BRPI0812768A2 - Igf para o tratamento de síndrome de rett e transtornos sinápticos. - Google Patents
Igf para o tratamento de síndrome de rett e transtornos sinápticos.Info
- Publication number
- BRPI0812768A2 BRPI0812768A2 BRPI0812768-9A2A BRPI0812768A BRPI0812768A2 BR PI0812768 A2 BRPI0812768 A2 BR PI0812768A2 BR PI0812768 A BRPI0812768 A BR PI0812768A BR PI0812768 A2 BRPI0812768 A2 BR PI0812768A2
- Authority
- BR
- Brazil
- Prior art keywords
- igf
- treatment
- rett syndrome
- synaptic
- disorders
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/30—Insulin-like growth factors, i.e. somatomedins, e.g. IGF-1, IGF-2
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Chemical & Material Sciences (AREA)
- Neurology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Psychiatry (AREA)
- Molecular Biology (AREA)
- Diabetes (AREA)
- Gastroenterology & Hepatology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Zoology (AREA)
- Epidemiology (AREA)
- Immunology (AREA)
- Endocrinology (AREA)
- Hospice & Palliative Care (AREA)
- Psychology (AREA)
- Pain & Pain Management (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US93373807P | 2007-06-08 | 2007-06-08 | |
| PCT/US2008/007107 WO2008153929A1 (en) | 2007-06-08 | 2008-06-06 | Igf for the treatment of rett syndrome and synaptic disorders |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BRPI0812768A2 true BRPI0812768A2 (pt) | 2014-12-02 |
Family
ID=39891784
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BRPI0812768-9A2A BRPI0812768A2 (pt) | 2007-06-08 | 2008-06-06 | Igf para o tratamento de síndrome de rett e transtornos sinápticos. |
Country Status (8)
| Country | Link |
|---|---|
| US (2) | US7994127B2 (cg-RX-API-DMAC7.html) |
| EP (1) | EP2164509A1 (cg-RX-API-DMAC7.html) |
| JP (1) | JP2010529128A (cg-RX-API-DMAC7.html) |
| CN (1) | CN101820896A (cg-RX-API-DMAC7.html) |
| AU (1) | AU2008262387A1 (cg-RX-API-DMAC7.html) |
| BR (1) | BRPI0812768A2 (cg-RX-API-DMAC7.html) |
| CA (1) | CA2689549A1 (cg-RX-API-DMAC7.html) |
| WO (1) | WO2008153929A1 (cg-RX-API-DMAC7.html) |
Families Citing this family (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR101644250B1 (ko) | 2004-08-23 | 2016-07-29 | 맨카인드 코포레이션 | 약물 전달용 디케토피페라진염, 디케토모르포린염 또는 디케토디옥산염 |
| CN104324362B (zh) | 2005-09-14 | 2018-04-24 | 曼金德公司 | 以提高活性试剂对结晶微粒表面的亲和力为基础的药物配制方法 |
| AU2007238608A1 (en) * | 2006-04-14 | 2007-10-25 | Massachusetts Institute Of Technology | Identifying and modulating molecular pathways that mediate nervous system plasticity |
| TWI614024B (zh) | 2008-08-11 | 2018-02-11 | 曼凱公司 | 超快起作用胰島素之用途 |
| EP2387611A4 (en) | 2009-01-16 | 2012-08-15 | Massachusetts Inst Technology | DIAGNOSIS AND TREATMENT OF AUTISM SPECTRUM DISORDERS |
| EP2571515B1 (en) * | 2010-05-17 | 2016-11-30 | Icahn School of Medicine at Mount Sinai | Methods and assays for treating subjects with shank3 deletion, mutation or reduced expression |
| US9708366B2 (en) | 2011-01-27 | 2017-07-18 | Neuren Pharmaceuticals Ltd. | Treatment of fragile X syndrome using glycyl-L-2-methylprolyl-L-glutamate |
| AU2012236150B2 (en) * | 2011-04-01 | 2016-03-31 | Mannkind Corporation | Blister package for pharmaceutical cartridges |
| WO2013016223A2 (en) * | 2011-07-22 | 2013-01-31 | The University Of Chicago | Treatments for migraine and related disorders |
| BR112014009686A2 (pt) | 2011-10-24 | 2018-08-07 | Mannkind Corp | composição analgésica inalável, pó seco e método para tratar dor |
