AU2004242105B2 - Protein kinase C zeta as a drug target for arthritis and other inflammatory diseases - Google Patents
Protein kinase C zeta as a drug target for arthritis and other inflammatory diseases Download PDFInfo
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- AU2004242105B2 AU2004242105B2 AU2004242105A AU2004242105A AU2004242105B2 AU 2004242105 B2 AU2004242105 B2 AU 2004242105B2 AU 2004242105 A AU2004242105 A AU 2004242105A AU 2004242105 A AU2004242105 A AU 2004242105A AU 2004242105 B2 AU2004242105 B2 AU 2004242105B2
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Classifications
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- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/564—Immunoassay; Biospecific binding assay; Materials therefor for pre-existing immune complex or autoimmune disease, i.e. systemic lupus erythematosus, rheumatoid arthritis, multiple sclerosis, rheumatoid factors or complement components C1-C9
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6872—Intracellular protein regulatory factors and their receptors, e.g. including ion channels
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/90—Enzymes; Proenzymes
- G01N2333/91—Transferases (2.)
- G01N2333/912—Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
- G01N2333/91205—Phosphotransferases in general
- G01N2333/9121—Phosphotransferases in general with an alcohol group as acceptor (2.7.1), e.g. general tyrosine, serine or threonine kinases
- G01N2333/91215—Phosphotransferases in general with an alcohol group as acceptor (2.7.1), e.g. general tyrosine, serine or threonine kinases with a definite EC number (2.7.1.-)
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2500/00—Screening for compounds of potential therapeutic value
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/10—Musculoskeletal or connective tissue disorders
- G01N2800/101—Diffuse connective tissue disease, e.g. Sjögren, Wegener's granulomatosis
- G01N2800/102—Arthritis; Rheumatoid arthritis, i.e. inflammation of peripheral joints
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Hematology (AREA)
- Chemical & Material Sciences (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Urology & Nephrology (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
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- Physics & Mathematics (AREA)
- General Physics & Mathematics (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Food Science & Technology (AREA)
- Biochemistry (AREA)
- Pathology (AREA)
- Analytical Chemistry (AREA)
- Rheumatology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Rehabilitation Therapy (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US46898703P | 2003-05-08 | 2003-05-08 | |
| US60/468,987 | 2003-05-08 | ||
| US49127403P | 2003-07-31 | 2003-07-31 | |
| US60/491,274 | 2003-07-31 | ||
| PCT/US2004/014759 WO2004104217A2 (en) | 2003-05-08 | 2004-05-10 | Protein kinase c zeta as a drug target for arthritis and other inflammatory diseases |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| AU2004242105A1 AU2004242105A1 (en) | 2004-12-02 |
| AU2004242105B2 true AU2004242105B2 (en) | 2009-05-28 |
Family
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU2004242105A Expired - Fee Related AU2004242105B2 (en) | 2003-05-08 | 2004-05-10 | Protein kinase C zeta as a drug target for arthritis and other inflammatory diseases |
Country Status (9)
| Country | Link |
|---|---|
| US (2) | US7638482B2 (enExample) |
| EP (1) | EP1629283A2 (enExample) |
| JP (1) | JP2007515940A (enExample) |
| CN (1) | CN1860371B (enExample) |
| AU (1) | AU2004242105B2 (enExample) |
| BR (1) | BRPI0410071A (enExample) |
| CA (1) | CA2525012A1 (enExample) |
| MX (1) | MXPA05011777A (enExample) |
| WO (1) | WO2004104217A2 (enExample) |
