AU2013308131B2 - Multi plane mixer and separator (MPMS) system - Google Patents
Multi plane mixer and separator (MPMS) system Download PDFInfo
- Publication number
- AU2013308131B2 AU2013308131B2 AU2013308131A AU2013308131A AU2013308131B2 AU 2013308131 B2 AU2013308131 B2 AU 2013308131B2 AU 2013308131 A AU2013308131 A AU 2013308131A AU 2013308131 A AU2013308131 A AU 2013308131A AU 2013308131 B2 AU2013308131 B2 AU 2013308131B2
- Authority
- AU
- Australia
- Prior art keywords
- mpms
- container
- motor
- holding frame
- container holding
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Ceased
Links
- 238000002156 mixing Methods 0.000 claims abstract description 54
- 230000007246 mechanism Effects 0.000 claims abstract description 38
- 239000012530 fluid Substances 0.000 claims abstract description 3
- 239000007788 liquid Substances 0.000 claims description 36
- 230000033001 locomotion Effects 0.000 claims description 27
- 239000012472 biological sample Substances 0.000 claims description 13
- 210000001519 tissue Anatomy 0.000 description 20
- 210000004027 cell Anatomy 0.000 description 19
- 238000000034 method Methods 0.000 description 16
- 238000012545 processing Methods 0.000 description 16
- 238000005191 phase separation Methods 0.000 description 13
- 239000000872 buffer Substances 0.000 description 12
- 230000008569 process Effects 0.000 description 12
- 108090000790 Enzymes Proteins 0.000 description 11
- 102000004190 Enzymes Human genes 0.000 description 11
- 229940088598 enzyme Drugs 0.000 description 11
- 238000013019 agitation Methods 0.000 description 7
- 239000000463 material Substances 0.000 description 7
- 239000012071 phase Substances 0.000 description 7
- 238000010276 construction Methods 0.000 description 6
- 230000029087 digestion Effects 0.000 description 6
- 239000000203 mixture Substances 0.000 description 6
- 238000004062 sedimentation Methods 0.000 description 6
- 238000000926 separation method Methods 0.000 description 6
- 239000007787 solid Substances 0.000 description 6
- 239000000725 suspension Substances 0.000 description 6
- 230000002572 peristaltic effect Effects 0.000 description 5
- 239000000523 sample Substances 0.000 description 4
- 239000000243 solution Substances 0.000 description 4
- 239000000126 substance Substances 0.000 description 4
- 238000012546 transfer Methods 0.000 description 4
- 238000005406 washing Methods 0.000 description 4
- 210000001185 bone marrow Anatomy 0.000 description 3
- 238000001914 filtration Methods 0.000 description 3
- 238000010438 heat treatment Methods 0.000 description 3
- 239000011859 microparticle Substances 0.000 description 3
- -1 pharmaceutical Substances 0.000 description 3
- 239000004033 plastic Substances 0.000 description 3
- 229920003023 plastic Polymers 0.000 description 3
- 102000004169 proteins and genes Human genes 0.000 description 3
- 108090000623 proteins and genes Proteins 0.000 description 3
- 230000002792 vascular Effects 0.000 description 3
- 239000002699 waste material Substances 0.000 description 3
- 102000029816 Collagenase Human genes 0.000 description 2
- 108060005980 Collagenase Proteins 0.000 description 2
- 102000004127 Cytokines Human genes 0.000 description 2
- 108090000695 Cytokines Proteins 0.000 description 2
- 230000003213 activating effect Effects 0.000 description 2
- 239000000654 additive Substances 0.000 description 2
- 239000008346 aqueous phase Substances 0.000 description 2
- 210000004369 blood Anatomy 0.000 description 2
- 239000008280 blood Substances 0.000 description 2
- 239000007853 buffer solution Substances 0.000 description 2
