AU2008269728B2 - Improving memory in subjects with mini-mental state examination of 24-26 - Google Patents

Improving memory in subjects with mini-mental state examination of 24-26 Download PDF

Info

Publication number
AU2008269728B2
AU2008269728B2 AU2008269728A AU2008269728A AU2008269728B2 AU 2008269728 B2 AU2008269728 B2 AU 2008269728B2 AU 2008269728 A AU2008269728 A AU 2008269728A AU 2008269728 A AU2008269728 A AU 2008269728A AU 2008269728 B2 AU2008269728 B2 AU 2008269728B2
Authority
AU
Australia
Prior art keywords
composition
subject
uridine
vitamin
mini
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
AU2008269728A
Other languages
English (en)
Other versions
AU2008269728A1 (en
Inventor
Anke Bongers
Martine Groenendijk
Patrick Joseph Gerardus Hendrikus Kamphuis
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Nutricia NV
Original Assignee
Nutricia NV
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=41580940&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=AU2008269728(B2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from PCT/NL2007/050307 external-priority patent/WO2009002146A1/en
Priority claimed from PCT/NL2007/050306 external-priority patent/WO2009002145A1/en
Priority claimed from PCT/NL2007/050310 external-priority patent/WO2009002148A1/en
Priority claimed from PCT/NL2008/050124 external-priority patent/WO2009082203A1/en
Application filed by Nutricia NV filed Critical Nutricia NV
Publication of AU2008269728A1 publication Critical patent/AU2008269728A1/en
Application granted granted Critical
Publication of AU2008269728B2 publication Critical patent/AU2008269728B2/en
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/20—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
    • A61K31/202—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids having three or more double bonds, e.g. linolenic
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/115—Fatty acids or derivatives thereof; Fats or oils
    • A23L33/12—Fatty acids or derivatives thereof
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/15—Vitamins
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/16—Inorganic salts, minerals or trace elements
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/40—Complete food formulations for specific consumer groups or specific purposes, e.g. infant formula
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/14—Quaternary ammonium compounds, e.g. edrophonium, choline
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline 
    • A61K31/353—3,4-Dihydrobenzopyrans, e.g. chroman, catechin
    • A61K31/355—Tocopherols, e.g. vitamin E
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/365—Lactones
    • A61K31/375—Ascorbic acid, i.e. vitamin C; Salts thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4415—Pyridoxine, i.e. Vitamin B6
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/557—Eicosanoids, e.g. leukotrienes or prostaglandins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
    • A61K31/706—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
    • A61K31/7064—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines
    • A61K31/7068—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines having oxo groups directly attached to the pyrimidine ring, e.g. cytidine, cytidylic acid
    • A61K31/7072—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines having oxo groups directly attached to the pyrimidine ring, e.g. cytidine, cytidylic acid having two oxo groups directly attached to the pyrimidine ring, e.g. uridine, uridylic acid, thymidine, zidovudine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7135—Compounds containing heavy metals
    • A61K31/714—Cobalamins, e.g. cyanocobalamin, i.e. vitamin B12
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/04—Sulfur, selenium or tellurium; Compounds thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Food Science & Technology (AREA)
  • Mycology (AREA)
  • Polymers & Plastics (AREA)
  • Nutrition Science (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Inorganic Chemistry (AREA)
  • Pediatric Medicine (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
AU2008269728A 2007-06-26 2008-06-20 Improving memory in subjects with mini-mental state examination of 24-26 Active AU2008269728B2 (en)

Applications Claiming Priority (11)

Application Number Priority Date Filing Date Title
PCT/NL2007/050307 WO2009002146A1 (en) 2007-06-26 2007-06-26 Supporting activities of daily living
AUPCT/NL2007/050306 2007-06-26
PCT/NL2007/050306 WO2009002145A1 (en) 2007-06-26 2007-06-26 Lipid composition for improving function of brain functioning
AUPCT/NL2007/050307 2007-06-26
AUPCT/NL2007/050310 2007-06-27
PCT/NL2007/050310 WO2009002148A1 (en) 2007-06-27 2007-06-27 Food composition for prodromal dementia patients
EP07123811 2007-12-20
EP07123811.7 2007-12-20
PCT/NL2008/050124 WO2009082203A1 (en) 2007-12-20 2008-03-04 Liquid nucleotides/nucleosides-containing product
AUPCT/NL2008/050124 2008-03-04
PCT/NL2008/050411 WO2009002166A1 (en) 2007-06-26 2008-06-20 Improving memory in subjects with mini-mental state examination of 24-26

