AU2008279186B2 - Solubility tags for the expression and purification of bioactive peptides - Google Patents

Solubility tags for the expression and purification of bioactive peptides Download PDF

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Publication number
AU2008279186B2
AU2008279186B2 AU2008279186A AU2008279186A AU2008279186B2 AU 2008279186 B2 AU2008279186 B2 AU 2008279186B2 AU 2008279186 A AU2008279186 A AU 2008279186A AU 2008279186 A AU2008279186 A AU 2008279186A AU 2008279186 B2 AU2008279186 B2 AU 2008279186B2
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AU
Australia
Prior art keywords
peptide
seq
interest
inclusion body
fusion
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Ceased
Application number
AU2008279186A
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English (en)
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AU2008279186A1 (en
Inventor
Qiong Cheng
Linda Jane Decarolis
Stephen R. Fahnestock
Tanja Maria Gruber
Lisa Diane Reiss
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EIDP Inc
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EI Du Pont de Nemours and Co
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Publication of AU2008279186A1 publication Critical patent/AU2008279186A1/en
Application granted granted Critical
Publication of AU2008279186B2 publication Critical patent/AU2008279186B2/en
Ceased legal-status Critical Current
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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00Preparation of peptides or proteins
    • C12P21/02Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/90Isomerases (5.)
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • C07K2319/50Fusion polypeptide containing protease site

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  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
AU2008279186A 2007-07-25 2008-07-23 Solubility tags for the expression and purification of bioactive peptides Ceased AU2008279186B2 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US11/782,836 2007-07-25
US11/782,836 US7678883B2 (en) 2007-07-25 2007-07-25 Solubility tags for the expression and purification of bioactive peptides
PCT/US2008/070802 WO2009015165A1 (en) 2007-07-25 2008-07-23 Solubility tags for the expression and purification of bioactive peptides

Publications (2)

Publication Number Publication Date
AU2008279186A1 AU2008279186A1 (en) 2009-01-29
AU2008279186B2 true AU2008279186B2 (en) 2013-09-05

Family

ID=39967949

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2008279186A Ceased AU2008279186B2 (en) 2007-07-25 2008-07-23 Solubility tags for the expression and purification of bioactive peptides

Country Status (10)

Country Link
US (2) US7678883B2 (https=)
EP (1) EP2173877B1 (https=)
JP (1) JP5453261B2 (https=)
KR (1) KR20100057016A (https=)
CN (1) CN101835898B (https=)
AU (1) AU2008279186B2 (https=)
CA (1) CA2689099A1 (https=)
ES (1) ES2439702T3 (https=)
IL (1) IL203002A0 (https=)
WO (1) WO2009015165A1 (https=)

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US7915011B2 (en) * 2009-03-05 2011-03-29 E.I. Du Pont De Nemours And Company Host cell modifications that improve peptide production and downstream processing
US9241987B2 (en) 2009-11-20 2016-01-26 The University Of Chicago Methods and compositions related to immunogenic fibrils
US8609621B2 (en) 2010-11-15 2013-12-17 E I Du Pont De Nemours And Company Acid-cleavable linkers exhibiting altered rates of acid hydrolysis
US9273336B2 (en) 2011-02-21 2016-03-01 E. I. Du Pont De Nemours And Company Recombinant host cells having an increase in buoyant density
US9115182B2 (en) * 2011-06-21 2015-08-25 E I Du Pont De Nemours And Company Cysteine cross-linked structural peptides
US9062312B2 (en) * 2011-06-21 2015-06-23 Danisco Us Inc. Fusion peptides comprising multi-functional peptidic solubility tags for efficient production, processing and surface applications
WO2014056199A1 (zh) * 2012-10-12 2014-04-17 清华大学 多肽的产生和纯化方法
GB201306338D0 (en) 2013-04-08 2013-05-22 Univ Leeds Novel proteoglycans
CN104513298B (zh) * 2014-12-09 2018-07-17 山东信得科技股份有限公司 一种表达鸡传染性法氏囊可溶性vp 2-4-3多肽的方法
JP6640226B2 (ja) * 2014-12-29 2020-02-05 アグリカルチュラル テクノロジー リサーチ インスティテュート 発現エレメント、発現カセット、及びそれらを含むベクター
GB2540763A (en) * 2015-07-24 2017-02-01 Evocatal Gmbh Catalytically active protein aggregates and methods for producing the same
JP7623006B2 (ja) * 2018-09-11 2025-01-28 ナノタグ バイオテクノロジーズ ゲーエムベーハー 特異的結合剤により認識されるエピトープタグ
US20250258180A1 (en) * 2021-07-27 2025-08-14 Stand Therapeutics Co., Ltd. Peptide tag and nucleic acid encoding same
US20250042946A1 (en) 2021-12-08 2025-02-06 Oakgrove Bio Llc Biological Production of Histidine-Rich Peptides
EP4567108A1 (en) * 2023-12-05 2025-06-11 Kutzner, Christoph Screening of target peptides using fusion polypeptides

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WO2004007532A2 (en) * 2002-07-15 2004-01-22 University Of Leeds Beta-sheet forming peptides and material made thereof

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Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2004007532A2 (en) * 2002-07-15 2004-01-22 University Of Leeds Beta-sheet forming peptides and material made thereof

Also Published As

Publication number Publication date
CN101835898A (zh) 2010-09-15
CA2689099A1 (en) 2009-01-29
JP5453261B2 (ja) 2014-03-26
JP2010534477A (ja) 2010-11-11
EP2173877A1 (en) 2010-04-14
EP2173877B1 (en) 2013-10-02
WO2009015165A1 (en) 2009-01-29
AU2008279186A1 (en) 2009-01-29
ES2439702T3 (es) 2014-01-24
US7678883B2 (en) 2010-03-16
US20090029412A1 (en) 2009-01-29
IL203002A0 (en) 2011-08-01
US7794979B2 (en) 2010-09-14
CN101835898B (zh) 2013-01-02
US20100136621A1 (en) 2010-06-03
KR20100057016A (ko) 2010-05-28

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FGA Letters patent sealed or granted (standard patent)
MK14 Patent ceased section 143(a) (annual fees not paid) or expired