AU2004215658B2 - Novel diazabicyclic aryl derivatives - Google Patents

Novel diazabicyclic aryl derivatives Download PDF

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Publication number
AU2004215658B2
AU2004215658B2 AU2004215658A AU2004215658A AU2004215658B2 AU 2004215658 B2 AU2004215658 B2 AU 2004215658B2 AU 2004215658 A AU2004215658 A AU 2004215658A AU 2004215658 A AU2004215658 A AU 2004215658A AU 2004215658 B2 AU2004215658 B2 AU 2004215658B2
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Australia
Prior art keywords
phenyl
diaza
bicyclo
furan
methanone
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Ceased
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AU2004215658A
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AU2004215658A1 (en
Inventor
Philip K. Ahring
Tino Dyhring Jorgensen
Elsebet Ostergaard Nielsen
Gunnar M. Olsen
Dan Peters
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NTG Nordic Transport Group AS
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Neurosearch AS
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/08—Bridged systems
    • A—HUMAN NECESSITIES
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  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Psychiatry (AREA)
  • Addiction (AREA)
  • Endocrinology (AREA)
  • Pain & Pain Management (AREA)
  • Reproductive Health (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Diabetes (AREA)
  • Gynecology & Obstetrics (AREA)
  • Pulmonology (AREA)
  • Psychology (AREA)
  • Pregnancy & Childbirth (AREA)
  • Hospice & Palliative Care (AREA)
  • Child & Adolescent Psychology (AREA)
  • Anesthesiology (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Dermatology (AREA)
  • Nutrition Science (AREA)
  • Urology & Nephrology (AREA)
AU2004215658A 2003-02-27 2004-02-04 Novel diazabicyclic aryl derivatives Ceased AU2004215658B2 (en)

Applications Claiming Priority (9)

Application Number Priority Date Filing Date Title
US44987103P 2003-02-27 2003-02-27
DKPA200300310 2003-02-27
US60/449,871 2003-02-27
DKPA200300310 2003-02-27
DKPA200300940 2003-06-24
DKPA200300940 2003-06-24
US48202203P 2003-06-25 2003-06-25
US60/482,022 2003-06-25
PCT/EP2004/050079 WO2004076453A1 (en) 2003-02-27 2004-02-04 Novel diazabicyclic aryl derivatives

Publications (2)

Publication Number Publication Date
AU2004215658A1 AU2004215658A1 (en) 2004-09-10
AU2004215658B2 true AU2004215658B2 (en) 2010-06-24

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ID=32931427

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Application Number Title Priority Date Filing Date
AU2004215658A Ceased AU2004215658B2 (en) 2003-02-27 2004-02-04 Novel diazabicyclic aryl derivatives

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US (2) US7678788B2 (enExample)
EP (1) EP1599476B1 (enExample)
JP (1) JP2006519208A (enExample)
AT (1) ATE445618T1 (enExample)
AU (1) AU2004215658B2 (enExample)
BR (1) BRPI0407216A (enExample)
CA (1) CA2518675A1 (enExample)
DE (1) DE602004023586D1 (enExample)
MX (1) MXPA05006861A (enExample)
NZ (1) NZ540998A (enExample)
WO (1) WO2004076453A1 (enExample)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE0202430D0 (sv) * 2002-08-14 2002-08-14 Astrazeneca Ab New Compounds
SE0202465D0 (sv) * 2002-08-14 2002-08-14 Astrazeneca Ab New compounds
US7094572B2 (en) 2003-03-14 2006-08-22 Bristol-Myers Squibb Polynucleotide encoding a novel human G-protein coupled receptor variant of HM74, HGPRBMY74
TW200529860A (en) * 2003-12-22 2005-09-16 Astrazeneca Ab Nicotinic acetylcholine receptor ligands
US20080227772A1 (en) * 2004-02-04 2008-09-18 Neurosearch A/S Diazabicyclic Aryl Derivatives as Nicotinic Acetylcholine Receptor Ligands
EP1713809B1 (en) * 2004-02-04 2009-07-29 Neurosearch A/S Dimeric azacyclic compounds and their use
KR20070015607A (ko) 2004-05-07 2007-02-05 메모리 파마슈티칼스 코포레이션 1ｈ-인다졸, 벤조티아졸, 1,2-벤조이속사졸,1,2-벤조이소티아졸, 및 크로몬 및 그의 제조법 및 용도
EP1751150A2 (en) 2004-05-19 2007-02-14 Neurosearch A/S Novel azabicyclic aryl derivatives
TWI405763B (zh) 2006-11-02 2013-08-21 Targacept Inc 菸鹼乙醯膽鹼受體亞型選擇性之二氮雜雙環烷類醯胺
SA08290475B1 (ar) 2007-08-02 2013-06-22 Targacept Inc (2s، 3r)-n-(2-((3-بيردينيل)ميثيل)-1-آزا بيسيكلو[2، 2، 2]أوكت-3-يل)بنزو فيوران-2-كربوكساميد، وصور أملاحه الجديدة وطرق استخدامه
GB0723814D0 (en) * 2007-12-05 2008-01-16 Glaxo Group Ltd Compounds
DE102008015032A1 (de) 2008-03-17 2009-09-24 Aicuris Gmbh & Co. Kg Substituierte Pyrazolamide und ihre Verwendung
DE102008015033A1 (de) 2008-03-17 2009-09-24 Aicuris Gmbh & Co. Kg Substituierte (Pyrazolyl-carbonyl)imidazolidinone und ihre Verwendung
DE102008062878A1 (de) 2008-12-17 2010-06-24 Aicuris Gmbh & Co. Kg Substituierte Furancarboxamide und ihre Verwendung
DE102008062863A1 (de) 2008-12-17 2010-06-24 Aicuris Gmbh & Co. Kg Substituierte (Thiophenyl-carbonyl)imidazolidinone und ihre Verwendung
TW201031664A (en) 2009-01-26 2010-09-01 Targacept Inc Preparation and therapeutic applications of (2S,3R)-N-2-((3-pyridinyl)methyl)-1-azabicyclo[2.2.2]oct-3-yl)-3,5-difluorobenzamide
TWI558398B (zh) 2009-09-22 2016-11-21 諾華公司 菸鹼乙醯膽鹼受體α７活化劑之用途
CA2822357A1 (en) 2010-12-22 2012-06-28 Abbvie Inc. Hepatitis c inhibitors and uses thereof

