AU2010296994B2 - Novel peptides isolated from spider venom, and uses thereof - Google Patents

Novel peptides isolated from spider venom, and uses thereof Download PDF

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Publication number
AU2010296994B2
AU2010296994B2 AU2010296994A AU2010296994A AU2010296994B2 AU 2010296994 B2 AU2010296994 B2 AU 2010296994B2 AU 2010296994 A AU2010296994 A AU 2010296994A AU 2010296994 A AU2010296994 A AU 2010296994A AU 2010296994 B2 AU2010296994 B2 AU 2010296994B2
Authority
AU
Australia
Prior art keywords
peptide
pain
seq
peptides
venom
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
AU2010296994A
Other languages
English (en)
Other versions
AU2010296994A1 (en
Inventor
Nissim Bajayo
Ronit Simcha Cherki
Ela Kolb
Yael Langut
Alon Meir
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Alomone Preclinical Ltd
Original Assignee
Alomone Preclinical Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Alomone Preclinical Ltd filed Critical Alomone Preclinical Ltd
Publication of AU2010296994A1 publication Critical patent/AU2010296994A1/en
Application granted granted Critical
Publication of AU2010296994B2 publication Critical patent/AU2010296994B2/en
Ceased legal-status Critical Current
Anticipated expiration legal-status Critical

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/43504—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates
    • C07K14/43513—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates from arachnidae
    • C07K14/43518—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates from arachnidae from spiders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/06—Antimigraine agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Insects & Arthropods (AREA)
  • Pain & Pain Management (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Toxicology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Rheumatology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
AU2010296994A 2009-09-15 2010-09-13 Novel peptides isolated from spider venom, and uses thereof Ceased AU2010296994B2 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US27233609P 2009-09-15 2009-09-15
US61/272,336 2009-09-15
PCT/IB2010/002275 WO2011033358A2 (en) 2009-09-15 2010-09-13 Novel peptides isolated from spider venom, and uses thereof

Publications (2)

Publication Number Publication Date
AU2010296994A1 AU2010296994A1 (en) 2012-04-19
AU2010296994B2 true AU2010296994B2 (en) 2013-09-19

Family

ID=43731158

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2010296994A Ceased AU2010296994B2 (en) 2009-09-15 2010-09-13 Novel peptides isolated from spider venom, and uses thereof

Country Status (12)

Country Link
US (1) US8399026B2 (enExample)
EP (1) EP2504023B1 (enExample)
JP (1) JP5555891B2 (enExample)
CN (1) CN102573884B (enExample)
AR (1) AR078374A1 (enExample)
AU (1) AU2010296994B2 (enExample)
BR (1) BR112012005860A2 (enExample)
CA (1) CA2774350A1 (enExample)
IL (1) IL218382A0 (enExample)
MX (1) MX2012003078A (enExample)
SG (1) SG179101A1 (enExample)
WO (1) WO2011033358A2 (enExample)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SG10201601789TA (en) * 2011-03-16 2016-04-28 Amgen Inc Potent And Selective Inhibitors Of Nav1.3 And Nav1.7
WO2013026105A1 (en) * 2011-08-24 2013-02-28 The University Of Queensland Pest-controlling agents isolated from spider venom and uses thereof
EP2852397B1 (en) 2012-05-18 2022-02-16 Janssen Biotech, Inc. Huwentoxin-iv variants and methods of use
US9102751B2 (en) 2012-05-18 2015-08-11 Janssen Biotech, Inc. Huwentoxin-IV variants and methods of use
US10414808B2 (en) 2012-05-18 2019-09-17 Janssen Biotech, Inc. Huwentoxin-IV variants and methods of use
JP6086378B2 (ja) * 2012-11-30 2017-03-01 国立大学法人お茶の水女子大学 組み換えヒト膵臓リパーゼの調製方法
US9636418B2 (en) 2013-03-12 2017-05-02 Amgen Inc. Potent and selective inhibitors of NAV1.7
US10344060B2 (en) 2013-03-12 2019-07-09 Amgen Inc. Potent and selective inhibitors of Nav1.7
ES2841173T3 (es) 2013-10-03 2021-07-07 Janssen Biotech Inc Variantes de Protoxina-II y métodos de uso
GB201410108D0 (en) * 2014-06-06 2014-07-23 Univ Manchester Peptides, and methods and apparatus utilising same
MA41642A (fr) 2015-03-03 2018-01-09 Janssen Biotech Inc Variants de protoxine ii et méthodes d'utilisation
MX2017012654A (es) 2015-04-02 2018-01-09 Janssen Biotech Inc Variantes de protoxina-ii y metodos de uso.
CL2016002890A1 (es) * 2016-11-14 2017-06-30 Univ Antofagasta Peptidos con actividad antimicrobiana
CN107141343A (zh) * 2017-06-01 2017-09-08 长沙沁才生物科技有限公司 一种活性多肽spkp‑xi的制备方法
CN107141344A (zh) * 2017-06-01 2017-09-08 长沙沁才生物科技有限公司 一种新型天然活性多肽spkp‑xi
CN107163124A (zh) * 2017-06-22 2017-09-15 长沙沁才生物科技有限公司 SPNP‑IX在制备Nav1.3通道抑制剂中的应用
CN107496904B (zh) * 2017-09-21 2020-03-17 中南大学 多肽Lycosin-Ⅰ在制备抗炎和抗弓形虫药物中的应用
CN108047323B (zh) * 2017-12-20 2022-04-12 深圳羽众医药科技有限公司 一种固相片段法合成GpTx-1及其类似物和合成方法
US20230374084A1 (en) * 2020-09-23 2023-11-23 Aldevron, Llc Potent and selective inhibitors of nav1.7