- 230000008859 change Effects 0.000 description 2
- 238000005352 clarification Methods 0.000 description 2
- 229960002424 collagenase Drugs 0.000 description 2
- 238000013461 design Methods 0.000 description 2
- 238000010586 diagram Methods 0.000 description 2
- 102000038379 digestive enzymes Human genes 0.000 description 2
- 108091007734 digestive enzymes Proteins 0.000 description 2
- 230000000694 effects Effects 0.000 description 2
- 210000004700 fetal blood Anatomy 0.000 description 2
- 239000003102 growth factor Substances 0.000 description 2
- 238000000265 homogenisation Methods 0.000 description 2
- 239000003112 inhibitor Substances 0.000 description 2
- 238000007443 liposuction Methods 0.000 description 2
- 239000011159 matrix material Substances 0.000 description 2
- 239000002184 metal Substances 0.000 description 2
- 229910052755 nonmetal Inorganic materials 0.000 description 2
- 238000000746 purification Methods 0.000 description 2
- 238000011084 recovery Methods 0.000 description 2
- 238000003756 stirring Methods 0.000 description 2
- 238000001356 surgical procedure Methods 0.000 description 2
- 238000012360 testing method Methods 0.000 description 2
- 210000003954 umbilical cord Anatomy 0.000 description 2
- 108090000526 Papain Proteins 0.000 description 1
- 102000057297 Pepsin A Human genes 0.000 description 1
- 108090000284 Pepsin A Proteins 0.000 description 1
- 108091005804 Peptidases Proteins 0.000 description 1
- 102000035195 Peptidases Human genes 0.000 description 1
- 239000004743 Polypropylene Substances 0.000 description 1
- 239000004365 Protease Substances 0.000 description 1
- 235000004443 Ricinus communis Nutrition 0.000 description 1
- 241000700605 Viruses Species 0.000 description 1
- 239000000853 adhesive Substances 0.000 description 1
- 230000001070 adhesive effect Effects 0.000 description 1
- 239000012062 aqueous buffer Substances 0.000 description 1
- 239000012223 aqueous fraction Substances 0.000 description 1
- 239000011324 bead Substances 0.000 description 1
- 210000000601 blood cell Anatomy 0.000 description 1
- 239000003795 chemical substances by application Substances 0.000 description 1
- 230000001143 conditioned effect Effects 0.000 description 1
- 238000007796 conventional method Methods 0.000 description 1
- 238000012258 culturing Methods 0.000 description 1
- 239000006185 dispersion Substances 0.000 description 1
- 238000010494 dissociation reaction Methods 0.000 description 1
- 230000005593 dissociations Effects 0.000 description 1
- 238000004090 dissolution Methods 0.000 description 1
- 238000004945 emulsification Methods 0.000 description 1
- 239000000839 emulsion Substances 0.000 description 1
- DEFVIWRASFVYLL-UHFFFAOYSA-N ethylene glycol bis(2-aminoethyl)tetraacetic acid Chemical compound OC(=O)CN(CC(O)=O)CCOCCOCCN(CC(O)=O)CC(O)=O DEFVIWRASFVYLL-UHFFFAOYSA-N 0.000 description 1
- 238000004508 fractional distillation Methods 0.000 description 1
- 239000007789 gas Substances 0.000 description 1
- 239000001963 growth medium Substances 0.000 description 1
- 230000001939 inductive effect Effects 0.000 description 1
- 230000003993 interaction Effects 0.000 description 1
- 238000002955 isolation Methods 0.000 description 1
- 210000004185 liver Anatomy 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 239000002609 medium Substances 0.000 description 1
- 239000003607 modifier Substances 0.000 description 1
- 230000008520 organization Effects 0.000 description 1
- 210000000496 pancreas Anatomy 0.000 description 1
- 229940055729 papain Drugs 0.000 description 1
- 235000019834 papain Nutrition 0.000 description 1
