AU2014244154B2 - Microemulsion topical delivery platform - Google Patents
Microemulsion topical delivery platform Download PDFInfo
- Publication number
- AU2014244154B2 AU2014244154B2 AU2014244154A AU2014244154A AU2014244154B2 AU 2014244154 B2 AU2014244154 B2 AU 2014244154B2 AU 2014244154 A AU2014244154 A AU 2014244154A AU 2014244154 A AU2014244154 A AU 2014244154A AU 2014244154 B2 AU2014244154 B2 AU 2014244154B2
- Authority
- AU
- Australia
- Prior art keywords
- oil
- eye
- surfactants
- api
- water
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
- A61K31/216—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acids having aromatic rings, e.g. benactizyne, clofibrate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/12—Ketones
- A61K31/122—Ketones having the oxygen directly attached to a ring, e.g. quinones, vitamin K1, anthralin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/192—Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/658—Medicinal preparations containing organic active ingredients o-phenolic cannabinoids, e.g. cannabidiol, cannabigerolic acid, cannabichromene or tetrahydrocannabinol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/34—Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0048—Eye, e.g. artificial tears
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
- A61K9/1075—Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Ophthalmology & Optometry (AREA)
- Dispersion Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Emergency Medicine (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Inorganic Chemistry (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201361784005P | 2013-03-14 | 2013-03-14 | |
| US61/784,005 | 2013-03-14 | ||
| PCT/US2014/025773 WO2014160079A1 (en) | 2013-03-14 | 2014-03-13 | Microemulsion topical delivery platform |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| AU2014244154A1 AU2014244154A1 (en) | 2015-09-24 |
| AU2014244154B2 true AU2014244154B2 (en) | 2018-08-09 |
Family
ID=50628949
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU2014244154A Active AU2014244154B2 (en) | 2013-03-14 | 2014-03-13 | Microemulsion topical delivery platform |
Country Status (12)
| Country | Link |
|---|---|
| US (2) | US8968775B2 (OSRAM) |
| EP (1) | EP2968139B1 (OSRAM) |
| JP (1) | JP6348567B2 (OSRAM) |
| CN (1) | CN105451718B (OSRAM) |
| AU (1) | AU2014244154B2 (OSRAM) |
| CA (1) | CA2905023C (OSRAM) |
| DK (1) | DK2968139T3 (OSRAM) |
| ES (1) | ES2673009T3 (OSRAM) |
| PL (1) | PL2968139T3 (OSRAM) |
| PT (1) | PT2968139T (OSRAM) |
| TR (1) | TR201808197T4 (OSRAM) |
| WO (1) | WO2014160079A1 (OSRAM) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2041156B1 (en) | 2006-07-13 | 2013-11-20 | Achillion Pharmaceuticals, Inc. | 4-amino-4-oxobutanoyl peptides as inhibitors of viral replication |
| ES2584534B1 (es) * | 2015-03-27 | 2017-03-13 | Retinset, S.L. | Formulación tópica oftálmica de bosentan |
| AU2017208970A1 (en) | 2016-01-18 | 2018-08-02 | Arisan Therapeutics | Adamatane derivatives for the treatment of filovirus infection |
| PT3266446T (pt) * | 2016-07-07 | 2019-01-30 | Salvat Lab Sa | Composição oftálmica compreendendo óleo de rícino e triglicérido de cadeia média |
| US11548893B2 (en) | 2017-07-15 | 2023-01-10 | Arisan Therapeutics Inc. | Enantiomerically pure adamantane carboxamides for the treatment of filovirus infection |
