AU2011279155B2 - Anti-angiogenic agent and method of using such agent - Google Patents

Anti-angiogenic agent and method of using such agent Download PDF

Info

Publication number
AU2011279155B2
AU2011279155B2 AU2011279155A AU2011279155A AU2011279155B2 AU 2011279155 B2 AU2011279155 B2 AU 2011279155B2 AU 2011279155 A AU2011279155 A AU 2011279155A AU 2011279155 A AU2011279155 A AU 2011279155A AU 2011279155 B2 AU2011279155 B2 AU 2011279155B2
Authority
AU
Australia
Prior art keywords
polypeptide
agent
angiogenic agent
angiogenic
amino acid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
AU2011279155A
Other languages
English (en)
Other versions
AU2011279155A1 (en
Inventor
Zhi-Ren Liu
Yin LU
Jenny J. Yang
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Georgia State University Research Foundation Inc
Original Assignee
Georgia State University Research Foundation Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Georgia State University Research Foundation Inc filed Critical Georgia State University Research Foundation Inc
Publication of AU2011279155A1 publication Critical patent/AU2011279155A1/en
Priority to AU2017201133A priority Critical patent/AU2017201133A1/en
Application granted granted Critical
Publication of AU2011279155B2 publication Critical patent/AU2011279155B2/en
Priority to AU2019202174A priority patent/AU2019202174B2/en
Priority to AU2021201207A priority patent/AU2021201207A1/en
Priority to AU2023202513A priority patent/AU2023202513A1/en
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70503—Immunoglobulin superfamily
    • C07K14/70507—CD2
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/177—Receptors; Cell surface antigens; Cell surface determinants
    • A61K38/1774—Immunoglobulin superfamily (e.g. CD2, CD4, CD8, ICAM molecules, B7 molecules, Fc-receptors, MHC-molecules)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Cell Biology (AREA)
  • Epidemiology (AREA)
  • Diabetes (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Toxicology (AREA)
  • Hematology (AREA)
  • Cardiology (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Endocrinology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Emergency Medicine (AREA)
  • Ophthalmology & Optometry (AREA)
  • Obesity (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicinal Preparation (AREA)
  • Peptides Or Proteins (AREA)
AU2011279155A 2010-07-13 2011-07-13 Anti-angiogenic agent and method of using such agent Active AU2011279155B2 (en)

Priority Applications (4)

Application Number Priority Date Filing Date Title
AU2017201133A AU2017201133A1 (en) 2010-07-13 2017-02-20 Anti-Angiogenic Agent and Method of Using Such Agent
AU2019202174A AU2019202174B2 (en) 2010-07-13 2019-03-29 Anti-angiogenic agent and method of using such agent
AU2021201207A AU2021201207A1 (en) 2010-07-13 2021-02-24 Anti-angiogenic agent and method of using such agent
AU2023202513A AU2023202513A1 (en) 2010-07-13 2023-04-26 Anti-angiogenic agent and method of using such agent

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US36393310P 2010-07-13 2010-07-13
US61/363,933 2010-07-13
PCT/US2011/043907 WO2012009471A1 (en) 2010-07-13 2011-07-13 Anti-angiogenic agent and method of using such agent

Related Child Applications (1)

Application Number Title Priority Date Filing Date
AU2017201133A Division AU2017201133A1 (en) 2010-07-13 2017-02-20 Anti-Angiogenic Agent and Method of Using Such Agent

Publications (2)

Publication Number Publication Date
AU2011279155A1 AU2011279155A1 (en) 2013-01-24
AU2011279155B2 true AU2011279155B2 (en) 2017-03-09

Family

ID=44629339

Family Applications (5)

Application Number Title Priority Date Filing Date
AU2011279155A Active AU2011279155B2 (en) 2010-07-13 2011-07-13 Anti-angiogenic agent and method of using such agent
AU2017201133A Abandoned AU2017201133A1 (en) 2010-07-13 2017-02-20 Anti-Angiogenic Agent and Method of Using Such Agent
AU2019202174A Active AU2019202174B2 (en) 2010-07-13 2019-03-29 Anti-angiogenic agent and method of using such agent
AU2021201207A Abandoned AU2021201207A1 (en) 2010-07-13 2021-02-24 Anti-angiogenic agent and method of using such agent
AU2023202513A Abandoned AU2023202513A1 (en) 2010-07-13 2023-04-26 Anti-angiogenic agent and method of using such agent

