AU2008246307A1 - Methods and compositions for the specific inhibition of gene expression by double-stranded RNA - Google Patents

Methods and compositions for the specific inhibition of gene expression by double-stranded RNA Download PDF

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Publication number
AU2008246307A1
AU2008246307A1 AU2008246307A AU2008246307A AU2008246307A1 AU 2008246307 A1 AU2008246307 A1 AU 2008246307A1 AU 2008246307 A AU2008246307 A AU 2008246307A AU 2008246307 A AU2008246307 A AU 2008246307A AU 2008246307 A1 AU2008246307 A1 AU 2008246307A1
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AU
Australia
Prior art keywords
nucleic acid
double stranded
stranded nucleic
strand
oligonucleotide strand
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Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
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AU2008246307A
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English (en)
Inventor
Mark A. Behlke
Dongho Kim
John J. Rossi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Integrated DNA Technologies Inc
City of Hope
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Integrated DNA Technologies Inc
City of Hope
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Filing date
Publication date
Application filed by Integrated DNA Technologies Inc, City of Hope filed Critical Integrated DNA Technologies Inc
Publication of AU2008246307A1 publication Critical patent/AU2008246307A1/en
Priority to AU2014200957A priority Critical patent/AU2014200957A1/en
Abandoned legal-status Critical Current

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    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
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    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
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    • C12N2310/00—Structure or type of the nucleic acid
    • C12N2310/10—Type of nucleic acid
    • C12N2310/14—Type of nucleic acid interfering nucleic acids [NA]
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    • C12N2310/00—Structure or type of the nucleic acid
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    • C12N2310/53—Physical structure partially self-complementary or closed
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    • C12N2320/00—Applications; Uses
    • C12N2320/50—Methods for regulating/modulating their activity
    • C12N2320/51—Methods for regulating/modulating their activity modulating the chemical stability, e.g. nuclease-resistance

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AU2008246307A 2007-05-01 2008-04-11 Methods and compositions for the specific inhibition of gene expression by double-stranded RNA Abandoned AU2008246307A1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2014200957A AU2014200957A1 (en) 2007-05-01 2014-02-24 Methods and compositions for the specific inhibition of gene expression by double-stranded RNA

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US11/797,216 2007-05-01
US11/797,216 US20070265220A1 (en) 2004-03-15 2007-05-01 Methods and compositions for the specific inhibition of gene expression by double-stranded RNA
PCT/US2008/004726 WO2008136902A1 (en) 2007-05-01 2008-04-11 Methods and compositions for the specific inhibition of gene expression by double-stranded rna

Related Child Applications (1)

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AU2014200957A Division AU2014200957A1 (en) 2007-05-01 2014-02-24 Methods and compositions for the specific inhibition of gene expression by double-stranded RNA

Publications (1)

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AU2008246307A1 true AU2008246307A1 (en) 2008-11-13

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AU2008246307A Abandoned AU2008246307A1 (en) 2007-05-01 2008-04-11 Methods and compositions for the specific inhibition of gene expression by double-stranded RNA

Country Status (9)

Country Link
US (11) US20070265220A1 (enExample)
EP (1) EP2155772A4 (enExample)
JP (1) JP2010525813A (enExample)
CN (1) CN101848923A (enExample)
AU (1) AU2008246307A1 (enExample)
BR (1) BRPI0811475A2 (enExample)
CA (1) CA2685453A1 (enExample)
WO (1) WO2008136902A1 (enExample)
ZA (1) ZA200908342B (enExample)

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