| AU2013352294A1 (en) * | 2012-11-28 | 2015-07-09 | Neuren Pharmaceuticals Limited | Treatment of Autism Spectrum Disorders using glycyl-l-2-methylprolyl-l-glutamic acid |
| ES2495266B8 (es) * | 2013-02-13 | 2015-11-12 | Consejo Superior De Investigaciones Científicas (Csic) | Uso de igf-1 como reactivo de diagnóstico y/o pronóstico precoz de la enfermedad de alzheimer |
| US10307464B2 (en) | 2014-03-28 | 2019-06-04 | Mannkind Corporation | Use of ultrarapid acting insulin |
| CA2962406A1 (en) | 2014-09-25 | 2016-03-31 | Cold Spring Harbor Laboratory | Treatment of rett syndrome |
| WO2017132127A1 (en) | 2016-01-26 | 2017-08-03 | Anavex Life Sciences Corp. | Neurodevelopmental disorder therapy |
| TWI601821B (zh) * | 2016-04-15 | 2017-10-11 | 中央研究院 | 治療神經發展性疾病 |
| US11331313B2 (en) | 2017-05-22 | 2022-05-17 | Whitehead Institute For Biomedical Research | KCC2 expression enhancing compounds and uses thereof |
| CN108187031A (zh) * | 2018-02-11 | 2018-06-22 | 中国人民解放军第四军医大学 | rhIGF1在制备治疗脆性X综合征药物中的应用 |
| US12324827B2 (en) | 2019-09-09 | 2025-06-10 | The University Of Chicago | Combination therapy for the treatment of migraines |
| WO2021100614A1 (ja) * | 2019-11-19 | 2021-05-27 | 国立大学法人京都大学 | 大豆ペプチド及び/又はコラーゲンペプチド含有神経心理学的機能改善剤 |
| US20230312643A1 (en) * | 2020-09-08 | 2023-10-05 | Sunmarine Biotech | Peptide derivative with collagenase inhibitory activity, and use thereof |
| WO2022165250A1 (en) * | 2021-01-28 | 2022-08-04 | University Of Florida Research Foundation, Incorporated | Treating disorders associated with dyrk1a dysfunction |
Family Cites Families (31)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4411890A (en) * | 1981-04-14 | 1983-10-25 | Beckman Instruments, Inc. | Synthetic peptides having pituitary growth hormone releasing activity |
| IL71991A (en) * | 1983-06-06 | 1994-05-30 | Genentech Inc | Preparation of human FGI and FGE in their processed form through recombinant AND tranology in prokaryotes |
| AU628322B2 (en) | 1988-01-28 | 1992-09-17 | Eastman Kodak Company | Polypeptide compounds having growth hormone releasing activity |
| AU637316B2 (en) | 1988-01-28 | 1993-05-27 | Eastman Kodak Company | Polypeptide compounds having growth hormone releasing activity |
| SE8803847A0 (sv) | 1988-10-27 | 1990-04-28 | Kabigen Ab | Neuromodulerande peptid |
| US5093317A (en) * | 1989-06-05 | 1992-03-03 | Cephalon, Inc. | Treating disorders by application of insulin-like growth factor |
| US5861373A (en) * | 1991-08-01 | 1999-01-19 | Genentech, Inc | IGF-1 to improve the neural condition |
| EP0597033B1 (en) * | 1991-08-01 | 1997-04-09 | Genentech, Inc. | Igf-1 to improve the neural condition |
| US5420112A (en) * | 1992-06-12 | 1995-05-30 | Lewis; Michael E. | Prevention and treatment of peripheral neuropathy |
| US5446024A (en) * | 1993-12-17 | 1995-08-29 | Genentech, Inc. | Purification of insulin-like growth factor |
| WO1995017204A1 (en) * | 1993-12-23 | 1995-06-29 | Auckland Uniservices Limited | Composition and methods to improve neural outcome |
| US5565428A (en) * | 1995-05-22 | 1996-10-15 | Genentech, Inc. | Method of administration of IGF-I |
| US20030068623A1 (en) * | 1997-06-16 | 2003-04-10 | Genentech, Inc. | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
| US6358951B1 (en) * | 1998-08-21 | 2002-03-19 | Pfizer Inc. | Growth hormone secretagogues |
| EP1109572A4 (en) * | 1998-09-03 | 2004-11-24 | Neuronz Ltd | NEUROPROTECTION |
| AU762351B2 (en) * | 1999-01-06 | 2003-06-26 | Genentech Inc. | Insulin-like growth factor (IGF) I mutant variants |
