AU2011248175A1 - Aza-Indole derivatives useful as modulators of FAAH - Google Patents

Aza-Indole derivatives useful as modulators of FAAH Download PDF

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Publication number
AU2011248175A1
AU2011248175A1 AU2011248175A AU2011248175A AU2011248175A1 AU 2011248175 A1 AU2011248175 A1 AU 2011248175A1 AU 2011248175 A AU2011248175 A AU 2011248175A AU 2011248175 A AU2011248175 A AU 2011248175A AU 2011248175 A1 AU2011248175 A1 AU 2011248175A1
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AU
Australia
Prior art keywords
pyrrolo
chlorophenyl
4alkyl
hydroxyl
halo
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2011248175A
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English (en)
Inventor
Constantine Kreatsoulas
Keith P. Moore
Philippe G. Nantermet
Rachel Anne Storr
Laura Vassallo
Abbas M. Walji
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck Sharp and Dohme LLC
Original Assignee
Merck Sharp and Dohme Ltd
Merck Sharp and Dohme LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck Sharp and Dohme Ltd, Merck Sharp and Dohme LLC filed Critical Merck Sharp and Dohme Ltd
Publication of AU2011248175A1 publication Critical patent/AU2011248175A1/en
Abandoned legal-status Critical Current

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
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    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00

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  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
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  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
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  • Neurosurgery (AREA)
  • Pain & Pain Management (AREA)
  • Psychiatry (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Addiction (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Obesity (AREA)
  • Urology & Nephrology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Rheumatology (AREA)
  • Communicable Diseases (AREA)
  • Cardiology (AREA)
  • Hospice & Palliative Care (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Psychology (AREA)
  • Oncology (AREA)
  • Reproductive Health (AREA)
  • Anesthesiology (AREA)
  • Child & Adolescent Psychology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Pregnancy & Childbirth (AREA)
AU2011248175A 2010-05-06 2011-05-04 Aza-Indole derivatives useful as modulators of FAAH Abandoned AU2011248175A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US33197410P 2010-05-06 2010-05-06
US61/331,974 2010-05-06
PCT/US2011/035091 WO2011140164A1 (en) 2010-05-06 2011-05-04 Aza-indole derivatives useful as modulators of faah

Publications (1)

Publication Number Publication Date
AU2011248175A1 true AU2011248175A1 (en) 2012-10-25

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ID=44904047

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2011248175A Abandoned AU2011248175A1 (en) 2010-05-06 2011-05-04 Aza-Indole derivatives useful as modulators of FAAH

Country Status (8)

Country Link
US (1) US20130059850A1 (enExample)
EP (1) EP2566481A4 (enExample)
JP (1) JP2013525490A (enExample)
CN (1) CN102917707A (enExample)
AU (1) AU2011248175A1 (enExample)
BR (1) BR112012028055A2 (enExample)
CA (1) CA2797281A1 (enExample)
WO (1) WO2011140164A1 (enExample)

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GB201411236D0 (en) * 2014-06-25 2014-08-06 Takeda Pharmaceutical Novel compounds
DK3362449T3 (da) * 2015-10-13 2021-07-19 Inst Nat Sante Rech Med Sibirilin-derivater til anvendelse til at forebygge og/eller behandle lidelser associeret med cellulær nekroptose
CN110352192B (zh) * 2016-09-16 2023-03-24 住友化学株式会社 杂环化合物及含有其的有害节肢动物防治剂
CN109589325B (zh) * 2019-02-19 2019-11-26 牡丹江医学院 一种用于治疗肠炎的药物组合物及其制备方法
US12358875B2 (en) * 2019-06-17 2025-07-15 Ucb Pharma Gmbh N-(phenyl)-indole-3-sulfonamide derivatives and related compounds as GPR17 modulators for treating CNS disorders such as multiple sclerosis
CN111743864B (zh) * 2020-08-05 2022-04-01 牡丹江医学院 一种体育外伤喷雾剂及其制备方法
CN112159423A (zh) * 2020-11-03 2021-01-01 凯美克(上海)医药科技有限公司 1H-吡咯并[2,3-b]吡啶-2-硼酸频哪醇酯的合成方法
JP2024506530A (ja) * 2021-01-25 2024-02-14 シービーライフ フェロトーシス制御性細胞死の阻害剤としてのインドール、６－および７－アザインドール誘導体の使用

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FR2705346B1 (fr) * 1993-05-18 1995-08-11 Union Pharma Scient Appl Nouveaux dérivés de pipéridinyl thio indole, leurs procédés de préparation, compositions pharmaceutiques les contenant, utiles notamment comme antalgiques .
BR0307406A (pt) * 2002-02-01 2004-12-28 Hoffmann La Roche Indóis substituìdos como agonistas alfa-1
UA78999C2 (en) * 2002-06-04 2007-05-10 Wyeth Corp 1-(aminoalkyl)-3-sulfonylazaindoles as ligands of 5-hydroxytryptamine-6
TW200403243A (en) * 2002-07-18 2004-03-01 Wyeth Corp 1-Heterocyclylalkyl-3-sulfonylazaindole or-azaindazole derivatives as 5-hydroxytryptamine-6 ligands
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AU2004213375A1 (en) * 2003-02-14 2004-09-02 Wyeth Heterocyclyl-3-sulfonylazaindole or -azaindazole derivatives as 5-Hydroxytryptamine-6 ligands
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Publication number Publication date
JP2013525490A (ja) 2013-06-20
EP2566481A4 (en) 2014-01-22
CA2797281A1 (en) 2011-11-10
CN102917707A (zh) 2013-02-06
EP2566481A1 (en) 2013-03-13
WO2011140164A1 (en) 2011-11-10
BR112012028055A2 (pt) 2019-09-24
US20130059850A1 (en) 2013-03-07

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