AU2007329302A1 - Liquid chromatography detector and flow controller therefor - Google Patents
Liquid chromatography detector and flow controller therefor Download PDFInfo
- Publication number
- AU2007329302A1 AU2007329302A1 AU2007329302A AU2007329302A AU2007329302A1 AU 2007329302 A1 AU2007329302 A1 AU 2007329302A1 AU 2007329302 A AU2007329302 A AU 2007329302A AU 2007329302 A AU2007329302 A AU 2007329302A AU 2007329302 A1 AU2007329302 A1 AU 2007329302A1
- Authority
- AU
- Australia
- Prior art keywords
- flow controller
- set forth
- cross
- degrees
- liquid chromatography
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
- 238000004811 liquid chromatography Methods 0.000 title claims description 35
- 238000001514 detection method Methods 0.000 claims description 43
- 239000006199 nebulizer Substances 0.000 claims description 27
- 238000004458 analytical method Methods 0.000 claims description 12
- 239000007788 liquid Substances 0.000 claims description 8
- 239000012159 carrier gas Substances 0.000 claims description 7
- 230000005465 channeling Effects 0.000 claims description 5
- 238000000034 method Methods 0.000 claims description 3
- 238000000105 evaporative light scattering detection Methods 0.000 description 25
- JYGXADMDTFJGBT-VWUMJDOOSA-N hydrocortisone Chemical compound O=C1CC[C@]2(C)[C@H]3[C@@H](O)C[C@](C)([C@@](CC4)(O)C(=O)CO)[C@@H]4[C@@H]3CCC2=C1 JYGXADMDTFJGBT-VWUMJDOOSA-N 0.000 description 12
- 230000035945 sensitivity Effects 0.000 description 7
- 229960000890 hydrocortisone Drugs 0.000 description 6
- 230000007423 decrease Effects 0.000 description 4
- 239000000443 aerosol Substances 0.000 description 3
- 238000010276 construction Methods 0.000 description 3
- 238000005516 engineering process Methods 0.000 description 3
- 238000001704 evaporation Methods 0.000 description 3
- 230000008020 evaporation Effects 0.000 description 3
- 239000002904 solvent Substances 0.000 description 3
- IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical compound N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 description 2
- 239000000463 material Substances 0.000 description 2
- 230000010355 oscillation Effects 0.000 description 2
- 238000004704 ultra performance liquid chromatography Methods 0.000 description 2
- WEVYAHXRMPXWCK-UHFFFAOYSA-N Acetonitrile Chemical compound CC#N WEVYAHXRMPXWCK-UHFFFAOYSA-N 0.000 description 1
- 238000009825 accumulation Methods 0.000 description 1
- 229910052782 aluminium Inorganic materials 0.000 description 1
- XAGFODPZIPBFFR-UHFFFAOYSA-N aluminium Chemical compound [Al] XAGFODPZIPBFFR-UHFFFAOYSA-N 0.000 description 1
- 239000012491 analyte Substances 0.000 description 1
- 238000000149 argon plasma sintering Methods 0.000 description 1
- 238000004140 cleaning Methods 0.000 description 1
- 150000001875 compounds Chemical class 0.000 description 1
- 230000005494 condensation Effects 0.000 description 1
- 238000009833 condensation Methods 0.000 description 1
- 230000003247 decreasing effect Effects 0.000 description 1
- 230000005684 electric field Effects 0.000 description 1
- 239000007789 gas Substances 0.000 description 1
- 239000011261 inert gas Substances 0.000 description 1
- 238000007689 inspection Methods 0.000 description 1
- 230000007246 mechanism Effects 0.000 description 1
- 229910052751 metal Inorganic materials 0.000 description 1
- 239000002184 metal Substances 0.000 description 1
- 150000002739 metals Chemical class 0.000 description 1
- 229910052757 nitrogen Inorganic materials 0.000 description 1
- 230000003287 optical effect Effects 0.000 description 1
- 239000002245 particle Substances 0.000 description 1
