AU2013235487B2 - Treatment of pancreatic and related cancers with 5-acyl-6,7-dihydrothieno[3,2-c]pyridines - Google Patents
Treatment of pancreatic and related cancers with 5-acyl-6,7-dihydrothieno[3,2-c]pyridines Download PDFInfo
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- AU2013235487B2 AU2013235487B2 AU2013235487A AU2013235487A AU2013235487B2 AU 2013235487 B2 AU2013235487 B2 AU 2013235487B2 AU 2013235487 A AU2013235487 A AU 2013235487A AU 2013235487 A AU2013235487 A AU 2013235487A AU 2013235487 B2 AU2013235487 B2 AU 2013235487B2
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- alkyl
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Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
- A61K31/4365—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system having sulfur as a ring hetero atom, e.g. ticlopidine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D495/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201261614954P | 2012-03-23 | 2012-03-23 | |
| US61/614,954 | 2012-03-23 | ||
| PCT/US2013/031311 WO2013142253A2 (en) | 2012-03-23 | 2013-03-14 | TREATMENT OF PANCREATIC AND RELATED CANCERS WITH 5-ACYL-6,7-DIHYDROTHIENO[3,2-c]PYRIDINES |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| AU2013235487A1 AU2013235487A1 (en) | 2014-10-09 |
| AU2013235487B2 true AU2013235487B2 (en) | 2017-09-07 |
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ID=49223442
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU2013235487A Ceased AU2013235487B2 (en) | 2012-03-23 | 2013-03-14 | Treatment of pancreatic and related cancers with 5-acyl-6,7-dihydrothieno[3,2-c]pyridines |
Country Status (7)
| Country | Link |
|---|---|
| US (3) | US9242994B2 (https=) |
| EP (1) | EP2828267B1 (https=) |
| JP (1) | JP6117334B2 (https=) |
| CN (1) | CN104364257B (https=) |
| AU (1) | AU2013235487B2 (https=) |
| CA (1) | CA2868356C (https=) |
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| JP6117334B2 (ja) * | 2012-03-23 | 2017-04-19 | メモリアル スローン−ケタリング キャンサー センター | 膵臓癌および関連するがんの５−アシル−６，７−ジヒドロチエノ［３，２−ｃ］ピリジンでの処置 |
| WO2017218874A1 (en) * | 2016-06-16 | 2017-12-21 | Memorial Sloan-Kettering Cancer Center | Hedgehog acyltransferase inhibitors and uses thereof |
| WO2021212010A2 (en) * | 2020-04-17 | 2021-10-21 | The Trustees Of Indiana University | Small molecule antiviral drug treatment for human papillomavirus infections |
| EP4727553A2 (en) | 2023-06-13 | 2026-04-22 | The Trustees of Indiana University | Small molecule antiviral drug treatment for human papillomavirus infections |
| WO2025153715A1 (en) * | 2024-01-19 | 2025-07-24 | Scenic Biotech Bv | Heterocyclic pla2g15 inhibitors and their use in therapy, in the treatment of diseases characterized by lysosomal dysregulation |
Citations (1)
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| US20090197864A1 (en) * | 2008-02-06 | 2009-08-06 | Osi Pharmaceuticals, Inc. | Furo- and Thieno [3,2-c] Pyridines |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2315274A1 (fr) | 1975-06-27 | 1977-01-21 | Parcor | Nouveaux derives de la thieno (2,3-c) pyridine, leur preparation et leurs applications |
| US4749692A (en) | 1977-06-22 | 1988-06-07 | Sanofi, S.A. | Therapeutic compositions having anti-thrombotic and anti-blood-platelet-aggregating activity |
| JP2001514631A (ja) * | 1997-03-07 | 2001-09-11 | ノボ ノルディスク アクティーゼルスカブ | ４，５，６，７−テトラヒドロ−チエノ［３，２−ｃ］ピリジン誘導体類、それらの製造方法及び使用 |
| DE102005009440A1 (de) | 2005-03-02 | 2006-09-07 | Merck Patent Gmbh | Thienopyridinderivate |
| US8263607B2 (en) * | 2007-05-22 | 2012-09-11 | Astellas Pharma Inc. | 1-substituted tetrahydroisoquinoline compound |
| WO2009073203A1 (en) | 2007-12-04 | 2009-06-11 | Amgen Inc. | Trp-m8 receptor ligands and their use in treatments |
| TW200944530A (en) | 2008-04-09 | 2009-11-01 | Gruenenthal Chemie | Substituted sulfonamide derivatives |
| HRP20120822T1 (hr) * | 2008-10-24 | 2012-11-30 | Grünenthal GmbH | Supstituirani 4,5,6,7-tetrahidrotienopiridini kao kcnq2/3 modulatori za lijeäśenje boli, epilepsije i urinarne inkontinencije |
| WO2010101230A1 (ja) | 2009-03-05 | 2010-09-10 | アステラス製薬株式会社 | キノキサリン化合物 |
| EP2286808A1 (en) | 2009-08-18 | 2011-02-23 | Rheinische Friedrich-Wilhelms Universität | Cytohesin inhibitors |
| DE102010013716A1 (de) | 2010-03-31 | 2011-10-06 | Rheinische Friedrich-Wilhelms-Universität Bonn Körperschaft des öffentlichen Rechts | Verwendung von Cytohesin-Inhibitoren |
| JP6117334B2 (ja) * | 2012-03-23 | 2017-04-19 | メモリアル スローン−ケタリング キャンサー センター | 膵臓癌および関連するがんの５−アシル−６，７−ジヒドロチエノ［３，２−ｃ］ピリジンでの処置 |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20090197864A1 (en) * | 2008-02-06 | 2009-08-06 | Osi Pharmaceuticals, Inc. | Furo- and Thieno [3,2-c] Pyridines |
Also Published As
| Publication number | Publication date |
|---|---|
| EP2828267B1 (en) | 2019-10-30 |
| HK1207367A1 (en) | 2016-01-29 |
| WO2013142253A2 (en) | 2013-09-26 |
| US9242994B2 (en) | 2016-01-26 |
| CA2868356A1 (en) | 2013-09-26 |
| US20170252328A1 (en) | 2017-09-07 |
| US20160136142A1 (en) | 2016-05-19 |
| JP2015512399A (ja) | 2015-04-27 |
| US9943507B2 (en) | 2018-04-17 |
| AU2013235487A1 (en) | 2014-10-09 |
| CA2868356C (en) | 2020-06-23 |
| EP2828267A2 (en) | 2015-01-28 |
| EP2828267A4 (en) | 2015-10-28 |
| WO2013142253A3 (en) | 2013-11-14 |
| US20150105419A1 (en) | 2015-04-16 |
| CN104364257B (zh) | 2017-03-01 |
| CN104364257A (zh) | 2015-02-18 |
| JP6117334B2 (ja) | 2017-04-19 |
| US9597320B2 (en) | 2017-03-21 |
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