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| US20060160062A1 (en) * | 2005-01-14 | 2006-07-20 | Young Lindon H | Perfusion and/or preservation solution for organs |
| WO2006094014A2 (en) | 2005-02-28 | 2006-09-08 | The Regents Of The University Of California | Methods for diagnosis and treatment of endometrial cancer |
| US8318906B2 (en) | 2005-04-15 | 2012-11-27 | The Regents Of The University Of California | EMP2 antibodies and their therapeutic uses |
| US8648052B2 (en) * | 2005-04-15 | 2014-02-11 | The Regents Of The University Of California | Prevention of chlamydia infection using SIRNA |
| WO2006113526A2 (en) | 2005-04-15 | 2006-10-26 | The Regents Of The University Of California | Prevention of chlamydia infection using a protective antibody |
| US9464135B2 (en) | 2007-10-08 | 2016-10-11 | The Regents Of The University Of California | Epithelial membrane protein-2 (EMP2) and proliferative vitroretinopathy (PVR) |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
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| US5565448A (en) * | 1992-02-24 | 1996-10-15 | Smithkline Beecham Corporation | Medicament |
| US6235723B1 (en) * | 1992-03-16 | 2001-05-22 | Isis Pharmaceuticals , Inc. | Antisense oligonucleotide modulation of human protein kinase C-δ expression |
| US5681747A (en) * | 1992-03-16 | 1997-10-28 | Isis Pharmaceuticals, Inc. | Nucleic acid sequences encoding protein kinase C and antisense inhibition of expression thereof |
| US6506559B1 (en) | 1997-12-23 | 2003-01-14 | Carnegie Institute Of Washington | Genetic inhibition by double-stranded RNA |
| US6368831B1 (en) * | 1998-06-29 | 2002-04-09 | Childrens Hospital Los Angeles | Treatment of hyperproliferative disorders |
| JP2002532503A (ja) * | 1998-12-17 | 2002-10-02 | エフ．ホフマン−ラ ロシュ アーゲー | プロテインキナーゼ阻害剤としての４，５−ピラジノオキシンドール |
| JP2003503360A (ja) * | 1999-06-24 | 2003-01-28 | ファルマシア コーポレイション | 炎症性疾患の処置のための併用療法 |
| ES2213996T3 (es) * | 1999-12-08 | 2004-09-01 | Centre National De La Recherche Scientifique (Cnrs) | Uso de himenialdisina o sus derivados en la fabricacion de medicamentos. |
| DE60109018T2 (de) * | 2000-12-18 | 2005-07-21 | Meiji Dairies Corp. | Kavalactone als Hemmer der TNF-alpha Produktion |
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2004
- 2004-05-10 AU AU2004242105A patent/AU2004242105B2/en not_active Expired - Fee Related
- 2004-05-10 US US10/842,142 patent/US7638482B2/en not_active Expired - Fee Related
- 2004-05-10 WO PCT/US2004/014759 patent/WO2004104217A2/en not_active Ceased
- 2004-05-10 BR BRPI0410071-9A patent/BRPI0410071A/pt not_active IP Right Cessation
- 2004-05-10 CN CN2004800124155A patent/CN1860371B/zh not_active Expired - Fee Related
- 2004-05-10 CA CA002525012A patent/CA2525012A1/en not_active Abandoned
- 2004-05-10 EP EP04751923A patent/EP1629283A2/en not_active Withdrawn
- 2004-05-10 JP JP2006532963A patent/JP2007515940A/ja active Pending
- 2004-05-10 MX MXPA05011777A patent/MXPA05011777A/es not_active Application Discontinuation
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2009
- 2009-11-11 US US12/616,484 patent/US20100062448A1/en not_active Abandoned
Non-Patent Citations (1)
| Title |
|---|
| Journal of Biological Chemistry, 277(30): 27345-52 * |
Also Published As
| Publication number | Publication date |
|---|---|
| CA2525012A1 (en) | 2004-12-02 |
| EP1629283A2 (en) | 2006-03-01 |
| CN1860371B (zh) | 2010-11-24 |
| US20040259136A1 (en) | 2004-12-23 |
| US7638482B2 (en) | 2009-12-29 |
| CN1860371A (zh) | 2006-11-08 |
| WO2004104217A3 (en) | 2005-11-24 |
| JP2007515940A (ja) | 2007-06-21 |
| BRPI0410071A (pt) | 2006-05-23 |
| AU2004242105A1 (en) | 2004-12-02 |
| MXPA05011777A (es) | 2006-01-26 |
| WO2004104217A2 (en) | 2004-12-02 |
| US20100062448A1 (en) | 2010-03-11 |
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| MK25 | Application lapsed reg. 22.2i(2) - failure to pay acceptance fee |