AU2007208223A1 - Methods and compositions for treating schizophrenia - Google Patents

Methods and compositions for treating schizophrenia Download PDF

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Publication number
AU2007208223A1
AU2007208223A1 AU2007208223A AU2007208223A AU2007208223A1 AU 2007208223 A1 AU2007208223 A1 AU 2007208223A1 AU 2007208223 A AU2007208223 A AU 2007208223A AU 2007208223 A AU2007208223 A AU 2007208223A AU 2007208223 A1 AU2007208223 A1 AU 2007208223A1
Authority
AU
Australia
Prior art keywords
indole
pyrido
schizophrenia
tetrahydro
methyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2007208223A
Other languages
English (en)
Other versions
AU2007208223A8 (en
Inventor
Sergei O. Bachurin
Allan G. Beniashvili
Vladimir V. Grigoriev
Margarita A. Morozova
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Medivation Neurology Inc
Original Assignee
Medivation LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Medivation LLC filed Critical Medivation LLC
Publication of AU2007208223A1 publication Critical patent/AU2007208223A1/en
Publication of AU2007208223A8 publication Critical patent/AU2007208223A8/en
Abandoned legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/437—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a five-membered ring having nitrogen as a ring hetero atom, e.g. indolizine, beta-carboline
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/444—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a six-membered ring with nitrogen as a ring heteroatom, e.g. amrinone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Psychiatry (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
AU2007208223A 2006-01-25 2007-01-25 Methods and compositions for treating schizophrenia Abandoned AU2007208223A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
RU2006101999/15A RU2338537C2 (ru) 2006-01-25 2006-01-25 СРЕДСТВО ДЛЯ ЛЕЧЕНИЯ ШИЗОФРЕНИИ НА ОСНОВЕ ГИДРИРОВАННЫХ ПИРИДО(4,3-b)ИНДОЛОВ (ВАРИАНТЫ), ФАРМАКОЛОГИЧЕСКОЕ СРЕДСТВО НА ЕГО ОСНОВЕ И СПОСОБ ЕГО ПРИМЕНЕНИЯ
RU2006101999 2006-01-25
PCT/US2007/002117 WO2007087425A1 (en) 2006-01-25 2007-01-25 Methods and compositions for treating schizophrenia

Publications (2)

Publication Number Publication Date
AU2007208223A1 true AU2007208223A1 (en) 2007-08-02
AU2007208223A8 AU2007208223A8 (en) 2008-09-18

Family

ID=37946164

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2007208223A Abandoned AU2007208223A1 (en) 2006-01-25 2007-01-25 Methods and compositions for treating schizophrenia

Country Status (8)

Country Link
US (1) US20070225316A1 (https=)
EP (1) EP1976518A1 (https=)
JP (2) JP2009524676A (https=)
AU (1) AU2007208223A1 (https=)
CA (1) CA2640223A1 (https=)
IL (1) IL193014A0 (https=)
RU (1) RU2338537C2 (https=)
WO (1) WO2007087425A1 (https=)

