AU2002333241B2 - Glycoprotein VI fusion proteins - Google Patents
Glycoprotein VI fusion proteins Download PDFInfo
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- AU2002333241B2 AU2002333241B2 AU2002333241A AU2002333241A AU2002333241B2 AU 2002333241 B2 AU2002333241 B2 AU 2002333241B2 AU 2002333241 A AU2002333241 A AU 2002333241A AU 2002333241 A AU2002333241 A AU 2002333241A AU 2002333241 B2 AU2002333241 B2 AU 2002333241B2
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- Prior art keywords
- fusion protein
- collagen
- gpvi
- pro
- ser
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Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/70503—Immunoglobulin superfamily
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/30—Non-immunoglobulin-derived peptide or protein having an immunoglobulin constant or Fc region, or a fragment thereof, attached thereto
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Biophysics (AREA)
- Diabetes (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Hematology (AREA)
- Cell Biology (AREA)
- Toxicology (AREA)
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- Biochemistry (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicinal Preparation (AREA)
- Materials For Medical Uses (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP01116717 | 2001-07-18 | ||
| EP01116717.8 | 2001-07-18 | ||
| PCT/EP2002/007796 WO2003008454A2 (en) | 2001-07-18 | 2002-07-12 | Glycoprotein vi fusion proteins |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| AU2002333241A1 AU2002333241A1 (en) | 2003-05-22 |
| AU2002333241B2 true AU2002333241B2 (en) | 2008-09-18 |
Family
ID=8177994
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU2002333241A Ceased AU2002333241B2 (en) | 2001-07-18 | 2002-07-12 | Glycoprotein VI fusion proteins |
Country Status (6)
| Country | Link |
|---|---|
| US (3) | US7507412B2 (enExample) |
| EP (1) | EP1406929A2 (enExample) |
| JP (1) | JP2005511005A (enExample) |
| AU (1) | AU2002333241B2 (enExample) |
| CA (1) | CA2453986A1 (enExample) |
| WO (1) | WO2003008454A2 (enExample) |
Families Citing this family (27)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MXPA01011274A (es) | 1999-05-07 | 2002-05-06 | Merck Patent Gmbh | Glicoproteina vi recombinante del receptor de colageno sobre plaquetas y su uso farmaceutico. |
| US20070071744A1 (en) * | 2002-06-07 | 2007-03-29 | Gotz Munch | Agents which bind to epitopes of glycoprotein VI |
| US20090130021A1 (en) * | 2002-06-07 | 2009-05-21 | Gotz Munch | Methods, products and uses involving platelets and/or the vasculature |
| US7531178B2 (en) * | 2002-06-07 | 2009-05-12 | Trigen Gmbh | Immunoadhesin comprising a glycoprotein VI domain |
| EP1369128A1 (en) * | 2002-06-07 | 2003-12-10 | Procorde GmbH | Inhibitors of glycoprotein VI and their therapeutic use |
| EP1824979A2 (en) * | 2004-12-10 | 2007-08-29 | Trigen GmbH | Methods, products and uses involving platelets and/or the vasculature |
| EP1876240B1 (en) * | 2005-04-28 | 2012-08-22 | Mochida Pharmaceutical Co., Ltd. | Anti-human platelet membrane glycoprotein vi monoclonal antibody |
| US20090041783A1 (en) | 2005-04-28 | 2009-02-12 | Mochida Pharmaceutical Co., Ltd. | Anti-platelet membrane glycoprotein vi monoclonal antibody |
| SI1873166T1 (sl) | 2006-06-30 | 2011-01-31 | Conaris Res Inst Ag | IZBOLJĹ ANI sgp 130Fc DIMERJI |
| CL2007002567A1 (es) | 2006-09-08 | 2008-02-01 | Amgen Inc | Proteinas aisladas de enlace a activina a humana. |
| EP1916259A1 (en) | 2006-10-26 | 2008-04-30 | Institut National De La Sante Et De La Recherche Medicale (Inserm) | Anti-glycoprotein VI SCFV fragment for treatment of thrombosis |
| US8278271B2 (en) * | 2006-12-13 | 2012-10-02 | University Of Massachusetts | Inhibiting collagen-induced platelet aggregation and activation with peptide variants |
| US10113156B2 (en) | 2009-03-04 | 2018-10-30 | Board Of Regents, The University Of Texas System | Stabilized reverse transcriptase fusion proteins |
| US9150897B2 (en) * | 2010-08-06 | 2015-10-06 | The Regents Of The University Of California | Expression and purification of fusion protein with multiple MBP tags |
| AU2012364736A1 (en) | 2011-12-19 | 2014-07-24 | Amgen Inc. | Variant activin receptor polypeptides, alone or in combination with chemotherapy, and uses thereof |
