AU2009296653A1 - Therapeutic regimen comprising peg- interferon, ribavirin and VX-950 for the treatment of Hepatitis " - Google Patents

Therapeutic regimen comprising peg- interferon, ribavirin and VX-950 for the treatment of Hepatitis " Download PDF

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Publication number
AU2009296653A1
AU2009296653A1 AU2009296653A AU2009296653A AU2009296653A1 AU 2009296653 A1 AU2009296653 A1 AU 2009296653A1 AU 2009296653 A AU2009296653 A AU 2009296653A AU 2009296653 A AU2009296653 A AU 2009296653A AU 2009296653 A1 AU2009296653 A1 AU 2009296653A1
Authority
AU
Australia
Prior art keywords
weeks
peginterferon
administered
ribavirin
week
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2009296653A
Other languages
English (en)
Inventor
Maria Gloria Beumont
Robert S. Kauffman
Gaston Rafael Picchio
Ramon Polo
Cyril Jean Camille Titeux
Rudolf Peter Gerhard Van Heeswijk
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Janssen Pharmaceutica NV
Vertex Pharmaceuticals Inc
Original Assignee
Janssen Pharmaceutica NV
Vertex Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Janssen Pharmaceutica NV, Vertex Pharmaceuticals Inc filed Critical Janssen Pharmaceutica NV
Publication of AU2009296653A1 publication Critical patent/AU2009296653A1/en
Assigned to VERTEX PHARMACEUTICALS INCORPORATED, JASSEN PHARMACEUTICA NV reassignment VERTEX PHARMACEUTICALS INCORPORATED Amend patent request/document other than specification (104) Assignors: VERTEX PHARMACEUTICALS INCORPORATED
Abandoned legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19Cytokines; Lymphokines; Interferons
    • A61K38/21Interferons [IFN]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19Cytokines; Lymphokines; Interferons
    • A61K38/21Interferons [IFN]
    • A61K38/212IFN-alpha
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7052Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
    • A61K31/7056Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing five-membered rings with nitrogen as a ring hetero atom
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/04Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/07Tetrapeptides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/18Drugs for disorders of the alimentary tract or the digestive system for pancreatic disorders, e.g. pancreatic enzymes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/20Antivirals for DNA viruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Virology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Biotechnology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
AU2009296653A 2008-09-24 2009-09-24 Therapeutic regimen comprising peg- interferon, ribavirin and VX-950 for the treatment of Hepatitis " Abandoned AU2009296653A1 (en)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US9984908P 2008-09-24 2008-09-24
US61/099,849 2008-09-24
US10965508P 2008-10-30 2008-10-30
US61/109,655 2008-10-30
US24304109P 2009-09-16 2009-09-16
US61/243,041 2009-09-16
PCT/US2009/058218 WO2010036799A1 (en) 2008-09-24 2009-09-24 Therapeutic regimen comprising peg- interferon, ribavirin and vx-950 for the treatment of hepatitis "

Publications (1)

Publication Number Publication Date
AU2009296653A1 true AU2009296653A1 (en) 2010-04-01

Family

ID=41396114

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2009296653A Abandoned AU2009296653A1 (en) 2008-09-24 2009-09-24 Therapeutic regimen comprising peg- interferon, ribavirin and VX-950 for the treatment of Hepatitis "

Country Status (11)

Country Link
US (2) US20110236351A1 (enExample)
EP (1) EP2328656A1 (enExample)
JP (1) JP2012503669A (enExample)
KR (1) KR20110074870A (enExample)
CN (1) CN102316935A (enExample)
AU (1) AU2009296653A1 (enExample)
CA (1) CA2738477A1 (enExample)
EA (1) EA201170484A1 (enExample)
IL (1) IL211810A0 (enExample)
MX (1) MX2011003121A (enExample)
WO (1) WO2010036799A1 (enExample)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8399615B2 (en) 2005-08-19 2013-03-19 Vertex Pharmaceuticals Incorporated Processes and intermediates
EP2358736A1 (en) * 2008-10-15 2011-08-24 Intermune, Inc. Therapeutic antiviral peptides
JP2012517478A (ja) * 2009-02-12 2012-08-02 バーテックス ファーマシューティカルズ インコーポレイテッド ペグ化インターフェロン、リバビリンおよびテラプレビルを含む、hcv組合せ治療剤
TW201116540A (en) * 2009-10-01 2011-05-16 Intermune Inc Therapeutic antiviral peptides
US8492386B2 (en) 2011-10-21 2013-07-23 Abbvie Inc. Methods for treating HCV
CH707030B1 (de) 2011-10-21 2015-03-13 Abbvie Inc Kombinationsbehandlung von DAAs zur Verwendung in der Behandlung von HCV
US8466159B2 (en) 2011-10-21 2013-06-18 Abbvie Inc. Methods for treating HCV
ES2529143B1 (es) 2011-10-21 2015-10-26 Abbvie Inc. Combinación de al menos dos agentes antivirales de acción directa, ribavirina pero no interferón para uso de tratamiento del vhc
EP3448392A4 (en) 2016-04-28 2020-01-15 Emory University ALKYNOUS THERAPEUTIC NUCLEOTIDE AND NUCLEOSIDE COMPOSITIONS AND RELATED APPLICATIONS

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AR049297A1 (es) * 2004-06-08 2006-07-12 Vertex Pharma Una composicion farmaceutica y dispersiones solidas de vx-950 (inhibidor de la proteasa de hcv ns3/4a) y proceso de obtencion
TWI437990B (zh) * 2004-10-29 2014-05-21 Vertex Pharma Vx-950之醫藥用途
RU2008146518A (ru) * 2006-04-26 2010-06-10 Вертекс Фармасьютикалз Инкорпорейтед (Us) Биомаркеры инфекции, вызываемой вирусом гепатита с
CN101854936A (zh) * 2007-05-21 2010-10-06 弗特克斯药品有限公司 包含vx-950的剂型及其给药方案

Also Published As

Publication number Publication date
US20130101554A1 (en) 2013-04-25
KR20110074870A (ko) 2011-07-04
IL211810A0 (en) 2011-06-30
WO2010036799A1 (en) 2010-04-01
EA201170484A1 (ru) 2012-03-30
MX2011003121A (es) 2011-04-21
CA2738477A1 (en) 2010-04-01
JP2012503669A (ja) 2012-02-09
US8871812B2 (en) 2014-10-28
CN102316935A (zh) 2012-01-11
US20110236351A1 (en) 2011-09-29
EP2328656A1 (en) 2011-06-08

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Legal Events

Date Code Title Description
TH Corrigenda

Free format text: IN VOL 25, NO 20, PAGE(S) 2481 UNDER THE HEADING CHANGE OF NAMES(S) OF APPLICANT(S), SECTION 104 - 2009 UNDER THE NAME JASSEN PHARMACEUTICA NV, APPLICATION NO. 2009296653, UNDER INID (71) CORRECT THE APPLICANT NAME TO JANSSEN PHARMACEUTICA NV

MK4 Application lapsed section 142(2)(d) - no continuation fee paid for the application