Publications (2)

Publication Number Publication Date
AU2008269728A1 AU2008269728A1 (en) 2008-12-31
AU2008269728B2 true AU2008269728B2 (en) 2013-10-31

Family

ID=41580940

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2008269728A Active AU2008269728B2 (en) 2007-06-26 2008-06-20 Improving memory in subjects with mini-mental state examination of 24-26

Country Status (15)

Country Link
US (3) US20100331258A1 (enExample)
EP (2) EP2170316B1 (enExample)
JP (2) JP5841723B2 (enExample)
CN (2) CN101765427A (enExample)
AU (1) AU2008269728B2 (enExample)
BR (1) BRPI0813770B1 (enExample)
CA (1) CA2692309C (enExample)
DK (1) DK2170316T3 (enExample)
ES (2) ES2445401T3 (enExample)
MX (1) MX2010000224A (enExample)
NZ (2) NZ599748A (enExample)
PL (1) PL2170316T3 (enExample)
PT (1) PT2170316E (enExample)
RU (2) RU2529815C2 (enExample)
WO (1) WO2009002166A1 (enExample)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2009002148A1 (en) * 2007-06-27 2008-12-31 N.V. Nutricia Food composition for prodromal dementia patients
WO2009002146A1 (en) * 2007-06-26 2008-12-31 N.V. Nutricia Supporting activities of daily living
US20100331258A1 (en) 2007-06-26 2010-12-30 N.V. Nutricia memory in subjects with mini-mental state examination of 24-26
WO2009002145A1 (en) 2007-06-26 2008-12-31 N.V. Nutricia Lipid composition for improving function of brain functioning
ES2697149T3 (es) * 2007-12-20 2019-01-22 Nutricia Nv Producto líquido que contiene nucleótidos/nucleósidos
FI3002881T5 (fi) * 2008-02-01 2023-10-04 Järjestelmä ja menetelmä lähtevän siirtotien ajastussynkronointia varten epäjatkuvan vastaanoton yhteydessä
US20130136800A1 (en) * 2010-03-31 2013-05-30 Vegenat, S.A. Enteral Or Oral Food Product Intended, In Particular, For nutrition And For The Prevention And Improvement Of Neurological Alterations, Neurodegenerative Alterations or Cognitive Disorders
WO2012091542A1 (en) * 2010-12-28 2012-07-05 N.V. Nutricia Combination of components for the prevention and treatment of frailty
WO2013066152A1 (en) 2011-10-31 2013-05-10 N.V. Nutricia Method for improving executive function
WO2013066153A1 (en) * 2011-10-31 2013-05-10 N.V. Nutricia Composition for improving neuropsychological test battery score
JP6719860B2 (ja) * 2011-10-31 2020-07-08 エヌ．ブイ．・ヌートリシア 神経心理学的検査バッテリースコアを向上させるための組成物
WO2013066151A1 (en) 2011-10-31 2013-05-10 N.V. Nutricia Improving recognition
US20150044138A1 (en) * 2012-03-02 2015-02-12 N.V. Nutricia Method for improving functional synaptic connectivity
WO2014171813A1 (en) * 2013-04-17 2014-10-23 N.V. Nutricia Nutritional composition for improving brain function in phenylketonuria
WO2015115885A1 (en) 2014-01-31 2015-08-06 N.V. Nutricia Method for reducing white matter lesions, white matter hyperintensities (wmh), leukoaraiosis or periventricular white matter disease in elderly
WO2015115886A1 (en) * 2014-01-31 2015-08-06 N.V. Nutricia Method for treating, stabilizing or slowing down brain glucose metabolism deficit
WO2017069613A1 (en) 2015-10-23 2017-04-27 N.V. Nutricia Method for improving recognition and/or working memory in hyperphenylalanimenia and phenylketonuria patients
WO2017183970A1 (en) * 2016-04-18 2017-10-26 N.V. Nutricia Linoleic acid and alpha-li nolenic acid for use for reducing early-life stress induced cognitive decline/reduction in neurogenesis
CN108567792A (zh) * 2017-03-07 2018-09-25 上海泽生科技开发股份有限公司 一种治疗阿尔茨海默病的复合维生素组合物
US20210128587A1 (en) * 2017-04-11 2021-05-06 Societe Des Produits Nestle S.A. Omega-3 fatty acid and vitamin d levels to identify and attenuate cognitive aging in individuals
WO2022244727A1 (ja) * 2021-05-17 2022-11-24 小野薬品工業株式会社 認知機能を改善するための組成物
WO2023041776A1 (en) 2021-09-17 2023-03-23 N.V. Nutricia Solid composition suitable as a nutritional composition or supplement for animals that suffer from brain related disorders, decline or diseases
US11883457B1 (en) * 2022-09-06 2024-01-30 Optigenex Inc. Method of enhancing cognition in individuals with at least normal cognition

