AU2007208151B2 - Vinyl-phenyl derivatives for inflammation and immune-related uses - Google Patents
Vinyl-phenyl derivatives for inflammation and immune-related uses Download PDFInfo
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- AU2007208151B2 AU2007208151B2 AU2007208151A AU2007208151A AU2007208151B2 AU 2007208151 B2 AU2007208151 B2 AU 2007208151B2 AU 2007208151 A AU2007208151 A AU 2007208151A AU 2007208151 A AU2007208151 A AU 2007208151A AU 2007208151 B2 AU2007208151 B2 AU 2007208151B2
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- optionally substituted
- phenyl
- methyl
- compound
- difluoro
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Families Citing this family (84)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9123077B2 (en) | 2003-10-07 | 2015-09-01 | Hospira, Inc. | Medication management system |
| US8065161B2 (en) | 2003-11-13 | 2011-11-22 | Hospira, Inc. | System for maintaining drug information and communicating with medication delivery devices |
| JP2009528273A (ja) * | 2006-01-25 | 2009-08-06 | シンタ ファーマシューティカルズ コーポレーション | 炎症および免疫関連使用用の置換ビアリール化合物 |
| JP2009524677A (ja) * | 2006-01-25 | 2009-07-02 | シンタ ファーマシューティカルズ コーポレーション | 炎症および免疫関連使用用のチアゾールおよびチアジアゾール化合物 |
| CA2639913A1 (en) * | 2006-01-25 | 2007-08-02 | Synta Pharmaceutical Corp. | Phenyl and pyridyl compounds for inflammation and immune-related uses |
| CA2640090A1 (en) * | 2006-01-25 | 2007-08-02 | Synta Pharmaceuticals Corp. | Substituted aromatic compounds for inflammation and immune-related uses |
| CA2645434A1 (en) | 2006-03-20 | 2007-09-27 | Synta Pharmaceutical Corp. | Benzoimidazolyl-parazine compounds for inflammation and immune-related uses |
| US8779154B2 (en) * | 2006-09-26 | 2014-07-15 | Qinglin Che | Fused ring compounds for inflammation and immune-related uses |
| WO2008057729A2 (en) | 2006-10-16 | 2008-05-15 | Hospira, Inc. | System and method for comparing and utilizing activity information and configuration information from mulitple device management systems |
| EP2086326B1 (en) * | 2006-11-13 | 2014-01-08 | Synta Pharmaceuticals Corp. | Cyclohexenyl-aryl compounds for inflammation and immune-related uses |
| JP5330260B2 (ja) | 2006-12-06 | 2013-10-30 | スミスクライン ビーチャム コーポレーション | 二環式化合物ならびに抗糖尿病薬としての使用 |
| CL2008001933A1 (es) * | 2007-06-29 | 2009-09-25 | Millennium Pharm Inc | Compuestos derivados de pirimidina, inhibidores de la raf quinasa; compuestos intermediarios; procedimiento de preparacion; composicion farmaceutica; y su uso para tratar trastornos proliferativos, cardiacos, neurodegenerativos, inflamatorios, oseos, inmunologicos enfermedad viral, entre otros. |
| EP2185514A4 (en) * | 2007-08-01 | 2011-05-18 | Synta Pharmaceuticals Corp | VINYL-ARYL DERIVATIVES FOR INFLAMMATORY AND IMMUNE DISORDERS |
| RU2465272C2 (ru) | 2007-09-10 | 2012-10-27 | КалсиМедика, Инк. | Соединения, моделирующие внутриклеточный кальций |
| WO2009076454A2 (en) * | 2007-12-12 | 2009-06-18 | Calcimedica, Inc. | Compounds that modulate intracellular calcium |
| US8517990B2 (en) | 2007-12-18 | 2013-08-27 | Hospira, Inc. | User interface improvements for medical devices |
| CA2734500A1 (en) | 2008-08-27 | 2010-03-11 | Calcimedica Inc. | Compounds that modulate intracellular calcium |
| US8524763B2 (en) * | 2008-09-22 | 2013-09-03 | Calcimedica, Inc. | Inhibitors of store operated calcium release |
| WO2010039236A1 (en) * | 2008-10-01 | 2010-04-08 | Synta Pharmaceuticals Corp. | Compounds for inflammation and immune-related uses |
