AU2005313108B2 - Heterocycle derivatives as histone deacetylase (HDAC) inhibitors - Google Patents

Heterocycle derivatives as histone deacetylase (HDAC) inhibitors Download PDF

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Publication number
AU2005313108B2
AU2005313108B2 AU2005313108A AU2005313108A AU2005313108B2 AU 2005313108 B2 AU2005313108 B2 AU 2005313108B2 AU 2005313108 A AU2005313108 A AU 2005313108A AU 2005313108 A AU2005313108 A AU 2005313108A AU 2005313108 B2 AU2005313108 B2 AU 2005313108B2
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Australia
Prior art keywords
amino
imidazol
alkyl
ium
methyl
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Expired
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AU2005313108A
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AU2005313108A1 (en
Inventor
Barbara Attenni
Federica Ferrigno
Raffaele Ingenito
Philip Jones
Olaf Kinzel
Laura Llauger Bufi
Jesus Maria Ontoria Ontoria
Giovanna Pescatore
Michael Rowley
Rita Scarpelli
Carsten Schultz
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MSD Italia SRL
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MSD Italia SRL
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Priority claimed from GB0427138A external-priority patent/GB0427138D0/en
Priority claimed from GB0516435A external-priority patent/GB0516435D0/en
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Publication of AU2005313108A1 publication Critical patent/AU2005313108A1/en
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Publication of AU2005313108B2 publication Critical patent/AU2005313108B2/en
Assigned to MSD ITALIA S.R.L. reassignment MSD ITALIA S.R.L. Request for Assignment Assignors: ISTITUTO DI RICERCHE DI BIOLOGIA MOLECOLARE P ANGELETTI SPA
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    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
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    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
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    • C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
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    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links

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  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
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  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
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  • Public Health (AREA)
  • Neurology (AREA)
  • Immunology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Diabetes (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Endocrinology (AREA)
  • Oncology (AREA)
  • Pulmonology (AREA)
  • Dermatology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Hematology (AREA)
  • Communicable Diseases (AREA)
  • Hospice & Palliative Care (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Vascular Medicine (AREA)
  • Rheumatology (AREA)
  • Urology & Nephrology (AREA)
  • Psychiatry (AREA)
  • Psychology (AREA)
  • Emergency Medicine (AREA)
  • Pain & Pain Management (AREA)
  • Ophthalmology & Optometry (AREA)
  • Virology (AREA)
AU2005313108A 2004-12-10 2005-12-09 Heterocycle derivatives as histone deacetylase (HDAC) inhibitors Expired AU2005313108B2 (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
GB0427138.3 2004-12-10
GB0427138A GB0427138D0 (en) 2004-12-10 2004-12-10 Therapeutic compounds
GB0516435.5 2005-08-11
GB0516435A GB0516435D0 (en) 2005-08-11 2005-08-11 Therapeutic compounds
PCT/GB2005/004743 WO2006061638A2 (en) 2004-12-10 2005-12-09 Heterocycle derivatives as histone deacetylase (hdac) inhibitors

Publications (2)

Publication Number Publication Date
AU2005313108A1 AU2005313108A1 (en) 2006-06-15
AU2005313108B2 true AU2005313108B2 (en) 2011-05-26

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Application Number Title Priority Date Filing Date
AU2005313108A Expired AU2005313108B2 (en) 2004-12-10 2005-12-09 Heterocycle derivatives as histone deacetylase (HDAC) inhibitors

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US (1) US7863294B2 (enExample)
EP (1) EP1828171B1 (enExample)
JP (2) JP5197014B2 (enExample)
AU (1) AU2005313108B2 (enExample)
CA (1) CA2590811C (enExample)
ES (1) ES2462341T3 (enExample)
WO (1) WO2006061638A2 (enExample)

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US7863294B2 (en) 2011-01-04
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