Family Applications After (4)

Application Number Title Priority Date Filing Date
AU2017201133A Abandoned AU2017201133A1 (en) 2010-07-13 2017-02-20 Anti-Angiogenic Agent and Method of Using Such Agent
AU2019202174A Active AU2019202174B2 (en) 2010-07-13 2019-03-29 Anti-angiogenic agent and method of using such agent
AU2021201207A Abandoned AU2021201207A1 (en) 2010-07-13 2021-02-24 Anti-angiogenic agent and method of using such agent
AU2023202513A Abandoned AU2023202513A1 (en) 2010-07-13 2023-04-26 Anti-angiogenic agent and method of using such agent

Country Status (12)

Country Link
US (2) US9175063B2 (enExample)
EP (2) EP2593127B1 (enExample)
JP (2) JP6353654B2 (enExample)
CN (1) CN103002904B (enExample)
AU (5) AU2011279155B2 (enExample)
CA (1) CA2804753C (enExample)
DK (1) DK2593127T3 (enExample)
ES (2) ES2674409T3 (enExample)
HU (1) HUE040205T2 (enExample)
PL (1) PL2593127T3 (enExample)
PT (2) PT3381462T (enExample)
WO (1) WO2012009471A1 (enExample)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PT3381462T (pt) * 2010-07-13 2022-07-22 Georgia State Univ Research Foundation Agente antiangiogénico e método de utilização de tal agente
US20180044403A1 (en) * 2015-03-06 2018-02-15 Georgia State University Research Foundation, Inc. Integrin-targeting protein and methods of use thereof
CN110452295B (zh) * 2015-11-10 2022-10-11 孙嘉琳 抗肿瘤蛋白内皮抑素的衍生物
CN108148117A (zh) * 2017-12-26 2018-06-12 张艳雪 一种抗菌肽的蛋白质结构特性及其研究方法

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1990008187A1 (en) * 1989-01-19 1990-07-26 Dana Farber Cancer Institute Soluble two domain cd2 protein
WO2005077018A2 (en) * 2004-02-06 2005-08-25 Astellas Us Llc Methods of treating skin disorders
WO2009146099A2 (en) * 2008-04-02 2009-12-03 Georgia State University Research Foundation, Inc. Contrast agents, methods for preparing contrast agents, and methods of imaging
WO2010028216A2 (en) * 2008-09-08 2010-03-11 Hoffman/Barrett, L.L.C. Porphyrazine optical and dual optical/mr contrast and therapeutic agents

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6162432A (en) * 1991-10-07 2000-12-19 Biogen, Inc. Method of prophylaxis or treatment of antigen presenting cell driven skin conditions using inhibitors of the CD2/LFA-3 interaction
US5595756A (en) * 1993-12-22 1997-01-21 Inex Pharmaceuticals Corporation Liposomal compositions for enhanced retention of bioactive agents
AU2003273299B2 (en) * 2002-09-05 2010-04-01 Medimmune, Llc Methods of preventing or treating cell malignancies by administering CD2 antagonists
US9339559B2 (en) * 2005-09-09 2016-05-17 Georgia State University Research Foundation, Inc. Targeted contrast agents and methods for targeting contrast agents
PT3381462T (pt) * 2010-07-13 2022-07-22 Georgia State Univ Research Foundation Agente antiangiogénico e método de utilização de tal agente

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1990008187A1 (en) * 1989-01-19 1990-07-26 Dana Farber Cancer Institute Soluble two domain cd2 protein
WO2005077018A2 (en) * 2004-02-06 2005-08-25 Astellas Us Llc Methods of treating skin disorders
WO2009146099A2 (en) * 2008-04-02 2009-12-03 Georgia State University Research Foundation, Inc. Contrast agents, methods for preparing contrast agents, and methods of imaging
WO2010028216A2 (en) * 2008-09-08 2010-03-11 Hoffman/Barrett, L.L.C. Porphyrazine optical and dual optical/mr contrast and therapeutic agents