- 239000002245 particle Substances 0.000 description 1
- 238000010951 particle size reduction Methods 0.000 description 1
- 229940111202 pepsin Drugs 0.000 description 1
- 210000002826 placenta Anatomy 0.000 description 1
- 239000004417 polycarbonate Substances 0.000 description 1
- 229920000515 polycarbonate Polymers 0.000 description 1
- 229920001155 polypropylene Polymers 0.000 description 1
- 238000005086 pumping Methods 0.000 description 1
- 238000005070 sampling Methods 0.000 description 1
- 210000002966 serum Anatomy 0.000 description 1
- 239000002002 slurry Substances 0.000 description 1
- 239000002904 solvent Substances 0.000 description 1
- 239000004094 surface-active agent Substances 0.000 description 1
- 210000005222 synovial tissue Anatomy 0.000 description 1
- 231100000331 toxic Toxicity 0.000 description 1
- 230000002588 toxic effect Effects 0.000 description 1
- 229920002554 vinyl polymer Polymers 0.000 description 1
- 239000011534 wash buffer Substances 0.000 description 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N1/00—Sampling; Preparing specimens for investigation
- G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
- G01N1/38—Diluting, dispersing or mixing samples
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
- B01F31/00—Mixers with shaking, oscillating, or vibrating mechanisms
- B01F31/20—Mixing the contents of independent containers, e.g. test tubes
- B01F31/26—Mixing the contents of independent containers, e.g. test tubes the containers being submitted to a wobbling movement
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
- B01F35/00—Accessories for mixers; Auxiliary operations or auxiliary devices; Parts or details of general application
- B01F35/50—Mixing receptacles
- B01F35/53—Mixing receptacles characterised by the configuration of the interior, e.g. baffles for facilitating the mixing of components
- B01F35/531—Mixing receptacles characterised by the configuration of the interior, e.g. baffles for facilitating the mixing of components with baffles, plates or bars on the wall or the bottom
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
- B01F35/00—Accessories for mixers; Auxiliary operations or auxiliary devices; Parts or details of general application
- B01F35/75—Discharge mechanisms
- B01F35/754—Discharge mechanisms characterised by the means for discharging the components from the mixer
- B01F35/7548—Discharge mechanisms characterised by the means for discharging the components from the mixer using tilting or pivoting means for emptying the mixing receptacle
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M45/00—Means for pre-treatment of biological substances
- C12M45/02—Means for pre-treatment of biological substances by mechanical forces; Stirring; Trituration; Comminuting
Landscapes
- Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Wood Science & Technology (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- Immunology (AREA)
- Pathology (AREA)
- Analytical Chemistry (AREA)
- General Physics & Mathematics (AREA)
- Physics & Mathematics (AREA)
- Molecular Biology (AREA)
- Microbiology (AREA)
- Sustainable Development (AREA)
- Biotechnology (AREA)
- Biomedical Technology (AREA)
- General Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Mechanical Engineering (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
- Accessories For Mixers (AREA)
- Mixers With Rotating Receptacles And Mixers With Vibration Mechanisms (AREA)
- Mixers Of The Rotary Stirring Type (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IN3514CH2012 | 2012-08-27 | ||
| IN3514/CHE/2012 | 2012-08-27 | ||
