AU2003234186B2 - Peptide inhibitors of protein kinase C Gamma for pain management - Google Patents
Peptide inhibitors of protein kinase C Gamma for pain management Download PDFInfo
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- AU2003234186B2 AU2003234186B2 AU2003234186A AU2003234186A AU2003234186B2 AU 2003234186 B2 AU2003234186 B2 AU 2003234186B2 AU 2003234186 A AU2003234186 A AU 2003234186A AU 2003234186 A AU2003234186 A AU 2003234186A AU 2003234186 B2 AU2003234186 B2 AU 2003234186B2
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids
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- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
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- Animal Behavior & Ethology (AREA)
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- Pain & Pain Management (AREA)
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- Epidemiology (AREA)
- Gastroenterology & Hepatology (AREA)
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- Orthopedic Medicine & Surgery (AREA)
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Priority Applications (1)
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| AU2009201593A AU2009201593B2 (en) | 2002-04-22 | 2009-04-22 | Peptide inhibitors of protein kinase C y for pain management |
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| US37453002P | 2002-04-22 | 2002-04-22 | |
| US60/374,530 | 2002-04-22 | ||
| PCT/US2003/012542 WO2003089457A2 (en) | 2002-04-22 | 2003-04-22 | Peptide inhibitors of protein kinase c ϝ for pain management |
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| AU2009201593A Division AU2009201593B2 (en) | 2002-04-22 | 2009-04-22 | Peptide inhibitors of protein kinase C y for pain management |
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| AU2003234186A1 AU2003234186A1 (en) | 2003-11-03 |
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| AU2009201593A Ceased AU2009201593B2 (en) | 2002-04-22 | 2009-04-22 | Peptide inhibitors of protein kinase C y for pain management |
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| AU2009201760A Ceased AU2009201760B2 (en) | 2002-04-22 | 2009-05-04 | Peptide inhibitors of protein kinase C |
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| EP (3) | EP2332559A1 (OSRAM) |
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| AU (4) | AU2003234186B2 (OSRAM) |
| CA (3) | CA2785889A1 (OSRAM) |
| WO (2) | WO2003089457A2 (OSRAM) |
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| US7507711B2 (en) | 2002-04-22 | 2009-03-24 | The Board Of Trustees Of The Leland Stanford Junior University | Peptide inhibitors of protein kinase C |
| US6933275B2 (en) * | 2002-05-01 | 2005-08-23 | The Board Of Trustees Of The Leland Stanford Junior University | Protein kinase C peptides for use in withdrawal |
| WO2004084889A1 (en) * | 2003-03-28 | 2004-10-07 | Pfizer Inc. | Use of protein kinase c inhibitor for suppressing sustained slow postsynaptic excitation (sspe) of enteric neurons |
| AU2003241559A1 (en) * | 2003-05-16 | 2004-12-13 | The Board Of Trustees Of The Leland Stanford Junior University | Protein kinase c peptides for use in withdrawal |
| AU2003264918A1 (en) * | 2003-10-02 | 2005-04-21 | The Board Of Trustees Of The Leland Stanford Junior University | Protein kinase c peptides for use in withdrawal |
| US8133733B2 (en) * | 2003-10-24 | 2012-03-13 | Gencia Corporation | Nonviral vectors for delivering polynucleotides to target tissues |