Non-Patent Citations (8)

* Cited by examiner, † Cited by third party
Title
BODIAN, D. L. ET. AL. Structure, 1994, 2(8), 755-766 *
DRISCOLL, P. C. ET. AL. Nature, 1991, 353, 762-765 *
FERRARA, N. ET. AL. Nature Reviews/Drug Discovery, 2004, 3, 391-400 *
GARCIA, A. A. ET. AL. Journal of Clinical Oncology, 2008, 26, 76-82 *
KOZIN, S. V. ET. AL. Cancer Research, 2001, 61, 39-44 *
MURRAY, A. J. ET. AL. Proceedings of National Academy of Sciences, USA, 1995, 92, 7337-7341 *
SEED, B. ET. AL. Proceedings of National Academy of Sciences, USA, 1987, 84, 3365-3369 *
WITHKA, J. M. ET. AL. Structure, 1993, 1, 69-81 *

Also Published As

Publication number Publication date
JP6353654B2 (ja) 2018-07-04
AU2019202174B2 (en) 2020-11-26
WO2012009471A1 (en) 2012-01-19
JP2013534538A (ja) 2013-09-05
EP2593127B1 (en) 2018-05-30
ES2923430T3 (es) 2022-09-27
PL2593127T3 (pl) 2018-11-30
HUE040205T2 (hu) 2019-02-28
CA2804753A1 (en) 2012-01-19
AU2017201133A1 (en) 2017-03-09
EP2593127A1 (en) 2013-05-22
CA2804753C (en) 2021-05-25
DK2593127T3 (en) 2018-07-02
AU2019202174A1 (en) 2019-04-18
US20160090408A1 (en) 2016-03-31
AU2021201207A1 (en) 2021-03-11
AU2023202513A1 (en) 2023-05-11
JP2016175913A (ja) 2016-10-06
US20130281357A1 (en) 2013-10-24
EP3381462A1 (en) 2018-10-03
CN103002904B (zh) 2017-01-18
US9175063B2 (en) 2015-11-03
PT3381462T (pt) 2022-07-22
AU2011279155A1 (en) 2013-01-24
ES2674409T3 (es) 2018-06-29
CN103002904A (zh) 2013-03-27
EP3381462B1 (en) 2022-06-08
PT2593127T (pt) 2018-07-06
US11578114B2 (en) 2023-02-14

Similar Documents

Publication Publication Date Title
AU2023202513A1 (en) Anti-angiogenic agent and method of using such agent
WO2003097835A2 (en) Pharmaceutical compositions for the treatment of cancer
US20040156828A1 (en) Adeno-associated virus mediated B7.1 vaccination synergizes with angiostatin to eradicate disseminated liver metastatic cancers
US20210008173A1 (en) Endostatin peptides for the treatment of tumors, fibrosis and acute lung injury
US12410230B2 (en) Anti-angiogenic agent and methods of using such agent
US20100196389A1 (en) Methods of using corticotropin-releasing factor for the use of the treatment of cancer
WO2024173546A2 (en) Anti-angiogenic agent and methods of using such agent
EP4665378A2 (en) Anti-angiogenic agent and methods of using such agent
US20120183536A1 (en) Methods of using corticotropin-releasing factor for the treatment of cancer
US20240390465A1 (en) Endostatin Peptides for the Treatment of Tumors, Fibrosis and Acute Lung Injury
WO2022198027A1 (en) DNA-ENCODED BISPECIFIC ANTIBODIES TARGETING IL13Rα2 AND METHODS OF USE IN CANCER THERAPEUTICS
US20230241167A1 (en) Use of Caveolin-1 Scaffolding Domain Peptides for Treating Disease and Disorders
WO2010057962A2 (en) Crf conjugates with extended half-lives

Legal Events

Date Code Title Description
FGA Letters patent sealed or granted (standard patent)