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2003248592A1 (en) * 2002-08-14 2004-03-03 Astrazeneca Ab Biaryl diazabicycloalkane amides as nicotinic acetylcholine agonists

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US7122339B2 (en) * 1998-10-09 2006-10-17 Medical Research Council Method for generating diversity
FR2791678B1 (fr) 1999-03-30 2001-05-04 Synthelabo Derives de 1,4-diazabicyclo [3.2.2] nonane-4-carboxylates et -carboxamides, leur preparation et leur application en therapeutique
DE60008866T2 (de) * 1999-05-04 2005-01-27 Neurosearch A/S Heteroaryl diazabicycloalkene, deren herstellung und verwendung
FR2804430B1 (fr) * 2000-01-28 2002-03-22 Sanofi Synthelabo Derives de 4-heteroaryl-1,4-diazabicyclo[3.2.2] nonane, leur preparation et leur application en therapeutique
FR2809731B1 (fr) * 2000-05-31 2002-07-19 Sanofi Synthelabo Derives de 1,4-diazabicyclo-[3.2.2] nonane-pheylisoxazole, leur preparation et leur application en therapeutique
FR2809730B1 (fr) * 2000-05-31 2002-07-19 Sanofi Synthelabo Derives de 1,4-diazabicyclo[3.2.2] nonanebenzoxazole, -benzothiazole et -benzimidazole, leur preparation et leur application therapeutique
US20020086871A1 (en) * 2000-12-29 2002-07-04 O'neill Brian Thomas Pharmaceutical composition for the treatment of CNS and other disorders
DE60216830T2 (de) 2001-02-06 2007-06-14 Pfizer Products Inc., Groton Pharmazeutische Zusammensetzungen zur Behandlung von Störungen des ZNS oder anderen Erkrankungen
FR2832713B1 (fr) 2001-11-23 2004-02-13 Sanofi Synthelabo Derives de 4-(1,3,4-thiadiazol-2-yl)-1,4-diazabicyclo[3.2.2] nonane, leur preparation et leur application en therapeutique
FR2832712B1 (fr) 2001-11-23 2004-02-13 Sanofi Synthelabo Derives de 4-(oxadiazol-3-yl)-1,4-diazabicyclo[3.2.2]nonane, leur preparation et leur application en therapeutique
US20050227699A1 (en) 2002-06-26 2005-10-13 Harmen Schreuder Method and network element for optimisation of radio resource utilisation in radio access network
SE0202465D0 (sv) * 2002-08-14 2002-08-14 Astrazeneca Ab New compounds
DE60326894D1 (de) 2002-09-30 2009-05-07 Neurosearch As 1,4-Diazabicycloalkanderivate, deren Herstellung und Verwendung

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2003248592A1 (en) * 2002-08-14 2004-03-03 Astrazeneca Ab Biaryl diazabicycloalkane amides as nicotinic acetylcholine agonists

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CA2518675A1 (en) 2004-09-10
US7678788B2 (en) 2010-03-16
MXPA05006861A (es) 2005-12-12
DE602004023586D1 (de) 2009-11-26
NZ540998A (en) 2008-06-30
EP1599476A1 (en) 2005-11-30
BRPI0407216A (pt) 2006-01-24
WO2004076453A1 (en) 2004-09-10
AU2004215658A1 (en) 2004-09-10
ATE445618T1 (de) 2009-10-15
EP1599476B1 (en) 2009-10-14
JP2006519208A (ja) 2006-08-24
US20060148789A1 (en) 2006-07-06
US20100130483A1 (en) 2010-05-27

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