AU2012359081B2 - Combination therapy with interferon and andrographolides for multiple sclerosis - Google Patents

Combination therapy with interferon and andrographolides for multiple sclerosis Download PDF

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Publication number
AU2012359081B2
AU2012359081B2 AU2012359081A AU2012359081A AU2012359081B2 AU 2012359081 B2 AU2012359081 B2 AU 2012359081B2 AU 2012359081 A AU2012359081 A AU 2012359081A AU 2012359081 A AU2012359081 A AU 2012359081A AU 2012359081 B2 AU2012359081 B2 AU 2012359081B2
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AU
Australia
Prior art keywords
group
interferon
formula
compound
andrographolide
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Active
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AU2012359081A
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English (en)
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AU2012359081A1 (en
Inventor
Rafael Burgos
Juan L. Hancke Orozco
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INNOBIOSCIENCE LLC
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INNOBIOSCIENCE LLC
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First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=48669439&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=AU2012359081(B2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by INNOBIOSCIENCE LLC filed Critical INNOBIOSCIENCE LLC
Publication of AU2012359081A1 publication Critical patent/AU2012359081A1/en
Assigned to INNOBIOSCIENCE, LLC reassignment INNOBIOSCIENCE, LLC Request for Assignment Assignors: Herbal Powers Corporation
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Publication of AU2012359081B2 publication Critical patent/AU2012359081B2/en
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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/34—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
    • A61K31/341—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide not condensed with another ring, e.g. ranitidine, furosemide, bufetolol, muscarine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19—Cytokines; Lymphokines; Interferons
    • A61K38/21—Interferons [IFN]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19—Cytokines; Lymphokines; Interferons
    • A61K38/21—Interferons [IFN]
    • A61K38/215—IFN-beta
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Immunology (AREA)
  • Neurology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AU2012359081A 2011-12-21 2012-12-19 Combination therapy with interferon and andrographolides for multiple sclerosis Active AU2012359081B2 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201161578650P 2011-12-21 2011-12-21
US61/578,650 2011-12-21
PCT/US2012/070568 WO2013096423A1 (en) 2011-12-21 2012-12-19 Combination therapy with interferon and andrographolides for multiple sclerosis

Publications (2)

Publication Number Publication Date
AU2012359081A1 AU2012359081A1 (en) 2014-06-05
AU2012359081B2 true AU2012359081B2 (en) 2015-09-17

Family

ID=48669439

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2012359081A Active AU2012359081B2 (en) 2011-12-21 2012-12-19 Combination therapy with interferon and andrographolides for multiple sclerosis

Country Status (10)

Country Link
US (1) US9060994B2 (cg-RX-API-DMAC10.html)
EP (1) EP2670406B1 (cg-RX-API-DMAC10.html)
JP (1) JP5936707B2 (cg-RX-API-DMAC10.html)
AU (1) AU2012359081B2 (cg-RX-API-DMAC10.html)
BR (1) BR112014015178A2 (cg-RX-API-DMAC10.html)
CA (1) CA2853779C (cg-RX-API-DMAC10.html)
CL (1) CL2014001663A1 (cg-RX-API-DMAC10.html)
ES (1) ES2554459T3 (cg-RX-API-DMAC10.html)
RU (1) RU2014113967A (cg-RX-API-DMAC10.html)
WO (1) WO2013096423A1 (cg-RX-API-DMAC10.html)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN109562097B (zh) * 2016-06-08 2022-06-07 因诺生物科学有限责任公司 穿心莲内酯治疗多发性硬化的进行形式
US11318153B2 (en) 2018-06-25 2022-05-03 Bialpha International Sdn. Bhd. Method of using Neoandrographolide for lowering blood sugar, lowering blood lipid, improving liver function and improving renal function
CN109824655B (zh) * 2019-04-08 2021-09-24 沈阳药科大学 穿心莲内酯化合物及其制备方法和用途

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20050220764A1 (en) * 2004-04-01 2005-10-06 Schering Aktiengesellschaft Higher-doses of interferon-beta for treatment of multiple sclerosis

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1043027A1 (en) * 1999-04-08 2000-10-11 Applied Research Systems ARS Holding N.V. Treatment of multiple sclerosis with a combination of Interferon and Growth hormone
US6410590B1 (en) 2000-02-03 2002-06-25 Dr. Reddy's Research Foundation Compounds having antitumor activity: process for their preparation and pharmaceutical compositions containing them
US20050181033A1 (en) 2000-06-29 2005-08-18 Dekker John P.Iii Method for delivering interferons to the intradermal compartment
CA2463935A1 (en) 2001-09-18 2003-03-27 Chiron Corporation Methods for treating multiple sclerosis
AU2004315105A1 (en) * 2004-02-03 2005-08-18 Universidad Austral De Chile Composition of labdane diterpenes extracted from Andrographis paniculata, useful for the treatment of autoimmune diseases, and Alzheimer disease by activation of PPR-gamma receptors
US20080108641A1 (en) 2006-02-08 2008-05-08 Ajami Alfred M Compounds for treating inflammatory disorders, demyelinating disdorders and cancers
AU2010270971B2 (en) * 2009-06-22 2015-08-20 Sk Biopharmaceuticals Co., Ltd. Methods for treating or preventing fatigue

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20050220764A1 (en) * 2004-04-01 2005-10-06 Schering Aktiengesellschaft Higher-doses of interferon-beta for treatment of multiple sclerosis

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
PANITCH H. et al, The Lancet, 1987, Vol. 329(8538), pg. 839-895 *

Also Published As

Publication number Publication date
WO2013096423A1 (en) 2013-06-27
CA2853779C (en) 2016-04-26
JP2015500880A (ja) 2015-01-08
US9060994B2 (en) 2015-06-23
CA2853779A1 (en) 2013-06-27
US20140301981A1 (en) 2014-10-09
JP5936707B2 (ja) 2016-06-22
EP2670406B1 (en) 2015-09-02
ES2554459T3 (es) 2015-12-21
EP2670406A4 (en) 2014-05-28
NZ625051A (en) 2016-07-29
EP2670406A1 (en) 2013-12-11
RU2014113967A (ru) 2016-02-10
AU2012359081A1 (en) 2014-06-05
BR112014015178A2 (pt) 2017-06-13
CL2014001663A1 (es) 2015-02-27

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Owner name: INNOBIOSCIENCE, LLC

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MK5 Application lapsed section 142(2)(e) - patent request and compl. specification not accepted
NB Applications allowed - extensions of time section 223(2)

Free format text: THE TIME IN WHICH TO GAIN ACCEPTANCE HAS BEEN EXTENDED TO 25 SEP 2015 .

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