AU2013324396B2 - Fused heterocyclic compounds as selective BMP inhibitors - Google Patents
Fused heterocyclic compounds as selective BMP inhibitors Download PDFInfo
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- AU2013324396B2 AU2013324396B2 AU2013324396A AU2013324396A AU2013324396B2 AU 2013324396 B2 AU2013324396 B2 AU 2013324396B2 AU 2013324396 A AU2013324396 A AU 2013324396A AU 2013324396 A AU2013324396 A AU 2013324396A AU 2013324396 B2 AU2013324396 B2 AU 2013324396B2
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Landscapes
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| US9527835B2 (en) | 2014-02-13 | 2016-12-27 | Incyte Corporation | Cyclopropylamines as LSD1 inhibitors |
| JP6602779B2 (ja) | 2014-02-13 | 2019-11-06 | インサイト・コーポレイション | Ｌｓｄ１阻害剤としてのシクロプロピルアミン類 |
| EP3105218B1 (en) | 2014-02-13 | 2019-09-25 | Incyte Corporation | Cyclopropylamines as lsd1 inhibitors |
| WO2016007731A1 (en) | 2014-07-10 | 2016-01-14 | Incyte Corporation | Imidazopyridines and imidazopyrazines as lsd1 inhibitors |
| US9695180B2 (en) | 2014-07-10 | 2017-07-04 | Incyte Corporation | Substituted imidazo[1,2-a]pyrazines as LSD1 inhibitors |
| US9695167B2 (en) | 2014-07-10 | 2017-07-04 | Incyte Corporation | Substituted triazolo[1,5-a]pyridines and triazolo[1,5-a]pyrazines as LSD1 inhibitors |
| EP3277689B1 (en) | 2015-04-03 | 2019-09-04 | Incyte Corporation | Heterocyclic compounds as lsd1 inhibitors |
| WO2017024406A1 (en) | 2015-08-11 | 2017-02-16 | Neomed Institute | N-substituted bicyclic lactams, their preparation and their use as pharmaceuticals |
| JP2018527340A (ja) | 2015-08-11 | 2018-09-20 | ネオメド インスティテュートＮｅｏｍｅｄ Ｉｎｓｔｉｔｕｔｅ | アリール置換ジヒドロキノリノン、その調製及び医薬品としてのその使用 |
| MY189367A (en) | 2015-08-12 | 2022-02-08 | Incyte Corp | Salts of an lsd1 inhibitor |
| KR102784592B1 (ko) | 2015-08-12 | 2025-03-19 | 에피제네틱스, 인크. | 치환된 벤즈이미다졸, 그의 제조법 및 제약으로서의 그의 용도 |
| US10501459B2 (en) | 2015-10-21 | 2019-12-10 | Neomed Institute | Substituted imidazo[1,2-a]pyridines as bromodomain inhibitors |
| US10519151B2 (en) * | 2016-01-28 | 2019-12-31 | Neomed Institute | Substituted [1,2,4]triazolo[4,3-A]pyridines, their preparation and their use as pharmaceuticals |
| JP7023868B2 (ja) | 2016-06-08 | 2022-02-22 | クレメンティア ファーマシューティカルズ，インコーポレイテッド | 異所性骨化を治療するための方法 |
| MX388518B (es) * | 2016-07-20 | 2025-03-19 | Novartis Ag | Derivados de aminopiridina y su uso como inhibidores selectivos de alk-2. |
| US20190218214A1 (en) * | 2016-09-14 | 2019-07-18 | Vanderbilt University | Inhibition of BMP Signaling Compounds, Compositions and Uses Thereof |
| WO2018136634A1 (en) * | 2017-01-18 | 2018-07-26 | Vanderbilt University | Fused heterocyclic compounds as selective bmp inhibitors |
| WO2019178383A1 (en) * | 2018-03-14 | 2019-09-19 | Vanderbilt University | Inhibition of bmp signaling, compounds, compositions and uses thereof |
| CN110496127A (zh) * | 2018-05-17 | 2019-11-26 | 中国科学院上海生命科学研究院 | 一种热休克因子1的抑制剂、其制备方法和应用 |
| US10968200B2 (en) | 2018-08-31 | 2021-04-06 | Incyte Corporation | Salts of an LSD1 inhibitor and processes for preparing the same |
| CA3124088A1 (en) * | 2018-12-20 | 2020-06-25 | Incyte Corporation | Imidazopyridazine and imidazopyridine compounds as inhibitors of activin receptor-like kinase-2 |
| US20220372135A1 (en) | 2019-09-27 | 2022-11-24 | Disc Medicine, Inc. | Methods for treating myelofibrosis and related conditions |
| JP7717065B2 (ja) | 2019-11-22 | 2025-08-01 | インサイト コーポレーション | Ａｌｋ２阻害剤及びｊａｋ２阻害剤を含む併用療法 |
| KR20230012539A (ko) | 2020-05-13 | 2023-01-26 | 디스크 메디슨, 인크. | 골수섬유증을 치료하기 위한 항-헤모주벨린 (hjv) 항체 |
| WO2021257532A1 (en) | 2020-06-16 | 2021-12-23 | Incyte Corporation | Alk2 inhibitors for the treatment of anemia |
| WO2024205336A1 (ko) * | 2023-03-30 | 2024-10-03 | 에이치엘비생명과학알앤디 주식회사 | 튜블린 저해 활성을 갖는 약학적 조성물 |
| AU2023449758A1 (en) * | 2023-05-22 | 2025-12-11 | Iregene Therapeutics Co., Ltd | Use of bmpr1b inhibitor in induced induction of development, and induction culture medium |
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2013
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- 2013-03-15 CN CN201380058849.8A patent/CN104768548B/zh not_active Expired - Fee Related
- 2013-03-15 WO PCT/US2013/032588 patent/WO2014051698A1/en not_active Ceased
- 2013-03-15 ES ES13840866.1T patent/ES2660051T3/es active Active
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- 2013-03-15 SG SG11201503299YA patent/SG11201503299YA/en unknown
- 2013-03-15 EP EP13840866.1A patent/EP2900238B1/en not_active Not-in-force
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2017
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|---|---|
| US9738636B2 (en) | 2017-08-22 |
| EP2900238B1 (en) | 2017-12-06 |
| HK1206278A1 (en) | 2016-01-08 |
| CN104768548A (zh) | 2015-07-08 |
| ES2660051T3 (es) | 2018-03-20 |
| CA2886187C (en) | 2020-04-14 |
| WO2014051698A1 (en) | 2014-04-03 |
| BR112015007136A2 (pt) | 2018-05-15 |
| JP6430383B2 (ja) | 2018-11-28 |
| EP2900238A1 (en) | 2015-08-05 |
| AU2013324396A1 (en) | 2015-05-14 |
| US10196392B2 (en) | 2019-02-05 |
| KR102092988B1 (ko) | 2020-03-25 |
| JP2015531371A (ja) | 2015-11-02 |
| CA2886187A1 (en) | 2014-04-03 |
| CN104768548B (zh) | 2018-08-10 |
| US20160068525A1 (en) | 2016-03-10 |
| DK2900238T3 (en) | 2018-03-12 |
| KR20150064137A (ko) | 2015-06-10 |
| SG11201503299YA (en) | 2015-06-29 |
| EP2900238A4 (en) | 2016-04-06 |
| US20170313701A1 (en) | 2017-11-02 |
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