| AU2001289160A1 (en) | 2000-08-24 | 2002-03-04 | Neuronz Ltd. | Gpe analogs |
| WO2002057241A1 (en) | 2000-12-22 | 2002-07-25 | Bayer Pharmaceuticals Corporation | 8-(AMINOALKOXYMINO)-8H-DIBENZO[a,e]TRIAZOLO[4,5-c]CYCLOHEPTENES AS GROWTH HORMONE SECRETAGOGUES |
| WO2002056873A2 (en) | 2000-12-22 | 2002-07-25 | Bayer Pharmaceuticals Corporation | 2-substituted dibenzo[a,e]1,2,3-triazolo[4,5-c][7]annulen-8-ones as growth hormone secretagogues |
| CN100439397C (zh) * | 2001-02-09 | 2008-12-03 | 基因技术股份有限公司 | Igf-1的结晶 |
| EP1401808B1 (en) * | 2001-05-24 | 2009-07-08 | Neuren Pharmaceuticals Limited | Gpe analogs and peptidomimetics |
| US7863304B2 (en) * | 2001-05-24 | 2011-01-04 | Neuren Pharmaceuticals Limited | Analogs of glycyl-prolyl-glutamate |
| US7485630B2 (en) * | 2003-03-20 | 2009-02-03 | Neuren Pharmaceuticals Limited | Neuroprotective macrocyclic compounds and methods for their use |
| US20050027110A1 (en) | 2003-07-24 | 2005-02-03 | Michael Russell | Drug delivery in the nervous system |
| EP2274978B1 (en) * | 2003-09-12 | 2015-05-20 | Tercica, Inc. | Methods for treatment of insulin-like growth factor-I(IGF-I) deficiency |
| US20070224165A1 (en) * | 2003-10-23 | 2007-09-27 | Neuren Pharmaceuticals Limited | Neuroprotective Effects of Gly-Pro-Glu Following Intravenous Infusion |
| WO2006023530A2 (en) * | 2004-08-16 | 2006-03-02 | Massachusetts Institute Of Technology | Compositions and methods for enhancing structural and functional nervous system reorganization and recovery |
| JP2008511838A (ja) * | 2004-08-30 | 2008-04-17 | テルシカ・インク | インシュリン様成長因子欠乏疾患の診断及び治療のための方法及び装置 |
| KR20060040550A (ko) * | 2004-11-05 | 2006-05-10 | 마루이시세이야쿠가부시키가이샤 | 인슐린유사 성장인자-1 분비촉진제 |
| JP2008545752A (ja) | 2005-06-02 | 2008-12-18 | テルシカ インコーポレーティッド | 成長障害を処置するための方法 |
| AU2007238608A1 (en) * | 2006-04-14 | 2007-10-25 | Massachusetts Institute Of Technology | Identifying and modulating molecular pathways that mediate nervous system plasticity |
-
2008
- 2008-06-06 CA CA002689549A patent/CA2689549A1/en not_active Abandoned
- 2008-06-06 US US12/134,707 patent/US7994127B2/en active Active
- 2008-06-06 BR BRPI0812768-9A2A patent/BRPI0812768A2/pt not_active IP Right Cessation
- 2008-06-06 AU AU2008262387A patent/AU2008262387A1/en not_active Abandoned
- 2008-06-06 WO PCT/US2008/007107 patent/WO2008153929A1/en not_active Ceased
- 2008-06-06 EP EP08768183A patent/EP2164509A1/en not_active Withdrawn
- 2008-06-06 CN CN200880024937A patent/CN101820896A/zh active Pending
- 2008-06-06 JP JP2010511198A patent/JP2010529128A/ja active Pending
-
2011
- 2011-08-08 US US13/204,817 patent/US20120177630A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| US20120177630A1 (en) | 2012-07-12 |
| JP2010529128A (ja) | 2010-08-26 |
| EP2164509A1 (en) | 2010-03-24 |
| WO2008153929A1 (en) | 2008-12-18 |
| CA2689549A1 (en) | 2008-12-18 |
| AU2008262387A1 (en) | 2008-12-18 |
| US7994127B2 (en) | 2011-08-09 |
| CN101820896A (zh) | 2010-09-01 |
| US20090099077A1 (en) | 2009-04-16 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B08F | Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette] |
Free format text: REFERENTE AS 6A E 7A ANUIDADES. |
|
| B08K | Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette] |
Free format text: EM VIRTUDE DO ARQUIVAMENTO PUBLICADO NA RPI 2329 DE 25-08-2015 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDO O ARQUIVAMENTO DO PEDIDO DE PATENTE, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013. |