| EP3672587A4 (en) | 2017-08-27 | 2021-05-19 | Rhodes Technologies | PHARMACEUTICAL COMPOSITIONS INTENDED FOR THE TREATMENT OF OPHTHALMIC DISORDERS |
| WO2019099595A1 (en) | 2017-11-14 | 2019-05-23 | The Schepens Eye Research Institute, Inc. | NANO-EMULSION OF CBFβ-RUNX1 INHIBITOR FOR OCULAR DRUG DELIVERY |
| CN114245737A (zh) | 2019-06-11 | 2022-03-25 | 司斐股份有限公司 | 微乳剂组合物 |
| KR102676428B1 (ko) * | 2019-07-08 | 2024-06-19 | 가부시키가이샤 모레스코 | 마이크로에멀션을 조제하기 위한 조성물, 마이크로에멀션, 이들의 제조 방법, 및 마이크로에멀션의 이용 |
| WO2022107886A1 (ja) * | 2020-11-19 | 2022-05-27 | 学校法人日本大学 | 網膜循環障害及び網膜神経血管連関障害の改善用又は予防用点眼剤 |
| CN119789854A (zh) * | 2023-08-04 | 2025-04-08 | Ads医疗有限责任公司 | 用于递送眼科活性物的组合物和方法 |
| WO2025090133A1 (en) | 2023-10-23 | 2025-05-01 | Inmed Pharmaceuticals Inc. | Compositions and methods for use of cannabinol compounds in neuroprotection |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TWI398261B (zh) * | 2003-12-17 | 2013-06-11 | Alcon Inc | 血清類澱粉ａ基因於診斷及治療青光眼及鑑定抗青光眼劑上之用途 |
| US7915247B1 (en) * | 2006-08-21 | 2011-03-29 | Mutual Pharmaceutical Company, Inc. | Methods of use of fenofibric acid |
| WO2009042677A2 (en) * | 2007-09-24 | 2009-04-02 | Farjo Rafal A | Stat3 inhibiting compositions and methods |
| US8652443B2 (en) * | 2008-02-14 | 2014-02-18 | Precision Dermatology, Inc. | Foamable microemulsion compositions for topical administration |
| WO2012109673A1 (en) * | 2011-02-11 | 2012-08-16 | Psivida Us, Inc. | Methods of treating macular edema using antiedema therapeutics |
| WO2013049621A1 (en) * | 2011-09-29 | 2013-04-04 | The Board Of Regents Of The University Of Oklahoma | Ophthalmic compositions comprising ppar-alpha agonists and methods of production and use thereof |
-
2014
- 2014-03-13 EP EP14720786.4A patent/EP2968139B1/en active Active
- 2014-03-13 PL PL14720786T patent/PL2968139T3/pl unknown
- 2014-03-13 AU AU2014244154A patent/AU2014244154B2/en active Active
- 2014-03-13 JP JP2016501962A patent/JP6348567B2/ja active Active
- 2014-03-13 WO PCT/US2014/025773 patent/WO2014160079A1/en not_active Ceased
- 2014-03-13 DK DK14720786.4T patent/DK2968139T3/en active
- 2014-03-13 CN CN201480027477.7A patent/CN105451718B/zh active Active
- 2014-03-13 CA CA2905023A patent/CA2905023C/en active Active
- 2014-03-13 TR TR2018/08197T patent/TR201808197T4/tr unknown
- 2014-03-13 ES ES14720786.4T patent/ES2673009T3/es active Active
- 2014-03-13 PT PT147207864T patent/PT2968139T/pt unknown
- 2014-03-14 US US14/212,675 patent/US8968775B2/en active Active - Reinstated
-
2015
- 2015-02-24 US US14/630,073 patent/US9149453B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| US20140275263A1 (en) | 2014-09-18 |
| PL2968139T3 (pl) | 2018-10-31 |
| EP2968139A1 (en) | 2016-01-20 |
| AU2014244154A1 (en) | 2015-09-24 |
| US8968775B2 (en) | 2015-03-03 |
| ES2673009T3 (es) | 2018-06-19 |
| JP6348567B2 (ja) | 2018-06-27 |
| US9149453B2 (en) | 2015-10-06 |
| PT2968139T (pt) | 2018-06-18 |
| CN105451718B (zh) | 2018-09-28 |
| CA2905023C (en) | 2019-10-15 |
| JP2016512562A (ja) | 2016-04-28 |
| CA2905023A1 (en) | 2014-10-02 |
| US20150164846A1 (en) | 2015-06-18 |
| DK2968139T3 (en) | 2018-06-25 |
| TR201808197T4 (tr) | 2018-07-23 |
| CN105451718A (zh) | 2016-03-30 |
| WO2014160079A1 (en) | 2014-10-02 |
| EP2968139B1 (en) | 2018-05-23 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FGA | Letters patent sealed or granted (standard patent) |