AU2004268388A1 - Use of 4,5-dihydro-1H-pyrazole derivatives having CB1-antagonistic activity - Google Patents
Use of 4,5-dihydro-1H-pyrazole derivatives having CB1-antagonistic activity Download PDFInfo
- Publication number
- AU2004268388A1 AU2004268388A1 AU2004268388A AU2004268388A AU2004268388A1 AU 2004268388 A1 AU2004268388 A1 AU 2004268388A1 AU 2004268388 A AU2004268388 A AU 2004268388A AU 2004268388 A AU2004268388 A AU 2004268388A AU 2004268388 A1 AU2004268388 A1 AU 2004268388A1
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- Australia
- Prior art keywords
- treatment
- prophylaxis
- juvenile
- phenyl
- chlorophenyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
- MCGBIXXDQFWVDW-UHFFFAOYSA-N 4,5-dihydro-1h-pyrazole Chemical class C1CC=NN1 MCGBIXXDQFWVDW-UHFFFAOYSA-N 0.000 title description 7
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- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims description 12
- 201000010099 disease Diseases 0.000 claims description 9
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 claims description 9
- -1 trifluoromethoxy, nitro, amino Chemical group 0.000 claims description 9
- 208000020016 psychiatric disease Diseases 0.000 claims description 8
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 claims description 7
- 125000000217 alkyl group Chemical group 0.000 claims description 6
- 150000002431 hydrogen Chemical class 0.000 claims description 6
- 125000003854 p-chlorophenyl group Chemical group [H]C1=C([H])C(*)=C([H])C([H])=C1Cl 0.000 claims description 6
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- 125000004206 2,2,2-trifluoroethyl group Chemical group [H]C([H])(*)C(F)(F)F 0.000 claims description 2
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- 125000000738 acetamido group Chemical group [H]C([H])([H])C(=O)N([H])[*] 0.000 claims description 2
- 125000002777 acetyl group Chemical group [H]C([H])([H])C(*)=O 0.000 claims description 2
- 125000003668 acetyloxy group Chemical group [H]C([H])([H])C(=O)O[*] 0.000 claims description 2
- 125000003545 alkoxy group Chemical group 0.000 claims description 2
- 125000004397 aminosulfonyl group Chemical group NS(=O)(=O)* 0.000 claims description 2
- 125000001797 benzyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])* 0.000 claims description 2
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- QDNFIYLWAMNCGV-UHFFFAOYSA-N 1-[5-(4-chlorophenyl)-4-phenyl-3,4-dihydropyrazol-2-yl]-3-(4-chlorophenyl)sulfonylbutan-1-one Chemical compound C=1C=C(Cl)C=CC=1S(=O)(=O)C(C)CC(=O)N(N=1)CC(C=2C=CC=CC=2)C=1C1=CC=C(Cl)C=C1 QDNFIYLWAMNCGV-UHFFFAOYSA-N 0.000 description 1
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Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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Landscapes
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- Pharmacology & Pharmacy (AREA)
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- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
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- Biomedical Technology (AREA)
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- Child & Adolescent Psychology (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Vascular Medicine (AREA)
- Urology & Nephrology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Obesity (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP03019939 | 2003-09-02 | ||
| EP03019939.2 | 2003-09-02 | ||
| PCT/EP2004/051961 WO2005020988A1 (en) | 2003-09-02 | 2004-08-31 | Use of 4,5-dihydro-1h-pyrazole derivatives having cb1-antagonistic activity |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AU2004268388A1 true AU2004268388A1 (en) | 2005-03-10 |
Family
ID=34259159
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU2004268388A Abandoned AU2004268388A1 (en) | 2003-09-02 | 2004-08-31 | Use of 4,5-dihydro-1H-pyrazole derivatives having CB1-antagonistic activity |
Country Status (11)
| Country | Link |
|---|---|
| EP (1) | EP1663205A1 (de) |
| JP (1) | JP2007504200A (de) |
| CN (2) | CN1845735A (de) |
| AR (1) | AR045533A1 (de) |
| AU (1) | AU2004268388A1 (de) |
| BR (1) | BRPI0413980A (de) |
| CA (1) | CA2537090A1 (de) |
| MX (1) | MXPA06002365A (de) |
| RU (1) | RU2006110543A (de) |
| TW (1) | TW200511990A (de) |
| WO (1) | WO2005020988A1 (de) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2003300967B2 (en) | 2002-12-19 | 2009-05-28 | Merck Sharp & Dohme Corp. | Substituted amides |
| SG163577A1 (en) | 2004-12-03 | 2010-08-30 | Schering Corp | Substituted piperazines as cb1 antagonists |
| WO2009140210A2 (en) * | 2008-05-12 | 2009-11-19 | The Government Of The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services | Radiotracers for imaging cannabinoid sub-type1 (cb1) receptor |
| WO2010079241A1 (es) | 2009-01-12 | 2010-07-15 | Fundacion Hospital Nacional De Paraplejicos Para La Investigacion Y La Integracion | Uso de antagonistas y/o agonistas inversos de los receptores cb1 para la preparación de medicamentos que incrementen la excitabilidad de las motoneuronas |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DZ3335A1 (fr) * | 2000-03-23 | 2001-09-27 | Solvay Pharm Bv | Derives de 4,5-dihydro-1h-pyrazole ayant une activite antagoniste de cb1 |
| ATE284872T1 (de) * | 2001-03-22 | 2005-01-15 | Solvay Pharm Bv | 4,5-dihydro-1h-pyrazolderivate mit cb1- antagonistischer wirkung |
| ATE344663T1 (de) * | 2001-09-21 | 2006-11-15 | Solvay Pharm Bv | Neue 4,5-dihydro-1h-pyrazol-derivate mit cb1- antagonistischer wirkung |
-
2004
- 2004-08-30 TW TW093125980A patent/TW200511990A/zh unknown
- 2004-08-30 AR ARP040103109A patent/AR045533A1/es not_active Application Discontinuation
- 2004-08-31 JP JP2006525143A patent/JP2007504200A/ja active Pending
- 2004-08-31 EP EP04766644A patent/EP1663205A1/de not_active Withdrawn
- 2004-08-31 RU RU2006110543/15A patent/RU2006110543A/ru not_active Application Discontinuation
- 2004-08-31 MX MXPA06002365A patent/MXPA06002365A/es not_active Application Discontinuation
- 2004-08-31 CN CNA2004800248995A patent/CN1845735A/zh active Pending
- 2004-08-31 WO PCT/EP2004/051961 patent/WO2005020988A1/en active Application Filing
- 2004-08-31 AU AU2004268388A patent/AU2004268388A1/en not_active Abandoned
- 2004-08-31 BR BRPI0413980-1A patent/BRPI0413980A/pt not_active IP Right Cessation
- 2004-08-31 CA CA002537090A patent/CA2537090A1/en not_active Abandoned
- 2004-08-31 CN CNA2004800234935A patent/CN1835747A/zh active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| TW200511990A (en) | 2005-04-01 |
| AR045533A1 (es) | 2005-11-02 |
| BRPI0413980A (pt) | 2006-11-07 |
| MXPA06002365A (es) | 2006-06-20 |
| CA2537090A1 (en) | 2005-03-10 |
| RU2006110543A (ru) | 2007-10-10 |
| CN1845735A (zh) | 2006-10-11 |
| CN1835747A (zh) | 2006-09-20 |
| EP1663205A1 (de) | 2006-06-07 |
| WO2005020988A1 (en) | 2005-03-10 |
| JP2007504200A (ja) | 2007-03-01 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| MK4 | Application lapsed section 142(2)(d) - no continuation fee paid for the application |