AU2002363443B2 - New uses for anti-malarial therapeutic agents - Google Patents

New uses for anti-malarial therapeutic agents Download PDF

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Publication number
AU2002363443B2
AU2002363443B2 AU2002363443A AU2002363443A AU2002363443B2 AU 2002363443 B2 AU2002363443 B2 AU 2002363443B2 AU 2002363443 A AU2002363443 A AU 2002363443A AU 2002363443 A AU2002363443 A AU 2002363443A AU 2002363443 B2 AU2002363443 B2 AU 2002363443B2
Authority
AU
Australia
Prior art keywords
hydrogen
mammal
lower alkyl
malarial
virus
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
AU2002363443A
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English (en)
Other versions
AU2002363443A1 (en
Inventor
Lauren Charous
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
APT Pharmaceuticals LLC
Original Assignee
APT Pharmaceuticals LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by APT Pharmaceuticals LLC filed Critical APT Pharmaceuticals LLC
Publication of AU2002363443A1 publication Critical patent/AU2002363443A1/en
Assigned to APT PHARMACEUTICALS, INC. reassignment APT PHARMACEUTICALS, INC. Request for Assignment Assignors: CHAROUS, LAUREN
Application granted granted Critical
Publication of AU2002363443B2 publication Critical patent/AU2002363443B2/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/4709—Non-condensed quinolines and containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/4706—4-Aminoquinolines; 8-Aminoquinolines, e.g. chloroquine, primaquine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/473—Quinolines; Isoquinolines ortho- or peri-condensed with carbocyclic ring systems, e.g. acridines, phenanthridines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Communicable Diseases (AREA)
  • Ophthalmology & Optometry (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Oncology (AREA)
  • Virology (AREA)
  • Pulmonology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Quinoline Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
AU2002363443A 2001-11-09 2002-11-12 New uses for anti-malarial therapeutic agents Ceased AU2002363443B2 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US34587201P 2001-11-09 2001-11-09
US60/345,872 2001-11-09
PCT/US2002/036309 WO2003039546A1 (en) 2001-11-09 2002-11-12 New uses for anti-malarial therapeutic agents

Publications (2)

Publication Number Publication Date
AU2002363443A1 AU2002363443A1 (en) 2003-07-24
AU2002363443B2 true AU2002363443B2 (en) 2006-02-16

Family

ID=23356861

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2002363443A Ceased AU2002363443B2 (en) 2001-11-09 2002-11-12 New uses for anti-malarial therapeutic agents

Country Status (9)

Country Link
US (1) US20040167162A1 (enExample)
EP (1) EP1450803A4 (enExample)
JP (1) JP2005512998A (enExample)
CN (1) CN1289086C (enExample)
AU (1) AU2002363443B2 (enExample)
CA (1) CA2466338C (enExample)
IL (1) IL161821A0 (enExample)
MX (1) MXPA04004393A (enExample)
WO (1) WO2003039546A1 (enExample)