| US8143269B2 (en) * | 2008-10-03 | 2012-03-27 | Calcimedica, Inc. | Inhibitors of store operated calcium release |
| US8271106B2 (en) | 2009-04-17 | 2012-09-18 | Hospira, Inc. | System and method for configuring a rule set for medical event management and responses |
| CN102438452B (zh) * | 2009-05-08 | 2015-02-25 | 乔治亚州大学研究基金会 | 包含cdk抑制剂的化合物和组合物以及用于癌症治疗的方法 |
| US8618307B2 (en) * | 2009-09-16 | 2013-12-31 | Calcimedica, Inc. | Compounds that modulate intracellular calcium |
| US8993612B2 (en) | 2009-10-08 | 2015-03-31 | Rhizen Pharmaceuticals Sa | Modulators of calcium release-activated calcium channel and methods for treatment of non-small cell lung cancer |
| US8377970B2 (en) | 2009-10-08 | 2013-02-19 | Rhizen Pharmaceuticals Sa | Modulators of calcium release-activated calcium channel |
| EP2532656A1 (en) * | 2010-02-01 | 2012-12-12 | Nippon Chemiphar Co., Ltd. | Gpr119 agonist |
| JP6112486B2 (ja) | 2010-04-27 | 2017-04-12 | カルシメディカ,インク. | 細胞内カルシウムを調節する化合物 |
| US10703722B2 (en) | 2010-04-27 | 2020-07-07 | Calcimedica, Inc. | Compounds that modulate intracellular calcium |
| EP2563759B1 (en) | 2010-04-27 | 2022-04-06 | Calcimedica, Inc. | Compounds that modulate intracellular calcium |
| CN103180316A (zh) | 2010-08-27 | 2013-06-26 | 钙医学公司 | 调节细胞内钙的化合物 |
| KR20140000695A (ko) * | 2010-10-14 | 2014-01-03 | 미쓰비시 타나베 파마 코퍼레이션 | 아미드 유도체 및 그 용도 |
| WO2012170931A2 (en) | 2011-06-10 | 2012-12-13 | Calcimedica, Inc. | Compounds that modulate intracellular calcium |
| US9240002B2 (en) | 2011-08-19 | 2016-01-19 | Hospira, Inc. | Systems and methods for a graphical interface including a graphical representation of medical data |
| WO2013059677A1 (en) | 2011-10-19 | 2013-04-25 | Calcimedica, Inc. | Compounds that modulate intracellular calcium |
| WO2013059615A1 (en) | 2011-10-21 | 2013-04-25 | Hospira, Inc. | Medical device update system |
| US20140242099A1 (en) * | 2011-10-28 | 2014-08-28 | Synta Pharmaceuticals Corp. | Compounds for inflammation and immune-related uses |
| US10022498B2 (en) | 2011-12-16 | 2018-07-17 | Icu Medical, Inc. | System for monitoring and delivering medication to a patient and method of using the same to minimize the risks associated with automated therapy |
| EP2830687B1 (en) | 2012-03-30 | 2019-07-24 | ICU Medical, Inc. | Air detection system and method for detecting air in a pump of an infusion system |
| AU2013296555B2 (en) | 2012-07-31 | 2017-10-19 | Icu Medical, Inc. | Patient care system for critical medications |
| WO2014059333A1 (en) | 2012-10-12 | 2014-04-17 | Calcimedica, Inc. | Compounds that modulate intracellular calcium |
| EP2964079B1 (en) | 2013-03-06 | 2022-02-16 | ICU Medical, Inc. | Medical device communication method |
| US10046112B2 (en) | 2013-05-24 | 2018-08-14 | Icu Medical, Inc. | Multi-sensor infusion system for detecting air or an occlusion in the infusion system |
| AU2014274122A1 (en) | 2013-05-29 | 2016-01-21 | Icu Medical, Inc. | Infusion system and method of use which prevents over-saturation of an analog-to-digital converter |
| WO2014194089A1 (en) | 2013-05-29 | 2014-12-04 | Hospira, Inc. | Infusion system which utilizes one or more sensors and additional information to make an air determination regarding the infusion system |
| US20150066531A1 (en) | 2013-08-30 | 2015-03-05 | James D. Jacobson | System and method of monitoring and managing a remote infusion regimen |
| US9662436B2 (en) | 2013-09-20 | 2017-05-30 | Icu Medical, Inc. | Fail-safe drug infusion therapy system |
