AU2006300951A1 - Antibody polypeptide library screening and selected antibody polypeptides - Google Patents

Antibody polypeptide library screening and selected antibody polypeptides Download PDF

Info

Publication number
AU2006300951A1
AU2006300951A1 AU2006300951A AU2006300951A AU2006300951A1 AU 2006300951 A1 AU2006300951 A1 AU 2006300951A1 AU 2006300951 A AU2006300951 A AU 2006300951A AU 2006300951 A AU2006300951 A AU 2006300951A AU 2006300951 A1 AU2006300951 A1 AU 2006300951A1
Authority
AU
Australia
Prior art keywords
antibody
variable domain
chain variable
light chain
heavy chain
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2006300951A
Other languages
English (en)
Inventor
Jasper Clube
Laurent Jespers
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Domantis Ltd
Original Assignee
Domantis Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB0520644A external-priority patent/GB0520644D0/en
Priority claimed from GB0521140A external-priority patent/GB0521140D0/en
Application filed by Domantis Ltd filed Critical Domantis Ltd
Publication of AU2006300951A1 publication Critical patent/AU2006300951A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/005Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies constructed by phage libraries
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/569Single domain, e.g. dAb, sdAb, VHH, VNAR or nanobody®

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Virology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Immunology (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
AU2006300951A 2005-10-11 2006-10-11 Antibody polypeptide library screening and selected antibody polypeptides Abandoned AU2006300951A1 (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
GB0520644.6 2005-10-11
GB0520644A GB0520644D0 (en) 2005-10-11 2005-10-11 Antibody polypeptide library screening and selected antibody polypeptides
GB0521140A GB0521140D0 (en) 2005-10-18 2005-10-18 Antibody polypeptide library screening and selected antibody polypeptides
GB0521140.4 2005-10-18
PCT/GB2006/003781 WO2007042809A2 (en) 2005-10-11 2006-10-11 Antibody polypeptide library screening and selected antibody polypeptides

Publications (1)

Publication Number Publication Date
AU2006300951A1 true AU2006300951A1 (en) 2007-04-19

Family

ID=37943170

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2006300951A Abandoned AU2006300951A1 (en) 2005-10-11 2006-10-11 Antibody polypeptide library screening and selected antibody polypeptides

Country Status (6)

Country Link
US (1) US20100168393A1 (enExample)
EP (1) EP1951754A2 (enExample)
JP (1) JP2009511892A (enExample)
AU (1) AU2006300951A1 (enExample)
CA (1) CA2625222A1 (enExample)
WO (1) WO2007042809A2 (enExample)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7981420B2 (en) 2000-12-22 2011-07-19 Max-Planck-Gesellschaft Zur Foederung Der Wissenschaften E.V. Therapeutic use of antibodies directed against repulsive guidance molecule (RGM)
CN101277974A (zh) 2005-09-30 2008-10-01 阿伯特有限及两合公司 排斥性引导分子(rgm)蛋白质家族的蛋白质的结合结构域及其功能性片段和它们的用途
US8962803B2 (en) 2008-02-29 2015-02-24 AbbVie Deutschland GmbH & Co. KG Antibodies against the RGM A protein and uses thereof
SI2752428T1 (sl) * 2008-06-25 2020-03-31 Novartis Ag Humaniziranje zajčjih protiteles z uporabo univerzalnega ogrodja protitelesa
AU2020201002B2 (en) * 2008-06-25 2022-04-07 Novartis Ag Humanization of rabbit antibodies using a universal antibody framework
AU2009264564B2 (en) 2008-06-25 2014-05-08 Novartis Ag Stable and soluble antibodies inhibiting TNFalpha
SG181563A1 (en) 2009-12-08 2012-07-30 Abbott Gmbh & Co Kg Monoclonal antibodies against the rgm a protein for use in the treatment of retinal nerve fiber layer degeneration
JP5851391B2 (ja) 2010-02-16 2016-02-03 国立大学法人京都工芸繊維大学 抗体固定化担体、抗体固定化担体の製造方法および当該抗体固定化担体の利用
PL2606064T3 (pl) 2010-08-16 2015-07-31 Novimmune Sa Sposoby wytwarzania wieloswoistych i wielowartościowych przeciwciał
AR083495A1 (es) 2010-10-22 2013-02-27 Esbatech Alcon Biomed Res Unit Anticuerpos estables y solubles
WO2012105833A1 (en) 2011-02-01 2012-08-09 Bac Ip B.V. Antigen-binding protein directed against epitope in the ch1 domain of human igg antibodies
ES2676725T3 (es) 2012-01-27 2018-07-24 AbbVie Deutschland GmbH & Co. KG Composición y método para el diagnóstico y el tratamiento de enfermedades asociadas con la degeneración de las neuritas
CN107814845B (zh) * 2016-09-14 2021-02-09 浙江特瑞思药业股份有限公司 新的抗pd-1纳米抗体及其应用
CN107857816B (zh) * 2017-10-17 2020-11-06 北京大学 一种抗干扰素α-2b纳米抗体及其应用
EP3737692A4 (en) 2018-01-09 2021-09-29 Elstar Therapeutics, Inc. CALRETICULIN AND MODIFIED T-LYMPHOCYTES BINDING CONSTRUCTIONS FOR THE TREATMENT OF DISEASES
EP3765517A1 (en) 2018-03-14 2021-01-20 Elstar Therapeutics, Inc. Multifunctional molecules that bind to calreticulin and uses thereof
EP3818083A2 (en) 2018-07-03 2021-05-12 Elstar Therapeutics, Inc. Anti-tcr antibody molecules and uses thereof
AU2020204686A1 (en) * 2019-01-04 2021-07-22 Marengo Therapeutics, Inc. Anti-TCR antibody molecules and uses thereof
CN119661722A (zh) 2019-02-21 2025-03-21 马伦戈治疗公司 结合t细胞相关癌细胞的多功能分子及其用途
SG11202108955QA (en) 2019-02-21 2021-09-29 Marengo Therapeutics Inc Antibody molecules that bind to nkp30 and uses thereof
GB2609554B (en) 2020-01-03 2025-08-20 Marengo Therapeutics Inc Anti-TCR antibody molecules and uses thereof
AU2022298665A1 (en) * 2021-06-22 2024-01-04 University Of Virginia Patent Foundation Compositions and methods for detecting and regulating fibronectin-integrin interactions and signaling
CN114195891B (zh) * 2021-12-22 2023-05-12 北京世纪沃德生物科技有限公司 一种crp驼源单域抗体及其制备方法和应用

