AU2010286168B2 - Tricyclic heterocyclic compounds as phosphoinositide 3-kinase inhibitors - Google Patents
Tricyclic heterocyclic compounds as phosphoinositide 3-kinase inhibitors Download PDFInfo
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- AU2010286168B2 AU2010286168B2 AU2010286168A AU2010286168A AU2010286168B2 AU 2010286168 B2 AU2010286168 B2 AU 2010286168B2 AU 2010286168 A AU2010286168 A AU 2010286168A AU 2010286168 A AU2010286168 A AU 2010286168A AU 2010286168 B2 AU2010286168 B2 AU 2010286168B2
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- C07D495/12—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains three hetero rings
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- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
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Landscapes
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- Nitrogen Condensed Heterocyclic Rings (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
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| EP3053925A1 (en) * | 2010-12-16 | 2016-08-10 | F. Hoffmann-La Roche AG | Tricyclic pi3k inhibitor compounds and methods of use |
| AU2015268776B2 (en) * | 2010-12-16 | 2017-04-13 | Genentech, Inc. | Tricyclic PI3k inhibitor compounds and methods of use |
| CA2857302C (en) | 2011-12-15 | 2020-08-25 | Novartis Ag | Use of inhibitors of the activity or function of pi3k |
| GB201204125D0 (en) | 2012-03-08 | 2012-04-25 | Karus Therapeutics Ltd | Compounds |
| EP2897959B1 (en) * | 2012-09-20 | 2017-12-20 | UDC Ireland Limited | Azadibenzofurans for electronic applications |
| MX364295B (es) | 2012-11-07 | 2019-04-22 | Karus Therapeutics Ltd | Inhibidores de histona desacetilasa novedosos y su uso en terapia. |
| CN104870017B (zh) | 2012-11-08 | 2020-08-14 | 理森制药股份公司 | 含有PDE4抑制剂和PI3δ或双重PI3δ-γ激酶抑制剂的药物组合物 |
| AR095443A1 (es) * | 2013-03-15 | 2015-10-14 | Fundación Centro Nac De Investig Oncológicas Carlos Iii | Heterociclos condensados con acción sobre atr |
| SMT201800501T1 (it) | 2013-05-10 | 2018-11-09 | Karus Therapeutics Ltd | Nuovi inibitori di istone deacetilasi |
| US9814037B2 (en) * | 2013-06-28 | 2017-11-07 | Intel Corporation | Method for efficient channel estimation and beamforming in FDD system by exploiting uplink-downlink correspondence |
| CN104557955B (zh) * | 2013-10-23 | 2017-05-03 | 上海汇伦生命科技有限公司 | 作为PI3K/mTOR抑制剂的三环类化合物，其制备方法和用途 |
| GB201402431D0 (en) | 2014-02-12 | 2014-03-26 | Karus Therapeutics Ltd | Compounds |
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| US10906918B2 (en) * | 2015-12-16 | 2021-02-02 | Genentech, Inc. | Process for the preparation of tricyclic PI3K inhibitor compounds and methods for using the same for the treatment of cancer |
| EP3474846B1 (en) | 2016-06-22 | 2022-11-30 | Vanderbilt University | Positive allosteric modulators of the muscarinic acetylcholine receptor m4 |
| TW201815787A (zh) | 2016-09-23 | 2018-05-01 | 美商基利科學股份有限公司 | 磷脂醯肌醇3-激酶抑制劑 |
| TW201825465A (zh) | 2016-09-23 | 2018-07-16 | 美商基利科學股份有限公司 | 磷脂醯肌醇3-激酶抑制劑 |
| TW201813963A (zh) | 2016-09-23 | 2018-04-16 | 美商基利科學股份有限公司 | 磷脂醯肌醇3-激酶抑制劑 |
