AU2012272646B2 - Organic compounds - Google Patents
Organic compounds Download PDFInfo
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- AU2012272646B2 AU2012272646B2 AU2012272646A AU2012272646A AU2012272646B2 AU 2012272646 B2 AU2012272646 B2 AU 2012272646B2 AU 2012272646 A AU2012272646 A AU 2012272646A AU 2012272646 A AU2012272646 A AU 2012272646A AU 2012272646 B2 AU2012272646 B2 AU 2012272646B2
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- compound
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- pharmaceutically acceptable
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- 150000002894 organic compounds Chemical class 0.000 title description 3
- 150000001875 compounds Chemical class 0.000 claims abstract description 249
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- 238000011282 treatment Methods 0.000 claims abstract description 41
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- 125000000217 alkyl group Chemical group 0.000 claims description 41
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- 208000035475 disorder Diseases 0.000 claims description 28
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 claims description 28
- 150000003839 salts Chemical group 0.000 claims description 28
- 125000003944 tolyl group Chemical group 0.000 claims description 21
- 125000001436 propyl group Chemical group [H]C([*])([H])C([H])([H])C([H])([H])[H] 0.000 claims description 20
- 229910052736 halogen Inorganic materials 0.000 claims description 19
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 claims description 18
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- 125000001495 ethyl group Chemical group [H]C([H])([H])C([H])([H])* 0.000 claims description 18
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| AUPCT/US2011/041866 | 2011-06-24 | ||
| US201161501207P | 2011-06-25 | 2011-06-25 | |
| US61/501,207 | 2011-06-25 | ||
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| US11491150B2 (en) | 2017-05-22 | 2022-11-08 | Intra-Cellular Therapies, Inc. | Organic compounds |
| WO2019152680A1 (en) * | 2018-01-31 | 2019-08-08 | Flagship Pioneering Innovations V, Inc. | Methods and compositions for treating cancer using chrna6 inhibitors |
| US12396992B2 (en) | 2019-01-07 | 2025-08-26 | Intra-Cellular Therapies, Inc. | Organic compounds |
| WO2021008565A1 (zh) * | 2019-07-16 | 2021-01-21 | 清华大学 | 乙酰胆碱通路调节剂在治疗癌症中的用途 |
| AU2020343329C1 (en) | 2019-09-03 | 2026-02-12 | Intra-Cellular Therapies, Inc. | Methods of treatment |
| EP4238970A1 (en) * | 2022-03-03 | 2023-09-06 | InterAx Biotech AG | Modulators of ackr3 and uses thereof |
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| JP2006525355A (ja) * | 2003-05-01 | 2006-11-09 | アボット・ラボラトリーズ | ナトリウムチャンネルモジュレーターとしてのピラゾール−アミドおよびスルホンアミド |
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Non-Patent Citations (2)
| Title |
|---|
| Chemical Abstracts Accession Number 141:395577 * |
| PENG, Y. ET AL., Bioorganic and Medicinal Chemistry Letters, 2010, Vol. 20, pages 4825-4830 * |
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| CA2840047A1 (en) | 2012-12-27 |
| US9708294B2 (en) | 2017-07-18 |
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| RU2014102191A (ru) | 2015-07-27 |
| WO2012178112A1 (en) | 2012-12-27 |
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