AU2002220132B2 - Nucleic acid amplification methods - Google Patents
Nucleic acid amplification methods Download PDFInfo
- Publication number
- AU2002220132B2 AU2002220132B2 AU2002220132A AU2002220132A AU2002220132B2 AU 2002220132 B2 AU2002220132 B2 AU 2002220132B2 AU 2002220132 A AU2002220132 A AU 2002220132A AU 2002220132 A AU2002220132 A AU 2002220132A AU 2002220132 B2 AU2002220132 B2 AU 2002220132B2
- Authority
- AU
- Australia
- Prior art keywords
- probe
- amplification
- pcr
- sequence
- probes
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Ceased
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6816—Hybridisation assays characterised by the detection means
- C12Q1/682—Signal amplification
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P19/00—Preparation of compounds containing saccharide radicals
- C12P19/26—Preparation of nitrogen-containing carbohydrates
- C12P19/28—N-glycosides
- C12P19/30—Nucleotides
- C12P19/34—Polynucleotides, e.g. nucleic acids, oligoribonucleotides
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6834—Enzymatic or biochemical coupling of nucleic acids to a solid phase
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6844—Nucleic acid amplification reactions
- C12Q1/6862—Ligase chain reaction [LCR]
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/14—Heterocyclic carbon compound [i.e., O, S, N, Se, Te, as only ring hetero atom]
- Y10T436/142222—Hetero-O [e.g., ascorbic acid, etc.]
- Y10T436/143333—Saccharide [e.g., DNA, etc.]
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Engineering & Computer Science (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Microbiology (AREA)
- Genetics & Genomics (AREA)
- General Health & Medical Sciences (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biochemistry (AREA)
- Analytical Chemistry (AREA)
- Biophysics (AREA)
- Immunology (AREA)
- Physics & Mathematics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US09/728,265 US6593086B2 (en) | 1996-05-20 | 2000-12-01 | Nucleic acid amplification methods |
| US09/728,265 | 2000-12-01 | ||
| PCT/US2001/045822 WO2002044339A2 (en) | 2000-12-01 | 2001-12-03 | Nucleic acid amplification methods |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| AU2002220132A2 AU2002220132A2 (en) | 2002-06-11 |
| AU2002220132A1 AU2002220132A1 (en) | 2002-08-15 |
| AU2002220132B2 true AU2002220132B2 (en) | 2007-08-16 |
Family
ID=24926117
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU2002220132A Ceased AU2002220132B2 (en) | 2000-12-01 | 2001-12-03 | Nucleic acid amplification methods |
| AU2013202A Pending AU2013202A (en) | 2000-12-01 | 2001-12-03 | Nucleic acid amplification methods |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU2013202A Pending AU2013202A (en) | 2000-12-01 | 2001-12-03 | Nucleic acid amplification methods |
Country Status (6)
| Country | Link |
|---|---|
| US (2) | US6593086B2 (enExample) |
| EP (1) | EP1343916A4 (enExample) |
| JP (1) | JP2005508599A (enExample) |
| AU (2) | AU2002220132B2 (enExample) |
| CA (1) | CA2430373A1 (enExample) |
| WO (1) | WO2002044339A2 (enExample) |
Families Citing this family (48)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20040018491A1 (en) * | 2000-10-26 | 2004-01-29 | Kevin Gunderson | Detection of nucleic acid reactions on bead arrays |
| US20030175828A1 (en) * | 2002-03-15 | 2003-09-18 | Lazar James G. | Signal amplification by Hybrid Capture |
| US20030236205A1 (en) * | 2002-06-21 | 2003-12-25 | Zhang David Y. | Hybridization signal amplification method (HSAM) nanostructures for diagnostic and therapeutic uses |
| US20050118616A1 (en) * | 2002-08-16 | 2005-06-02 | Kawashima Tadashi R. | Amplification of target nucleotide sequence without polymerase chain reaction |
| GB0230238D0 (en) * | 2002-12-28 | 2003-02-05 | Fu Guoliang | Combined exponential and linear amplification |
| EP1583840A4 (en) * | 2002-12-23 | 2009-03-18 | Epict Technologies | TARGET-RELATED TRANSCRIPTION |
| WO2004106547A2 (en) * | 2003-06-02 | 2004-12-09 | Check-Points Bv | Fast method for detecting micro-organisms in food samples |
| WO2005054466A2 (en) † | 2003-07-25 | 2005-06-16 | Ambion, Inc. | Methods and compositions for preparing rna from a fixed sample |
| US20050112591A1 (en) * | 2003-11-25 | 2005-05-26 | Applera Corporation | Novel method for isolating single stranded product |
| US7566532B1 (en) | 2004-07-02 | 2009-07-28 | Quest Diagnostics Investments Incorporated | Methods for detecting retroviruses |
| US7309589B2 (en) | 2004-08-20 | 2007-12-18 | Vironix Llc | Sensitive detection of bacteria by improved nested polymerase chain reaction targeting the 16S ribosomal RNA gene and identification of bacterial species by amplicon sequencing |
| US20100063263A1 (en) * | 2005-06-23 | 2010-03-11 | Siemens Medical Solutions Diagnostics Gmbh | Magnetic particles with a closed ultrathin silica layer, method for the production thereof and their use |
