JP2011500811A - クラブラン酸の医薬品製剤 - Google Patents
クラブラン酸の医薬品製剤 Download PDFInfo
- Publication number
- JP2011500811A JP2011500811A JP2010531050A JP2010531050A JP2011500811A JP 2011500811 A JP2011500811 A JP 2011500811A JP 2010531050 A JP2010531050 A JP 2010531050A JP 2010531050 A JP2010531050 A JP 2010531050A JP 2011500811 A JP2011500811 A JP 2011500811A
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- JP
- Japan
- Prior art keywords
- clavulanate
- pharmaceutical composition
- clavulanic acid
- mixture
- potassium
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Classifications
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/42—Oxazoles
- A61K31/424—Oxazoles condensed with heterocyclic ring systems, e.g. clavulanic acid
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1682—Processes
- A61K9/1694—Processes resulting in granules or microspheres of the matrix type containing more than 5% of excipient
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- A—HUMAN NECESSITIES
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- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
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- A61K9/2004—Excipients; Inactive ingredients
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- A—HUMAN NECESSITIES
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- A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
Landscapes
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- Animal Behavior & Ethology (AREA)
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- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Molecular Biology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (2)
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| US99607907P | 2007-10-26 | 2007-10-26 | |
| PCT/US2008/012126 WO2009055038A1 (en) | 2007-10-26 | 2008-10-24 | Pharmaceutical formulation of clavulanic acid |
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| JP2011500811A true JP2011500811A (ja) | 2011-01-06 |
| JP2011500811A5 JP2011500811A5 (enExample) | 2011-12-08 |
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| US (1) | US20090270358A1 (enExample) |
| EP (1) | EP2214680A4 (enExample) |
| JP (1) | JP2011500811A (enExample) |
| KR (1) | KR20100101574A (enExample) |
| CN (1) | CN101918004A (enExample) |
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| BR (1) | BRPI0818702A2 (enExample) |
| CA (1) | CA2703224A1 (enExample) |
| IL (1) | IL205313A0 (enExample) |
| MX (1) | MX2010004556A (enExample) |
| WO (1) | WO2009055038A1 (enExample) |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| US7635773B2 (en) | 2008-04-28 | 2009-12-22 | Cydex Pharmaceuticals, Inc. | Sulfoalkyl ether cyclodextrin compositions |
| JP2012525427A (ja) * | 2009-04-29 | 2012-10-22 | レクサン ファーマシューティカルズ インコーポレイテッド | 神経保護および神経変性疾患の治療のためのクラブラン酸塩製剤 |
| KR101628095B1 (ko) | 2010-10-18 | 2016-06-08 | 현대자동차 주식회사 | 저압 ｅｇｒ시스템 제어장치 및 방법 |
| CN102058584B (zh) * | 2010-12-30 | 2012-01-25 | 石药集团河北中润制药有限公司 | 克拉维酸钾/微晶纤维素组合物的制备方法 |
| HUE058834T2 (hu) | 2012-02-15 | 2022-09-28 | Cydex Pharmaceuticals Inc | Elõállítási eljárás ciklodextrin-származékokhoz |
| WO2014066274A1 (en) | 2012-10-22 | 2014-05-01 | Cydex Pharmaceuticals, Inc. | Alkylated cyclodextrin compositions and processes for preparing and using the same |
| US10835495B2 (en) | 2012-11-14 | 2020-11-17 | W. R. Grace & Co.-Conn. | Compositions containing a biologically active material and a non-ordered inorganic oxide material and methods of making and using the same |
| US11813361B2 (en) | 2014-04-04 | 2023-11-14 | Pharmaquest International Center, Llp | Disintegrating monolithic modified release tablets containing quadri-layer extended release granules |
Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1997010247A1 (en) * | 1995-09-15 | 1997-03-20 | Smithkline Beecham P.L.C. | Clavulanic acid derivatives for treating atherosclerosis |
| JPH09510470A (ja) * | 1994-03-24 | 1997-10-21 | スミスクライン・ビーチャム・パブリック・リミテッド・カンパニー | ベータ−ラクタム抗生物質およびアルキル硫酸塩の界面活性剤を含有する医薬処方 |
| US6610681B1 (en) * | 1999-08-16 | 2003-08-26 | Revaax Pharmaceuticals, Llc | Neurotherapeutic clavulanate composition and method |
