AU2009332951B2 - System and method for ocular iontophoresis with buffering - Google Patents
System and method for ocular iontophoresis with buffering Download PDFInfo
- Publication number
- AU2009332951B2 AU2009332951B2 AU2009332951A AU2009332951A AU2009332951B2 AU 2009332951 B2 AU2009332951 B2 AU 2009332951B2 AU 2009332951 A AU2009332951 A AU 2009332951A AU 2009332951 A AU2009332951 A AU 2009332951A AU 2009332951 B2 AU2009332951 B2 AU 2009332951B2
- Authority
- AU
- Australia
- Prior art keywords
- layer
- delivery device
- buffer
- membrane
- therapeutic substance
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Ceased
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F9/00—Methods or devices for treatment of the eyes; Devices for putting in contact-lenses; Devices to correct squinting; Apparatus to guide the blind; Protective devices for the eyes, carried on the body or in the hand
- A61F9/0008—Introducing ophthalmic products into the ocular cavity or retaining products therein
- A61F9/0026—Ophthalmic product dispenser attachments to facilitate positioning near the eye
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/02—Details
- A61N1/04—Electrodes
- A61N1/0404—Electrodes for external use
- A61N1/0408—Use-related aspects
- A61N1/0428—Specially adapted for iontophoresis, e.g. AC, DC or including drug reservoirs
- A61N1/0444—Membrane
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/18—Applying electric currents by contact electrodes
- A61N1/20—Applying electric currents by contact electrodes continuous direct currents
- A61N1/30—Apparatus for iontophoresis, i.e. transfer of media in ionic state by an electromotoric force into the body, or cataphoresis
- A61N1/303—Constructional details
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/18—Applying electric currents by contact electrodes
- A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
- A61N1/325—Applying electric currents by contact electrodes alternating or intermittent currents for iontophoresis, i.e. transfer of media in ionic state by an electromotoric force into the body
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/02—Details
- A61N1/04—Electrodes
- A61N1/0404—Electrodes for external use
- A61N1/0408—Use-related aspects
- A61N1/0428—Specially adapted for iontophoresis, e.g. AC, DC or including drug reservoirs
- A61N1/0448—Drug reservoir
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Biomedical Technology (AREA)
- Public Health (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Radiology & Medical Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Ophthalmology & Optometry (AREA)
- Heart & Thoracic Surgery (AREA)
- Vascular Medicine (AREA)
- Electrotherapy Devices (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US14199408P | 2008-12-31 | 2008-12-31 | |
| US61/141,994 | 2008-12-31 | ||
| US18060209P | 2009-05-22 | 2009-05-22 | |
| US61/180,602 | 2009-05-22 | ||
| PCT/US2009/069580 WO2010078246A1 (en) | 2008-12-31 | 2009-12-28 | System and method for ocular iontophoresis with buffering |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| AU2009332951A1 AU2009332951A1 (en) | 2011-07-14 |
| AU2009332951B2 true AU2009332951B2 (en) | 2015-06-11 |
Family
ID=42310178
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU2009332951A Ceased AU2009332951B2 (en) | 2008-12-31 | 2009-12-28 | System and method for ocular iontophoresis with buffering |
Country Status (10)
| Country | Link |
|---|---|
| US (2) | US9180292B2 (https=) |
| EP (1) | EP2370155B1 (https=) |
| JP (1) | JP5723293B2 (https=) |
| CN (1) | CN102341146B (https=) |
| AU (1) | AU2009332951B2 (https=) |
| CA (1) | CA2750149C (https=) |
| ES (1) | ES2679673T3 (https=) |
| IL (1) | IL213796A0 (https=) |
| MX (1) | MX2011006925A (https=) |
| WO (1) | WO2010078246A1 (https=) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2679673T3 (es) * | 2008-12-31 | 2018-08-30 | Eyegate Pharmaceuticals, Inc. | Sistema para iontoforesis ocular con amortiguación |