| US20090208478A1 (en) * | 2003-10-24 | 2009-08-20 | Gencia Corporation | Transducible polypeptides for modifying metabolism |
| US8507277B2 (en) * | 2003-10-24 | 2013-08-13 | Gencia Corporation | Nonviral vectors for delivering polynucleotides |
| JP4838722B2 (ja) | 2003-10-24 | 2011-12-14 | ゲンシア コーポレーション | ポリヌクレオチドを送達する方法、及び送達用組成物 |
| US20090123468A1 (en) * | 2003-10-24 | 2009-05-14 | Gencia Corporation | Transducible polypeptides for modifying metabolism |
| US8062891B2 (en) | 2003-10-24 | 2011-11-22 | Gencia Corporation | Nonviral vectors for delivering polynucleotides to plants |
| CA2549052A1 (en) * | 2003-12-11 | 2005-06-30 | The Board Of Trustees Of The Leland Stanford Junior University | Isozyme-specific antagonists of protein kinase c |
| US7265092B2 (en) * | 2004-09-30 | 2007-09-04 | Kai Pharmaceuticals, Inc. | Pharmaceutical formulation |
| US20060148700A1 (en) * | 2004-11-10 | 2006-07-06 | Daria Mochly-Rosen | Methods and compositions for reducing injury to a transplanted organ |
| US20060160062A1 (en) * | 2005-01-14 | 2006-07-20 | Young Lindon H | Perfusion and/or preservation solution for organs |
| US8158586B2 (en) * | 2005-04-11 | 2012-04-17 | Pharmagap Inc. | Inhibitors of protein kinases and uses thereof |
| WO2007016763A1 (en) * | 2005-08-05 | 2007-02-15 | Pharmagap Inc. | Peptides targeted to protein kinase c isoforms and uses thereof |
| US20070054843A1 (en) | 2005-08-26 | 2007-03-08 | Yeomans David C | Methods for treatment of headaches by administration of oxytocin |
| EP2194124A1 (en) * | 2005-09-19 | 2010-06-09 | Kai Pharmaceuticals, Inc. | Protein kinase c peptide modulators of angiogenesis |
| WO2007112556A1 (en) * | 2006-03-30 | 2007-10-11 | Salpep Biotechnology Inc. | Suppression and treatment of neuropathic pain |
| US7741290B2 (en) * | 2006-06-01 | 2010-06-22 | The Board of Trustee of The Leland Stanford Juinior University | Method of preventing progression of hypertension-induced heart failure with PKC peptides |
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| US20090062208A1 (en) * | 2007-02-06 | 2009-03-05 | Mochly-Rosen Daria D | Methods for maintaining blood-brain barrier integrity in hypertensive subjects using a delta-PKC inhibitor |
| US20090062178A1 (en) * | 2007-04-06 | 2009-03-05 | Harrison Stephen D | Methods of use of gamma inhibitor compounds for the attenuation of pain |
| US20090137493A1 (en) * | 2007-06-07 | 2009-05-28 | Mochly-Rosen Daria D | Inhibition of tumor metastases using protein kinase C (PKC) inhibitors |
| US8975237B2 (en) | 2007-12-21 | 2015-03-10 | Coda Therapeutics, Inc. | Treatment of fibrotic conditions |
| US20090318351A1 (en) * | 2008-03-12 | 2009-12-24 | Kevin Grimes | Method of treating acute st-elevation myocardial infarction with a delta pkc antagonist |
| CA2719059C (en) * | 2008-03-27 | 2016-05-17 | Nestec S.A. | Methods for increasing absorption of peptides, peptidomimetics, and other gastrointestinal transport protein substrates |
| WO2010019965A1 (en) * | 2008-08-15 | 2010-02-18 | The Board Of Trustees Of The Leland Stanford Junior University | Compositions and methods for modulating epsilon protein kinase c-mediated cytoprotection |
| US8557580B2 (en) | 2009-02-20 | 2013-10-15 | Cellular Dynamics International, Inc. | Methods and compositions for the differentiation of stem cells |
| KR101720961B1 (ko) * | 2009-02-27 | 2017-03-29 | 셀룰러 다이내믹스 인터내셔널, 인코포레이티드 | 다능성 세포의 분화 |
