AU2008317315A1 - Pharmaceutical formulation of clavulanic acid - Google Patents
Pharmaceutical formulation of clavulanic acid Download PDFInfo
- Publication number
- AU2008317315A1 AU2008317315A1 AU2008317315A AU2008317315A AU2008317315A1 AU 2008317315 A1 AU2008317315 A1 AU 2008317315A1 AU 2008317315 A AU2008317315 A AU 2008317315A AU 2008317315 A AU2008317315 A AU 2008317315A AU 2008317315 A1 AU2008317315 A1 AU 2008317315A1
- Authority
- AU
- Australia
- Prior art keywords
- clavulanate
- pharmaceutical composition
- clavulanic acid
- tablet
- mixture
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
- HZZVJAQRINQKSD-PBFISZAISA-N clavulanic acid Chemical compound OC(=O)[C@H]1C(=C/CO)/O[C@@H]2CC(=O)N21 HZZVJAQRINQKSD-PBFISZAISA-N 0.000 title claims description 167
- HZZVJAQRINQKSD-UHFFFAOYSA-N Clavulanic acid Natural products OC(=O)C1C(=CCO)OC2CC(=O)N21 HZZVJAQRINQKSD-UHFFFAOYSA-N 0.000 title claims description 157
- 229960003324 clavulanic acid Drugs 0.000 title claims description 36
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- ABVRVIZBZKUTMK-JSYANWSFSA-M potassium clavulanate Chemical group [K+].[O-]C(=O)[C@H]1C(=C/CO)/O[C@@H]2CC(=O)N21 ABVRVIZBZKUTMK-JSYANWSFSA-M 0.000 claims description 66
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Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/42—Oxazoles
- A61K31/424—Oxazoles condensed with heterocyclic ring systems, e.g. clavulanic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1682—Processes
- A61K9/1694—Processes resulting in granules or microspheres of the matrix type containing more than 5% of excipient
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/2027—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Medicinal Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Molecular Biology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US99607907P | 2007-10-26 | 2007-10-26 | |
| US60/996,079 | 2007-10-26 | ||
| PCT/US2008/012126 WO2009055038A1 (en) | 2007-10-26 | 2008-10-24 | Pharmaceutical formulation of clavulanic acid |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AU2008317315A1 true AU2008317315A1 (en) | 2009-04-30 |
Family
ID=40579869
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU2008317315A Abandoned AU2008317315A1 (en) | 2007-10-26 | 2008-10-24 | Pharmaceutical formulation of clavulanic acid |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US20090270358A1 (enExample) |
| EP (1) | EP2214680A4 (enExample) |
| JP (1) | JP2011500811A (enExample) |
| KR (1) | KR20100101574A (enExample) |
| CN (1) | CN101918004A (enExample) |
| AU (1) | AU2008317315A1 (enExample) |
| BR (1) | BRPI0818702A2 (enExample) |
| CA (1) | CA2703224A1 (enExample) |
| IL (1) | IL205313A0 (enExample) |
| MX (1) | MX2010004556A (enExample) |
| WO (1) | WO2009055038A1 (enExample) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20100255099A1 (en) * | 2007-10-26 | 2010-10-07 | Rexahn Pharmaceuticals, Inc. | Clavulanate formulation for neuroprotection and treatment of neurodegenerative disorders |
| US7635773B2 (en) | 2008-04-28 | 2009-12-22 | Cydex Pharmaceuticals, Inc. | Sulfoalkyl ether cyclodextrin compositions |
| KR101628095B1 (ko) | 2010-10-18 | 2016-06-08 | 현대자동차 주식회사 | 저압 ｅｇｒ시스템 제어장치 및 방법 |
| CN102058584B (zh) * | 2010-12-30 | 2012-01-25 | 石药集团河北中润制药有限公司 | 克拉维酸钾/微晶纤维素组合物的制备方法 |
| US9751957B2 (en) | 2012-02-15 | 2017-09-05 | Cydex Pharmaceuticals, Inc. | Manufacturing process for cyclodextrin derivatives |
| KR102112119B1 (ko) | 2012-10-22 | 2020-05-19 | 사이덱스 파마슈티칼스, 인크. | 알킬화된 시클로덱스트린 조성물 및 이의 제조 및 사용 방법 |
| EP2919903B1 (en) | 2012-11-14 | 2020-07-22 | W.R. Grace & CO. - CONN. | Compositions containing a biologically active material and a non-ordered inorganic oxide |
| WO2015153984A2 (en) | 2014-04-04 | 2015-10-08 | Pharmaquest International Center, LLC | Disintegrating monolithic modified release tablets containing quadri-layer extended release granules |
Family Cites Families (17)
| Publication number | Priority date | Publication date | Assignee | Title |
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| JO984B1 (en) * | 1977-10-11 | 1979-12-01 | بيتشام غروب ليمتد | A dry pharmaceutical compound with a suitable dosage unit for oral administration |
