019-04-26
US20230190852A1 (en) 2023-06-22
AU2021200432A1 (en) 2021-02-25
CN111000898A (zh) 2020-04-14
TW201536307A (zh) 2015-10-01
HK1224299A1 (zh) 2017-08-18
EP3010928A4 (en) 2017-01-04
AU2014281781A1 (en) 2016-01-07
AU2022252847A1 (en) 2022-11-17
AU2021200432B2 (en) 2022-11-17
CN115068574A (zh) 2022-09-20
NZ752822A (en) 2022-10-28
WO2014204866A1 (en) 2014-12-24
US20160067296A1 (en) 2016-03-10
AU2019201188B2 (en) 2020-10-22
KR102223071B1 (ko) 2021-03-04
CA2915822C (en) 2016-11-29
KR102078204B1 (ko) 2020-04-10
CN105452269B (zh) 2020-01-10
TW201904602A (zh) 2019-02-01
US20150072953A1 (en) 2015-03-12
TWI825378B (zh) 2023-12-11
TW202131940A (zh) 2021-09-01
KR20220064422A (ko) 2022-05-18
KR101952416B1 (ko) 2019-02-26
EP3010928A1 (en) 2016-04-27
TWI643631B (zh) 2018-12-11
TWI718432B (zh) 2021-02-11
KR20190020199A (ko) 2019-02-27
KR20200018724A (ko) 2020-02-19
CN105452269A (zh) 2016-03-30
US11123393B2 (en) 2021-09-21

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