| MA46899A (fr) | 2016-11-07 | 2021-04-14 | Univ Vanderbilt | Modulateurs allostériques positifs du récepteur muscarinique de l'acétylcholine m4 |
| EP3534901B1 (en) | 2016-11-07 | 2022-06-22 | Vanderbilt University | Positive allosteric modulators of the muscarinic acetylcholine receptor m4 |
| JP7099725B2 (ja) | 2016-11-07 | 2022-07-12 | ヴァンダービルト ユニヴァーシティ | ムスカリン性アセチルコリンレセプターｍ４のポジティブアロステリック調節因子 |
| GB201702938D0 (en) | 2017-02-23 | 2017-04-12 | Univ Southampton | Methods of generating and screening compartmentalised peptides libraries |
| TW201930311A (zh) | 2017-12-05 | 2019-08-01 | 泛德比爾特大學 | 蕈毒鹼型乙醯膽鹼受體m4之正向別構調節劑 |
| US11376254B2 (en) | 2017-12-05 | 2022-07-05 | Vanderbilt University | Positive allosteric modulators of the muscarinic acetylcholine receptor M4 |
| AU2019207616A1 (en) | 2018-01-10 | 2020-07-09 | Recurium Ip Holdings, Llc | Benzamide compounds |
| WO2022169882A1 (en) | 2021-02-03 | 2022-08-11 | Verge Analytics, Inc. | Methods and treatment of viral infection caused by sars-cov-2 |
| CN117751127A (zh) * | 2021-08-20 | 2024-03-22 | 南京大美生物制药有限公司 | 一种五元含氮杂环并杂芳基类衍生物及其用途 |
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| GB201204125D0 (en) | 2012-03-08 | 2012-04-25 | Karus Therapeutics Ltd | Compounds |
| CN104955824B (zh) | 2012-11-20 | 2017-09-22 | 豪夫迈·罗氏有限公司 | 作为含t790m的egfr突变体的抑制剂的氨基嘧啶化合物 |
| SMT201800501T1 (it) | 2013-05-10 | 2018-11-09 | Karus Therapeutics Ltd | Nuovi inibitori di istone deacetilasi |
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2012
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- 2012-02-07 ZA ZA2012/00910A patent/ZA201200910B/en unknown
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2015
- 2015-10-22 US US14/920,410 patent/US9580442B2/en active Active
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2017
- 2017-01-19 US US15/410,114 patent/US9938290B2/en active Active
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2018
- 2018-03-01 US US15/909,011 patent/US10501478B2/en active Active
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20020151544A1 (en) * | 2000-04-27 | 2002-10-17 | Masahiko Hayakawa | Fused heteroaryl derivatives |
Also Published As
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| CN102498115B (zh) | 2016-12-07 |
| AU2010286168A1 (en) | 2012-03-08 |
| US10501478B2 (en) | 2019-12-10 |
| NZ597983A (en) | 2014-05-30 |
| IL217903A (en) | 2017-08-31 |
| IL217903A0 (en) | 2012-03-29 |
| BR112012003955A2 (pt) | 2017-09-26 |
| MX2012002059A (es) | 2012-04-19 |
| US20190040079A1 (en) | 2019-02-07 |
| EP2467387B1 (en) | 2015-01-07 |
| CA2771594C (en) | 2018-05-01 |
| JP2013502404A (ja) | 2013-01-24 |
| US9938290B2 (en) | 2018-04-10 |
| ZA201200910B (en) | 2013-05-29 |
| IN2012DN01325A (enExample) | 2015-06-05 |
| CA2771594A1 (en) | 2011-02-24 |
| ES2534326T3 (es) | 2015-04-21 |
| JP5746172B2 (ja) | 2015-07-08 |
| WO2011021038A1 (en) | 2011-02-24 |
| US9200007B2 (en) | 2015-12-01 |
| CN102498115A (zh) | 2012-06-13 |
| PL2467387T3 (pl) | 2015-08-31 |
| US20160108057A1 (en) | 2016-04-21 |
| US20120178737A1 (en) | 2012-07-12 |
| US20180009826A1 (en) | 2018-01-11 |
| EP2467387A1 (en) | 2012-06-27 |
| US9580442B2 (en) | 2017-02-28 |
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