AU2010236168B2 - Methods for assessing responsiveness of B-cell lymphoma to treatment with anti-CD40 antibodies - Google Patents

Methods for assessing responsiveness of B-cell lymphoma to treatment with anti-CD40 antibodies Download PDF

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Publication number
AU2010236168B2
AU2010236168B2 AU2010236168A AU2010236168A AU2010236168B2 AU 2010236168 B2 AU2010236168 B2 AU 2010236168B2 AU 2010236168 A AU2010236168 A AU 2010236168A AU 2010236168 A AU2010236168 A AU 2010236168A AU 2010236168 B2 AU2010236168 B2 AU 2010236168B2
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seq
nos
antibody
sample
subject
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AU2010236168A
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AU2010236168A1 (en
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Bart Burington
David Dornan
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Genentech Inc
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Genentech Inc
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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/02Antineoplastic agents specific for leukemia
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6854Immunoglobulins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/505Medicinal preparations containing antigens or antibodies comprising antibodies
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/106Pharmacogenomics, i.e. genetic variability in individual responses to drugs and drug metabolism
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/158Expression markers
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00Detection or diagnosis of diseases
    • G01N2800/52Predicting or monitoring the response to treatment, e.g. for selection of therapy based on assay results in personalised medicine; Prognosis

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Pathology (AREA)
  • Analytical Chemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Oncology (AREA)
  • Biophysics (AREA)
  • General Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Hospice & Palliative Care (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Physics & Mathematics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Cell Biology (AREA)
  • Food Science & Technology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
AU2010236168A 2009-04-18 2010-04-17 Methods for assessing responsiveness of B-cell lymphoma to treatment with anti-CD40 antibodies Ceased AU2010236168B2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2013202908A AU2013202908A1 (en) 2009-04-18 2013-04-08 Methods for assessing responsiveness of B-cell lymphoma to treatment with anti-CD40 antibodies

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US17061509P 2009-04-18 2009-04-18
US61/170,615 2009-04-18
PCT/US2010/031528 WO2010121231A1 (en) 2009-04-18 2010-04-17 Methods for assessing responsiveness of b-cell lymphoma to treatment with anti-cd40 antibodies

Related Child Applications (1)

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AU2013202908A Division AU2013202908A1 (en) 2009-04-18 2013-04-08 Methods for assessing responsiveness of B-cell lymphoma to treatment with anti-CD40 antibodies

Publications (2)

Publication Number Publication Date
AU2010236168A1 AU2010236168A1 (en) 2011-11-10
AU2010236168B2 true AU2010236168B2 (en) 2015-08-13

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AU2010236168A Ceased AU2010236168B2 (en) 2009-04-18 2010-04-17 Methods for assessing responsiveness of B-cell lymphoma to treatment with anti-CD40 antibodies

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US (1) US9617600B2 (enExample)
EP (1) EP2419531B1 (enExample)
JP (1) JP5836929B2 (enExample)
KR (1) KR101787768B1 (enExample)
CN (1) CN102459639A (enExample)
AU (1) AU2010236168B2 (enExample)
BR (1) BRPI1011394A8 (enExample)
CA (1) CA2758523C (enExample)
ES (1) ES2605228T3 (enExample)
IL (1) IL215707A (enExample)
MX (1) MX2011010938A (enExample)
WO (1) WO2010121231A1 (enExample)

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BRPI0820707A2 (pt) 2007-11-07 2015-06-16 Genentech Inc Métodos e composição para avaliar a responsividade do linfoma de células b para o tratamento com anticorpos anti-cd40
CN103635488B (zh) 2011-04-29 2016-12-14 埃派斯进有限公司 抗-cd40抗体及其使用方法
ES2634254T3 (es) 2011-09-12 2017-09-27 Atrys Health, SA Métodos para el pronóstico del linfoma difuso de linfocitos B grandes
HUE049569T2 (hu) 2012-08-09 2020-09-28 Celgene Corp Immunrendszerrel kapcsolatos és gyulladásos megbetegedések kezelése
US20150038511A1 (en) 2012-08-09 2015-02-05 Celgene Corporation Treatment of immune-related and inflammatory diseases
EP2914627B1 (en) 2012-10-30 2021-04-07 Apexigen, Inc. Anti-cd40 antibodies and methods of use
TWI794885B (zh) 2014-05-19 2023-03-01 美商西建公司 全身紅斑性狼瘡之治療
JP2018529344A (ja) * 2015-09-25 2018-10-11 セルジーン コーポレイション びまん性大細胞型b細胞リンパ腫の治療方法及び薬物に対する応答性の予測因子としてのバイオマーカー利用
BR112018076260A2 (pt) 2016-06-20 2019-03-26 Kymab Limited anticorpo ou fragmento do mesmo que se liga especificamente a hpd-l1, anticorpo biespecífico ou proteína de fusão, uso de um anticorpo ou fragmento, método, composição farmacêutica, método de modulação, método de inibição, método de tratamento, ácido nucleico, vetor, hospedeiro e imunocitocina
WO2022120038A1 (en) * 2020-12-02 2022-06-09 Albert Einstein College Of Medicine Method for predicting patient response to cd40-targeted therapies

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Also Published As

Publication number Publication date
CA2758523C (en) 2019-03-12
MX2011010938A (es) 2012-01-12
JP5836929B2 (ja) 2015-12-24
US9617600B2 (en) 2017-04-11
WO2010121231A1 (en) 2010-10-21
AU2010236168A1 (en) 2011-11-10
BRPI1011394A2 (pt) 2016-03-15
IL215707A0 (en) 2012-01-31
IL215707A (en) 2016-08-31
US20120123695A1 (en) 2012-05-17
ES2605228T3 (es) 2017-03-13
CN102459639A (zh) 2012-05-16
EP2419531A1 (en) 2012-02-22
CA2758523A1 (en) 2010-10-21
KR20120013992A (ko) 2012-02-15
JP2012523838A (ja) 2012-10-11
BRPI1011394A8 (pt) 2018-06-26
EP2419531B1 (en) 2016-09-07
KR101787768B1 (ko) 2017-10-18

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