AU2012337087B2 - Therapeutic agent for arthrosis - Google Patents
Therapeutic agent for arthrosis Download PDFInfo
- Publication number
- AU2012337087B2 AU2012337087B2 AU2012337087A AU2012337087A AU2012337087B2 AU 2012337087 B2 AU2012337087 B2 AU 2012337087B2 AU 2012337087 A AU2012337087 A AU 2012337087A AU 2012337087 A AU2012337087 A AU 2012337087A AU 2012337087 B2 AU2012337087 B2 AU 2012337087B2
- Authority
- AU
- Australia
- Prior art keywords
- group
- phosphatidic acid
- formula
- arthrosis
- carbon atoms
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/6564—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having phosphorus atoms, with or without nitrogen, oxygen, sulfur, selenium or tellurium atoms, as ring hetero atoms
- C07F9/6571—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having phosphorus atoms, with or without nitrogen, oxygen, sulfur, selenium or tellurium atoms, as ring hetero atoms having phosphorus and oxygen atoms as the only ring hetero atoms
- C07F9/657163—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having phosphorus atoms, with or without nitrogen, oxygen, sulfur, selenium or tellurium atoms, as ring hetero atoms having phosphorus and oxygen atoms as the only ring hetero atoms the ring phosphorus atom being bound to at least one carbon atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/66—Phosphorus compounds
- A61K31/661—Phosphorus acids or esters thereof not having P—C bonds, e.g. fosfosal, dichlorvos, malathion or mevinphos
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/66—Phosphorus compounds
- A61K31/662—Phosphorus acids or esters thereof having P—C bonds, e.g. foscarnet, trichlorfon
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A61P29/02—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID] without antiinflammatory effect
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2121/00—Preparations for use in therapy
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Organic Chemistry (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Rheumatology (AREA)
- Engineering & Computer Science (AREA)
- Pain & Pain Management (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Physical Education & Sports Medicine (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Immunology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2011-247047 | 2011-11-11 | ||
| JP2011247047 | 2011-11-11 | ||
| PCT/JP2012/076478 WO2013069404A1 (ja) | 2011-11-11 | 2012-10-12 | 関節症治療剤 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| AU2012337087A1 AU2012337087A1 (en) | 2014-06-05 |
| AU2012337087B2 true AU2012337087B2 (en) | 2016-11-17 |
Family
ID=48289788
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU2012337087A Active AU2012337087B2 (en) | 2011-11-11 | 2012-10-12 | Therapeutic agent for arthrosis |
Country Status (15)
| Country | Link |
|---|---|
| US (1) | US9085593B2 (OSRAM) |
| EP (1) | EP2803359B1 (OSRAM) |
| JP (1) | JP5465815B2 (OSRAM) |
| KR (1) | KR101953181B1 (OSRAM) |
| CN (1) | CN103906519B (OSRAM) |
| AU (1) | AU2012337087B2 (OSRAM) |
| BR (1) | BR112014011315B8 (OSRAM) |
| CA (1) | CA2855660C (OSRAM) |
| ES (1) | ES2634008T3 (OSRAM) |
| IN (1) | IN2014CN04222A (OSRAM) |
| MY (1) | MY168931A (OSRAM) |
| PH (1) | PH12014501058B1 (OSRAM) |
| RU (1) | RU2646457C2 (OSRAM) |
| SG (1) | SG11201402226PA (OSRAM) |
| WO (1) | WO2013069404A1 (OSRAM) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3483169B1 (en) | 2014-08-12 | 2021-05-26 | Otsuka Chemical Co., Ltd. | Crystal of cyclic phosphonic acid sodium salt and method for manufacturing same |
| JP6727596B1 (ja) | 2019-11-22 | 2020-07-22 | 国立大学法人お茶の水女子大学 | カルバリゾホスファチジン酸 |
| TWI868287B (zh) | 2019-12-23 | 2025-01-01 | 日商大塚化學股份有限公司 | carba-環狀磷脂酸化合物 |
| JP7736256B2 (ja) * | 2020-11-13 | 2025-09-09 | 株式会社マツモト交商 | 環状ホスファチジン酸含有組成物及び美容方法 |
| JPWO2022114058A1 (OSRAM) | 2020-11-26 | 2022-06-02 |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2004010582A (ja) * | 2002-06-11 | 2004-01-15 | Gencom Co | カルバ環状ホスファチジン酸誘導体 |
| US20040204383A1 (en) * | 2003-04-11 | 2004-10-14 | Gabor Tigyi | Lysophosphatidic acid analogs and inhibition of neointima formation |
| US20040214799A1 (en) * | 2001-05-21 | 2004-10-28 | Mutsuko Mukai | Cancerous metastasis inhibitors containing carbacyclic phosphatidic acid derivatives |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2700350B2 (ja) | 1990-04-20 | 1998-01-21 | 小糸工業株式会社 | 車両感知器 |