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US4450150A (en) 1973-05-17 1984-05-22 Arthur D. Little, Inc. Biodegradable, implantable drug delivery depots, and method for preparing and using the same
US4675381A (en) 1983-07-01 1987-06-23 Battelle Memorial Institute Biodegradable polypeptide and its use for the gradual release of drugs
US5417986A (en) 1984-03-16 1995-05-23 The United States Of America As Represented By The Secretary Of The Army Vaccines against diseases caused by enteropathogenic organisms using antigens encapsulated within biodegradable-biocompatible microspheres
US5776896A (en) * 1996-01-03 1998-07-07 Zeneca Limited Analgesic peptides from venom of grammostola spatulata and use thereof
CN1133461C (zh) * 2000-04-11 2004-01-07 厦门北大之路生物工程有限公司 虎纹捕鸟蜘蛛毒素提取物在制备镇痛药物中的应用
JP2004537253A (ja) * 2000-07-21 2004-12-16 ユニバーシティ・オブ・ユタ・リサーチ・ファウンデーション ミュー−コノペプチド
EP1578787B1 (en) * 2002-12-02 2012-11-14 Xenome Ltd Novel chi-conotoxin peptides (-ii)

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
BOSMANS, F., et al., "Four Novel Tarantula Toxins as Selective Modulators of Voltage-Gated Sodium Channel Subtypes," Molecular Pharmacology, 2006, Vol. 69, No. 2, pages 419-429. *
PARK, S. P., et al., "A tarantula spider toxin, GsMTx4, reduces mechanical and neuropathic pain," Pain, 2008, Vol. 137, pages 208-217. *
XIAO, Y., et al., The Journal of Biological Chemistry, 2008, Vol. 283, No. 40, pages 27300-27313. *

Also Published As

Publication number Publication date
AU2010296994A1 (en) 2012-04-19
US8399026B2 (en) 2013-03-19
JP2013504318A (ja) 2013-02-07
SG179101A1 (en) 2012-05-30
MX2012003078A (es) 2012-08-03
IL218382A0 (en) 2012-04-30
WO2011033358A2 (en) 2011-03-24
BR112012005860A2 (pt) 2017-01-31
EP2504023A4 (en) 2013-04-10
EP2504023A2 (en) 2012-10-03
CN102573884A (zh) 2012-07-11
JP5555891B2 (ja) 2014-07-23
WO2011033358A3 (en) 2011-07-14
AR078374A1 (es) 2011-11-02
CN102573884B (zh) 2015-01-14
CA2774350A1 (en) 2011-03-24
EP2504023B1 (en) 2015-07-15
US20110065647A1 (en) 2011-03-17

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FGA Letters patent sealed or granted (standard patent)
MK14 Patent ceased section 143(a) (annual fees not paid) or expired