- 229910001220 stainless steel Inorganic materials 0.000 description 1
- 239000010935 stainless steel Substances 0.000 description 1
- 238000011144 upstream manufacturing Methods 0.000 description 1
- 239000002912 waste gas Substances 0.000 description 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
- G01N30/02—Column chromatography
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
- G01N30/02—Column chromatography
- G01N30/62—Detectors specially adapted therefor
- G01N30/74—Optical detectors
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N11/00—Investigating flow properties of materials, e.g. viscosity, plasticity; Analysing materials by determining flow properties
- G01N11/02—Investigating flow properties of materials, e.g. viscosity, plasticity; Analysing materials by determining flow properties by measuring flow of the material
- G01N11/04—Investigating flow properties of materials, e.g. viscosity, plasticity; Analysing materials by determining flow properties by measuring flow of the material through a restricted passage, e.g. tube, aperture
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
- G01N30/02—Column chromatography
- G01N30/84—Preparation of the fraction to be distributed
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
- G01N30/02—Column chromatography
- G01N30/84—Preparation of the fraction to be distributed
- G01N2030/8447—Nebulising, aerosol formation or ionisation
- G01N2030/847—Nebulising, aerosol formation or ionisation by pneumatic means
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
- G01N30/02—Column chromatography
- G01N30/84—Preparation of the fraction to be distributed
- G01N2030/8447—Nebulising, aerosol formation or ionisation
- G01N2030/8494—Desolvation chambers
Landscapes
- Physics & Mathematics (AREA)
- Immunology (AREA)
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pathology (AREA)
- General Physics & Mathematics (AREA)
- Spectroscopy & Molecular Physics (AREA)
- Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
- Flow Control (AREA)
- Treatment Of Liquids With Adsorbents In General (AREA)
- Optical Measuring Cells (AREA)
- Sampling And Sample Adjustment (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US86892406P | 2006-12-06 | 2006-12-06 | |
| US60/868,924 | 2006-12-06 | ||
| PCT/US2007/086640 WO2008070775A2 (en) | 2006-12-06 | 2007-12-06 | Liquid chromatography detector and flow controller therefor |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AU2007329302A1 true AU2007329302A1 (en) | 2008-06-12 |
Family
ID=39493068
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU2007329302A Abandoned AU2007329302A1 (en) | 2006-12-06 | 2007-12-06 | Liquid chromatography detector and flow controller therefor |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US20100288026A1 (https=) |
| EP (1) | EP2087338A4 (https=) |
| JP (1) | JP2010512513A (https=) |
| KR (1) | KR20090106467A (https=) |
| CN (1) | CN101595377A (https=) |
| AU (1) | AU2007329302A1 (https=) |
| BR (1) | BRPI0719924A2 (https=) |
| CA (1) | CA2670828A1 (https=) |
| IL (1) | IL198964A0 (https=) |
| MX (1) | MX2009006058A (https=) |
| NO (1) | NO20092504L (https=) |
| RU (1) | RU2009125589A (https=) |
| WO (1) | WO2008070775A2 (https=) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2319334A1 (en) | 2009-10-27 | 2011-05-11 | Philip Morris Products S.A. | A smoking system having a liquid storage portion |
| CN102593695A (zh) * | 2012-01-18 | 2012-07-18 | 天津市天坤光电技术有限公司 | 一种提高激光晶体棒冷却效率的方法 |
| EP3695208B1 (en) * | 2019-01-02 | 2024-09-18 | Tosoh Corporation | Light scattering detectors and sample cells for the same |
