AU2011323085B2 - Base modified oligonucleotides - Google Patents
Base modified oligonucleotides Download PDFInfo
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- AU2011323085B2 AU2011323085B2 AU2011323085A AU2011323085A AU2011323085B2 AU 2011323085 B2 AU2011323085 B2 AU 2011323085B2 AU 2011323085 A AU2011323085 A AU 2011323085A AU 2011323085 A AU2011323085 A AU 2011323085A AU 2011323085 B2 AU2011323085 B2 AU 2011323085B2
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- AU
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- Prior art keywords
- oligonucleotide
- base
- nucleotides
- modification
- modified
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| US41067210P | 2010-11-05 | 2010-11-05 | |
| US61/410,672 | 2010-11-05 | ||
| PCT/US2011/059588 WO2012061810A1 (en) | 2010-11-05 | 2011-11-07 | Base modified oligonucleotides |
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| AU2011323085A1 AU2011323085A1 (en) | 2013-03-21 |
| AU2011323085B2 true AU2011323085B2 (en) | 2014-10-30 |
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| EP (1) | EP2635681B8 (https=) |
| JP (1) | JP5995855B2 (https=) |
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| AU (1) | AU2011323085B2 (https=) |
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| WO (1) | WO2012061810A1 (https=) |
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| AU2013202528B2 (en) * | 2010-04-12 | 2015-07-30 | Somalogic Operating Co., Inc. | 5-position modified pyrimidines and their use |
| JP5901610B2 (ja) | 2010-04-12 | 2016-04-13 | ソマロジック・インコーポレーテッド | ５位修飾ピリミジンとその使用 |
| ITRM20110685A1 (it) | 2011-12-23 | 2013-06-24 | Internat Ct For Genetic En Gineering And | Microrna per la rigenerazione cardiaca attraverso l induzione della proliferazione dei miociti cardiaci |
| CN107236735B (zh) * | 2012-06-21 | 2019-11-08 | 米拉根医疗股份有限公司 | 包含锁核酸基序的基于寡核苷酸的抑制剂 |
| DK2970968T3 (en) | 2013-03-15 | 2018-03-05 | Miragen Therapeutics Inc | CONNECTED BICYCLIC Nucleosides |
| KR102290214B1 (ko) | 2013-11-21 | 2021-08-18 | 소마로직, 인크. | 시티딘-5-카르복스아미드 변형된 뉴클레오티드 조성물 및 그와 관련된 방법들 |
| GB201400598D0 (en) | 2014-01-14 | 2014-03-05 | Univ Glasgow | Materials and methods for modulation of tendon healing |
| US20160361340A1 (en) * | 2014-02-11 | 2016-12-15 | Inetitut Pasteur | Treatment of cardiac diseases with modulators of the hippo pathway |
| EP3247716A4 (en) | 2015-01-20 | 2018-10-17 | Miragen Therapeutics, Inc. | Mir-92 inhibitors and uses thereof |
| EP3833762A4 (en) | 2018-08-09 | 2022-09-28 | Verseau Therapeutics, Inc. | Oligonucleotide compositions for targeting ccr2 and csf1r and uses thereof |
| CN110346493B (zh) * | 2019-05-23 | 2021-01-05 | 中国人民解放军军事科学院军事医学研究院 | 检测猕猴血浆中中期因子反义寡核苷酸含量的方法 |
| CN119032177A (zh) * | 2022-06-23 | 2024-11-26 | 安沛治疗有限公司 | 包含喹啉修饰的靶特异性核酸分子 |
| KR20240139119A (ko) * | 2023-03-09 | 2024-09-23 | 주식회사 압타머사이언스 | 티미딘으로부터 개질된 뉴클레오시드의 제조방법 |
| AU2024325721A1 (en) * | 2023-08-17 | 2026-02-26 | Adarx Pharmaceuticals, Inc. | Oligonucleotides containing a ligand at a nucleobase, 2' position, or 3' position |
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| WO2010129950A1 (en) | 2009-05-08 | 2010-11-11 | Board Of Regents, The University Of Texas System | Micro-rna that regulates cardiac remodeling |
| JP5901610B2 (ja) | 2010-04-12 | 2016-04-13 | ソマロジック・インコーポレーテッド | ５位修飾ピリミジンとその使用 |
| KR20140004646A (ko) | 2010-12-15 | 2014-01-13 | 미라젠 세러퓨틱스 | 잠금 뉴클레오티드를 포함하는 마이크로rna 억제제 |
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| US20090137506A1 (en) * | 2007-05-02 | 2009-05-28 | Sirna Therapeutics, Inc. | RNA Interference Mediated Inhibition of Cyclic Nucleotide Type 4 Phosphodiesterase (PDE4B) Gene Expression Using Short Interfering Nucleic Acid (siNA) |
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| US20130296402A1 (en) | 2013-11-07 |
| EP2635681A1 (en) | 2013-09-11 |
| JP2014503192A (ja) | 2014-02-13 |
| CN103492569A (zh) | 2014-01-01 |
| EP2635681A4 (en) | 2015-01-14 |
| AU2011323085A1 (en) | 2013-03-21 |
| CA2817002C (en) | 2019-01-15 |
| CN103492569B (zh) | 2020-04-07 |
| EP2635681B8 (en) | 2017-10-04 |
| WO2012061810A1 (en) | 2012-05-10 |
| JP5995855B2 (ja) | 2016-09-21 |
| US9416360B2 (en) | 2016-08-16 |
| CA2817002A1 (en) | 2012-05-10 |
| EP2635681B1 (en) | 2017-08-23 |
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