AU2012234218A1 - Bispecific binding molecules binding to Dll4 and Ang2 - Google Patents
Bispecific binding molecules binding to Dll4 and Ang2 Download PDFInfo
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- AU2012234218A1 AU2012234218A1 AU2012234218A AU2012234218A AU2012234218A1 AU 2012234218 A1 AU2012234218 A1 AU 2012234218A1 AU 2012234218 A AU2012234218 A AU 2012234218A AU 2012234218 A AU2012234218 A AU 2012234218A AU 2012234218 A1 AU2012234218 A1 AU 2012234218A1
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Classifications
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- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/22—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against growth factors ; against growth regulators
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- C07K16/46—Hybrid immunoglobulins
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Landscapes
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| PCT/EP2012/055897 WO2012131076A1 (en) | 2011-04-01 | 2012-03-30 | BISPECIFIC BINDING MOLECULES BINDING TO Dll4 AND Ang2 |
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| US9527925B2 (en) | 2011-04-01 | 2016-12-27 | Boehringer Ingelheim International Gmbh | Bispecific binding molecules binding to VEGF and ANG2 |
| MX350248B (es) * | 2012-03-30 | 2017-08-31 | Boehringer Ingelheim Int | Moleculas de union a ang2. |
| EP2900260A1 (en) * | 2012-09-28 | 2015-08-05 | Boehringer Ingelheim International GmbH | Pharmaceutical combinations comprising dual angiopoietin-2 / dll4 binders and anti-vegf agents |
| EA201500370A1 (ru) * | 2012-09-28 | 2015-08-31 | Бёрингер Ингельхайм Интернациональ Гмбх | ФАРМАЦЕВТИЧЕСКИЕ КОМБИНАЦИИ, СОДЕРЖАЩИЕ ДВОЙНЫЕ АНГИОПОЭТИН-2/Dll4 СВЯЗЫВАЮЩИЕ АГЕНТЫ И АНТИ-VEGF-R АГЕНТЫ |
| CN106459960A (zh) | 2014-05-13 | 2017-02-22 | 生物蛋白有限公司 | 条件活性生物蛋白 |
| CN107540747B (zh) * | 2017-08-09 | 2020-01-24 | 苏州大学附属儿童医院 | 抗人dll4单克隆抗体6f12 |
| CN110950967B (zh) * | 2019-12-13 | 2022-05-13 | 山东民康生物科技有限公司 | 抗人血清白蛋白纳米抗体与il-2融合蛋白及制备方法 |
| KR20240048555A (ko) * | 2021-09-10 | 2024-04-15 | 소테르 바이오파마 피티이. 리미티드 | 항 ang2 항체 및 그 제조방법과 응용 |
| CN116444675B (zh) * | 2023-05-11 | 2023-12-22 | 亲和(武汉)生命科技有限责任公司 | 一种Pfu DNA聚合酶纳米抗体及其制备方法和应用 |
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| NZ540194A (en) | 2002-11-08 | 2008-07-31 | Ablynx Nv | Single domain antibodies directed against tumour necrosis factor-alpha and uses therefor |
| EP1558650A2 (en) | 2002-11-08 | 2005-08-03 | Ablynx N.V. | Camelidae antibodies against immunoglobulin e and use thereof for the treatment of allergic disorders |
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2012
- 2012-03-29 US US13/433,354 patent/US20130078247A1/en not_active Abandoned
- 2012-03-30 WO PCT/EP2012/055897 patent/WO2012131076A1/en not_active Ceased
- 2012-03-30 AP AP2013007086A patent/AP2013007086A0/xx unknown
- 2012-03-30 KR KR1020137028119A patent/KR20140016345A/ko not_active Withdrawn
- 2012-03-30 AU AU2012234218A patent/AU2012234218A1/en not_active Abandoned
- 2012-03-30 TW TW101111544A patent/TWI535735B/zh not_active IP Right Cessation
- 2012-03-30 CN CN201280026737.XA patent/CN103596977B/zh not_active Expired - Fee Related
- 2012-03-30 JP JP2014501664A patent/JP2014511682A/ja not_active Ceased
- 2012-03-30 EP EP12711200.1A patent/EP2694545B1/en not_active Not-in-force
- 2012-03-30 AR ARP120101129A patent/AR085919A1/es unknown
- 2012-03-30 SG SG2013070792A patent/SG193557A1/en unknown
- 2012-03-30 PE PE2013002157A patent/PE20141157A1/es not_active Application Discontinuation
- 2012-03-30 TW TW101111526A patent/TWI551612B/zh active
- 2012-03-30 BR BR112013025294A patent/BR112013025294A2/pt not_active IP Right Cessation
- 2012-03-30 MX MX2013011032A patent/MX337115B/es active IP Right Grant
- 2012-03-30 UY UY0001033997A patent/UY33997A/es unknown
- 2012-03-30 CN CN201610374703.XA patent/CN106046167A/zh active Pending
- 2012-03-30 EA EA201301109A patent/EA201301109A1/ru unknown
- 2012-03-30 CA CA2827809A patent/CA2827809A1/en not_active Abandoned
-
2013
- 2013-09-12 CL CL2013002622A patent/CL2013002622A1/es unknown
- 2013-09-26 TN TNP2013000389A patent/TN2013000389A1/fr unknown
- 2013-09-27 MA MA36275A patent/MA35233B1/fr unknown
- 2013-09-27 CO CO13230710A patent/CO6801638A2/es unknown
- 2013-09-30 PH PH12013502031A patent/PH12013502031A1/en unknown
- 2013-10-25 EC ECSP13012996 patent/ECSP13012996A/es unknown
Also Published As
| Publication number | Publication date |
|---|---|
| EP2694545B1 (en) | 2016-08-24 |
| UY33997A (es) | 2012-09-28 |
| TWI551612B (zh) | 2016-10-01 |
| EA201301109A1 (ru) | 2014-08-29 |
| AP2013007086A0 (en) | 2013-08-31 |
| KR20140016345A (ko) | 2014-02-07 |
| US20130078247A1 (en) | 2013-03-28 |
| CN106046167A (zh) | 2016-10-26 |
| TWI535735B (zh) | 2016-06-01 |
| EP2694545A1 (en) | 2014-02-12 |
| TW201302789A (zh) | 2013-01-16 |
| NZ614243A (en) | 2015-04-24 |
| CN103596977A (zh) | 2014-02-19 |
| JP2014511682A (ja) | 2014-05-19 |
| PH12013502031A1 (en) | 2013-12-16 |
| CN103596977B (zh) | 2016-07-06 |
| WO2012131076A1 (en) | 2012-10-04 |
| MX337115B (es) | 2016-02-12 |
| CL2013002622A1 (es) | 2014-02-14 |
| CA2827809A1 (en) | 2012-10-04 |
| ECSP13012996A (es) | 2013-12-31 |
| BR112013025294A2 (pt) | 2017-06-13 |
| CO6801638A2 (es) | 2013-11-29 |
| PE20141157A1 (es) | 2014-09-24 |
| SG193557A1 (en) | 2013-11-29 |
| TN2013000389A1 (en) | 2015-01-20 |
| AR085919A1 (es) | 2013-11-06 |
| MX2013011032A (es) | 2013-12-06 |
| TW201302797A (zh) | 2013-01-16 |
| MA35233B1 (fr) | 2014-07-03 |
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| MK4 | Application lapsed section 142(2)(d) - no continuation fee paid for the application |