AU2012245871A1 - Pantothenic acid biosynthesis in Zymomonas - Google Patents

Pantothenic acid biosynthesis in Zymomonas Download PDF

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Publication number
AU2012245871A1
AU2012245871A1 AU2012245871A AU2012245871A AU2012245871A1 AU 2012245871 A1 AU2012245871 A1 AU 2012245871A1 AU 2012245871 A AU2012245871 A AU 2012245871A AU 2012245871 A AU2012245871 A AU 2012245871A AU 2012245871 A1 AU2012245871 A1 AU 2012245871A1
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AU
Australia
Prior art keywords
aspartate
polypeptide
decarboxylase
strain
activity
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2012245871A
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English (en)
Inventor
Luan Tao
Jean-Francois Tomb
Paul V. Viitanen
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
EIDP Inc
Original Assignee
EI Du Pont de Nemours and Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by EI Du Pont de Nemours and Co filed Critical EI Du Pont de Nemours and Co
Publication of AU2012245871A1 publication Critical patent/AU2012245871A1/en
Abandoned legal-status Critical Current

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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/74Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004Oxidoreductases (1.)
    • C12N9/0006Oxidoreductases (1.) acting on CH-OH groups as donors (1.1)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/88Lyases (4.)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00Preparation of nitrogen-containing organic compounds
    • C12P13/02Amides, e.g. chloramphenicol or polyamides; Imides or polyimides; Urethanes, i.e. compounds comprising N-C=O structural element or polyurethanes
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00Preparation of oxygen-containing organic compounds
    • C12P7/02Preparation of oxygen-containing organic compounds containing a hydroxy group
    • C12P7/04Preparation of oxygen-containing organic compounds containing a hydroxy group acyclic
    • C12P7/06Ethanol, i.e. non-beverage
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00Preparation of oxygen-containing organic compounds
    • C12P7/02Preparation of oxygen-containing organic compounds containing a hydroxy group
    • C12P7/04Preparation of oxygen-containing organic compounds containing a hydroxy group acyclic
    • C12P7/06Ethanol, i.e. non-beverage
    • C12P7/065Ethanol, i.e. non-beverage with microorganisms other than yeasts
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y101/00Oxidoreductases acting on the CH-OH group of donors (1.1)
    • C12Y101/01Oxidoreductases acting on the CH-OH group of donors (1.1) with NAD+ or NADP+ as acceptor (1.1.1)
    • C12Y101/011692-Dehydropantoate 2-reductase (1.1.1.169), i.e. ketopantoate-reductase
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y401/00Carbon-carbon lyases (4.1)
    • C12Y401/01Carboxy-lyases (4.1.1)
    • C12Y401/01011Aspartate 1-decarboxylase (4.1.1.11)
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02EREDUCTION OF GREENHOUSE GAS [GHG] EMISSIONS, RELATED TO ENERGY GENERATION, TRANSMISSION OR DISTRIBUTION
    • Y02E50/00Technologies for the production of fuel of non-fossil origin
    • Y02E50/10Biofuels, e.g. bio-diesel

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
AU2012245871A 2011-04-07 2012-04-06 Pantothenic acid biosynthesis in Zymomonas Abandoned AU2012245871A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201161472664P 2011-04-07 2011-04-07
US61/472,664 2011-04-07
PCT/US2012/032558 WO2012145179A1 (en) 2011-04-07 2012-04-06 Pantothenic acid biosynthesis in zymomonas

Publications (1)

Publication Number Publication Date
AU2012245871A1 true AU2012245871A1 (en) 2013-08-15

Family

ID=46026912

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2012245871A Abandoned AU2012245871A1 (en) 2011-04-07 2012-04-06 Pantothenic acid biosynthesis in Zymomonas

Country Status (8)

Country Link
US (1) US8765426B2 (enExample)
EP (1) EP2694648A1 (enExample)
JP (1) JP2014511699A (enExample)
CN (1) CN103476927A (enExample)
AU (1) AU2012245871A1 (enExample)
BR (1) BR112013025716A2 (enExample)
CA (1) CA2832559A1 (enExample)
WO (1) WO2012145179A1 (enExample)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20130316364A1 (en) 2012-05-23 2013-11-28 Lanzatech New Zealand Limited Selection Method and Recombinant Microorganisms and uses Therefor
WO2014087184A1 (en) * 2012-12-03 2014-06-12 Metabolic Explorer Neopentyl glycol fermentative production by a recombinant microorganism
US9580758B2 (en) 2013-11-12 2017-02-28 Luc Montagnier System and method for the detection and treatment of infection by a microbial agent associated with HIV infection
CN110835610B (zh) * 2018-08-17 2022-08-26 吉林农业大学 一种适用于降解秸秆的复合菌剂及制备方法
CN109402097A (zh) * 2018-10-23 2019-03-01 江南大学 一种L-天冬氨酸α-脱羧酶的基因工程菌株以及应用
CN110055188A (zh) * 2019-03-07 2019-07-26 南京师范大学 一株产抑菌肽的多粘类芽孢杆菌xw4及其分离筛选和应用
JP7028904B2 (ja) * 2019-03-21 2022-03-02 アカデミア シニカ 合成ペプチド、それを備える薬学的組成物及び血栓塞栓症関連疾患の治療におけるその使用
CN111088206A (zh) * 2020-01-07 2020-05-01 江南大学 一种酶法生产d-泛酸的方法
CN112195143B (zh) * 2020-09-24 2022-10-14 浙江工业大学 一种用于发酵法生产d-泛酸的菌株及发酵法生产d-泛酸的方法
CN118086235A (zh) * 2022-11-28 2024-05-28 宁波酶赛生物工程有限公司 一种合成d-泛解酸的酶催化剂和方法
CN116640700B (zh) * 2023-06-24 2024-05-14 西南大学 一株抑制黄曲霉生长和毒素产生的副干酪乳杆菌f50及其应用
CN117736959B (zh) * 2024-01-26 2024-05-14 湖北大学 运动发酵单胞菌的工程菌株、制备方法及应用

