AU2011203977B2 - Method to use gene expression to determine likelihood of clinical outcome of renal cancer - Google Patents

Method to use gene expression to determine likelihood of clinical outcome of renal cancer Download PDF

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AU2011203977B2
AU2011203977B2 AU2011203977A AU2011203977A AU2011203977B2 AU 2011203977 B2 AU2011203977 B2 AU 2011203977B2 AU 2011203977 A AU2011203977 A AU 2011203977A AU 2011203977 A AU2011203977 A AU 2011203977A AU 2011203977 B2 AU2011203977 B2 AU 2011203977B2
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gene
expression level
ppap2b
tumor
expression
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AU2011203977A1 (en
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Frederick L. Baehner
Joffre Baker
Wayne Cowens
Audrey Goddard
Michael C. Kiefer
Dejan Knezevic
Tara Maddala
Steven Shak
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Genomic Health Inc
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Priority to AU2017216545A priority patent/AU2017216545B2/en
Priority to AU2019268079A priority patent/AU2019268079B2/en
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57407—Specifically defined cancers
    • G01N33/57438—Specifically defined cancers of liver, pancreas or kidney
    • G—PHYSICS
    • G06—COMPUTING OR CALCULATING; COUNTING
    • G06N—COMPUTING ARRANGEMENTS BASED ON SPECIFIC COMPUTATIONAL MODELS
    • G06N7/00—Computing arrangements based on specific mathematical models
    • G06N7/01—Probabilistic graphical models, e.g. probabilistic networks
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B25/00—ICT specially adapted for hybridisation; ICT specially adapted for gene or protein expression
    • G16B25/10—Gene or protein expression profiling; Expression-ratio estimation or normalisation
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B99/00—Subject matter not provided for in other groups of this subclass
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
    • G16H50/00—ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics
    • G16H50/20—ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for computer-aided diagnosis, e.g. based on medical expert systems
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/112—Disease subtyping, staging or classification
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/118—Prognosis of disease development
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/158—Expression markers

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  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Theoretical Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Genetics & Genomics (AREA)
  • Medical Informatics (AREA)
  • Urology & Nephrology (AREA)
  • Pathology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Hematology (AREA)
  • Evolutionary Biology (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Microbiology (AREA)
  • Hospice & Palliative Care (AREA)
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  • Biophysics (AREA)
  • General Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Data Mining & Analysis (AREA)
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  • Food Science & Technology (AREA)
  • Cell Biology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Computational Mathematics (AREA)
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AU2011203977A 2010-01-11 2011-01-07 Method to use gene expression to determine likelihood of clinical outcome of renal cancer Active AU2011203977B2 (en)

Priority Applications (3)

Application Number Priority Date Filing Date Title
AU2015202116A AU2015202116B2 (en) 2010-01-11 2015-04-24 Method to use gene expression to determine likelihood of clinical outcome of renal cancer
AU2017216545A AU2017216545B2 (en) 2010-01-11 2017-08-17 Method to use gene expression to determine likelihood of clinical outcome of renal cancer
AU2019268079A AU2019268079B2 (en) 2010-01-11 2019-11-19 Method to use gene expression to determine likelihood of clinical outcome of renal cancer

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US29403810P 2010-01-11 2010-01-11
US61/294,038 2010-01-11
US34623010P 2010-05-19 2010-05-19
US61/346,230 2010-05-19
PCT/US2011/020596 WO2011085263A2 (en) 2010-01-11 2011-01-07 Method to use gene expression to determine likelihood of clinical outcome of renal cancer

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AU2011203977A1 AU2011203977A1 (en) 2012-06-21
AU2011203977B2 true AU2011203977B2 (en) 2015-02-05

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EP (5) EP3561078A1 (cg-RX-API-DMAC7.html)
JP (5) JP6286124B2 (cg-RX-API-DMAC7.html)
AU (1) AU2011203977B2 (cg-RX-API-DMAC7.html)
CA (3) CA3128103C (cg-RX-API-DMAC7.html)
DK (1) DK3178944T3 (cg-RX-API-DMAC7.html)
ES (2) ES3027507T3 (cg-RX-API-DMAC7.html)
IL (6) IL219978A (cg-RX-API-DMAC7.html)
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NZ (4) NZ705645A (cg-RX-API-DMAC7.html)
SG (1) SG181806A1 (cg-RX-API-DMAC7.html)
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US20210166790A1 (en) 2021-06-03
US11776664B2 (en) 2023-10-03
EP3831964A2 (en) 2021-06-09
IL219978A0 (en) 2012-07-31
JP2021177761A (ja) 2021-11-18
US20240096451A1 (en) 2024-03-21
MX2020009704A (es) 2020-10-07
EP3029155A2 (en) 2016-06-08
MX375138B (es) 2025-03-06
EP2524055A2 (en) 2012-11-21
NZ617003A (en) 2015-04-24
IL219978A (en) 2017-04-30
SG181806A1 (en) 2012-07-30
JP6546214B2 (ja) 2019-07-17
NZ705645A (en) 2016-05-27
EP3831964B1 (en) 2025-04-16
EP3178944A3 (en) 2017-09-13
JP2019162150A (ja) 2019-09-26
JP7307602B2 (ja) 2023-07-12
NZ600268A (en) 2014-08-29
IL251635A0 (en) 2017-06-29
MX341866B (es) 2016-09-06
EP3178944A2 (en) 2017-06-14
EP3178944B1 (en) 2019-05-15
US12412642B2 (en) 2025-09-09
IL262100B (en) 2019-11-28
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