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US7084157B2 (en) * 2002-05-17 2006-08-01 Rajeev Raut Ophthalmic pharmaceutical compositions and methods for treating ocular inflammation
BR0318214A (pt) * 2003-03-27 2006-03-21 Council Scient Ind Res análogos de 8-aminoquinolina substituìda no anel, composição anti-malárica, processo para a preparação de análogos de 8-aminoquinolina substituìda no anel, e, uso de análogos de 8-aminoquinolina substituìda no anel
US20070134596A1 (en) * 2005-12-08 2007-06-14 Adrian Lungu Photosensitive printing element having nanoparticles and method for preparing the printing element
CN101466380A (zh) * 2006-02-16 2009-06-24 麦克莱恩医院 治疗帕金森病的方法和组合物
KR101067443B1 (ko) * 2009-06-23 2011-09-27 여오영 하이드록시클로로퀸을 함유하는 치핵 치료를 위한 국소투여용 주사제 조성물
CN103027915A (zh) * 2011-09-29 2013-04-10 中国医学科学院基础医学研究所 氯喹治疗和氯丙嗪预防肺感染和损伤的用途
CN103705516B (zh) * 2013-12-11 2016-01-06 武汉威立得生物医药有限公司 氯喔星在制备治疗或预防流感病毒感染的药物中的应用
KR101828553B1 (ko) * 2016-04-15 2018-02-13 한국화학연구원 신규한 벤조싸이오펜 유도체, 이의 약학적으로 허용 가능한 염 또는 이의 광학 이성질체, 이의 제조방법 및 이를 유효성분으로 함유하는 바이러스성 질환의 예방 또는 치료용 약학적 조성물
JP2019527207A (ja) * 2016-06-28 2019-09-26 アシスタンス ピュブリーク−オピト ド パリＡｓｓｉｓｔａｎｃｅ Ｐｕｂｌｉｑｕｅ−Ｈｏｐｉｔａｕｘ Ｄｅ Ｐａｒｉｓ ガンマヘルペスウイルスに関連した障害の予防および／または処置での使用のためのヒカントン誘導体およびプリマキン誘導体
CN111658648A (zh) * 2020-02-03 2020-09-15 中国人民解放军军事科学院军事医学研究院 4-氨基喹啉类化合物在治疗冠状病毒感染方面的应用
US20210244705A1 (en) * 2020-02-07 2021-08-12 Centre For Digestive Diseases Therapeutic compositions, products of manufacture and methods for ameliorating or preventing coronavirus infection
CN114908061B (zh) * 2020-02-16 2023-10-27 北京化工大学 穿山甲冠状病毒xCoV及其应用
US11007187B1 (en) * 2020-03-25 2021-05-18 Therapeutica Borealis Oy Medicine for Covid-19 and treatment
US11638722B2 (en) 2020-03-25 2023-05-02 Therapeutica Borealis Oy C/O Avance Attorneys Ltd. Medicine for Covid-19 and treatment
WO2021191496A1 (en) * 2020-03-25 2021-09-30 Therapeutica Borealis Oy Medicine for covid-19 and treatment
US11278602B2 (en) 2020-03-25 2022-03-22 Therapeutica Borealis Oy Medicine for Covid-19 and treatment
WO2021204717A1 (en) * 2020-04-06 2021-10-14 Oxandia Ltd Aminoquinolines for treating coronavirus infections
EP3892275A1 (en) * 2020-04-08 2021-10-13 INSERM (Institut National de la Santé et de la Recherche Médicale) Aerosolization of hcq or its metabolites for the treatment of lung infections
US20230123388A1 (en) * 2020-04-14 2023-04-20 Glanis Pharmaceuticals, Inc. Transdermal and/or topical delivery system comprising hydroxychloroquine and/or chloroquine
CN116033903A (zh) * 2020-04-21 2023-04-28 诺姆·科恩 奎宁及其产生先天免疫应答的用途
AU2021261049A1 (en) * 2020-04-24 2022-11-10 Topelia Aust Limited Products of manufacture and methods for treating, ameliorating or preventing microbial infections
WO2021219244A1 (en) * 2020-04-27 2021-11-04 Immunologik Gmbh 6'-methoxycinchonan-9-ols for the treatment of coronaviral infections
CN115515935B (zh) * 2020-04-30 2025-01-07 中美华世通生物医药科技(武汉)股份有限公司 冠状病毒感染的治疗或预防
IL301183A (en) * 2020-09-14 2023-05-01 Philip Morris Products Sa Pharmaceutical composition comprising hydroxychloroquine and uses thereof
DE102021000717A1 (de) * 2021-02-12 2022-08-18 Forschungszentrum Jülich GmbH Quinacrin als lnhibitor viraler Cysteinproteasen und/oder Serinproteasen
US20240391876A1 (en) * 2021-08-19 2024-11-28 Arizona Board Of Regents On Behalf Of The University Of Arizona Quinacrine and derivatives thereof for treatment of viral infections
CN115869311A (zh) * 2022-12-30 2023-03-31 湖北工业大学 MefloquineHydrochloride在制备抗腺病毒ADV7药物中的应用

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US4181725A (en) * 1977-05-02 1980-01-01 The Regents Of The University Of Michigan Method for alleviating psoriasis
US4496549A (en) * 1983-01-17 1985-01-29 American Cyanamid Company Treatment of malaria with antibiotics
US5153202A (en) * 1988-06-30 1992-10-06 Davis Michael H Method of inhibiting the activity of human immuno deficiency virus (HIV) in vivo
US5376359A (en) * 1992-07-07 1994-12-27 Glaxo, Inc. Method of stabilizing aerosol formulations
US5827681A (en) * 1996-12-20 1998-10-27 University Technology Corporation Rapid detection and drug sensitivity of malaria
WO2000066107A2 (en) * 1999-04-30 2000-11-09 Apt Pharmaceuticals, L.L.C. Antimalarian agents for the treatment of asthma

Also Published As

Publication number Publication date
US20040167162A1 (en) 2004-08-26
IL161821A0 (en) 2005-11-20
CA2466338A1 (en) 2003-05-15
HK1075619A1 (en) 2005-12-23
EP1450803A1 (en) 2004-09-01
JP2005512998A (ja) 2005-05-12
CN1289086C (zh) 2006-12-13
CN1612735A (zh) 2005-05-04
MXPA04004393A (es) 2005-09-12
CA2466338C (en) 2010-01-12
EP1450803A4 (en) 2008-09-03
WO2003039546A1 (en) 2003-05-15

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Legal Events

Date Code Title Description
PC1 Assignment before grant (sect. 113)

Owner name: APT PHARMACEUTICALS, INC.

Free format text: FORMER APPLICANT(S): CHAROUS, LAUREN

FGA Letters patent sealed or granted (standard patent)
MK14 Patent ceased section 143(a) (annual fees not paid) or expired