AU2003286069A1 - Chimeric alpha q-gustducin g-proteins - Google Patents

Chimeric alpha q-gustducin g-proteins

Info

Publication number
AU2003286069A1
AU2003286069A1 AU2003286069A AU2003286069A AU2003286069A1 AU 2003286069 A1 AU2003286069 A1 AU 2003286069A1 AU 2003286069 A AU2003286069 A AU 2003286069A AU 2003286069 A AU2003286069 A AU 2003286069A AU 2003286069 A1 AU2003286069 A1 AU 2003286069A1
Authority
AU
Australia
Prior art keywords
gustducin
proteins
chimeric
chimeric alpha
taste
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2003286069A
Other languages
English (en)
Other versions
AU2003286069A8 (en
Inventor
Thomas Scott Mccluskey
Jay Patrick Slack
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Givaudan SA
Original Assignee
Givaudan SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Givaudan SA filed Critical Givaudan SA
Publication of AU2003286069A1 publication Critical patent/AU2003286069A1/en
Publication of AU2003286069A8 publication Critical patent/AU2003286069A8/xx
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4722—G-proteins

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Toxicology (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
AU2003286069A 2002-12-18 2003-12-17 Chimeric alpha q-gustducin g-proteins Abandoned AU2003286069A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US43479002P 2002-12-18 2002-12-18
US60/434,790 2002-12-18
PCT/CH2003/000830 WO2004055048A2 (en) 2002-12-18 2003-12-17 Chimeric alpha q-gustducin g-proteins

Publications (2)

Publication Number Publication Date
AU2003286069A1 true AU2003286069A1 (en) 2004-07-09
AU2003286069A8 AU2003286069A8 (en) 2004-07-09

Family

ID=32595305

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2003286069A Abandoned AU2003286069A1 (en) 2002-12-18 2003-12-17 Chimeric alpha q-gustducin g-proteins

Country Status (10)

Country Link
US (2) US7919236B2 (https=)
EP (1) EP1581555B1 (https=)
JP (2) JP4654038B2 (https=)
CN (1) CN1726224A (https=)
AT (1) ATE393778T1 (https=)
AU (1) AU2003286069A1 (https=)
CA (1) CA2507387A1 (https=)
DE (1) DE60320682T2 (https=)
ES (1) ES2305536T3 (https=)
WO (1) WO2004055048A2 (https=)