| US10311972B2 (en) | 2013-11-11 | 2019-06-04 | Icu Medical, Inc. | Medical device system performance index |
| CA2930830C (en) | 2013-11-19 | 2019-12-03 | Hospira, Inc. | Infusion pump automation system and method |
| ES2776363T3 (es) | 2014-02-28 | 2020-07-30 | Icu Medical Inc | Sistema de infusión y método que utiliza detección óptica de aire en línea de doble longitud de onda |
| JP6853669B2 (ja) | 2014-04-30 | 2021-03-31 | アイシーユー・メディカル・インコーポレーテッド | 条件付きの警報転送を用いた患者治療システム |
| US11344673B2 (en) | 2014-05-29 | 2022-05-31 | Icu Medical, Inc. | Infusion system and pump with configurable closed loop delivery rate catch-up |
| US9724470B2 (en) | 2014-06-16 | 2017-08-08 | Icu Medical, Inc. | System for monitoring and delivering medication to a patient and method of using the same to minimize the risks associated with automated therapy |
| US9539383B2 (en) | 2014-09-15 | 2017-01-10 | Hospira, Inc. | System and method that matches delayed infusion auto-programs with manually entered infusion programs and analyzes differences therein |
| US11344668B2 (en) | 2014-12-19 | 2022-05-31 | Icu Medical, Inc. | Infusion system with concurrent TPN/insulin infusion |
| TWI771269B (zh) | 2015-02-27 | 2022-07-21 | 美商鈣系醫藥公司 | 胰腺炎治療 |
| US10850024B2 (en) | 2015-03-02 | 2020-12-01 | Icu Medical, Inc. | Infusion system, device, and method having advanced infusion features |
| CN107847548B (zh) | 2015-05-18 | 2022-06-14 | 贝思以色列女会吏医学中心公司 | P物质、肥大细胞脱颗粒抑制剂和周围神经病 |
| ES2845725T3 (es) | 2015-05-26 | 2021-07-27 | Icu Medical Inc | Sistema y método de bomba de infusión con capacidad de fuente de editor de múltiples bibliotecas de fármacos |
| CA2995094A1 (en) | 2015-08-07 | 2017-02-16 | Calcimedica, Inc. | Use of crac channel inhibitors for the treatment of stroke and traumatic brain injury |
| ES2912378T3 (es) | 2016-05-13 | 2022-05-25 | Icu Medical Inc | Sistema de bomba de infusión con purga automática de línea común |
| AU2017277804B2 (en) | 2016-06-10 | 2022-05-26 | Icu Medical, Inc. | Acoustic flow sensor for continuous medication flow measurements and feedback control of infusion |
| AU2017295722B2 (en) | 2016-07-14 | 2022-08-11 | Icu Medical, Inc. | Multi-communication path selection and security system for a medical device |
| US20180047567A1 (en) * | 2016-08-09 | 2018-02-15 | Samsung Electronics Co., Ltd. | Method of fabricating thin film |
| US10089055B1 (en) | 2017-12-27 | 2018-10-02 | Icu Medical, Inc. | Synchronized display of screen content on networked devices |
| ES2985889T3 (es) | 2018-07-17 | 2024-11-07 | Icu Medical Inc | Actualización de las bibliotecas de fármacos de bombas de infusión y software operacional en un entorno en red |
| EP4297379B1 (en) | 2018-07-17 | 2026-04-01 | ICU Medical, Inc. | Systems and methods for facilitating clinical messaging in a network environment |
| AU2019309766B2 (en) | 2018-07-26 | 2024-06-13 | Icu Medical, Inc. | Drug library management system |
| JP2022508468A (ja) | 2018-09-14 | 2022-01-19 | ルヒゼン ファーマスティカルズ アクツィエンゲゼルシャフト | Crac阻害剤およびコルチコステロイドを含む組成物ならびにそれらの使用方法 |
| AU2019387370A1 (en) | 2018-11-30 | 2021-06-10 | Nuvation Bio Inc. | Pyrrole and pyrazole compounds and methods of use thereof |
| EP3966992A4 (en) | 2019-05-08 | 2023-06-21 | ICU Medical, Inc. | THRESHOLD SIGNATURE BASED MEDICAL DEVICE MANAGEMENT |
| TW202116754A (zh) | 2019-07-11 | 2021-05-01 | 美商E 斯蓋普生物股份有限公司 | 作為lrrk2抑制劑之吲唑及氮雜吲唑 |
| US11278671B2 (en) | 2019-12-04 | 2022-03-22 | Icu Medical, Inc. | Infusion pump with safety sequence keypad |