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2003041701A2 (en) * 2001-11-14 2003-05-22 N.V. Nutricia Preparation for improving the action of receptors
EP1666092A2 (en) * 2001-04-30 2006-06-07 Trommsdorff GmbH & Co.KG Arzneimittel Drug combination comprising a fatty acid and a uridine compound.
WO2006127620A2 (en) * 2005-05-23 2006-11-30 Massachusetts Institute Of Technology Compositions containing pufa and methods of use thereof
WO2007073178A2 (en) * 2005-12-23 2007-06-28 N.V. Nutricia Composition comprising polyunsaturated fatty acids, proteins and manganese and/or molybden for improving membrane composition

Family Cites Families (48)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3600197A (en) * 1968-08-27 1971-08-17 Merck & Co Inc Flavor enhancing compositions for foods and beverages
EP0175468A3 (en) 1984-08-10 1987-07-22 Sentrachem Limited Eicosanoids for use in cancer therapy
JP2525624B2 (ja) 1987-09-21 1996-08-21 雪印乳業株式会社 多価不飽和脂肪酸配合育児用粉乳
US5470838A (en) 1987-10-28 1995-11-28 Pro-Neuron, Inc. Method of delivering exogenous uridine or cytidine using acylated uridine or cytidine
JPH06237734A (ja) 1991-11-06 1994-08-30 Sanwa Kagaku Kenkyusho Co Ltd 機能後退性疾患用食品組成物
JPH0717855A (ja) 1992-09-02 1995-01-20 Maruha Corp 脳機能改善組成物、学習能力増強剤、記憶力増強剤、痴呆予防剤、痴呆治療剤、または脳機能改善効果を有する機能性食品
US5378488A (en) * 1993-06-10 1995-01-03 Abbott Laboratories Aseptic processing of infant formula
JP3576318B2 (ja) 1996-06-19 2004-10-13 明治乳業株式会社 核酸関連物質含有栄養組成物
JPH10136937A (ja) 1996-11-08 1998-05-26 Takashi Morita 脳細胞機能向上、血管細胞強化、身体各細胞機能向上栄養総合食品
EP0843972B1 (en) * 1996-11-20 2002-07-31 N.V. Nutricia Nutritional composition comprising fats for the treatment of the metabolic syndrome
EP0891719A1 (en) 1997-07-14 1999-01-20 N.V. Nutricia Nutritional composition containing methionine
JP3731983B2 (ja) * 1997-08-27 2006-01-05 明治製菓株式会社 痴呆犬の夜鳴き改善薬
US8518882B2 (en) * 1998-07-31 2013-08-27 Massachusetts Institute Of Technology Methods and compositions for ameliorating or inhibiting decline in memory or intelligence or improving same
US20070004670A1 (en) * 1998-07-31 2007-01-04 Richard Wurtman Compositions containing citicoline, and methods of use thereof
FR2787799B1 (fr) 1998-12-23 2001-03-09 Rhodia Chimie Sa Composition comprenant une ecorce inorganique et un noyau comportant au moins un compose polyhydroxyle
GB9916536D0 (en) * 1999-07-14 1999-09-15 Scarista Limited Nutritional or pharmaceutical compositions
EP1090636A1 (en) 1999-09-13 2001-04-11 Société des Produits Nestlé S.A. High lipid diet
GB9925709D0 (en) 1999-10-30 1999-12-29 Smithkline Beecham Plc Composition
US6835750B1 (en) * 2000-05-01 2004-12-28 Accera, Inc. Use of medium chain triglycerides for the treatment and prevention of alzheimer's disease and other diseases resulting from reduced neuronal metabolism II
WO2001082928A1 (en) 2000-05-01 2001-11-08 Accera, Inc. Use of medium chain triglycerides for the treatment and prevention of alzheimer's disease and other diseases resulting from reduced neuronal metabolism