| PCT/IB2013/055938 WO2014033564A1 (en) | 2012-08-27 | 2013-07-19 | Multi plane mixer and separator (mpms) system |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| AU2013308131A1 AU2013308131A1 (en) | 2015-02-19 |
| AU2013308131B2 true AU2013308131B2 (en) | 2015-11-12 |
Family
ID=49165807
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU2013308131A Ceased AU2013308131B2 (en) | 2012-08-27 | 2013-07-19 | Multi plane mixer and separator (MPMS) system |
Country Status (8)
| Country | Link |
|---|---|
| EP (1) | EP2888032A1 (ja) |
| JP (1) | JP5875739B2 (ja) |
| KR (1) | KR101629877B1 (ja) |
| CN (1) | CN104519986A (ja) |
| AU (1) | AU2013308131B2 (ja) |
| BR (1) | BR112015001905A2 (ja) |
| HK (1) | HK1206671A1 (ja) |
| WO (1) | WO2014033564A1 (ja) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2992865B1 (fr) * | 2012-07-04 | 2014-08-29 | Maco Pharma Sa | Appareil pour extraire un composant sanguin contenu dans un systeme a poches |
| CN106919137B (zh) * | 2017-04-25 | 2023-08-15 | 李满发 | 细胞工厂自动控制系统 |
| JP7178012B2 (ja) * | 2018-10-29 | 2022-11-25 | 学校法人 中央大学 | 液体混合装置及び液体混合方法 |
| CN113092210B (zh) * | 2021-04-08 | 2022-06-24 | 昆明理工大学 | 具有可调节角度位置节理预制片的圆柱形试件浇筑模具 |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1995004591A1 (en) * | 1993-08-05 | 1995-02-16 | Max-Medical Pty. Ltd. | Device for mixing liquids |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2626741B2 (ja) * | 1992-02-19 | 1997-07-02 | 株式会社堀場製作所 | 遠心撹拌装置 |
| CN2134223Y (zh) * | 1992-09-25 | 1993-05-26 | 朱新青 | 一种摆动式混合机 |
| JP3353189B2 (ja) * | 1995-03-15 | 2002-12-03 | 株式会社サイニクス | 波動形に旋回揺動する振盪機 |
| US6491422B1 (en) * | 2000-05-16 | 2002-12-10 | Rütten Engineering | Mixer |
| CN1842589B (zh) * | 2003-06-25 | 2012-04-25 | 马克罗珀尔生物外科公司 | 用于从组织分离并且浓缩再生细胞的系统和方法 |
| JP4740749B2 (ja) * | 2006-01-17 | 2011-08-03 | 株式会社ジャパンユニックス | ミキサー |
| CN101063078B (zh) * | 2007-04-20 | 2010-06-09 | 博奥生物有限公司 | 一种生物芯片杂交清洗装置 |
| CN201140052Y (zh) * | 2007-12-12 | 2008-10-29 | 程若闻 | 液体混合器 |
| KR100866148B1 (ko) * | 2008-07-22 | 2008-10-30 | (주)세명 | 혼합기 |
| FR2952312B1 (fr) * | 2009-11-10 | 2011-12-02 | Jean Boquet | Appareil pour la vibration de tubes contenant des echantillons |
| KR101105239B1 (ko) * | 2011-12-14 | 2012-01-13 | 이미경 | 교반장치 |
-
2013
- 2013-07-19 CN CN201380039226.6A patent/CN104519986A/zh active Pending
- 2013-07-19 JP JP2015529144A patent/JP5875739B2/ja active Active
- 2013-07-19 BR BR112015001905A patent/BR112015001905A2/pt not_active IP Right Cessation
- 2013-07-19 WO PCT/IB2013/055938 patent/WO2014033564A1/en active Application Filing
- 2013-07-19 EP EP13762275.9A patent/EP2888032A1/en not_active Withdrawn
- 2013-07-19 KR KR1020157005104A patent/KR101629877B1/ko active IP Right Grant
- 2013-07-19 AU AU2013308131A patent/AU2013308131B2/en not_active Ceased
-
2015
- 2015-08-03 HK HK15107426.2A patent/HK1206671A1/xx unknown
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1995004591A1 (en) * | 1993-08-05 | 1995-02-16 | Max-Medical Pty. Ltd. | Device for mixing liquids |
Also Published As
| Publication number | Publication date |
|---|---|
| HK1206671A1 (en) | 2016-01-15 |
| CN104519986A (zh) | 2015-04-15 |
| BR112015001905A2 (pt) | 2017-07-04 |
| JP5875739B2 (ja) | 2016-03-02 |
| JP2015533631A (ja) | 2015-11-26 |
| WO2014033564A1 (en) | 2014-03-06 |
| KR20150038441A (ko) | 2015-04-08 |
| EP2888032A1 (en) | 2015-07-01 |
| AU2013308131A1 (en) | 2015-02-19 |
| KR101629877B1 (ko) | 2016-06-13 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FGA | Letters patent sealed or granted (standard patent) | ||
| MK14 | Patent ceased section 143(a) (annual fees not paid) or expired |