| US12486274B2 (en) | 2020-01-13 | 2025-12-02 | Verge Analytics, Inc. | Substituted pyrazolo-pyrimidines and uses thereof |
| CA3172249A1 (en) | 2020-03-20 | 2021-09-23 | Calcimedica, Inc. | Methods and compositions for treating acute lung injury and acute respiratory distress syndrome |
| US11590057B2 (en) | 2020-04-03 | 2023-02-28 | Icu Medical, Inc. | Systems, methods, and components for transferring medical fluids |
| CN113717116A (zh) * | 2020-05-25 | 2021-11-30 | 上海医药工业研究院 | 一种环戊烯类化合物、其制备方法及应用 |
| CA3187817A1 (en) | 2020-07-02 | 2022-01-06 | Icu Medical, Inc. | Location-based reconfiguration of infusion pump settings |
| CA3189781A1 (en) | 2020-07-21 | 2022-01-27 | Icu Medical, Inc. | Fluid transfer devices and methods of use |
| EP4208798A4 (en) | 2020-09-05 | 2024-10-09 | ICU Medical, Inc. | IDENTITY-BASED SECURE COMMUNICATION OF MEDICAL DEVICES |
| JP7791898B2 (ja) | 2020-11-13 | 2025-12-24 | カルシメディカ,インク. | Cracチャネル阻害剤の合成の改善 |
| US11135360B1 (en) | 2020-12-07 | 2021-10-05 | Icu Medical, Inc. | Concurrent infusion with common line auto flush |
| US12599716B2 (en) | 2021-10-12 | 2026-04-14 | Icu Medical, Inc. | Intravenous infusion pump with cassette insertion and pump control user interface |
| USD1091564S1 (en) | 2021-10-13 | 2025-09-02 | Icu Medical, Inc. | Display screen or portion thereof with graphical user interface for a medical device |
| WO2023108030A1 (en) | 2021-12-10 | 2023-06-15 | Icu Medical, Inc. | Medical fluid compounding systems with coordinated flow control |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5449687A (en) * | 1992-04-02 | 1995-09-12 | Smithkline Beecham Corporation | 4-phenyl-1,2-cyclohexyl derivatives and anti-inflammatory compositions and methods thereof |
| US6348480B1 (en) * | 1997-10-13 | 2002-02-19 | Yamanouchi Pharmaceutical Co., Ltd. | Pharmaceutical compound comprising a pyrazole derivative and methods of using the same for the treatment of calcium release-activated calcium channel associated diseases |
| US20040014971A1 (en) * | 2000-09-04 | 2004-01-22 | Lieven Meerpoel | Polyarylcarboxamides useful as lipid lowering agents |
Family Cites Families (47)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3536809A (en) | 1969-02-17 | 1970-10-27 | Alza Corp | Medication method |
| US3598123A (en) | 1969-04-01 | 1971-08-10 | Alza Corp | Bandage for administering drugs |
| US3845770A (en) | 1972-06-05 | 1974-11-05 | Alza Corp | Osmatic dispensing device for releasing beneficial agent |
| US3916899A (en) | 1973-04-25 | 1975-11-04 | Alza Corp | Osmotic dispensing device with maximum and minimum sizes for the passageway |
| US4008719A (en) | 1976-02-02 | 1977-02-22 | Alza Corporation | Osmotic system having laminar arrangement for programming delivery of active agent |
| IE58110B1 (en) | 1984-10-30 | 1993-07-14 | Elan Corp Plc | Controlled release powder and process for its preparation |
| US5073543A (en) | 1988-07-21 | 1991-12-17 | G. D. Searle & Co. | Controlled release formulations of trophic factors in ganglioside-lipsome vehicle |
| IT1229203B (it) | 1989-03-22 | 1991-07-25 | Bioresearch Spa | Impiego di acido 5 metiltetraidrofolico, di acido 5 formiltetraidrofolico e dei loro sali farmaceuticamente accettabili per la preparazione di composizioni farmaceutiche in forma a rilascio controllato attive nella terapia dei disturbi mentali organici e composizioni farmaceutiche relative. |
| US5120548A (en) | 1989-11-07 | 1992-06-09 | Merck & Co., Inc. | Swelling modulated polymeric drug delivery device |
