AU2008262387A1 - IGF for the treatment of Rett Syndrome and synaptic disorders - Google Patents
IGF for the treatment of Rett Syndrome and synaptic disorders Download PDFInfo
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- AU2008262387A1 AU2008262387A1 AU2008262387A AU2008262387A AU2008262387A1 AU 2008262387 A1 AU2008262387 A1 AU 2008262387A1 AU 2008262387 A AU2008262387 A AU 2008262387A AU 2008262387 A AU2008262387 A AU 2008262387A AU 2008262387 A1 AU2008262387 A1 AU 2008262387A1
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Classifications
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- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/30—Insulin-like growth factors, i.e. somatomedins, e.g. IGF-1, IGF-2
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
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- Biomedical Technology (AREA)
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- Psychology (AREA)
- Pain & Pain Management (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Peptides Or Proteins (AREA)
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| PCT/US2008/007107 WO2008153929A1 (en) | 2007-06-08 | 2008-06-06 | Igf for the treatment of rett syndrome and synaptic disorders |
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| AU2008262387A1 true AU2008262387A1 (en) | 2008-12-18 |
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| KR101644250B1 (ko) | 2004-08-23 | 2016-07-29 | 맨카인드 코포레이션 | 약물 전달용 디케토피페라진염, 디케토모르포린염 또는 디케토디옥산염 |
| CN104324362B (zh) | 2005-09-14 | 2018-04-24 | 曼金德公司 | 以提高活性试剂对结晶微粒表面的亲和力为基础的药物配制方法 |
| AU2007238608A1 (en) * | 2006-04-14 | 2007-10-25 | Massachusetts Institute Of Technology | Identifying and modulating molecular pathways that mediate nervous system plasticity |
| TWI614024B (zh) | 2008-08-11 | 2018-02-11 | 曼凱公司 | 超快起作用胰島素之用途 |
| EP2387611A4 (en) | 2009-01-16 | 2012-08-15 | Massachusetts Inst Technology | DIAGNOSIS AND TREATMENT OF AUTISM SPECTRUM DISORDERS |
| EP2571515B1 (en) * | 2010-05-17 | 2016-11-30 | Icahn School of Medicine at Mount Sinai | Methods and assays for treating subjects with shank3 deletion, mutation or reduced expression |
| US9708366B2 (en) | 2011-01-27 | 2017-07-18 | Neuren Pharmaceuticals Ltd. | Treatment of fragile X syndrome using glycyl-L-2-methylprolyl-L-glutamate |
| AU2012236150B2 (en) * | 2011-04-01 | 2016-03-31 | Mannkind Corporation | Blister package for pharmaceutical cartridges |
| WO2013016223A2 (en) * | 2011-07-22 | 2013-01-31 | The University Of Chicago | Treatments for migraine and related disorders |
| BR112014009686A2 (pt) | 2011-10-24 | 2018-08-07 | Mannkind Corp | composição analgésica inalável, pó seco e método para tratar dor |
| AU2013352294A1 (en) * | 2012-11-28 | 2015-07-09 | Neuren Pharmaceuticals Limited | Treatment of Autism Spectrum Disorders using glycyl-l-2-methylprolyl-l-glutamic acid |
| ES2495266B8 (es) * | 2013-02-13 | 2015-11-12 | Consejo Superior De Investigaciones Científicas (Csic) | Uso de igf-1 como reactivo de diagnóstico y/o pronóstico precoz de la enfermedad de alzheimer |
| US10307464B2 (en) | 2014-03-28 | 2019-06-04 | Mannkind Corporation | Use of ultrarapid acting insulin |
| CA2962406A1 (en) | 2014-09-25 | 2016-03-31 | Cold Spring Harbor Laboratory | Treatment of rett syndrome |
| WO2017132127A1 (en) | 2016-01-26 | 2017-08-03 | Anavex Life Sciences Corp. | Neurodevelopmental disorder therapy |
| TWI601821B (zh) * | 2016-04-15 | 2017-10-11 | 中央研究院 | 治療神經發展性疾病 |
| US11331313B2 (en) | 2017-05-22 | 2022-05-17 | Whitehead Institute For Biomedical Research | KCC2 expression enhancing compounds and uses thereof |
| CN108187031A (zh) * | 2018-02-11 | 2018-06-22 | 中国人民解放军第四军医大学 | rhIGF1在制备治疗脆性X综合征药物中的应用 |
| US12324827B2 (en) | 2019-09-09 | 2025-06-10 | The University Of Chicago | Combination therapy for the treatment of migraines |
| WO2021100614A1 (ja) * | 2019-11-19 | 2021-05-27 | 国立大学法人京都大学 | 大豆ペプチド及び／又はコラーゲンペプチド含有神経心理学的機能改善剤 |
| US20230312643A1 (en) * | 2020-09-08 | 2023-10-05 | Sunmarine Biotech | Peptide derivative with collagenase inhibitory activity, and use thereof |
| WO2022165250A1 (en) * | 2021-01-28 | 2022-08-04 | University Of Florida Research Foundation, Incorporated | Treating disorders associated with dyrk1a dysfunction |
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| US4411890A (en) * | 1981-04-14 | 1983-10-25 | Beckman Instruments, Inc. | Synthetic peptides having pituitary growth hormone releasing activity |