| WO2004071486A1 (en) * | 2003-02-10 | 2004-08-26 | Chemagis Ltd. | Solid amorphous mixtures, processes for the preparation thereof and pharmaceutical compositions containing the same |
| WO2007110875A1 (en) * | 2006-03-24 | 2007-10-04 | Panacea Biotec Ltd. | Antibiotic compositions of modified release and process of production thereof |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JO984B1 (en) * | 1977-10-11 | 1979-12-01 | بيتشام غروب ليمتد | A dry pharmaceutical compound with a suitable dosage unit for oral administration |
| NZ189022A (en) * | 1977-12-08 | 1981-11-19 | Beecham Group Ltd | Pharmaceutically acceptable particles of clavulanates dispersed in a polymeric binder |
| NZ198241A (en) * | 1980-09-27 | 1983-12-16 | Beecham Group Ltd | Tablet containing amoxycillin and potassium clavulanate |
| GB9109862D0 (en) | 1991-05-08 | 1991-07-03 | Beecham Lab Sa | Pharmaceutical formulations |
| IE990159A1 (en) * | 1999-02-26 | 2000-09-20 | Fuisz Internat Ltd | Storage Stable Amoxycillin and Clavulanate Suspension Composition. |
| US6426342B2 (en) * | 1999-08-16 | 2002-07-30 | Revaax Pharmaceuticals, Llc | Use of β-lactamase inhibitors as neuroprotectants |
| US6489319B2 (en) * | 1999-08-16 | 2002-12-03 | Revaax Pharmaceuticals, Llc | Neurotherapeutic use of carboxypeptidase inhibitors |
| WO2002102378A1 (en) | 2001-06-18 | 2002-12-27 | Revaax Pharmaceuticals, Llc | Therapeutic treatment for sexual dysfunction |
| SI21402A (sl) * | 2003-02-12 | 2004-08-31 | LEK farmacevtska dru�ba d.d. | Obloženi delci in farmacevtske oblike |
| CA2576589C (en) * | 2004-08-13 | 2013-11-12 | Schering-Plough Ltd. | Pharmaceutical formulation comprising an antibiotic, a triazole and a corticosteroid |
| DE102006007830A1 (de) * | 2006-02-17 | 2007-08-30 | Grünenthal GmbH | Lagerstabile orale Darreichungsform von Amoxicillin und Clavulansäure |
| JP2012525427A (ja) * | 2009-04-29 | 2012-10-22 | レクサン ファーマシューティカルズ インコーポレイテッド | 神経保護および神経変性疾患の治療のためのクラブラン酸塩製剤 |
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- 2008-10-24 CA CA2703224A patent/CA2703224A1/en not_active Abandoned
- 2008-10-24 EP EP20080842941 patent/EP2214680A4/en not_active Withdrawn
- 2008-10-24 BR BRPI0818702 patent/BRPI0818702A2/pt not_active IP Right Cessation
- 2008-10-24 US US12/258,062 patent/US20090270358A1/en not_active Abandoned
- 2008-10-24 AU AU2008317315A patent/AU2008317315A1/en not_active Abandoned
- 2008-10-24 MX MX2010004556A patent/MX2010004556A/es not_active Application Discontinuation
- 2008-10-24 WO PCT/US2008/012126 patent/WO2009055038A1/en not_active Ceased
- 2008-10-24 CN CN2008801224638A patent/CN101918004A/zh active Pending
- 2008-10-24 JP JP2010531050A patent/JP2011500811A/ja active Pending
-
2010
- 2010-04-25 IL IL205313A patent/IL205313A0/en unknown
Patent Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH09510470A (ja) * | 1994-03-24 | 1997-10-21 | スミスクライン・ビーチャム・パブリック・リミテッド・カンパニー | ベータ−ラクタム抗生物質およびアルキル硫酸塩の界面活性剤を含有する医薬処方 |
| WO1997010247A1 (en) * | 1995-09-15 | 1997-03-20 | Smithkline Beecham P.L.C. | Clavulanic acid derivatives for treating atherosclerosis |
| US6610681B1 (en) * | 1999-08-16 | 2003-08-26 | Revaax Pharmaceuticals, Llc | Neurotherapeutic clavulanate composition and method |
| US20040014739A1 (en) * | 1999-08-16 | 2004-01-22 | Koppel Gary A. | Neurotherapeutic clavulanate composition and method |
| WO2004071486A1 (en) * | 2003-02-10 | 2004-08-26 | Chemagis Ltd. | Solid amorphous mixtures, processes for the preparation thereof and pharmaceutical compositions containing the same |
| WO2007110875A1 (en) * | 2006-03-24 | 2007-10-04 | Panacea Biotec Ltd. | Antibiotic compositions of modified release and process of production thereof |
Also Published As
| Publication number | Publication date |
|---|---|
| EP2214680A1 (en) | 2010-08-11 |
| EP2214680A4 (en) | 2010-12-29 |
| MX2010004556A (es) | 2010-07-01 |
| US20090270358A1 (en) | 2009-10-29 |
| BRPI0818702A2 (pt) | 2015-04-22 |
| CA2703224A1 (en) | 2009-04-30 |
| WO2009055038A1 (en) | 2009-04-30 |
| CN101918004A (zh) | 2010-12-15 |
| KR20100101574A (ko) | 2010-09-17 |
| IL205313A0 (en) | 2010-12-30 |
| AU2008317315A1 (en) | 2009-04-30 |
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