AR078374A1 - Peptidos aislados de veneno de arana y sus usos como potentes y selectivos bloqueadores del canal ionico - Google Patents
Peptidos aislados de veneno de arana y sus usos como potentes y selectivos bloqueadores del canal ionicoInfo
- Publication number
- AR078374A1 AR078374A1 ARP100103359A ARP100103359A AR078374A1 AR 078374 A1 AR078374 A1 AR 078374A1 AR P100103359 A ARP100103359 A AR P100103359A AR P100103359 A ARP100103359 A AR P100103359A AR 078374 A1 AR078374 A1 AR 078374A1
- Authority
- AR
- Argentina
- Prior art keywords
- seq
- arana
- poison
- powerful
- isolated peptides
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/43504—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates
- C07K14/43513—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates from arachnidae
- C07K14/43518—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates from arachnidae from spiders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Insects & Arthropods (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Pain & Pain Management (AREA)
- Gastroenterology & Hepatology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Toxicology (AREA)
- Zoology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Rheumatology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Abstract
El objeto actualmente descrito se refiere a péptidos de veneno de arana aislados y, a una composicion farmacéutica y a métodos para el tratamiento del dolor. Reivindicacion 1: Un péptido aislado que comprende una secuencia de aminoácidos seleccionada del grupo que consiste en SEQ ID Ns:1, SEQ ID Ns:2, SEQ ID Ns:3, SEQ ID Ns:4, SEQ ID Ns:5 y una de sus formas amidadas en C-terminal.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US27233609P | 2009-09-15 | 2009-09-15 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AR078374A1 true AR078374A1 (es) | 2011-11-02 |
Family
ID=43731158
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ARP100103359A AR078374A1 (es) | 2009-09-15 | 2010-09-15 | Peptidos aislados de veneno de arana y sus usos como potentes y selectivos bloqueadores del canal ionico |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US8399026B2 (es) |
| EP (1) | EP2504023B1 (es) |
| JP (1) | JP5555891B2 (es) |
| CN (1) | CN102573884B (es) |
| AR (1) | AR078374A1 (es) |
| AU (1) | AU2010296994B2 (es) |
| BR (1) | BR112012005860A2 (es) |
| CA (1) | CA2774350A1 (es) |
| IL (1) | IL218382A0 (es) |
| MX (1) | MX2012003078A (es) |
| SG (1) | SG179101A1 (es) |
| WO (1) | WO2011033358A2 (es) |
Families Citing this family (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| UY33959A (es) * | 2011-03-16 | 2012-09-28 | Amgen Inc | INHIBIDORES POTENTES Y SELECTIVOS DE NaV1.3 Y NaV1.7 |
| AU2012300197B2 (en) * | 2011-08-24 | 2018-01-18 | The University Of Queensland | Pest-controlling agents isolated from spider venom and uses thereof |
| JP6771282B2 (ja) | 2012-05-18 | 2020-10-21 | ヤンセン バイオテツク，インコーポレーテツド | フエントキシンｉｖ変異体及びその使用方法 |
| US10414808B2 (en) | 2012-05-18 | 2019-09-17 | Janssen Biotech, Inc. | Huwentoxin-IV variants and methods of use |
| US9102751B2 (en) | 2012-05-18 | 2015-08-11 | Janssen Biotech, Inc. | Huwentoxin-IV variants and methods of use |
| JP6086378B2 (ja) * | 2012-11-30 | 2017-03-01 | 国立大学法人お茶の水女子大学 | 組み換えヒト膵臓リパーゼの調製方法 |
| AR096927A1 (es) | 2013-03-12 | 2016-02-10 | Amgen Inc | INHIBIDORES POTENTES Y SELECTIVOS DE NaV1.7 |
| EP2970408B1 (en) | 2013-03-12 | 2018-01-10 | Amgen Inc. | Potent and selective inhibitors of nav1.7 |
| AU2014329454B2 (en) | 2013-10-03 | 2019-01-17 | Janssen Biotech, Inc. | Protoxin-II variants and methods of use |