US7226916B1 (en) 2000-05-08 2007-06-05 N.V. Nutricia Preparation for the prevention and/or treatment of vascular disorders
US6942874B2 (en) 2001-05-25 2005-09-13 Linguagen Corp. Nucleotide compounds that block the bitter taste of oral compositions
EP1285590A1 (en) 2001-08-08 2003-02-26 Société des Produits Nestlé S.A. Lipid blends
US20030114415A1 (en) * 2001-12-14 2003-06-19 Wurtman Richard J. Compositions and methods for treating and preventing memory impairment using citicoline
US20040001817A1 (en) * 2002-05-14 2004-01-01 Giampapa Vincent C. Anti-aging nutritional supplement
RU2388478C2 (ru) 2003-10-24 2010-05-10 Н.В. Нютрисиа Иммуномодулирующие олигосахариды
US7090879B2 (en) * 2004-03-18 2006-08-15 Abbott Laboratories Nutritional formula containing select carotenoid combinations
AU2005244816B2 (en) * 2004-05-13 2011-09-29 Massachusetts Institute Of Technology Uridine effects on dopamine release
JP2008513453A (ja) * 2004-09-15 2008-05-01 マサチューセッツ インスティテュート オブ テクノロジー ウリジンを含んだ組成物及びその使用方法
EP1656839A1 (en) 2004-11-11 2006-05-17 N.V. Nutricia Nutrition containing lipid blend
US20060252775A1 (en) 2005-05-03 2006-11-09 Henderson Samuel T Methods for reducing levels of disease associated proteins
EP2468273A3 (en) 2005-06-20 2012-07-11 Accera, Inc. Method to reduce oxidative damage and improve mitochondrial efficiency
JP5967855B2 (ja) 2005-06-30 2016-08-10 サントリーホールディングス株式会社 日中活動量の低下および／又はうつ症状の改善作用を有する組成物
JP5697293B2 (ja) 2005-06-30 2015-04-08 サントリーホールディングス株式会社 器質的脳障害に起因する高次脳機能の低下に対する改善作用を有する組成物
KR20180026556A (ko) * 2005-07-08 2018-03-12 디에스엠 아이피 어셋츠 비.브이. 치매 및 치매-전단계와 관련된 용태의 치료를 위한 다중불포화 지방산
WO2007058523A1 (en) * 2005-11-17 2007-05-24 N.V. Nutricia Composition with docosapentaenoic acid
US20070140992A1 (en) * 2005-12-21 2007-06-21 Lynn Schick Taste masking of essential oils using a hydrocolloid
WO2009002148A1 (en) * 2007-06-27 2008-12-31 N.V. Nutricia Food composition for prodromal dementia patients
WO2009002146A1 (en) 2007-06-26 2008-12-31 N.V. Nutricia Supporting activities of daily living
US20100331258A1 (en) 2007-06-26 2010-12-30 N.V. Nutricia memory in subjects with mini-mental state examination of 24-26
WO2009002145A1 (en) 2007-06-26 2008-12-31 N.V. Nutricia Lipid composition for improving function of brain functioning
WO2009057994A1 (en) 2007-11-02 2009-05-07 N.V. Nutricia Unit dosage for brain health
ES2697149T3 (es) 2007-12-20 2019-01-22 Nutricia Nv Producto líquido que contiene nucleótidos/nucleósidos
JP5397321B2 (ja) * 2009-06-09 2014-01-22 株式会社デンソー 駐車支援システム
US8282335B2 (en) 2009-06-12 2012-10-09 Rs Drawings, Llc Liftgate and mounting bracket system
JP5816171B2 (ja) 2009-07-24 2015-11-18 アマゼンティス エスアーＡｍａｚｅｎｔｉｓ Ｓａ 神経変性障害における脳の健康を保護するための化合物、組成物および方法
WO2012091542A1 (en) * 2010-12-28 2012-07-05 N.V. Nutricia Combination of components for the prevention and treatment of frailty
WO2013066151A1 (en) * 2011-10-31 2013-05-10 N.V. Nutricia Improving recognition

