AU2007245169B2 - Reagents and methods for cancer treatment and prevention - Google Patents

Reagents and methods for cancer treatment and prevention Download PDF

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Publication number
AU2007245169B2
AU2007245169B2 AU2007245169A AU2007245169A AU2007245169B2 AU 2007245169 B2 AU2007245169 B2 AU 2007245169B2 AU 2007245169 A AU2007245169 A AU 2007245169A AU 2007245169 A AU2007245169 A AU 2007245169A AU 2007245169 B2 AU2007245169 B2 AU 2007245169B2
Authority
AU
Australia
Prior art keywords
cells
thapsigargin
cancer cells
cancer
tumor
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
AU2007245169A
Other languages
English (en)
Other versions
AU2007245169A1 (en
Inventor
Dale E. Bredesen
Kayvan R. Niazi
Shahrooz Rabizadeh
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Buck Institute for Research on Aging
Original Assignee
Buck Institute For Age Res
Buck Institute for Research on Aging
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Buck Institute For Age Res, Buck Institute for Research on Aging filed Critical Buck Institute For Age Res
Publication of AU2007245169A1 publication Critical patent/AU2007245169A1/en
Application granted granted Critical
Publication of AU2007245169B2 publication Critical patent/AU2007245169B2/en
Ceased legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • G01N33/502Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing non-proliferative effects
    • G01N33/5023Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing non-proliferative effects on expression patterns
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/365Lactones
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/0005Vertebrate antigens
    • A61K39/0011Cancer antigens
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/51Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/515Animal cells
    • A61K2039/5154Antigen presenting cells [APCs], e.g. dendritic cells or macrophages
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/90Enzymes; Proenzymes
    • G01N2333/902Oxidoreductases (1.)
    • G01N2333/90241Oxidoreductases (1.) acting on single donors with incorporation of molecular oxygen, i.e. oxygenases (1.13)
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2500/00Screening for compounds of potential therapeutic value
    • G01N2500/10Screening for compounds of potential therapeutic value involving cells

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Biomedical Technology (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Oncology (AREA)
  • Mycology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Toxicology (AREA)
  • Biotechnology (AREA)
  • Pathology (AREA)
  • Biochemistry (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Food Science & Technology (AREA)
  • General Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicinal Preparation (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
AU2007245169A 2006-03-27 2007-03-27 Reagents and methods for cancer treatment and prevention Ceased AU2007245169B2 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US11/389,695 US9107863B2 (en) 2006-03-27 2006-03-27 Reagents and methods for cancer treatment and prevention
US11/389,695 2006-03-27
PCT/US2007/007526 WO2007126787A2 (en) 2006-03-27 2007-03-27 Reagents and methods for cancer treatment and prevention

Publications (2)

Publication Number Publication Date
AU2007245169A1 AU2007245169A1 (en) 2007-11-08
AU2007245169B2 true AU2007245169B2 (en) 2012-05-24

Family

ID=38533710

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2007245169A Ceased AU2007245169B2 (en) 2006-03-27 2007-03-27 Reagents and methods for cancer treatment and prevention

Country Status (8)

Country Link
US (4) US9107863B2 (enExample)
EP (2) EP2974738B1 (enExample)
JP (2) JP5422377B2 (enExample)
CN (1) CN101443036A (enExample)
AU (1) AU2007245169B2 (enExample)
CA (1) CA2647542A1 (enExample)
ES (2) ES2655909T3 (enExample)
WO (1) WO2007126787A2 (enExample)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3376495B2 (ja) 1992-08-18 2003-02-10 ソニー株式会社 接着剤の塗布方法及び接着治具
US9107863B2 (en) * 2006-03-27 2015-08-18 The Buck Institute For Age Reasearch Reagents and methods for cancer treatment and prevention
CZ300806B6 (cs) * 2007-07-18 2009-08-12 Ústav experimentální mediciny AV CR, v.v.i. Imunostimulacní úcinky trilobolidu a zpusob jeho prípravy
HK1213740A1 (zh) * 2013-03-15 2016-07-15 Inspyr Therapeutics, Inc. 制备抗癌症组合物的方法
EP2796137A1 (en) * 2013-04-22 2014-10-29 Universität des Saarlandes SERCA inhibitor and Calmodulin antagonist combination
CN112891354B (zh) * 2021-03-18 2022-10-21 新乡医学院 MDM2抑制剂Nutlin-3a在制备激活内质网应激诱导的癌细胞凋亡药物中的应用