| NZ189022A (en) * | 1977-12-08 | 1981-11-19 | Beecham Group Ltd | Pharmaceutically acceptable particles of clavulanates dispersed in a polymeric binder |
| NZ198241A (en) * | 1980-09-27 | 1983-12-16 | Beecham Group Ltd | Tablet containing amoxycillin and potassium clavulanate |
| GB9109862D0 (en) | 1991-05-08 | 1991-07-03 | Beecham Lab Sa | Pharmaceutical formulations |
| GB9405856D0 (en) * | 1994-03-24 | 1994-05-11 | Smithkline Beecham Plc | Pharmaceutical formulation |
| GB9518917D0 (en) * | 1995-09-15 | 1995-11-15 | Smithkline Beecham Plc | Compounds |
| IE990159A1 (en) * | 1999-02-26 | 2000-09-20 | Fuisz Internat Ltd | Storage Stable Amoxycillin and Clavulanate Suspension Composition. |
| BR0013366A (pt) | 1999-08-16 | 2002-07-23 | Revaax Pharmaceuticals Llc | Métodos para tratar um distúrbio comportamental, um paciente humano, doença de próstata, distúrbios de ansiedade e cognitivos em um paciente humano afligido com uma condição ou disposto ao desenvolvimento de uma condição distinguida pelo menos em parte pela concentração de glutamato extracelular anormal no cérebro ou em outro tecido nervoso, distúrbio comportamental nas espécies humana, canina, felina e equina e um paciente afligido com ou disposto a desenvolver uma doença compreendendo concentrações de glutamato anormalmente elevadas em tecido neuronal ou nìveis de naaladase elevados em tecido prostático e com esclerose múltipla e para realçar a função cognitiva, formulação farmacêutica e usos de um inibidor da atividade de peptidase de uma dipeptidase ácida ligada em alfa n-acetilada e de um composto de beta-lactama |
| US6489319B2 (en) * | 1999-08-16 | 2002-12-03 | Revaax Pharmaceuticals, Llc | Neurotherapeutic use of carboxypeptidase inhibitors |
| US6426342B2 (en) * | 1999-08-16 | 2002-07-30 | Revaax Pharmaceuticals, Llc | Use of β-lactamase inhibitors as neuroprotectants |
| US7166626B2 (en) | 2001-06-18 | 2007-01-23 | Revaax Pharmaceuticals, Llc | Therapeutic treatment for sexual dysfunction |
| IL154370A0 (en) * | 2003-02-10 | 2003-09-17 | Chemagis Ltd | Solid amorphous mixtures, processes for the preparation thereof and pharmaceutical compositions containing the same |
| SI21402A (sl) * | 2003-02-12 | 2004-08-31 | LEK farmacevtska dru�ba d.d. | Obloženi delci in farmacevtske oblike |
| PE20060489A1 (es) * | 2004-08-13 | 2006-06-19 | Schering Plough Ltd | Formulacion farmaceutica que comprende un antibiotico, un triazol y un corticosteroide |
| DE102006007830A1 (de) * | 2006-02-17 | 2007-08-30 | Grünenthal GmbH | Lagerstabile orale Darreichungsform von Amoxicillin und Clavulansäure |
| CA2644911A1 (en) * | 2006-03-24 | 2007-10-04 | Panacea Biotec Ltd. | Antibiotic compositions of modified release and process of production thereof |
| US20100255099A1 (en) * | 2007-10-26 | 2010-10-07 | Rexahn Pharmaceuticals, Inc. | Clavulanate formulation for neuroprotection and treatment of neurodegenerative disorders |
-
2008
- 2008-10-24 MX MX2010004556A patent/MX2010004556A/es not_active Application Discontinuation
- 2008-10-24 CA CA2703224A patent/CA2703224A1/en not_active Abandoned
- 2008-10-24 EP EP20080842941 patent/EP2214680A4/en not_active Withdrawn
- 2008-10-24 KR KR1020107011374A patent/KR20100101574A/ko not_active Withdrawn
- 2008-10-24 AU AU2008317315A patent/AU2008317315A1/en not_active Abandoned
- 2008-10-24 CN CN2008801224638A patent/CN101918004A/zh active Pending
- 2008-10-24 JP JP2010531050A patent/JP2011500811A/ja active Pending
- 2008-10-24 BR BRPI0818702 patent/BRPI0818702A2/pt not_active IP Right Cessation
- 2008-10-24 WO PCT/US2008/012126 patent/WO2009055038A1/en not_active Ceased
- 2008-10-24 US US12/258,062 patent/US20090270358A1/en not_active Abandoned
-
2010
- 2010-04-25 IL IL205313A patent/IL205313A0/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| JP2011500811A (ja) | 2011-01-06 |
| IL205313A0 (en) | 2010-12-30 |
| CN101918004A (zh) | 2010-12-15 |
| EP2214680A1 (en) | 2010-08-11 |
| WO2009055038A1 (en) | 2009-04-30 |
| MX2010004556A (es) | 2010-07-01 |
| EP2214680A4 (en) | 2010-12-29 |
| BRPI0818702A2 (pt) | 2015-04-22 |
| CA2703224A1 (en) | 2009-04-30 |
| KR20100101574A (ko) | 2010-09-17 |
| US20090270358A1 (en) | 2009-10-29 |
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