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5565332A (en) * 1991-09-23 1996-10-15 Medical Research Council Production of chimeric antibodies - a combinatorial approach
GB9722131D0 (en) * 1997-10-20 1997-12-17 Medical Res Council Method
ZA9811162B (en) * 1997-12-12 2000-06-07 Genentech Inc Treatment with anti-ERBB2 antibodies.
US20060252028A1 (en) * 2002-08-16 2006-11-09 Hiroshi Ueda Method of assaying interaction between proteins
EP1605058B1 (en) * 2003-01-21 2009-05-13 Chugai Seiyaku Kabushiki Kaisha Method of screening light chain of antibody light chains
CA2550155C (en) * 2003-12-15 2015-03-17 Dendreon Corporation Hla-dr-specific antibodies, compositions and methods

Also Published As

Publication number Publication date
US20100168393A1 (en) 2010-07-01
WO2007042809A3 (en) 2007-07-19
JP2009511892A (ja) 2009-03-19
CA2625222A1 (en) 2007-04-19
EP1951754A2 (en) 2008-08-06
WO2007042809A2 (en) 2007-04-19

Similar Documents

Publication Publication Date Title
US20100168393A1 (en) Antibody Polypeptide Libray Screening and Selected Antibody Polypeptides
AU2005291017B2 (en) Single domain antibodies against TNFRl and methods of use therefor
AU2003244817B2 (en) Antigen-binding immunoglobulin single variable domains and dual-specific constructs
AU2008212682B2 (en) Antibody single variable domains against serum albumin
RU2401842C2 (ru) Антагонисты и способы их применения
US20060257406A1 (en) Ligand
JP5901517B2 (ja) 抗原結合性タンパク質
JP2012518398A (ja) 抗原結合性構築物
US20080233130A1 (en) Ligand that has binding specificity for IL-4 and/or IL-13
US9028822B2 (en) Antagonists against TNFR1 and methods of use therefor
US20080008713A1 (en) Single domain antibodies against tnfr1 and methods of use therefor
JP2009504686A (ja) 新世界霊長類領域を用いるキメラ抗体
CN101084014A (zh) 抗肿瘤坏死因子受体1的单域抗体及其使用方法
CN101312988A (zh) 抗体多肽文库筛选和选择的抗体多肽类
JP2012518399A (ja) 抗原結合性構築物
US20110223168A1 (en) Ligand that has binding specificity for il-4 and/or il-13
AU2013273775A1 (en) Antibody single variable domains against serum albumin

Legal Events

Date Code Title Description
MK1 Application lapsed section 142(2)(a) - no request for examination in relevant period