AU2013302526B2 - Exosome-based therapeutics against neurodegenerative disorders - Google Patents
Exosome-based therapeutics against neurodegenerative disorders Download PDFInfo
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- AU2013302526B2 AU2013302526B2 AU2013302526A AU2013302526A AU2013302526B2 AU 2013302526 B2 AU2013302526 B2 AU 2013302526B2 AU 2013302526 A AU2013302526 A AU 2013302526A AU 2013302526 A AU2013302526 A AU 2013302526A AU 2013302526 B2 AU2013302526 B2 AU 2013302526B2
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- A61K31/00—Medicinal preparations containing organic active ingredients
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- A61K35/15—Cells of the myeloid line, e.g. granulocytes, basophils, eosinophils, neutrophils, leucocytes, monocytes, macrophages or mast cells; Myeloid precursor cells; Antigen-presenting cells, e.g. dendritic cells
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- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
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- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
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- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/111—General methods applicable to biologically active non-coding nucleic acids
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- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
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- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/87—Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation
- C12N15/88—Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation using microencapsulation, e.g. using amphiphile liposome vesicle
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- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
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- C12N2310/00—Structure or type of the nucleic acid
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- C12N2320/00—Applications; Uses
- C12N2320/30—Special therapeutic applications
- C12N2320/32—Special delivery means, e.g. tissue-specific
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- Developmental Biology & Embryology (AREA)
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201261683596P | 2012-08-15 | 2012-08-15 | |
| US61/683,596 | 2012-08-15 | ||
| PCT/US2013/055187 WO2014028763A1 (en) | 2012-08-15 | 2013-08-15 | Exosome-based therapeutics against neurodegenerative disorders |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| AU2013302526A1 AU2013302526A1 (en) | 2015-04-02 |
| AU2013302526B2 true AU2013302526B2 (en) | 2018-03-22 |
Family
ID=50101510
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU2013302526A Active AU2013302526B2 (en) | 2012-08-15 | 2013-08-15 | Exosome-based therapeutics against neurodegenerative disorders |
Country Status (6)
| Country | Link |
|---|---|
| US (2) | US10231997B2 (enExample) |
| EP (1) | EP2885414B1 (enExample) |
| JP (1) | JP2015524849A (enExample) |
| AU (1) | AU2013302526B2 (enExample) |
| CA (1) | CA2882248A1 (enExample) |
| WO (1) | WO2014028763A1 (enExample) |
Families Citing this family (75)
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| CA2831613A1 (en) | 2011-03-31 | 2012-10-04 | Moderna Therapeutics, Inc. | Delivery and formulation of engineered nucleic acids |
| US9464124B2 (en) | 2011-09-12 | 2016-10-11 | Moderna Therapeutics, Inc. | Engineered nucleic acids and methods of use thereof |
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| US11369634B2 (en) | 2022-06-28 |
| JP2015524849A (ja) | 2015-08-27 |
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| CA2882248A1 (en) | 2014-02-20 |
| EP2885414A4 (en) | 2016-01-06 |
| US20150216899A1 (en) | 2015-08-06 |
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| AU2013302526A1 (en) | 2015-04-02 |
| US20190160097A1 (en) | 2019-05-30 |
| EP2885414A1 (en) | 2015-06-24 |
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