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US7368285B2 (en) 2001-03-07 2008-05-06 Senomyx, Inc. Heteromeric umami T1R1/T1R3 taste receptors and isolated cells that express same
DK2327985T3 (en) 2001-06-26 2016-09-05 Senomyx Inc H1 Oligomeric T1R Taste Receptors and Cell Lines Expressing the Receptors, and Their Use to Identify Taste Compounds
AU2003286069A1 (en) * 2002-12-18 2004-07-09 Givaudan Sa Chimeric alpha q-gustducin g-proteins
WO2006046854A2 (en) 2004-10-29 2006-05-04 Quest International B.V. Flavour modulating substances
BRPI0518075B8 (pt) 2004-10-29 2017-05-16 Quest Int Services B V composição flavorizante, produto, e, processo de melhorar o flavor de um alimento, de uma bebida ou de um produto farmacêutico
DE602005015849D1 (de) 2005-09-02 2009-09-17 Givaudan Nederland Services B Geschmackverstärker
WO2007121604A2 (en) 2006-04-20 2007-11-01 Givaudan Sa Method relating to sweetness enhancement
US20110097741A1 (en) * 2006-04-20 2011-04-28 Jay Patrick Slack Partial t1r2 nucleic acid sequence, receptor protein and its use in screening assays
JP2009533065A (ja) * 2006-04-20 2009-09-17 ジボダン エス エー 味覚物質同定のための機能的方法
ATE444280T1 (de) 2006-05-05 2009-10-15 Givaudan Nederland Services B Zusammensetzung zur verbesserung von geschmack
US8039233B2 (en) * 2007-01-18 2011-10-18 Givaudan S.A. Nucleic acid sequences and their use in methods to identify umami modulatiors
EP1975611A1 (en) 2007-03-29 2008-10-01 Deutsches Institut für Ernährungsforschung Potsdam -Rehbrücke-Stiftung des öffentlichen Rechts- Vertreten durch den Stiftungsvorstand Agonists of bitter taste receptors and uses thereof
EP2137322B1 (en) * 2007-03-30 2013-02-27 Givaudan SA Methods to identify tas2r modulators
KR20100131969A (ko) * 2007-12-10 2010-12-16 메타프로테오믹스, 엘엘씨 암, 혈관신생 및 이와 관련된 염증 경로의 치환된 1,3-시클로펜타디온 다중-표적 단백질 키나아제 조절제
EP2108954A1 (en) 2008-04-10 2009-10-14 Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. A test system for detecting intracellular cyclic nucleotide level and methods and uses thereof
US8546085B2 (en) * 2008-06-13 2013-10-01 Givaudan Sa Methods of identifying modulators of the bitter taste receptor TAS2R44
JP5576653B2 (ja) * 2008-12-26 2014-08-20 サントリー食品インターナショナル株式会社 環状ジペプチド含有飲料
EP2924112A1 (en) * 2009-02-02 2015-09-30 Chromocell Corporation Novel cell lines and methods
US20130123135A1 (en) 2010-05-07 2013-05-16 Jay Patrick Slack Methods To Identify Modulators of TAS2R48 Receptors
US20130115624A1 (en) 2010-05-07 2013-05-09 Givaudan S.A. Methods To Identify Modulators
JP5906013B2 (ja) * 2010-12-10 2016-04-20 花王株式会社 苦味抑制剤の評価・選択方法
EP2661266B1 (en) 2011-01-07 2020-09-16 Anji Pharma (US) LLC Chemosensory receptor ligand-based therapies
US9795792B2 (en) 2011-02-25 2017-10-24 Medtronic, Inc. Emergency mode switching for non-pacing modes
US9128079B2 (en) 2011-08-08 2015-09-08 The Coca-Cola Company Methods of using lung or bronchial epithelial cells to identify bitter taste modulators
WO2013072332A1 (en) 2011-11-14 2013-05-23 Givaudan Sa Methods of using antagonists of bitter taste receptors
KR20190120430A (ko) 2012-01-06 2019-10-23 엘셀릭스 테라퓨틱스 인코포레이티드 바이구아나이드 조성물 및 대사 장애를 치료하는 방법
EP2800562A2 (en) 2012-01-06 2014-11-12 Elcelyx Therapeutics, Inc. Compositions and methods for treating metabolic disorders
HK1210825A1 (en) 2012-07-11 2016-05-06 Elcelyx Therapeutics, Inc. Compositions comprising statins, biguanides and further agents for reducing cardiometabolic risk
CN105101956B (zh) 2013-01-05 2018-12-07 埃尔舍利克斯治疗公司 包含双胍的延迟释放组合物
EP2983507B1 (en) 2013-03-15 2020-04-22 Applied Food Biotechnology, Inc. Feline bitter taste receptors and methods
US9804157B1 (en) 2013-03-15 2017-10-31 Senomyx, Inc. Screening assays to identify compounds which modulate T1R associated taste modalities which eliminate false positives
JP6367315B2 (ja) * 2013-05-10 2018-08-01 ペプシコ, インコーポレイテッドPepsiCo Inc. 潜在的味覚調節物質を特定するためのモデルとしての細胞
WO2014183041A1 (en) 2013-05-10 2014-11-13 Pepsico, Inc. Taste receptor internalization assay
JP6755640B2 (ja) 2014-03-28 2020-09-16 味の素株式会社 甘味受容体キメラタンパク質及びその利用
WO2017066799A1 (en) * 2015-10-16 2017-04-20 Cornell University Sweeteners having enhanced organoleptic properties
JP6924590B2 (ja) * 2016-03-14 2021-08-25 サントリーホールディングス株式会社 苦味評価のための融合タンパク質および苦味評価方法
CN108611324A (zh) * 2018-05-07 2018-10-02 云南中烟工业有限责任公司 一种稳定共表达重组人源甜味受体蛋白的真核细胞系及其制备方法
WO2025183058A1 (ja) * 2024-02-29 2025-09-04 味の素株式会社 植物由来タンパク質含有食品における異味・異風味をマスキングする物質のスクリーニング方法および異味・異風味のマスキング用の組成物
CN119193656A (zh) * 2024-09-24 2024-12-27 上海交通大学 一种响应鲜味信号的酵母细胞模型及其制备方法与应用

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5817759A (en) * 1992-04-09 1998-10-06 Linguagen Corporation Gustducin polypeptides and fragments
EP1214343A2 (en) 1999-09-10 2002-06-19 The Regents Of The University Of California T2r taste receptor family
US6462178B1 (en) * 1999-11-17 2002-10-08 Yong Hou Wong G protein
WO2002036622A2 (en) 2000-10-30 2002-05-10 Senomyx, Inc. GαqPROETIN VARIANTS AND THEIR USE IN THE ANALYSIS AND DISCOVERY OF AGONISTS AND ANTAGONISTS OF CHEMOSENSORY RECEPTORS
US7041457B2 (en) * 2000-10-30 2006-05-09 Senomyx, Inc. Gαq protein variants and their use in the analysis and discovery of agonists and antagonists of chemosensory receptors
AU2003286069A1 (en) * 2002-12-18 2004-07-09 Givaudan Sa Chimeric alpha q-gustducin g-proteins

Also Published As

Publication number Publication date
EP1581555B1 (en) 2008-04-30
ES2305536T3 (es) 2008-11-01
US8609362B2 (en) 2013-12-17
DE60320682T2 (de) 2009-06-10
CA2507387A1 (en) 2004-07-01
JP5425651B2 (ja) 2014-02-26
US20110177545A1 (en) 2011-07-21
WO2004055048A3 (en) 2004-09-16
WO2004055048A2 (en) 2004-07-01
JP4654038B2 (ja) 2011-03-16
JP2006524483A (ja) 2006-11-02
EP1581555A2 (en) 2005-10-05
JP2010187666A (ja) 2010-09-02
DE60320682D1 (de) 2008-06-12
AU2003286069A8 (en) 2004-07-09
ATE393778T1 (de) 2008-05-15
US7919236B2 (en) 2011-04-05
CN1726224A (zh) 2006-01-25
US20060275765A1 (en) 2006-12-07

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Legal Events

Date Code Title Description
MK6 Application lapsed section 142(2)(f)/reg. 8.3(3) - pct applic. not entering national phase