| JP3195833B2 (ja) | 1991-09-30 | 2001-08-06 | きみ子 室伏 | 新規生理活性物質及びその製造法 |
| JPH07149772A (ja) * | 1993-11-26 | 1995-06-13 | Sagami Chem Res Center | タンパク質リン酸化酵素cの活性促進剤 |
| JPH07258278A (ja) | 1994-03-18 | 1995-10-09 | Sagami Chem Res Center | 1−O−アシルグリセロール−2,3−ホスフェート誘導体を有効成分とするDNAポリメラーゼαの阻害剤 |
| JPH0925235A (ja) | 1995-07-13 | 1997-01-28 | Sagami Chem Res Center | 1−o−アシルグリセロール−2,3−ホスフェート誘導体を有効成分とするがん転移抑制剤 |
| JP2001178489A (ja) | 1999-12-24 | 2001-07-03 | Kimiko Murofushi | 環状ホスファチジン酸の製造法 |
| JP4836345B2 (ja) * | 2001-04-13 | 2011-12-14 | きみ子 室伏 | 環状ホスファチジン酸誘導体を含む神経細胞の生存促進剤 |
| JP4815063B2 (ja) * | 2001-04-13 | 2011-11-16 | きみ子 室伏 | 環状ホスファチジン酸を含むグリア細胞の増殖、分化及び/又は生存の促進のための薬剤 |
| RU2240131C1 (ru) * | 2003-04-04 | 2004-11-20 | Аладьев Сергей Иванович | Средство "артровит" для профилактики и лечения артритов и артрозов |
| KR20070107046A (ko) | 2005-02-16 | 2007-11-06 | 쉐링 코포레이션 | Cxcr3 길항제 활성을 지닌 헤테로사이클릭 치환된피페라진 |
| US20090326256A1 (en) * | 2006-12-28 | 2009-12-31 | Ochanomizu University | Analgesic agent comprising cyclic phosphatidic acid derivative |
| JP2010189315A (ja) * | 2009-02-18 | 2010-09-02 | Unitika Ltd | 関節軟骨損傷治癒促進剤及びそれを含有する飲食品 |
-
2012
- 2012-10-12 JP JP2013542900A patent/JP5465815B2/ja active Active
- 2012-10-12 BR BR112014011315A patent/BR112014011315B8/pt active IP Right Grant
- 2012-10-12 CA CA2855660A patent/CA2855660C/en active Active
- 2012-10-12 WO PCT/JP2012/076478 patent/WO2013069404A1/ja not_active Ceased
- 2012-10-12 CN CN201280055135.7A patent/CN103906519B/zh active Active
- 2012-10-12 RU RU2014123690A patent/RU2646457C2/ru active
- 2012-10-12 ES ES12847890.6T patent/ES2634008T3/es active Active
- 2012-10-12 KR KR1020147015608A patent/KR101953181B1/ko active Active
- 2012-10-12 AU AU2012337087A patent/AU2012337087B2/en active Active
- 2012-10-12 IN IN4222CHN2014 patent/IN2014CN04222A/en unknown
- 2012-10-12 US US14/357,089 patent/US9085593B2/en active Active
- 2012-10-12 MY MYPI2014701211A patent/MY168931A/en unknown
- 2012-10-12 PH PH1/2014/501058A patent/PH12014501058B1/en unknown
- 2012-10-12 EP EP12847890.6A patent/EP2803359B1/en active Active
- 2012-10-12 SG SG11201402226PA patent/SG11201402226PA/en unknown
Patent Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20040214799A1 (en) * | 2001-05-21 | 2004-10-28 | Mutsuko Mukai | Cancerous metastasis inhibitors containing carbacyclic phosphatidic acid derivatives |
| JP2004010582A (ja) * | 2002-06-11 | 2004-01-15 | Gencom Co | カルバ環状ホスファチジン酸誘導体 |
| US20060122155A1 (en) * | 2002-06-11 | 2006-06-08 | Kimiko Murofushi | Carbacyclic phosphatidic acid derivative |
| US7550449B2 (en) * | 2002-06-11 | 2009-06-23 | Kimiko Murofushi | Carba cyclic phosphatidic acid derivative |
| US20040204383A1 (en) * | 2003-04-11 | 2004-10-14 | Gabor Tigyi | Lysophosphatidic acid analogs and inhibition of neointima formation |
Also Published As
| Publication number | Publication date |
|---|---|
| CA2855660C (en) | 2019-04-16 |
| NZ624870A (en) | 2016-01-29 |
| MY168931A (en) | 2019-01-09 |
| KR20140098778A (ko) | 2014-08-08 |
| JP5465815B2 (ja) | 2014-04-09 |
| AU2012337087A1 (en) | 2014-06-05 |
| CN103906519B (zh) | 2017-10-10 |
| CN103906519A (zh) | 2014-07-02 |
| BR112014011315A2 (pt) | 2017-05-09 |
| RU2646457C2 (ru) | 2018-03-05 |
| PH12014501058B1 (en) | 2019-11-08 |
| EP2803359B1 (en) | 2017-04-19 |
| RU2014123690A (ru) | 2015-12-20 |
| BR112014011315B8 (pt) | 2020-09-15 |
| WO2013069404A1 (ja) | 2013-05-16 |
| JPWO2013069404A1 (ja) | 2015-04-02 |
| US9085593B2 (en) | 2015-07-21 |
| PH12014501058A1 (en) | 2014-06-23 |
| KR101953181B1 (ko) | 2019-02-28 |
| ES2634008T3 (es) | 2017-09-26 |
| IN2014CN04222A (OSRAM) | 2015-07-17 |
| EP2803359A4 (en) | 2015-12-16 |
| BR112014011315B1 (pt) | 2020-03-03 |
| SG11201402226PA (en) | 2014-10-30 |
| HK1199406A1 (en) | 2015-07-03 |
| CA2855660A1 (en) | 2013-05-16 |
| US20140309194A1 (en) | 2014-10-16 |
| EP2803359A1 (en) | 2014-11-19 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| DA3 | Amendments made section 104 |
Free format text: THE NATURE OF THE AMENDMENT IS: AMEND THE INVENTION TITLE TO READ THERAPEUTIC AGENT FOR ARTHROSIS |
|
| FGA | Letters patent sealed or granted (standard patent) |