| GB201410108D0 (en) * | 2014-06-06 | 2014-07-23 | Univ Manchester | Peptides, and methods and apparatus utilising same |
| MA41642A (fr) | 2015-03-03 | 2018-01-09 | Janssen Biotech Inc | Variants de protoxine ii et méthodes d'utilisation |
| BR112017020896A2 (pt) | 2015-04-02 | 2018-07-10 | Janssen Biotech Inc | variantes de protoxina-ii e métodos de uso |
| CL2016002890A1 (es) * | 2016-11-14 | 2017-06-30 | Univ Antofagasta | Peptidos con actividad antimicrobiana |
| CN107141344A (zh) * | 2017-06-01 | 2017-09-08 | 长沙沁才生物科技有限公司 | 一种新型天然活性多肽spkp‑xi |
| CN107141343A (zh) * | 2017-06-01 | 2017-09-08 | 长沙沁才生物科技有限公司 | 一种活性多肽spkp‑xi的制备方法 |
| CN107163124A (zh) * | 2017-06-22 | 2017-09-15 | 长沙沁才生物科技有限公司 | SPNP‑IX在制备Nav1.3通道抑制剂中的应用 |
| CN107496904B (zh) * | 2017-09-21 | 2020-03-17 | 中南大学 | 多肽Lycosin-Ⅰ在制备抗炎和抗弓形虫药物中的应用 |
| CN108047323B (zh) * | 2017-12-20 | 2022-04-12 | 深圳羽众医药科技有限公司 | 一种固相片段法合成GpTx-1及其类似物和合成方法 |
| US20230374084A1 (en) * | 2020-09-23 | 2023-11-23 | Aldevron, Llc | Potent and selective inhibitors of nav1.7 |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4450150A (en) | 1973-05-17 | 1984-05-22 | Arthur D. Little, Inc. | Biodegradable, implantable drug delivery depots, and method for preparing and using the same |
| JPS60501759A (ja) | 1983-07-01 | 1985-10-17 | バテル メモリアル インステイチユ−ト | 生物分解性ポリペプチド及び薬剤の緩慢な放出のためのその使用 |
| US5417986A (en) | 1984-03-16 | 1995-05-23 | The United States Of America As Represented By The Secretary Of The Army | Vaccines against diseases caused by enteropathogenic organisms using antigens encapsulated within biodegradable-biocompatible microspheres |
| US5776896A (en) * | 1996-01-03 | 1998-07-07 | Zeneca Limited | Analgesic peptides from venom of grammostola spatulata and use thereof |
| CN1133461C (zh) * | 2000-04-11 | 2004-01-07 | 厦门北大之路生物工程有限公司 | 虎纹捕鸟蜘蛛毒素提取物在制备镇痛药物中的应用 |
| US6727226B2 (en) * | 2000-07-21 | 2004-04-27 | University Of Utah Research Foundation | Mu-conopeptides |
| EP2386566A3 (en) * | 2002-12-02 | 2012-02-15 | Xenome Ltd | Chi-conotoxin peptides (II) |
-
2010
- 2010-09-13 BR BR112012005860A patent/BR112012005860A2/pt not_active IP Right Cessation
- 2010-09-13 MX MX2012003078A patent/MX2012003078A/es active IP Right Grant
- 2010-09-13 WO PCT/IB2010/002275 patent/WO2011033358A2/en active Application Filing
- 2010-09-13 SG SG2012017398A patent/SG179101A1/en unknown
- 2010-09-13 EP EP10816761.0A patent/EP2504023B1/en not_active Not-in-force
- 2010-09-13 JP JP2012528465A patent/JP5555891B2/ja not_active Expired - Fee Related
- 2010-09-13 CA CA2774350A patent/CA2774350A1/en not_active Abandoned
- 2010-09-13 AU AU2010296994A patent/AU2010296994B2/en not_active Ceased
- 2010-09-13 CN CN201080041208.8A patent/CN102573884B/zh not_active Expired - Fee Related
- 2010-09-14 US US12/881,269 patent/US8399026B2/en active Active
- 2010-09-15 AR ARP100103359A patent/AR078374A1/es unknown
-
2012
- 2012-02-28 IL IL218382A patent/IL218382A0/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| EP2504023A4 (en) | 2013-04-10 |
| CA2774350A1 (en) | 2011-03-24 |
| IL218382A0 (en) | 2012-04-30 |
| MX2012003078A (es) | 2012-08-03 |
| US20110065647A1 (en) | 2011-03-17 |
| CN102573884B (zh) | 2015-01-14 |
| BR112012005860A2 (pt) | 2017-01-31 |
| AU2010296994B2 (en) | 2013-09-19 |
| US8399026B2 (en) | 2013-03-19 |
| SG179101A1 (en) | 2012-05-30 |
| WO2011033358A2 (en) | 2011-03-24 |
| EP2504023B1 (en) | 2015-07-15 |
| JP5555891B2 (ja) | 2014-07-23 |
| WO2011033358A3 (en) | 2011-07-14 |
| EP2504023A2 (en) | 2012-10-03 |
| JP2013504318A (ja) | 2013-02-07 |
| CN102573884A (zh) | 2012-07-11 |
| AU2010296994A1 (en) | 2012-04-19 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FB | Suspension of granting procedure |