AU2003215869B2 - Hybrid and single chain meganucleases and use thereof - Google Patents

Hybrid and single chain meganucleases and use thereof Download PDF

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Publication number
AU2003215869B2
AU2003215869B2 AU2003215869A AU2003215869A AU2003215869B2 AU 2003215869 B2 AU2003215869 B2 AU 2003215869B2 AU 2003215869 A AU2003215869 A AU 2003215869A AU 2003215869 A AU2003215869 A AU 2003215869A AU 2003215869 B2 AU2003215869 B2 AU 2003215869B2
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Prior art keywords
meganuclease
domain
hybrid
dodecapeptide
derived
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AU2003215869A1 (en
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Sylvain Arnould
Patrick Chames
Andre Choulika
Jean-Charles Epinat
Emmanuel Lacroix
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Cellectis SA
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Cellectis SA
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/16—Hydrolases (3) acting on ester bonds (3.1)
    • C12N9/22—Ribonucleases [RNase]; Deoxyribonucleases [DNase]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Microbiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Oncology (AREA)
  • Virology (AREA)
  • Communicable Diseases (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Detergent Compositions (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
AU2003215869A 2002-03-15 2003-03-14 Hybrid and single chain meganucleases and use thereof Expired AU2003215869B2 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US36411302P 2002-03-15 2002-03-15
US60/364,113 2002-03-15
PCT/IB2003/001352 WO2003078619A1 (en) 2002-03-15 2003-03-14 Hybrid and single chain meganucleases and use thereof

Publications (2)

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AU2003215869A1 AU2003215869A1 (en) 2003-09-29
AU2003215869B2 true AU2003215869B2 (en) 2008-04-24

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ID=28041871

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AU2003215869A Expired AU2003215869B2 (en) 2002-03-15 2003-03-14 Hybrid and single chain meganucleases and use thereof

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US (2) US20060078552A1 (https=)
EP (1) EP1485475B2 (https=)
JP (3) JP2005520519A (https=)
AT (1) ATE372379T1 (https=)
AU (1) AU2003215869B2 (https=)
CA (1) CA2479153C (https=)
DE (1) DE60316124T3 (https=)
DK (1) DK1485475T3 (https=)
ES (1) ES2292994T3 (https=)
WO (1) WO2003078619A1 (https=)

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* Cited by examiner, † Cited by third party
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CA2479153A1 (en) 2003-09-25
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