| ES2590127T3 (es) * | 2011-01-12 | 2016-11-18 | Sooft Italia S.P.A. | Administración corneal de agentes de entrecruzamiento por iontoforesis para el tratamiento de queratocono y composiciones oftálmicas relacionadas |
| AU2012307090B2 (en) * | 2011-09-09 | 2016-06-16 | International Scientific Pty Ltd | Method and device for transdermal delivery of substances |
| ITVE20130043A1 (it) * | 2013-07-31 | 2015-02-01 | I A C E R S R L | Dispositivo perfezionato oftalmologico per il trattamento di malattie corneali quali il cheratocono. |
| ES2672327T3 (es) * | 2014-01-27 | 2018-06-13 | Opia Technologies | Dispositivo de iontoforesis ocular |
| MX2017009193A (es) | 2015-01-22 | 2017-12-12 | Eyegate Pharmaceuticals Inc | Lente de contacto iontoforetica. |
| US11787783B2 (en) | 2016-12-13 | 2023-10-17 | Beta Therapeutics Pty Ltd | Heparanase inhibitors and use thereof |
| WO2018107200A1 (en) | 2016-12-13 | 2018-06-21 | Beta Therapeutics Pty Ltd | Heparanase inhibitors and use thereof |
| US12239527B2 (en) * | 2019-03-04 | 2025-03-04 | Tohoku University | Method of absorbing or discharging water of ophthalmic medical device and ophthalmic medical device |
| IT201900010341A1 (it) | 2019-06-27 | 2020-12-27 | Vision Eng Italy Srl | Dispositivo, sistema e metodo di trattamento di un tessuto corneale |
| JP7392142B2 (ja) * | 2019-11-14 | 2023-12-05 | シーメンス ガメサ リニューアブル エナジー エー/エス | 風力タービン用のダンパ |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5980497A (en) * | 1996-03-15 | 1999-11-09 | Yavitz; Edward Q. | Membrane shield for eyes |
| US20050197618A1 (en) * | 2004-03-03 | 2005-09-08 | Iomed, Inc. | Improved buffer gel for iontophoresis electrodes |
| US20070123814A1 (en) * | 2005-11-29 | 2007-05-31 | Eyegate Pharmasa | Ocular iontophoresis device |
Family Cites Families (33)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US551880A (en) | 1895-12-24 | Theodore b | ||
| SU654254A2 (ru) | 1977-02-07 | 1979-03-30 | В. Н. Серов | Устройство дл лечени глаз |
| SU995783A1 (ru) | 1980-07-21 | 1983-02-15 | Омский Государственный Ордена Трудового Красного Знамени Медицинский Институт Им.М.И.Калинина | Устройство дл электрофореза лекарственных веществ в ткани глаза |
| US4678466A (en) | 1981-06-25 | 1987-07-07 | Rosenwald Peter L | Internal medication delivery method and vehicle |
| SU1342500A1 (ru) | 1982-03-09 | 1987-10-07 | Омский государственный медицинский институт им.М.И.Калинина | Способ лечени глаукомы |
| US5053000A (en) | 1985-11-13 | 1991-10-01 | Imperial Chemical Industries Plc | Ocular treatment |
| US4752285B1 (en) | 1986-03-19 | 1995-08-22 | Univ Utah Res Found | Methods and apparatus for iontophoresis application of medicaments |
| IL86076A (en) | 1988-04-14 | 1992-12-01 | Inventor S Funding Corp Ltd | Transdermal drug delivery device |
| US4955378A (en) | 1988-05-02 | 1990-09-11 | University Of South Florida | Apparatus and methods for performing electrofusion at specific anatomical sites |
| JPH04507202A (ja) | 1989-03-17 | 1992-12-17 | カンデラ・レーザー・コーポレーシヨン | 非攻撃的強膜切開レーザー装置および方法 |
| US5174304A (en) | 1990-02-16 | 1992-12-29 | Latina Mark A | Electrocycloablation apparatus and method |
| JPH07501238A (ja) | 1991-08-26 | 1995-02-09 | ラットガーズ,ザ・ステート・ユニバーシティ・オブ・ニュージャージー | 電離療法装置及び方法 |
| US5533971A (en) | 1993-09-03 | 1996-07-09 | Alza Corporation | Reduction of skin irritation during electrotransport |
| US5420109A (en) | 1993-11-12 | 1995-05-30 | Houghten Pharmaceuticals, Inc. | Cytokine restraining agents |
| US5472436A (en) | 1994-07-26 | 1995-12-05 | Fremstad; Daria A. | Ocular appliance for delivering medication |
| AUPM982694A0 (en) | 1994-12-02 | 1995-01-05 | University Of Queensland, The | Iontophoresis method and apparatus |
| JP3459724B2 (ja) * | 1996-03-17 | 2003-10-27 | 久光製薬株式会社 | イオントフォレーシス用電極デバイス |
| US5676648A (en) | 1996-05-08 | 1997-10-14 | The Aps Organization, Llp | Iontophoretic drug delivery apparatus and method for use |
| JPH1072374A (ja) * | 1996-06-20 | 1998-03-17 | Hisamitsu Pharmaceut Co Inc | イオントフォレーシス用薬物投与組成物 |
| DE69804921T2 (de) | 1997-10-28 | 2002-11-07 | Mecanismos Auxiliares Industriales, S.A. M.A.I.S.A. | Anschlusselement für eine Leiterplatte |