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| US8697629B2 (en) * | 2010-03-05 | 2014-04-15 | Angstrom Pharmaceuticals, Inc. | Modulation of intracellular signaling |
| US8785648B1 (en) | 2010-08-10 | 2014-07-22 | The Regents Of The University Of California | PKC-epsilon inhibitors |
| US9217137B2 (en) | 2011-08-12 | 2015-12-22 | The Board Of Trustees Of The Leland Stanford Junior University | Compositions and methods for specific regulation of pyruvate dehydrogenase kinase |
| AU2013251785B2 (en) | 2012-04-24 | 2018-05-10 | Dan S. Kaufman | Method for developing natural killer cells from stem cells |
| JP6998657B2 (ja) | 2013-09-18 | 2022-02-04 | エピアクシス セラピューティクス プロプライエタリー リミテッド | 幹細胞調節ｉｉ |
| WO2016003450A1 (en) | 2014-07-01 | 2016-01-07 | The Regents Of The University Of California | Pkc-epsilon inhibitors |
| WO2016029262A1 (en) | 2014-08-25 | 2016-03-03 | University Of Canberra | Compositions for modulating cancer stem cells and uses therefor |
| HRP20231438T1 (hr) | 2015-01-07 | 2024-06-07 | Tonix Pharma Limited | Formulacije oksitocina koje sadrže magnezij i načini uporabe |
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| CA3087881A1 (en) | 2017-01-17 | 2018-07-26 | Michael David FORREST | Therapeutic inhibitors of the reverse mode of atp synthase |
| BR112019028172A2 (pt) | 2017-07-13 | 2020-10-06 | Michael David Forrest | moduladores terapêuticos do modo reverso da atp sintase |
| US20200282010A1 (en) | 2017-11-08 | 2020-09-10 | Epiaxis Therapeutics Pty Ltd | Immunogenic compositions and uses therefor |
| EP4078221A1 (en) * | 2019-12-16 | 2022-10-26 | Sony Semiconductor Solutions Corporation | Time-of-flight imaging circuitry, time-of-flight imaging system, time-of-flight imaging method |
| TW202146071A (zh) * | 2020-03-31 | 2021-12-16 | 日商東麗股份有限公司 | 影像解析裝置、影像解析裝置的控制方法、影像解析系統、及影像解析系統的控制方法 |
| KR20230135586A (ko) | 2021-01-24 | 2023-09-25 | 마이클 데이비드 포레스트 | Atp 합성효소 억제제 - 미용 및 치료 용도 |
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| US4351829A (en) | 1980-09-26 | 1982-09-28 | Farmitalia Carlo Erba Spa | Use of polypeptides as analgesic drugs |
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| US6376467B1 (en) * | 1998-10-09 | 2002-04-23 | The Regents Of The University Of California | Use of inhibitors of protein kinase C epsilon to treat pain |
| DE69934689T2 (de) | 1998-07-06 | 2007-10-25 | The Regents Of The University Of California, Oakland | Verwendung der protein-kinase-c-epsilon-inhibitoren zur behandlung von schmerzen |
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| GB2341389B (en) | 1998-09-14 | 2000-07-12 | Pan Pacific Pharmaceuticals In | Useful properties of a bee venom protein and gene encoding same |
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| GB9905218D0 (en) * | 1999-03-09 | 1999-04-28 | Univ Glasgow | Neurodegenerative disorder related gene |
| WO2001044497A2 (en) * | 1999-12-02 | 2001-06-21 | University Of Dundee | Protein kinase regulation |
| CN1300845A (zh) | 1999-12-22 | 2001-06-27 | 上海博德基因开发有限公司 | 一种新的多肽－人二酰基甘油蛋白激酶亚单位9和编码这种多肽的多核苷酸 |
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| AU2002226061B2 (en) * | 2001-01-18 | 2007-08-02 | The Board Of Trustees Of The Leland Stanford Junior University | Peptides for activation and inhibition of delta PKC |
| US7507711B2 (en) | 2002-04-22 | 2009-03-24 | The Board Of Trustees Of The Leland Stanford Junior University | Peptide inhibitors of protein kinase C |
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