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1666092A2 (en) * 2001-04-30 2006-06-07 Trommsdorff GmbH & Co.KG Arzneimittel Drug combination comprising a fatty acid and a uridine compound.
WO2003041701A2 (en) * 2001-11-14 2003-05-22 N.V. Nutricia Preparation for improving the action of receptors
WO2006127620A2 (en) * 2005-05-23 2006-11-30 Massachusetts Institute Of Technology Compositions containing pufa and methods of use thereof
WO2007073178A2 (en) * 2005-12-23 2007-06-28 N.V. Nutricia Composition comprising polyunsaturated fatty acids, proteins and manganese and/or molybden for improving membrane composition

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
Wurtman, Richard J. et al. "Synaptic proteins and phospholipids are increased in gerbil brain by administering uridine plus docosahexaenoic acid orally" Brain Research (2006) Vol.1088 No.1 pages 83 to 92 *

Also Published As

Publication number Publication date
CA2692309C (en) 2016-08-16
BRPI0813770A2 (pt) 2014-12-30
EP2689782B1 (en) 2020-05-13
CA2692309A1 (en) 2008-12-31
BRPI0813770B1 (pt) 2018-05-08
CN104825480A (zh) 2015-08-12
US20200197345A1 (en) 2020-06-25
US20100331258A1 (en) 2010-12-30
MX2010000224A (es) 2010-05-03
US11395810B2 (en) 2022-07-26
NZ599748A (en) 2013-11-29
ES2808406T3 (es) 2021-02-26
JP2014074076A (ja) 2014-04-24
NZ582329A (en) 2012-09-28
BRPI0813770A8 (pt) 2017-06-06
PL2170316T3 (pl) 2014-06-30
RU2677345C2 (ru) 2019-01-16
RU2014122168A (ru) 2015-12-10
JP5934265B2 (ja) 2016-06-15
EP2170316B1 (en) 2013-12-18
RU2529815C2 (ru) 2014-09-27
US20220280466A1 (en) 2022-09-08
DK2170316T3 (en) 2014-02-24
ES2445401T3 (es) 2014-03-03
RU2010102237A (ru) 2011-08-10
JP2010531351A (ja) 2010-09-24
EP2689782A1 (en) 2014-01-29
PT2170316E (pt) 2014-01-30
US12233039B2 (en) 2025-02-25
WO2009002166A1 (en) 2008-12-31
AU2008269728A1 (en) 2008-12-31
CN101765427A (zh) 2010-06-30
EP2170316A1 (en) 2010-04-07
JP5841723B2 (ja) 2016-01-13

Similar Documents

Publication Publication Date Title
US12233039B2 (en) Memory in subjects with mini-mental state examination of 24-26
AU2016202656B2 (en) Combination of components for the prevention and treatment of frailty
AU2012331689B2 (en) Improving recognition
RU2637089C2 (ru) Способ улучшения управляющих функций
WO2009002148A1 (en) Food composition for prodromal dementia patients
US9968629B2 (en) Product and method for supporting uridine homeostasis
AU2012331692A1 (en) Composition for improving neuropsychological test battery score
WO2015160233A1 (en) Method for assessing and treating or preventing impaired plasma polar lipid levels
HK1201743B (en) Method for improving executive function

Legal Events

Date Code Title Description
FGA Letters patent sealed or granted (standard patent)