AU2010310518A1 - mGluR4 allosteric potentiators, compositions, and methods of treating neurological dysfunction - Google Patents

mGluR4 allosteric potentiators, compositions, and methods of treating neurological dysfunction Download PDF

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Publication number
AU2010310518A1
AU2010310518A1 AU2010310518A AU2010310518A AU2010310518A1 AU 2010310518 A1 AU2010310518 A1 AU 2010310518A1 AU 2010310518 A AU2010310518 A AU 2010310518A AU 2010310518 A AU2010310518 A AU 2010310518A AU 2010310518 A1 AU2010310518 A1 AU 2010310518A1
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optionally substituted
cycloalkyl
membered ring
ring containing
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P. Jeffrey Conn
Rocco D. Gogliotti
Corey R. Hopkins
Craig W. Lindsley
Colleen M. Niswender
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Vanderbilt University
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Vanderbilt University
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    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
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AU2010310518A 2009-10-22 2010-10-22 mGluR4 allosteric potentiators, compositions, and methods of treating neurological dysfunction Abandoned AU2010310518A1 (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US25406209P 2009-10-22 2009-10-22
US61/254,062 2009-10-22
US29272510P 2010-01-06 2010-01-06
US61/292,725 2010-01-06
PCT/US2010/053825 WO2011050305A1 (en) 2009-10-22 2010-10-22 Mglur4 allosteric potentiators, compositions, and methods of treating neurological dysfunction

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AU2010310518A1 true AU2010310518A1 (en) 2012-06-07

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JP2012516355A (ja) 2009-01-28 2012-07-19 ヴァンダービルト ユニバーシティー ｍＧＬｕＲ４アロステリック増強剤としての置換された１，１，３，３−テトラオキシドベンゾ［ｄ］［１，３，２］ジチアゾール、組成物、および神経機能不全を治療する方法
US8759377B2 (en) 2009-11-23 2014-06-24 Vanderbilt University Substituted dioxopiperidines and dioxopyrrolidines as MGLUR4 allosteric potentiators, compositions, and methods of treating neurological dysfunction
CN102933572B (zh) 2010-04-07 2015-01-07 霍夫曼-拉罗奇有限公司 吡唑-4-基-杂环基-甲酰胺化合物及其使用方法
BR112014007203A2 (pt) 2011-09-27 2017-06-13 F.Hoffmann-La Roche Ag composto, composição farmacêutica, método de tratamento, utilização de um composto, conjunto e invenção
EP2853532B1 (en) 2013-09-28 2020-12-09 Instytut Farmakologii Polskiej Akademii Nauk 1,2,4-oxadiazole derivatives as allosteric modulators of metabotropic glutamate receptors belonging to group III
US10221172B2 (en) 2015-01-13 2019-03-05 Vanderbilt University Benzothiazole and benzisothiazole-substituted compounds as mGluR4 allosteric potentiators, compositions, and methods of treating neurological dysfunction
WO2016123629A1 (en) 2015-01-30 2016-08-04 Vanderbilt University Indazole and azaindazole substituted compounds as mglur4 allosteric potentiators, compositions, and methods of treating neurological dysfunction
WO2016123627A1 (en) 2015-01-30 2016-08-04 Vanderbilt University Isoquiniline and napthalene-substituted compounds as mglur4 allosteric potentiators, compounds, and methods of treating neurological dysfunction
US9987242B2 (en) 2015-05-05 2018-06-05 Northwestern University Treatment of Levodopa-induced Dyskinesias
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