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2004037321A2 (en) * 2002-10-25 2004-05-06 University Of Connecticut Health Center Immunotherapy of cancer through controlled cell lysis

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4867973A (en) * 1984-08-31 1989-09-19 Cytogen Corporation Antibody-therapeutic agent conjugates
US4671958A (en) * 1982-03-09 1987-06-09 Cytogen Corporation Antibody conjugates for the delivery of compounds to target sites
IN165717B (enExample) * 1986-08-07 1989-12-23 Battelle Memorial Institute
US5637483A (en) * 1991-10-04 1997-06-10 Whitehead Institute For Biomedical Research Irradiated tumor cell vaccine engineered to express GM-CSF
US5904920A (en) * 1991-10-04 1999-05-18 Whitehead Institute For Biomedical Research Regulation of systemic immune responses utilizing cytokines and antigens
US20010033839A1 (en) * 1999-10-04 2001-10-25 Emilio Barbera-Guillem Vaccine and immunotherapy for solid nonlymphoid tumor and related immune dysregulation
AU5458500A (en) 1999-06-02 2000-12-18 Cell Genesys, Inc. Regulation of systemic immune responses utilizing cytokines and antigens
JP2001010973A (ja) * 1999-06-29 2001-01-16 Dnavec Research Inc がんワクチン
DK1221955T3 (da) * 1999-09-25 2006-01-30 Univ Iowa Res Found Immunstimulerende nukleinsyre
US7056491B2 (en) * 2000-11-08 2006-06-06 Wisconsin Alumni Research Foundation Monoterpenes and sesquiterpenes as chemotherapeutic and radiation sensitizers and immunomodulators
CA2356438A1 (en) * 2001-09-05 2003-03-05 Andre Pichette Use of terpenes and derivatives as potentiators of antitumor agents in the treatment of cancers
WO2003038118A1 (fr) * 2001-10-31 2003-05-08 Fujisawa Pharmaceutical Co., Ltd. Methode d'evaluation d'inhibiteurs de la phosphatase
WO2003087129A2 (en) * 2002-04-08 2003-10-23 Siga Technologies, Inc. Immunogenic peptides, and method of identifying same
EP1689786B1 (en) * 2003-11-30 2014-05-14 Yeda Research And Development Co., Ltd. Methods and agents for immune modulation and methods for identifying immune modulators
US9107863B2 (en) 2006-03-27 2015-08-18 The Buck Institute For Age Reasearch Reagents and methods for cancer treatment and prevention

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2004037321A2 (en) * 2002-10-25 2004-05-06 University Of Connecticut Health Center Immunotherapy of cancer through controlled cell lysis

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
DENMEADE, S.R. et al. Journal of the National Cancer Institute. 2003. 95(13): 990-1000 *
LOWRY, D.T et al. Carcinogenesis, 1996. 17(4): 699-706 *

Also Published As

Publication number Publication date
US20180128816A1 (en) 2018-05-10
EP2004219A4 (en) 2010-06-30
EP2004219B1 (en) 2015-09-16
JP2014028815A (ja) 2014-02-13
US9885704B2 (en) 2018-02-06
CN101443036A (zh) 2009-05-27
WO2007126787A2 (en) 2007-11-08
US20100278874A1 (en) 2010-11-04
EP2974738A1 (en) 2016-01-20
AU2007245169A1 (en) 2007-11-08
EP2974738B1 (en) 2017-11-15
US20160069864A1 (en) 2016-03-10
JP2009535298A (ja) 2009-10-01
EP2004219A2 (en) 2008-12-24
US20070224207A1 (en) 2007-09-27
JP5712257B2 (ja) 2015-05-07
ES2655909T3 (es) 2018-02-22
CA2647542A1 (en) 2007-11-08
JP5422377B2 (ja) 2014-02-19
US9107863B2 (en) 2015-08-18
ES2548435T3 (es) 2015-10-16
WO2007126787A3 (en) 2008-10-23
US8895031B2 (en) 2014-11-25

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FGA Letters patent sealed or granted (standard patent)
MK14 Patent ceased section 143(a) (annual fees not paid) or expired