| IL71991A (en) * | 1983-06-06 | 1994-05-30 | Genentech Inc | Preparation of human FGI and FGE in their processed form through recombinant AND tranology in prokaryotes |
| AU628322B2 (en) | 1988-01-28 | 1992-09-17 | Eastman Kodak Company | Polypeptide compounds having growth hormone releasing activity |
| AU637316B2 (en) | 1988-01-28 | 1993-05-27 | Eastman Kodak Company | Polypeptide compounds having growth hormone releasing activity |
| SE8803847A0 (sv) | 1988-10-27 | 1990-04-28 | Kabigen Ab | Neuromodulerande peptid |
| US5093317A (en) * | 1989-06-05 | 1992-03-03 | Cephalon, Inc. | Treating disorders by application of insulin-like growth factor |
| US5861373A (en) * | 1991-08-01 | 1999-01-19 | Genentech, Inc | IGF-1 to improve the neural condition |
| EP0597033B1 (en) * | 1991-08-01 | 1997-04-09 | Genentech, Inc. | Igf-1 to improve the neural condition |
| US5420112A (en) * | 1992-06-12 | 1995-05-30 | Lewis; Michael E. | Prevention and treatment of peripheral neuropathy |
| US5446024A (en) * | 1993-12-17 | 1995-08-29 | Genentech, Inc. | Purification of insulin-like growth factor |
| WO1995017204A1 (en) * | 1993-12-23 | 1995-06-29 | Auckland Uniservices Limited | Composition and methods to improve neural outcome |
| US5565428A (en) * | 1995-05-22 | 1996-10-15 | Genentech, Inc. | Method of administration of IGF-I |
| US20030068623A1 (en) * | 1997-06-16 | 2003-04-10 | Genentech, Inc. | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
| US6358951B1 (en) * | 1998-08-21 | 2002-03-19 | Pfizer Inc. | Growth hormone secretagogues |
| EP1109572A4 (en) * | 1998-09-03 | 2004-11-24 | Neuronz Ltd | NEUROPROTECTION |
| AU762351B2 (en) * | 1999-01-06 | 2003-06-26 | Genentech Inc. | Insulin-like growth factor (IGF) I mutant variants |
| AU2001289160A1 (en) | 2000-08-24 | 2002-03-04 | Neuronz Ltd. | Gpe analogs |
| WO2002057241A1 (en) | 2000-12-22 | 2002-07-25 | Bayer Pharmaceuticals Corporation | 8-(AMINOALKOXYMINO)-8H-DIBENZO[a,e]TRIAZOLO[4,5-c]CYCLOHEPTENES AS GROWTH HORMONE SECRETAGOGUES |
| WO2002056873A2 (en) | 2000-12-22 | 2002-07-25 | Bayer Pharmaceuticals Corporation | 2-substituted dibenzo[a,e]1,2,3-triazolo[4,5-c][7]annulen-8-ones as growth hormone secretagogues |
| CN100439397C (zh) * | 2001-02-09 | 2008-12-03 | 基因技术股份有限公司 | Igf-1的结晶 |
| EP1401808B1 (en) * | 2001-05-24 | 2009-07-08 | Neuren Pharmaceuticals Limited | Gpe analogs and peptidomimetics |
| US7863304B2 (en) * | 2001-05-24 | 2011-01-04 | Neuren Pharmaceuticals Limited | Analogs of glycyl-prolyl-glutamate |
| US7485630B2 (en) * | 2003-03-20 | 2009-02-03 | Neuren Pharmaceuticals Limited | Neuroprotective macrocyclic compounds and methods for their use |
| US20050027110A1 (en) | 2003-07-24 | 2005-02-03 | Michael Russell | Drug delivery in the nervous system |
| EP2274978B1 (en) * | 2003-09-12 | 2015-05-20 | Tercica, Inc. | Methods for treatment of insulin-like growth factor-I(IGF-I) deficiency |
| US20070224165A1 (en) * | 2003-10-23 | 2007-09-27 | Neuren Pharmaceuticals Limited | Neuroprotective Effects of Gly-Pro-Glu Following Intravenous Infusion |
| WO2006023530A2 (en) * | 2004-08-16 | 2006-03-02 | Massachusetts Institute Of Technology | Compositions and methods for enhancing structural and functional nervous system reorganization and recovery |
| JP2008511838A (ja) * | 2004-08-30 | 2008-04-17 | テルシカ・インク | インシュリン様成長因子欠乏疾患の診断及び治療のための方法及び装置 |
| KR20060040550A (ko) * | 2004-11-05 | 2006-05-10 | 마루이시세이야쿠가부시키가이샤 | 인슐린유사 성장인자-1 분비촉진제 |
| JP2008545752A (ja) | 2005-06-02 | 2008-12-18 | テルシカ インコーポレーティッド | 成長障害を処置するための方法 |
| AU2007238608A1 (en) * | 2006-04-14 | 2007-10-25 | Massachusetts Institute Of Technology | Identifying and modulating molecular pathways that mediate nervous system plasticity |
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Also Published As
| Publication number | Publication date |
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| US20120177630A1 (en) | 2012-07-12 |
| JP2010529128A (ja) | 2010-08-26 |
| EP2164509A1 (en) | 2010-03-24 |
| WO2008153929A1 (en) | 2008-12-18 |
| CA2689549A1 (en) | 2008-12-18 |
| BRPI0812768A2 (pt) | 2014-12-02 |
| US7994127B2 (en) | 2011-08-09 |
| CN101820896A (zh) | 2010-09-01 |
| US20090099077A1 (en) | 2009-04-16 |
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| MK4 | Application lapsed section 142(2)(d) - no continuation fee paid for the application |