AU2009217224B2 - Humanized anti-C5aR antibodies - Google Patents

Humanized anti-C5aR antibodies Download PDF

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Publication number
AU2009217224B2
AU2009217224B2 AU2009217224A AU2009217224A AU2009217224B2 AU 2009217224 B2 AU2009217224 B2 AU 2009217224B2 AU 2009217224 A AU2009217224 A AU 2009217224A AU 2009217224 A AU2009217224 A AU 2009217224A AU 2009217224 B2 AU2009217224 B2 AU 2009217224B2
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AU
Australia
Prior art keywords
antibody
seq
amino acid
acid sequence
human
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Ceased
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AU2009217224A
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AU2009217224A1 (en
Inventor
Charles Mackay
Peter Whitfeld
David Zahra
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G2 Inflammation Pty Ltd
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G2 Inflammation Pty Ltd
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Publication of AU2009217224A1 publication Critical patent/AU2009217224A1/en
Application granted granted Critical
Publication of AU2009217224B2 publication Critical patent/AU2009217224B2/en
Ceased legal-status Critical Current
Anticipated expiration legal-status Critical

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/46—Hybrid immunoglobulins
    • C07K16/461—Igs containing Ig-regions, -domains or -residues form different species
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/06—Antipsoriatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2896—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against molecules with a "CD"-designation, not provided for elsewhere
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Pulmonology (AREA)
  • Transplantation (AREA)
  • Dermatology (AREA)
  • Pain & Pain Management (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Oncology (AREA)
  • Cardiology (AREA)
  • Communicable Diseases (AREA)
  • Rheumatology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
AU2009217224A 2008-02-20 2009-02-19 Humanized anti-C5aR antibodies Ceased AU2009217224B2 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US6653908P 2008-02-20 2008-02-20
US61/066,539 2008-02-20
PCT/AU2009/000184 WO2009103113A1 (en) 2008-02-20 2009-02-19 HUMANIZED ANTI-C5aR ANTIBODIES

Publications (2)

Publication Number Publication Date
AU2009217224A1 AU2009217224A1 (en) 2009-08-27
AU2009217224B2 true AU2009217224B2 (en) 2014-09-11

Family

ID=40984994

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2009217224A Ceased AU2009217224B2 (en) 2008-02-20 2009-02-19 Humanized anti-C5aR antibodies

Country Status (14)

Country Link
US (3) US8268972B2 (enExample)
EP (2) EP2254911B1 (enExample)
JP (2) JP2011515073A (enExample)
KR (1) KR20100117120A (enExample)
CN (2) CN104193824A (enExample)
AU (1) AU2009217224B2 (enExample)
BR (1) BRPI0907532A2 (enExample)
CA (1) CA2714296A1 (enExample)
ES (1) ES2562627T3 (enExample)
IL (1) IL207217A (enExample)
MX (1) MX2010009190A (enExample)
RU (1) RU2010138612A (enExample)
WO (1) WO2009103113A1 (enExample)
ZA (1) ZA201005348B (enExample)

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KR20110039218A (ko) 2008-06-30 2011-04-15 노보 노르디스크 에이/에스 항－인간 인터루킨－２０ 항체
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JP6511200B1 (ja) * 2017-12-14 2019-05-15 硬化クローム工業株式会社 冷却ロール、およびそれを用いた熱可塑性樹脂シートの製造方法
JP2021527062A (ja) * 2018-06-07 2021-10-11 ケモセントリックス，インコーポレイティド ＡＮＣＡ関連血管炎に対するｃ５ａアンタゴニストの投薬及び効果
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Also Published As

Publication number Publication date
AU2009217224A1 (en) 2009-08-27
US20130129721A1 (en) 2013-05-23
CN101970494B (zh) 2015-01-21
ZA201005348B (en) 2011-10-26
JP2011515073A (ja) 2011-05-19
EP2826791A2 (en) 2015-01-21
EP2254911B1 (en) 2015-11-25
ES2562627T3 (es) 2016-03-07
US8808701B2 (en) 2014-08-19
RU2010138612A (ru) 2012-03-27
US20120315275A1 (en) 2012-12-13
CN104193824A (zh) 2014-12-10
US8268972B2 (en) 2012-09-18
WO2009103113A1 (en) 2009-08-27
MX2010009190A (es) 2010-09-10
IL207217A0 (en) 2010-12-30
BRPI0907532A2 (pt) 2015-07-28
US8361468B2 (en) 2013-01-29
US20110190477A1 (en) 2011-08-04
KR20100117120A (ko) 2010-11-02
JP6034826B2 (ja) 2016-11-30
EP2826791A3 (en) 2015-07-29
JP2014193164A (ja) 2014-10-09
IL207217A (en) 2015-03-31
CA2714296A1 (en) 2009-08-27
CN101970494A (zh) 2011-02-09
EP2254911A4 (en) 2011-10-19
EP2254911A1 (en) 2010-12-01

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