| US5733566A (en) | 1990-05-15 | 1998-03-31 | Alkermes Controlled Therapeutics Inc. Ii | Controlled release of antiparasitic agents in animals |
| US5580578A (en) | 1992-01-27 | 1996-12-03 | Euro-Celtique, S.A. | Controlled release formulations coated with aqueous dispersions of acrylic polymers |
| US5591767A (en) | 1993-01-25 | 1997-01-07 | Pharmetrix Corporation | Liquid reservoir transdermal patch for the administration of ketorolac |
| IT1270594B (it) | 1994-07-07 | 1997-05-07 | Recordati Chem Pharm | Composizione farmaceutica a rilascio controllato di moguisteina in sospensione liquida |
| US6274171B1 (en) | 1996-03-25 | 2001-08-14 | American Home Products Corporation | Extended release formulation of venlafaxine hydrochloride |
| DE10008329A1 (de) | 2000-02-23 | 2001-08-30 | Merck Patent Gmbh | Aminosulfonylbiphenylderivate |
| GB0013378D0 (en) | 2000-06-01 | 2000-07-26 | Glaxo Group Ltd | Use of therapeutic benzamide derivatives |
| JO2390B1 (en) | 2001-04-06 | 2007-06-17 | شركة جانسين فارماسوتيكا ان. في | Diphenylcarboxamides act as lipid-lowering agents |
| TWI319387B (en) | 2002-04-05 | 2010-01-11 | Astrazeneca Ab | Benzamide derivatives |
| NZ545447A (en) * | 2003-07-23 | 2010-03-26 | Synta Pharmaceuticals Corp | Compounds for inflammation and immune-related uses |
| US8084457B2 (en) | 2003-09-15 | 2011-12-27 | Lead Discovery Center Gmbh | Pharmaceutically active 4,6-disubstituted aminopyrimidine derivatives as modulators of protein kinases |
| WO2005073193A1 (en) * | 2004-01-23 | 2005-08-11 | Amgen Inc. | Vanilloid receptor ligands and their use in treatments |
| TW200538433A (en) | 2004-02-24 | 2005-12-01 | Irm Llc | Immunosuppressant compounds and compositiions |
| WO2005117882A2 (en) | 2004-04-20 | 2005-12-15 | Incyte Corporation | Hydroxamic acid derivatives as metalloprotease inhibitors |
| EP1799667B1 (en) | 2004-09-20 | 2013-03-20 | Xenon Pharmaceuticals Inc. | Heterocyclic derivatives and their use as therapeutic agents |
| KR20070057965A (ko) | 2004-09-21 | 2007-06-07 | 신타 파마슈티칼스 코프. | 염증 및 면역 관련 용도를 위한 화합물 |
| MX2007007330A (es) | 2004-12-16 | 2007-10-04 | Vertex Pharma | Piridonas de utilidad como inhibidores de quinasas . |
| WO2006083477A2 (en) | 2005-01-07 | 2006-08-10 | Synta Pharmaceuticals Corp. | Compounds for inflammation and immune-related uses |
| AU2006208045B2 (en) | 2005-01-25 | 2012-08-30 | Synta Pharmaceuticals Corp. | Compounds for inflammation and immune-related uses |
| WO2006081389A1 (en) | 2005-01-25 | 2006-08-03 | Synta Pharmaceuticals Corp. | Thiophene compounds for inflammation and immune-related uses |
| FR2884516B1 (fr) | 2005-04-15 | 2007-06-22 | Cerep Sa | Antagonistes npy, preparation et utilisations |
| CA2639913A1 (en) | 2006-01-25 | 2007-08-02 | Synta Pharmaceutical Corp. | Phenyl and pyridyl compounds for inflammation and immune-related uses |
| CA2640090A1 (en) | 2006-01-25 | 2007-08-02 | Synta Pharmaceuticals Corp. | Substituted aromatic compounds for inflammation and immune-related uses |
| JP2009528273A (ja) | 2006-01-25 | 2009-08-06 | シンタ ファーマシューティカルズ コーポレーション | 炎症および免疫関連使用用の置換ビアリール化合物 |
| JP2009524677A (ja) | 2006-01-25 | 2009-07-02 | シンタ ファーマシューティカルズ コーポレーション | 炎症および免疫関連使用用のチアゾールおよびチアジアゾール化合物 |
| AU2007211276B2 (en) | 2006-01-31 | 2013-06-06 | Synta Pharmaceuticals Corp. | Pyridylphenyl compounds for inflammation and immune-related uses |
