AU2009248735B2 - Expression vector encoding alphavirus replicase and the use thereof as immunological adjuvant - Google Patents
Expression vector encoding alphavirus replicase and the use thereof as immunological adjuvant Download PDFInfo
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- AU2009248735B2 AU2009248735B2 AU2009248735A AU2009248735A AU2009248735B2 AU 2009248735 B2 AU2009248735 B2 AU 2009248735B2 AU 2009248735 A AU2009248735 A AU 2009248735A AU 2009248735 A AU2009248735 A AU 2009248735A AU 2009248735 B2 AU2009248735 B2 AU 2009248735B2
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-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/53—DNA (RNA) vaccination
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55516—Proteins; Peptides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
- C07K2319/09—Fusion polypeptide containing a localisation/targetting motif containing a nuclear localisation signal
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/20011—Papillomaviridae
- C12N2710/20022—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
- C12N2770/00011—Details
- C12N2770/36011—Togaviridae
- C12N2770/36111—Alphavirus, e.g. Sindbis virus, VEE, EEE, WEE, Semliki
- C12N2770/36122—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
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- Health & Medical Sciences (AREA)
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- Chemical Kinetics & Catalysis (AREA)
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- Pharmacology & Pharmacy (AREA)
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- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
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- General Engineering & Computer Science (AREA)
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- Communicable Diseases (AREA)
- Mycology (AREA)
- Epidemiology (AREA)
- Gastroenterology & Hepatology (AREA)
- Biophysics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- AIDS & HIV (AREA)
- Tropical Medicine & Parasitology (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Enzymes And Modification Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
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| US61/071,898 | 2008-05-23 | ||
| PCT/EP2009/056240 WO2009141434A1 (en) | 2008-05-23 | 2009-05-22 | Expression vector encoding alphavirus replicase and the use thereof as immunological adjuvant |
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| AU2009248735A1 AU2009248735A1 (en) | 2009-11-26 |
| AU2009248735B2 true AU2009248735B2 (en) | 2015-08-20 |
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| GB201220119D0 (en) * | 2012-11-08 | 2012-12-26 | Univ Cork | Vector |
| CN111304201B (zh) * | 2020-02-21 | 2022-10-21 | 华南农业大学 | 一种降低乙型脑炎脑病毒感染的siRNA及其应用 |
| AU2021233816A1 (en) | 2020-03-09 | 2022-10-06 | Arcturus Therapeutics, Inc. | Coronavirus vaccine compositions and methods |
| BR112023002642A2 (pt) | 2020-08-14 | 2023-04-04 | Arcturus Therapeutics Inc | Método para liofilizar nanopartículas lipídicas |
| CN113846113B (zh) * | 2021-09-09 | 2022-09-13 | 臻赫医药(杭州)有限公司 | 一种有限自我复制mRNA分子系统、制备方法及应用 |
| WO2023133509A2 (en) * | 2022-01-08 | 2023-07-13 | Carogen Corporation | Multi-antigen therapeutic vaccines to treat or prevent chronic hepatitis b virus infection |
| KR20240049429A (ko) | 2022-10-08 | 2024-04-16 | 최주언 | 황금비율 계량컵 |
Citations (2)
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|---|---|---|---|---|
| WO1995027044A1 (en) * | 1994-03-31 | 1995-10-12 | Bioption Ab | ALPHAVIRUS cDNA VECTORS |
| WO2008119827A1 (en) * | 2007-04-02 | 2008-10-09 | Fit Biotech Oy | Transreplicase constructs |
Family Cites Families (11)
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| US5763584A (en) * | 1992-05-18 | 1998-06-09 | Genentech, Inc. | Receptor activation with hepatocyte growth factor agonists |
| SE9401709D0 (sv) * | 1994-05-18 | 1994-05-18 | Mathilda Sjoeberg | Improved alphavirus vectors for expression of heterologous DNA |
| JP2002521461A (ja) * | 1998-07-29 | 2002-07-16 | インビトロゲン・コーポレーション | Ｒｎａウイルスを用いる組換えタンパク質の調節発現 |
| EP1226238A2 (en) * | 1999-10-27 | 2002-07-31 | Cytos Biotechnology AG | Method for creating divergent populations of nucleic acid molecules and proteins |
| US7592005B2 (en) * | 2000-12-28 | 2009-09-22 | Kirin Beer Kabushiki Kaisha | Monoclonal antibody |
| FI116851B (fi) * | 2001-05-03 | 2006-03-15 | Fit Biotech Oyj Plc | Ilmentämisvektori, sen käyttöjä ja menetelmä sen valmistamiseksi sekä sitä sisältäviä tuotteita |
| AU2003266301A1 (en) * | 2002-08-22 | 2004-03-11 | Cytos Biotechnology Ag | Inducible alphaviral/orip based gene expression system |
| ES2222095B1 (es) * | 2003-07-02 | 2005-11-16 | Instituto Nacional De Investigacion Y Tecnologia Agraria Y Alimentaria Inia | Virus adn recombinantes que comprenden un adn complementario de un replicon de un virus arn y sus aplicaciones. |
| WO2006085983A2 (en) * | 2004-07-09 | 2006-08-17 | University Of North Carolina At Chapel Hill | Viral adjuvants |
| WO2008085557A2 (en) * | 2006-09-12 | 2008-07-17 | Alphavax, Inc. | Alphavirus replicon particles encoding il- 12 as immunological adjuvants |
| HRP20100638T2 (hr) * | 2006-11-28 | 2011-03-31 | Proyecto De Biomedicina Cima | Viralni vektori i njihova uporaba |
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2009
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- 2009-05-22 CN CN200980118773.7A patent/CN102083463B/zh not_active Expired - Fee Related
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2010
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Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1995027044A1 (en) * | 1994-03-31 | 1995-10-12 | Bioption Ab | ALPHAVIRUS cDNA VECTORS |
| WO2008119827A1 (en) * | 2007-04-02 | 2008-10-09 | Fit Biotech Oy | Transreplicase constructs |
Non-Patent Citations (1)
| Title |
|---|
| BREAKWELL L. et al, Journal of Virology, 2007, vol. 81(16), pg. 8677-8684 * |
Also Published As
| Publication number | Publication date |
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| AU2009248735A1 (en) | 2009-11-26 |
| JP2011523642A (ja) | 2011-08-18 |
| CN102083463A (zh) | 2011-06-01 |
| RU2010152562A (ru) | 2012-06-27 |
| IL209077A0 (en) | 2011-01-31 |
| CN102083463B (zh) | 2017-04-05 |
| BRPI0913045A2 (pt) | 2017-05-23 |
| WO2009141434A1 (en) | 2009-11-26 |
| JP5663474B2 (ja) | 2015-02-04 |
| EP2296702A1 (en) | 2011-03-23 |
| MX2010012587A (es) | 2011-05-25 |
| SG191600A1 (en) | 2013-07-31 |
| CA2724570A1 (en) | 2009-11-26 |
| US20110171255A1 (en) | 2011-07-14 |
| WO2009141434A4 (en) | 2010-01-14 |
| NZ589495A (en) | 2012-06-29 |
| ZA201007880B (en) | 2012-02-29 |
| US9474800B2 (en) | 2016-10-25 |
| KR20110044836A (ko) | 2011-05-02 |
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