| FR2773320B1 (fr) * | 1998-01-05 | 2000-03-03 | Optisinvest | Dispositif pour le transfert intraoculaire de produits actifs par iontophorese |
| EP1150741A1 (en) | 1999-02-10 | 2001-11-07 | GMP Drug Delivery, Inc. | Iontophoresis, electroporation and combination patches for local drug delivery |
| TW539564B (en) | 1999-05-25 | 2003-07-01 | Iomed Inc | Methods and apparatus for ocular iontophoresis |
| US20030023228A1 (en) * | 2001-07-20 | 2003-01-30 | Parkinson Thomas M. | Ocular iontophoretic device and method for using the same |
| FR2830766B1 (fr) | 2001-10-12 | 2004-03-12 | Optis France Sa | Dispositif de delivrance de medicaments par iontophorese transpalpebrale |
| WO2004066980A2 (en) | 2003-01-24 | 2004-08-12 | Control Delivery Systems, Inc. | Sustained release device and method for ocular delivery of carbonic anhydrase inhibitors |
| FR2869531B1 (fr) | 2004-04-30 | 2006-07-14 | Optis France Sa Sa | Dispositif de iontophorese oculaire diminuant les irritations |
| AU2005247122C1 (en) | 2004-04-30 | 2012-02-02 | Eyegate Pharma S.A. | Irritation-reducing ocular iontophoretic device |
| KR20080066712A (ko) | 2005-09-30 | 2008-07-16 | 티티아이 엘뷰 가부시키가이샤 | 관능화된 미세바늘 경피 약물 전달 시스템, 장치 및 방법 |
| US8321008B2 (en) * | 2005-11-30 | 2012-11-27 | Nitric Biotherapeutics, Inc. | Combination cartridge and device for electrokinetic delivery of medicament to a treatment site |
| US8062783B2 (en) | 2006-12-01 | 2011-11-22 | Tti Ellebeau, Inc. | Systems, devices, and methods for powering and/or controlling devices, for instance transdermal delivery devices |
| EP2249921B1 (en) * | 2008-02-25 | 2020-06-17 | Eyegate Pharmaceuticals, Inc. | Enhanced delivery of dexamethasone phosphate to ocular tissues through iontophoresis |
| ES2679673T3 (es) * | 2008-12-31 | 2018-08-30 | Eyegate Pharmaceuticals, Inc. | Sistema para iontoforesis ocular con amortiguación |
-
2009
- 2009-12-28 ES ES09837075.2T patent/ES2679673T3/es active Active
- 2009-12-28 JP JP2011544556A patent/JP5723293B2/ja active Active
- 2009-12-28 EP EP09837075.2A patent/EP2370155B1/en not_active Not-in-force
- 2009-12-28 US US13/141,810 patent/US9180292B2/en not_active Expired - Fee Related
- 2009-12-28 CA CA2750149A patent/CA2750149C/en not_active Expired - Fee Related
- 2009-12-28 WO PCT/US2009/069580 patent/WO2010078246A1/en not_active Ceased
- 2009-12-28 AU AU2009332951A patent/AU2009332951B2/en not_active Ceased
- 2009-12-28 MX MX2011006925A patent/MX2011006925A/es active IP Right Grant
- 2009-12-28 CN CN200980157719.3A patent/CN102341146B/zh not_active Expired - Fee Related
-
2011
- 2011-06-28 IL IL213796A patent/IL213796A0/en unknown
-
2015
- 2015-11-02 US US14/930,193 patent/US9539141B2/en not_active Expired - Fee Related
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5980497A (en) * | 1996-03-15 | 1999-11-09 | Yavitz; Edward Q. | Membrane shield for eyes |
| US20050197618A1 (en) * | 2004-03-03 | 2005-09-08 | Iomed, Inc. | Improved buffer gel for iontophoresis electrodes |
| US20070123814A1 (en) * | 2005-11-29 | 2007-05-31 | Eyegate Pharmasa | Ocular iontophoresis device |
Also Published As
| Publication number | Publication date |
|---|---|
| EP2370155A1 (en) | 2011-10-05 |
| US9539141B2 (en) | 2017-01-10 |
| CA2750149C (en) | 2018-02-27 |
| ES2679673T3 (es) | 2018-08-30 |
| EP2370155A4 (en) | 2012-12-26 |
| CN102341146A (zh) | 2012-02-01 |
| EP2370155B1 (en) | 2018-07-04 |
| IL213796A0 (en) | 2011-07-31 |
| US20160120696A1 (en) | 2016-05-05 |
| US9180292B2 (en) | 2015-11-10 |
| CN102341146B (zh) | 2015-09-23 |
| MX2011006925A (es) | 2011-07-28 |
| AU2009332951A1 (en) | 2011-07-14 |
| US20110301526A1 (en) | 2011-12-08 |
| WO2010078246A1 (en) | 2010-07-08 |
| CA2750149A1 (en) | 2010-07-08 |
| JP5723293B2 (ja) | 2015-05-27 |
| JP2012513875A (ja) | 2012-06-21 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FGA | Letters patent sealed or granted (standard patent) | ||
| MK14 | Patent ceased section 143(a) (annual fees not paid) or expired |