| CA2645434A1 (en) | 2006-03-20 | 2007-09-27 | Synta Pharmaceutical Corp. | Benzoimidazolyl-parazine compounds for inflammation and immune-related uses |
| AU2007230911A1 (en) | 2006-03-23 | 2007-10-04 | Synta Pharmaceuticals Corp. | Benzimidazolyl-pyridine compounds for inflammation and immune-related uses |
| US20070254825A1 (en) * | 2006-04-28 | 2007-11-01 | Shannon Thomas G | Enhanced self-warming cleaning products |
| TWI330945B (en) * | 2006-07-06 | 2010-09-21 | Sunplus Technology Co Ltd | Delay control circuit |
| US8779154B2 (en) | 2006-09-26 | 2014-07-15 | Qinglin Che | Fused ring compounds for inflammation and immune-related uses |
| EP2086326B1 (en) | 2006-11-13 | 2014-01-08 | Synta Pharmaceuticals Corp. | Cyclohexenyl-aryl compounds for inflammation and immune-related uses |
| EP2129219A4 (en) | 2007-02-16 | 2012-08-29 | Synta Pharmaceuticals Corp | SUBSTITUTED FUSED CYCLE COMPOUNDS USED IN CASES OF INFLAMMATION OR IMMUNE DISORDERS |
| TW200911800A (en) | 2007-08-01 | 2009-03-16 | Synta Pharmaceuticals Corp | Pyridine compounds for inflammation and immune-related uses |
| ES2440267T3 (es) | 2007-08-01 | 2014-01-28 | Synta Pharmaceuticals Corporation | Compuestos de heterociclo-arilo para la inflamación y usos inmunorrelacionados |
| EP2185514A4 (en) | 2007-08-01 | 2011-05-18 | Synta Pharmaceuticals Corp | VINYL-ARYL DERIVATIVES FOR INFLAMMATORY AND IMMUNE DISORDERS |
| US8324219B2 (en) | 2007-09-20 | 2012-12-04 | Synta Pharmaceuticals Corp. | Substituted benzoimidazolyl-pyrazine compounds for inflammation and immune-related uses |
| US20110052643A1 (en) | 2008-01-07 | 2011-03-03 | Synta Pharmaceuticals Corp. | Compounds for inflammation and immune-related uses |
-
2007
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- 2007-01-25 EP EP07762391.6A patent/EP1984337B1/en active Active
- 2007-01-25 AU AU2007208151A patent/AU2007208151B2/en not_active Ceased
- 2007-01-25 TW TW096102795A patent/TW200806292A/zh unknown
- 2007-01-25 JP JP2008552474A patent/JP2009524683A/ja active Pending
- 2007-01-25 US US11/699,002 patent/US7816535B2/en not_active Expired - Fee Related
- 2007-01-25 CA CA002640091A patent/CA2640091A1/en not_active Abandoned
-
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-
2014
- 2014-05-09 US US14/273,576 patent/US20140248299A1/en not_active Abandoned
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5449687A (en) * | 1992-04-02 | 1995-09-12 | Smithkline Beecham Corporation | 4-phenyl-1,2-cyclohexyl derivatives and anti-inflammatory compositions and methods thereof |
| US6348480B1 (en) * | 1997-10-13 | 2002-02-19 | Yamanouchi Pharmaceutical Co., Ltd. | Pharmaceutical compound comprising a pyrazole derivative and methods of using the same for the treatment of calcium release-activated calcium channel associated diseases |
| US20040014971A1 (en) * | 2000-09-04 | 2004-01-22 | Lieven Meerpoel | Polyarylcarboxamides useful as lipid lowering agents |
Also Published As
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| EP1984337B1 (en) | 2014-04-30 |
| AU2007208151A1 (en) | 2007-08-02 |
| JP2009524683A (ja) | 2009-07-02 |
| TW200806292A (en) | 2008-02-01 |
| US20140248299A1 (en) | 2014-09-04 |
| US7816535B2 (en) | 2010-10-19 |
| EP1984337A2 (en) | 2008-10-29 |
| WO2007087443A2 (en) | 2007-08-02 |
| US20110015184A1 (en) | 2011-01-20 |
| EP1984337A4 (en) | 2010-11-24 |
| US8729069B2 (en) | 2014-05-20 |
| US20070249051A1 (en) | 2007-10-25 |
| WO2007087443A3 (en) | 2007-11-15 |
| CA2640091A1 (en) | 2007-08-02 |
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