| HK1218553A1 (zh) | 2013-02-01 | 2017-02-24 | Santa Maria Biotherapeutics, Inc. | 抗激活素a化合物对受试者的施用 |
| US20140220033A1 (en) * | 2013-02-01 | 2014-08-07 | Santa Maria Biotherapeutics, Inc. | Administration of an Anti-Activin-A Compound to a Subject |
| PL3226888T3 (pl) | 2014-12-01 | 2021-11-02 | Ferring B.V. | Podawanie selektywnego transsygnałowego inhibitora IL-6 |
| DK3227325T3 (da) | 2014-12-01 | 2024-07-08 | Ferring Bv | Sammensætninger med selektive hæmmere af il-6-trans-signalering |
| MX2018001465A (es) | 2015-08-05 | 2019-01-31 | Acticor Biotech | Nuevos anticuerpos anti-gpvi humana y sus usos. |
| SG11201906530TA (en) | 2017-02-03 | 2019-08-27 | Acticor Biotech | Inhibition of platelet aggregation using anti-human gpvi antibodies |
| CN109836501A (zh) * | 2017-11-25 | 2019-06-04 | 深圳宾德生物技术有限公司 | 一种靶向her2的单链抗体、嵌合抗原受体t细胞及其制备方法和应用 |
| CN109837304A (zh) * | 2017-11-25 | 2019-06-04 | 深圳宾德生物技术有限公司 | 一种敲除pd1的靶向her2的嵌合抗原受体t细胞及其制备方法和应用 |
| CN109837246A (zh) * | 2017-11-25 | 2019-06-04 | 深圳宾德生物技术有限公司 | 一种敲除pd1的靶向ror1的嵌合抗原受体t细胞及其制备方法和应用 |
| EP4182338A1 (en) * | 2020-07-17 | 2023-05-24 | Instil Bio (Uk) Limited | Receptors providing targeted costimulation for adoptive cell therapy |
| CN111875697B (zh) * | 2020-08-03 | 2021-10-01 | 杭州皓阳生物技术有限公司 | 一种包含肽标签的融合蛋白 |
| EP4355340A4 (en) * | 2021-06-16 | 2025-05-21 | Instil Bio, Inc. | RECEPTORS FOR TARGETED COSTIMULATION FOR ADOPTIVE CELL THERAPY |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2000068377A1 (en) * | 1999-05-07 | 2000-11-16 | Merck Patent Gmbh | Recombinant platelet collagen receptor glycoprotein vi and its pharmaceutical use |
| WO2001000810A1 (en) * | 1999-06-30 | 2001-01-04 | Millennium Pharmaceuticals, Inc. | Glycoprotein vi and uses thereof |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5773574A (en) * | 1990-12-03 | 1998-06-30 | The Scripps Research Institute | Polypeptides for promoting cell attachment |
| US5525491A (en) * | 1991-02-27 | 1996-06-11 | Creative Biomolecules, Inc. | Serine-rich peptide linkers |
| ATE267215T1 (de) * | 1997-12-08 | 2004-06-15 | Lexigen Pharm Corp | Heterodimäre fusionsproteine zur verwendung für gezielte immuntherapie und allgemeine immunerregung |
| CA2367457C (en) * | 1999-03-18 | 2010-09-21 | Merck Patent Gesellschaft Mit Beschraenkter Haftung | Protein for blocking platelet adhesion |
| US6245527B1 (en) * | 1999-06-30 | 2001-06-12 | Millennium Pharmaceuticals, Inc. | Nucleic acid molecules encoding glycoprotein VI and recombinant uses thereof |
| US20030144187A1 (en) * | 1999-09-03 | 2003-07-31 | Colin R. Dunstan | Opg fusion protein compositions and methods |
| DE10018860A1 (de) * | 2000-04-14 | 2001-10-18 | Patent Treuhand Ges Fuer Elektrische Gluehlampen Mbh | Stabilisierung des Betriebs von Gasentladungslampen |
-
2002
- 2002-07-12 EP EP02787127A patent/EP1406929A2/en not_active Withdrawn
- 2002-07-12 AU AU2002333241A patent/AU2002333241B2/en not_active Ceased
- 2002-07-12 WO PCT/EP2002/007796 patent/WO2003008454A2/en not_active Ceased
- 2002-07-12 JP JP2003514012A patent/JP2005511005A/ja active Pending
- 2002-07-12 CA CA002453986A patent/CA2453986A1/en not_active Abandoned
- 2002-07-12 US US10/483,810 patent/US7507412B2/en not_active Expired - Fee Related
-
2007
- 2007-11-27 US US11/987,079 patent/US20080206247A1/en not_active Abandoned
-
2008
- 2008-10-02 US US12/244,339 patent/US20090155897A1/en not_active Abandoned
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2000068377A1 (en) * | 1999-05-07 | 2000-11-16 | Merck Patent Gmbh | Recombinant platelet collagen receptor glycoprotein vi and its pharmaceutical use |
| WO2001000810A1 (en) * | 1999-06-30 | 2001-01-04 | Millennium Pharmaceuticals, Inc. | Glycoprotein vi and uses thereof |
Also Published As
| Publication number | Publication date |
|---|---|
| JP2005511005A (ja) | 2005-04-28 |
| US20090155897A1 (en) | 2009-06-18 |
| WO2003008454A2 (en) | 2003-01-30 |
| US20080206247A1 (en) | 2008-08-28 |
| US20040157300A1 (en) | 2004-08-12 |
| US7507412B2 (en) | 2009-03-24 |
| EP1406929A2 (en) | 2004-04-14 |
| CA2453986A1 (en) | 2003-01-30 |
| WO2003008454A3 (en) | 2003-09-25 |
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| FGA | Letters patent sealed or granted (standard patent) | ||
| MK14 | Patent ceased section 143(a) (annual fees not paid) or expired |