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5514583A (en) 1994-04-15 1996-05-07 Midwest Research Institute Recombinant zymomonas for pentose fermentation
US5712133A (en) 1994-04-15 1998-01-27 Midwest Research Institute Pentose fermentation by recombinant zymomonas
WO1995028476A1 (en) 1994-04-15 1995-10-26 Midwest Research Institute Recombinant zymomonas for pentose fermentation
DE19846499A1 (de) 1998-10-09 2000-04-20 Degussa Verfahren zur Herstellung von Pantothensäure durch Verstärkung von für Ketopantoat-Reduktase kodierenden Nukleotidsequenzen
HU230509B1 (hu) * 1999-09-21 2016-09-28 Basf Aktiengesellschaft Eljárások és mikroorganizmusok panto-vegyületek előállítására
US8232081B2 (en) 1999-09-21 2012-07-31 Basf Se Methods and microorganisms for production of panto-compounds
US7223575B2 (en) 2000-05-01 2007-05-29 Midwest Research Institute Zymomonas pentose-sugar fermenting strains and uses thereof
AU2002316940A1 (en) 2001-07-07 2003-01-29 Degussa Ag Process for the preparation of d-pantothenic acid and/or salts thereof
JP4532116B2 (ja) 2002-01-18 2010-08-25 ノボザイムズ エー/エス アラニン2,3−アミノムターゼ
BRPI0418979A (pt) 2004-07-30 2007-12-11 Cargill Inc 2,3-aminomutases de alanina
BRPI0612937B1 (pt) 2005-04-12 2015-07-07 Du Pont Sistema de processamento de biomassa em bateladas e processo de tratamento de biomassa
US7741119B2 (en) 2006-09-28 2010-06-22 E. I. Du Pont De Nemours And Company Xylitol synthesis mutant of xylose-utilizing zymomonas for ethanol production
US7741084B2 (en) 2006-09-28 2010-06-22 E. I. Du Pont De Nemours And Company Ethanol production using xylitol synthesis mutant of xylose-utilizing zymomonas
US7629156B2 (en) 2006-09-28 2009-12-08 E.I. Du Pont De Nemours And Company Ethanol production in fermentation of mixed sugars containing xylose
ATE554175T1 (de) * 2007-10-30 2012-05-15 Du Pont Zymomonas mit erhöhter ethanolproduktion in einem medium mit konzentrierten zuckern und acetat
WO2009058938A2 (en) 2007-10-30 2009-05-07 E. I. Du Pont De Nemours And Company Process for the production of ethanol from a medium comprising xylose, employing a recombinant zymomonas strain having a reduced hima expression
US7989206B2 (en) 2008-03-27 2011-08-02 E.I. du Pont de Nemours and Company Alliance for Sustainable Energy LLC High expression Zymomonas promoters
JP2011515107A (ja) 2008-03-27 2011-05-19 イー・アイ・デュポン・ドウ・ヌムール・アンド・カンパニー 改善されたキシロース資化能を有するザイモモナス(Zymomonas)
US8247208B2 (en) 2008-12-22 2012-08-21 Alliance For Sustainable Energy Llc Zymomonas with improved xylose utilization in stress conditions
US20110014669A1 (en) * 2009-01-23 2011-01-20 Microbia, Inc. Production of 1,4 Butanediol in a Microorganism

Also Published As

Publication number Publication date
CA2832559A1 (en) 2012-10-26
CN103476927A (zh) 2013-12-25
JP2014511699A (ja) 2014-05-19
US20130078694A1 (en) 2013-03-28
US8765426B2 (en) 2014-07-01
EP2694648A1 (en) 2014-02-12
BR112013025716A2 (pt) 2016-12-13
WO2012145179A1 (en) 2012-10-26

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MK4 Application lapsed section 142(2)(d) - no continuation fee paid for the application