Family Cites Families (28)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3808550A (en) * | 1969-12-15 | 1974-04-30 | Bell Telephone Labor Inc | Apparatuses for trapping and accelerating neutral particles |
| US3894562A (en) * | 1973-12-20 | 1975-07-15 | Jr Charles D Moseley | Fluid flow controller |
| US4426213A (en) * | 1980-11-17 | 1984-01-17 | Engineering Resources, Inc. | Condensate removal device for steam lines and the like |
| JPS62118255A (ja) * | 1985-11-19 | 1987-05-29 | Toshimitsu Musha | 磁界を用いた免疫反応の検出法 |
| US4941618A (en) * | 1986-07-07 | 1990-07-17 | Leeman Labs Inc. | Nebulizer employing a fine mesh screen |
| US5061065A (en) * | 1989-10-20 | 1991-10-29 | Pacific Scientific Company | Particle contamination detection in fluids through the external section of a laser |
| US4958529A (en) * | 1989-11-22 | 1990-09-25 | Vestec Corporation | Interface for coupling liquid chromatography to solid or gas phase detectors |
| JP3087548B2 (ja) * | 1993-12-09 | 2000-09-11 | 株式会社日立製作所 | 液体クロマトグラフ結合型質量分析装置 |
| US5529244A (en) * | 1994-10-04 | 1996-06-25 | S. C. Johnson & Son, Inc. | Aspirator liquid blending device using multiple restrictors |
| US5837826A (en) * | 1995-02-27 | 1998-11-17 | Regents Of The University Of Minnesota | Protein adsorption by very dense porous zirconium oxide particles in expanded beds |
| US5872622A (en) * | 1996-08-12 | 1999-02-16 | Met One, Inc. | Condensation nucleus counter having vapor stabilization and working fluid recovery |
| JPH10162771A (ja) * | 1996-11-28 | 1998-06-19 | Jeol Ltd | 大気圧イオン源 |
| US6362880B1 (en) * | 1997-09-17 | 2002-03-26 | Alltech Associates, Inc. | Low temperature adaptor for evaporative light detection |
| DE19814650C2 (de) * | 1998-04-01 | 2002-02-28 | Aeroquip Vickers Internat Gmbh | Verfahren zur Herstellung einer Drosselstelle in einem Schlauch sowie Drosselstelle in einem Schlauch |
| US6024129A (en) * | 1998-07-16 | 2000-02-15 | Schima; Frank E. | Production efficient venturi insert |
| AU6045400A (en) * | 1999-02-25 | 2000-10-04 | Clemson University | Sampling and analysis of airborne particulate matter by glow discharge atomic emission and mass spectrometries |
| AU4856100A (en) * | 1999-05-17 | 2000-12-05 | Stephen T Flock | Electromagnetic energy driven separation methods |
| US6611780B2 (en) * | 1999-06-09 | 2003-08-26 | Koninklijke Philips Electronics N.V. | System for communicating operational data between an electric toothbrush and a separate control unit |
| US6229605B1 (en) * | 2000-03-10 | 2001-05-08 | Alltech Associates, Inc. | Evaporative light scattering device |
| US20020186263A1 (en) * | 2001-06-07 | 2002-12-12 | Nanostream, Inc. | Microfluidic fraction collectors |
| JP2003222612A (ja) * | 2002-01-30 | 2003-08-08 | Hitachi High-Technologies Corp | 大気圧イオン化質量分析装置および分析方法 |
| US6903818B2 (en) * | 2002-10-28 | 2005-06-07 | Particle Measuring Systems, Inc. | Low noise intracavity laser particle counter |
| GB0304253D0 (en) * | 2003-02-25 | 2003-03-26 | Polymer Lab Ltd | Apparatus |
| US6952013B2 (en) * | 2003-06-06 | 2005-10-04 | Esa Biosciences, Inc. | Electrochemistry with porous flow cell |
| US7114525B2 (en) * | 2003-08-29 | 2006-10-03 | Dana Corporation | Method and apparatus for reduction of fluid-borne noise in hydraulic systems |
| US7268881B2 (en) * | 2004-02-17 | 2007-09-11 | The Curators Of The University Of Missouri | Light scattering detector |
| JP5468206B2 (ja) * | 2005-01-18 | 2014-04-09 | ウオーターズ・テクノロジーズ・コーポレイシヨン | 蒸発光散乱検出器 |
| US7760355B2 (en) * | 2005-07-27 | 2010-07-20 | The Curators Of The University Of Missouri | Focused droplet nebulizer for evaporative light scattering detector |
-
2007
- 2007-12-06 CN CNA2007800450177A patent/CN101595377A/zh active Pending
