AU2013370955B2 - Nanoparticle compositions of albumin and paclitaxel - Google Patents

Nanoparticle compositions of albumin and paclitaxel Download PDF

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Publication number
AU2013370955B2
AU2013370955B2 AU2013370955A AU2013370955A AU2013370955B2 AU 2013370955 B2 AU2013370955 B2 AU 2013370955B2 AU 2013370955 A AU2013370955 A AU 2013370955A AU 2013370955 A AU2013370955 A AU 2013370955A AU 2013370955 B2 AU2013370955 B2 AU 2013370955B2
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Australia
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composition
albumin
paclitaxel
pharmaceutical composition
nanoparticles
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AU2013370955A
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AU2013370955A1 (en
Inventor
Neil P. Desai
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Abraxis Bioscience LLC
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Abraxis Bioscience LLC
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/42—Proteins; Polypeptides; Degradation products thereof; Derivatives thereof, e.g. albumin, gelatin or zein
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/337—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having four-membered rings, e.g. taxol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/51—Nanocapsules; Nanoparticles
    • A61K9/5107—Excipients; Inactive ingredients
    • A61K9/513—Organic macromolecular compounds; Dendrimers
    • A61K9/5169—Proteins, e.g. albumin, gelatin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/04—Antineoplastic agents specific for metastasis

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nanotechnology (AREA)
  • Physics & Mathematics (AREA)
  • Biomedical Technology (AREA)
  • Optics & Photonics (AREA)
  • Oncology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Inorganic Chemistry (AREA)
  • Hematology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AU2013370955A 2012-12-28 2013-12-19 Nanoparticle compositions of albumin and paclitaxel Active AU2013370955B2 (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201261747123P 2012-12-28 2012-12-28
US61/747,123 2012-12-28
US13/794,705 2013-03-11
US13/794,705 US20140186447A1 (en) 2012-12-28 2013-03-11 Nanoparticle compositions of albumin and paclitaxel
PCT/US2013/076630 WO2014105644A1 (en) 2012-12-28 2013-12-19 Nanoparticle compositions of albumin and paclitaxel

Publications (2)

Publication Number Publication Date
AU2013370955A1 AU2013370955A1 (en) 2015-07-16
AU2013370955B2 true AU2013370955B2 (en) 2018-12-06

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AU2013370955A Active AU2013370955B2 (en) 2012-12-28 2013-12-19 Nanoparticle compositions of albumin and paclitaxel

Country Status (19)

Country Link
US (2) US20140186447A1 (enExample)
EP (1) EP2938340A4 (enExample)
JP (2) JP2016504362A (enExample)
KR (1) KR20150100903A (enExample)
CN (1) CN105007912A (enExample)
AU (1) AU2013370955B2 (enExample)
BR (1) BR112015015319A2 (enExample)
CA (1) CA2896288A1 (enExample)
CR (1) CR20150386A (enExample)
HK (1) HK1216611A1 (enExample)
IL (1) IL239593A0 (enExample)
MX (1) MX2015008361A (enExample)
NI (1) NI201500090A (enExample)
NZ (1) NZ630912A (enExample)
PH (1) PH12015501486B1 (enExample)
RU (1) RU2663687C2 (enExample)
SG (1) SG11201505111TA (enExample)
WO (1) WO2014105644A1 (enExample)
ZA (1) ZA201504762B (enExample)

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WO2008150532A1 (en) * 2007-06-01 2008-12-11 Abraxis Bioscience, Llc Methods and compositions for treating recurrent cancer
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US9370494B2 (en) 2010-03-26 2016-06-21 Abraxis Bioscience, Llc Methods for treating hepatocellular carcinoma
WO2011123395A1 (en) 2010-03-29 2011-10-06 Abraxis Bioscience, Llc Methods of treating cancer
EP2552439B1 (en) 2010-03-29 2022-07-20 Abraxis BioScience, LLC Methods of enhancing drug delivery and effectiveness of therapeutic agents
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US9427477B2 (en) 2011-05-09 2016-08-30 Mayo Foundation For Medical Education And Research Cancer treatments
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CN104224750A (zh) * 2014-09-17 2014-12-24 四川大学 一种注射用卡巴他赛白蛋白纳米粒制剂及其制备方法
US9446148B2 (en) 2014-10-06 2016-09-20 Mayo Foundation For Medical Education And Research Carrier-antibody compositions and methods of making and using the same
TW201628644A (zh) * 2014-11-25 2016-08-16 奈諾生技公司 醫藥組合物、其製備及其用途
PT3229776T (pt) 2014-11-25 2023-08-17 Curadigm Sas Composição farmacêutica combinando pelo menos duas nanopartícuas distintas e um composto farmacêutico, preparaçâo e suas utilizações
HUE067642T2 (hu) 2014-11-25 2024-11-28 Curadigm Sas Gyógyászati készítmény, elõállítása és alkalmazásai
ES2890662T3 (es) 2014-11-25 2022-01-21 Curadigm Sas Composiciones farmacéuticas, preparación y usos de las mismas
US10527604B1 (en) 2015-03-05 2020-01-07 Abraxis Bioscience, Llc Methods of assessing suitability of use of pharmaceutical compositions of albumin and paclitaxel
US10705070B1 (en) 2015-03-05 2020-07-07 Abraxis Bioscience, Llc Methods of assessing suitability of use of pharmaceutical compositions of albumin and poorly water soluble drug
BR112017025553A2 (pt) 2015-05-28 2018-08-07 Nanobiotix composição de vacina, e kit
MX381140B (es) 2015-06-29 2025-03-12 Abraxis Bioscience Llc Métodos para tratar tumores de células epitelioides.
TW201707725A (zh) 2015-08-18 2017-03-01 美國馬友醫藥教育研究基金會 載體－抗體組合物及其製造及使用方法
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WO2017165440A1 (en) 2016-03-21 2017-09-28 Mayo Foundation For Medical Education And Research Methods for reducing toxicity of a chemotherapeutic drug
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US10618969B2 (en) 2016-04-06 2020-04-14 Mayo Foundation For Medical Education And Research Carrier-binding agent compositions and methods of making and using the same
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CN106420665B (zh) * 2016-10-28 2019-04-16 浙江省林业科学研究院 一种包裹紫杉烷类药物的白蛋白纳米颗粒载体的制备方法
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Also Published As

Publication number Publication date
US20190192477A1 (en) 2019-06-27
US20140186447A1 (en) 2014-07-03
EP2938340A4 (en) 2016-08-03
CR20150386A (es) 2015-10-07
NI201500090A (es) 2015-12-22
WO2014105644A1 (en) 2014-07-03
MX2015008361A (es) 2016-03-11
IL239593A0 (en) 2015-08-31
SG11201505111TA (en) 2015-07-30
KR20150100903A (ko) 2015-09-02
BR112015015319A2 (pt) 2017-07-11
AU2013370955A1 (en) 2015-07-16
RU2015131141A (ru) 2017-02-03
PH12015501486B1 (en) 2020-12-16
HK1216611A1 (zh) 2016-11-25
NZ630912A (en) 2017-05-26
PH12015501486A1 (en) 2015-09-21
CA2896288A1 (en) 2014-07-03
JP2016504362A (ja) 2016-02-12
CN105007912A (zh) 2015-10-28
RU2663687C2 (ru) 2018-08-08
EP2938340A1 (en) 2015-11-04
ZA201504762B (en) 2016-10-26
JP2018087241A (ja) 2018-06-07

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