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RU2007139634A (ru) 2007-10-25 2009-04-27 Сергей Олегович Бачурин (RU) Новые тиазол-, триазол- или оксадиазол-содержащие тетрациклические соединения
RU2544856C2 (ru) * 2008-01-25 2015-03-20 Сергей Олегович Бачурин НОВЫЕ ПРОИЗВОДНЫЕ 2,3,4,5-ТЕТРАГИДРО-1-ПИРИДО[4,3-b]ИНДОЛА И СПОСОБЫ ИХ ПРИМЕНЕНИЯ
JP5666036B2 (ja) * 2008-01-25 2015-02-04 メディベイション テクノロジーズ， インコーポレイテッド 新規２，３，４，５−テトラヒドロ−１Ｈ−ピリド［４，３−ｂ］インドール化合物およびその使用方法
TWI498328B (zh) * 2008-01-25 2015-09-01 Medivation Technologies Inc 新穎之２，３，４，５－四氫－１ｈ－吡啶并〔４，３－ｂ〕吲哚化合物及其使用方法
WO2009111540A1 (en) * 2008-03-04 2009-09-11 Medivation Neurology, Inc. Methods for preparing pyridylethyl-substituted carbolines
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WO2009120717A2 (en) 2008-03-24 2009-10-01 Medivation Technologies, Inc. Pyrido [3, 4-b] indoles and methods of use
RU2374245C1 (ru) * 2008-08-22 2009-11-27 Андрей Александрович Иващенко Лиганд с широким спектром одновременной рецепторной активности, фармацевтическая композиция, способ ее получения и лекарственное средство
AU2009308708B2 (en) 2008-10-31 2015-11-19 Medivation Technologies, Inc. Azepino [4, 5-b] indoles and methods of use
TWI477503B (zh) * 2008-10-31 2015-03-21 Medivation Technologies Inc 含有剛性部分之吡啶并〔４，３－ｂ〕吲哚
CA2748813C (en) 2009-01-09 2018-07-10 Board Of Regents Of The University Of Texas System Pro-neurogenic compounds
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CA2775328A1 (en) 2009-09-23 2011-03-31 Medivation Technologies, Inc. Pyrido[4,3-b]indoles and methods of use
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US9079904B2 (en) 2009-09-23 2015-07-14 Medivation Technologies, Inc. Pyrido[3,4-B]indoles and methods of use
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RU2425046C1 (ru) * 2009-12-04 2011-07-27 Сергей Олегович Бачурин АНТИДЕПРЕССИВНОЕ И ПРОТИВОГИПОКСИЧЕСКОЕ СРЕДСТВО НА ОСНОВЕ СОЛЕЙ 2,8-ДИМЕТИЛ-5-[2-(6-МЕТИЛ-ПИРИДИЛ-3)ЭТИЛ]-2,3,4,5-ТЕТРАГИДРО-1Н-ПИРИДО[4,3-b]ИНДОЛА И ФАРМАЦЕВТИЧЕСКАЯ КОМПОЗИЦИЯ НА ИХ ОСНОВЕ
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US8791132B2 (en) 2011-02-18 2014-07-29 Medivation Technologies, Inc. Compounds and methods for treatment of hypertension
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US9434747B2 (en) 2011-02-18 2016-09-06 Medivation Technologies, Inc. Methods of treating diabetes
RU2477131C1 (ru) * 2012-01-17 2013-03-10 Алиса Владимировна Алесенко СРЕДСТВО ДЛЯ НЕЙТРАЛИЗАЦИИ ТОКСИЧЕСКОГО ДЕЙСТВИЯ ФАКТОРА НЕКРОЗА ОПУХОЛИ НА ОСНОВЕ ГИДРИРОВАННЫХ ПИРИДО (4,3-b) ИНДОЛОВ, ФАРМАКОЛОГИЧЕСКОЕ СРЕДСТВО НА ЕГО ОСНОВЕ И СПОСОБ ЛЕЧЕНИЯ АУТОИММУННЫХ ЗАБОЛЕВАНИЙ НА ОСНОВЕ НЕЙТРАЛИЗАЦИИ ТОКСИЧЕСКОГО ДЕЙСТВИЯ ФАКТОРА НЕКРОЗА ОПУХОЛИ
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Also Published As

Publication number Publication date
JP2009524676A (ja) 2009-07-02
US20070225316A1 (en) 2007-09-27
IL193014A0 (en) 2009-08-03
AU2007208223A8 (en) 2008-09-18
JP2010116412A (ja) 2010-05-27
EP1976518A1 (en) 2008-10-08
WO2007087425A1 (en) 2007-08-02
RU2006101999A (ru) 2007-08-10
CA2640223A1 (en) 2007-08-02
RU2338537C2 (ru) 2008-11-20

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Free format text: IN VOL 22, NO 34, PAGE(S) 4044 UNDER THE HEADING PCT APPLICATIONS THAT HAVE ENTERED THE NATIONAL PHASE -NAME INDEX UNDER THE NAME MEDIVATION, INC., APPLICATION NO. 2007208223, UNDER INID (71), CORRECT THE NAME TO READ MEDIVATION NEUROLOGY, INC.

MK1 Application lapsed section 142(2)(a) - no request for examination in relevant period