- 2007-12-06 BR BRPI0719924-4A2A patent/BRPI0719924A2/pt not_active Application Discontinuation
- 2007-12-06 WO PCT/US2007/086640 patent/WO2008070775A2/en not_active Ceased
- 2007-12-06 AU AU2007329302A patent/AU2007329302A1/en not_active Abandoned
- 2007-12-06 JP JP2009540474A patent/JP2010512513A/ja active Pending
- 2007-12-06 RU RU2009125589/28A patent/RU2009125589A/ru not_active Application Discontinuation
- 2007-12-06 CA CA002670828A patent/CA2670828A1/en not_active Abandoned
- 2007-12-06 KR KR1020097011687A patent/KR20090106467A/ko not_active Withdrawn
- 2007-12-06 MX MX2009006058A patent/MX2009006058A/es not_active Application Discontinuation
- 2007-12-06 US US12/517,951 patent/US20100288026A1/en not_active Abandoned
- 2007-12-06 EP EP07854985A patent/EP2087338A4/en not_active Withdrawn
-
2009
- 2009-05-26 IL IL198964A patent/IL198964A0/en unknown
- 2009-07-02 NO NO20092504A patent/NO20092504L/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| WO2008070775A3 (en) | 2008-11-20 |
| IL198964A0 (en) | 2010-02-17 |
| RU2009125589A (ru) | 2011-01-20 |
| US20100288026A1 (en) | 2010-11-18 |
| CA2670828A1 (en) | 2008-06-12 |
| JP2010512513A (ja) | 2010-04-22 |
| EP2087338A2 (en) | 2009-08-12 |
| EP2087338A4 (en) | 2010-04-07 |
| CN101595377A (zh) | 2009-12-02 |
| NO20092504L (no) | 2009-08-12 |
| MX2009006058A (es) | 2009-06-16 |
| BRPI0719924A2 (pt) | 2014-03-04 |
| KR20090106467A (ko) | 2009-10-09 |
| WO2008070775A2 (en) | 2008-06-12 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| US8397553B2 (en) | Liquid chromatography detector and flow controller therefor | |
| JP5240806B2 (ja) | プラズマを用いて試料をイオン化もしくは原子化して分析を行う分析装置用の噴霧器および分析装置 | |
| US20080137065A1 (en) | Measuring Analyte Concentrations in Liquids | |
| Lewis et al. | Electrospray-condensation particle counter: a molecule-counting LC detector for macromolecules | |
| US6229605B1 (en) | Evaporative light scattering device | |
| RU2538364C2 (ru) | Усовершенствованная искровая камера для оптико-эмиссионного анализа | |
| EP3077789B1 (en) | Method and apparatus for online analysis by laser-induced spectroscopy | |
| AU2009325052A1 (en) | Components suitable for use in devices such as an evaporative light scattering detector | |
| KR20220141926A (ko) | 검출기 유입구 및 샘플링 방법 | |
| US20100288026A1 (en) | Liquid chromatography detector and flow controller therefor | |
| US20170341056A1 (en) | GC-FTIR and Mode of Operation to Address Water Interference | |
| WO2012137750A1 (ja) | 長光路長フローセル | |
| US20130269424A1 (en) | Chromatographic Optical Detection System | |
| JP2010512514A5 (https=) | ||
| US20110083493A1 (en) | Liquid Chromatography Detector and Flow Controller Therefor | |
| Hoang et al. | Developments with the oscillating capillary nebulizer—effects of spray chamber design, droplet size and turbulence on analytical signals and analyte transport efficiency of selected biochemically important organoselenium compounds | |
| Gamache et al. | Principles of charged aerosol detection | |
| JP4397396B2 (ja) | レーザ光イオン化装置への直接液体注入口 | |
| US20260021259A1 (en) | Nebulizer spray chamber assembly | |
| JP2010512513A5 (https=) | ||
| JP2002311009A (ja) | クロマトグラフ分取装置 | |
| RU2133024C1 (ru) | Устройство для отбора и концентрирования проб аэрозолей | |
| KR20180075740A (ko) | 나노 입자 분리 및 크기분석을 위한 고감도 분광광도 시스템 | |
| Chaminade | Evaporative Light Scattering and Charged Aerosol Detector | |
| Allen | Aerosol detection in plasma atomic emission spectrometry and condensation nucleation light scattering |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| MK5 | Application lapsed section 142(2)(e) - patent request and compl. specification not accepted |