| US20090137415A1 (en) * | 2005-08-05 | 2009-05-28 | Euclid Diagnostics Llc | SUBTRACTIVE SEPARATION AND AMPLIFICATION OF NON-RIBOSOMAL TRANSCRIBED RNA (nrRNA) |
| WO2007092538A2 (en) | 2006-02-07 | 2007-08-16 | President And Fellows Of Harvard College | Methods for making nucleotide probes for sequencing and synthesis |
| AU2007267517B2 (en) * | 2006-05-24 | 2012-12-20 | Gen-Probe Incorporated | Probes and kits for determining the presence of mycobacterium tuberculosis complex organisms in a test sample and method of amplifying gram-positive bacteria and fungi employing capture probe |
| US8084206B2 (en) * | 2006-08-30 | 2011-12-27 | Arizona Board of Regents, a body corporate acting for and on behalf of Arizona State University | High speed, high fidelity, high sensitivity nucleic acid detection |
| WO2008026719A1 (en) | 2006-08-31 | 2008-03-06 | Toyo Seikan Kaisha, Ltd. | Nucleic acid amplification method |
| US20080090238A1 (en) * | 2006-10-12 | 2008-04-17 | Dan-Hui Dorothy Yang | Increased sensitivity of proximity ligation assays |
| US20100047792A1 (en) * | 2007-04-10 | 2010-02-25 | Szendroe Istvan | Label-free optical detection method |
| US20090181389A1 (en) * | 2008-01-11 | 2009-07-16 | Signosis, Inc., A California Corporation | Quantitative measurement of nucleic acid via ligation-based linear amplification |
| US20100151473A1 (en) * | 2008-12-10 | 2010-06-17 | Yeakley Joanne M | Methods and compositions for hybridizing nucleic acids |
| EP2744916A4 (en) | 2011-07-13 | 2015-06-17 | Primeradx Inc | MULTIMODAL PROCEDURE FOR THE SIMULTANEOUS DETECTION AND QUANTIFICATION OF MULTIPLE NUCLEIC ACIDS IN ONE SAMPLE |
| EP2785865A1 (en) * | 2011-12-02 | 2014-10-08 | Qiagen GmbH | Method and kit for characterizing rna in a composition |
| EP2653559A1 (en) * | 2012-04-20 | 2013-10-23 | Samsung Electronics Co., Ltd | Polynucleotide and use thereof |
| WO2014071070A1 (en) | 2012-11-01 | 2014-05-08 | Pacific Biosciences Of California, Inc. | Compositions and methods for selection of nucleic acids |
| KR20150029432A (ko) * | 2013-09-10 | 2015-03-18 | 삼성전자주식회사 | 핵산 검출 방법 |
| US11859246B2 (en) | 2013-12-11 | 2024-01-02 | Accuragen Holdings Limited | Methods and compositions for enrichment of amplification products |
| US11286519B2 (en) | 2013-12-11 | 2022-03-29 | Accuragen Holdings Limited | Methods and compositions for enrichment of amplification products |
| EP3495506B1 (en) | 2013-12-11 | 2023-07-12 | AccuraGen Holdings Limited | Methods for detecting rare sequence variants |
| US11987836B2 (en) | 2014-09-30 | 2024-05-21 | Global Life Sciences Solutions Usa Llc | Method for nucleic acid analysis directly from an unpurified biological sample |
| US10793922B2 (en) * | 2014-10-20 | 2020-10-06 | Envirologix Inc. | Compositions and methods for detecting an RNA virus |
| EP3209251A4 (en) * | 2014-10-22 | 2018-03-28 | International Partnership for Microbicides, Inc. | Platinum-catalyzed silicone drug delivery devices and methods of use thereof |
| CN105803055A (zh) * | 2014-12-31 | 2016-07-27 | 天昊生物医药科技(苏州)有限公司 | 一种基于多重循环延伸连接的靶基因区域富集新方法 |
| HK1259101A1 (zh) | 2015-10-09 | 2019-11-22 | Accuragen Holdings Limited | 用於富集扩增产物的方法及组合物 |
| US12163184B2 (en) | 2015-12-03 | 2024-12-10 | Accuragen Holdings Limited | Methods and compositions for forming ligation products |
| WO2017201102A1 (en) | 2016-05-16 | 2017-11-23 | Accuragen Holdings Limited | Method of improved sequencing by strand identification |
| WO2018035170A1 (en) | 2016-08-15 | 2018-02-22 | Accuragen Holdings Limited | Compositions and methods for detecting rare sequence variants |
| US10626473B2 (en) * | 2016-10-03 | 2020-04-21 | Genetics & IVG Institute, Inc. | Methods and compositions for detecting Zika virus |
| CN111511925B (zh) * | 2017-11-29 | 2023-11-14 | 帕纳金股份有限公司 | 用于扩增靶核酸的方法及用于扩张靶核酸的组合物 |
| US10859997B1 (en) | 2017-12-04 | 2020-12-08 | Omax Corporation | Numerically controlled machining |
| CN112601823A (zh) | 2018-06-12 | 2021-04-02 | 安可济控股有限公司 | 用于形成连接产物的方法和组合物 |
| GB201812192D0 (en) | 2018-07-26 | 2018-09-12 | Ttp Plc | Variable temperature reactor, heater and control circuit for the same |
| CN112770776B (zh) | 2018-07-30 | 2025-08-19 | 瑞德库尔有限责任公司 | 用于样品处理或分析的方法和系统 |
| WO2020033394A1 (en) * | 2018-08-06 | 2020-02-13 | Northwestern University | Enhanced capture of target nucleic acids |
| US20210164025A1 (en) * | 2018-08-14 | 2021-06-03 | President And Fellows Of Harvard College | In vitro detection of nucleic acid |
| CN110066890A (zh) * | 2019-06-03 | 2019-07-30 | 广西大学 | 一种快速检测ibv二温式纳米pcr试剂盒及应用 |
| WO2021119202A1 (en) * | 2019-12-10 | 2021-06-17 | Enumerix, Inc. | Compositions and methods of nucleic acid amplification |
| CN113528513B (zh) * | 2021-08-12 | 2022-11-22 | 基因科技(上海)股份有限公司 | 原位杂交探针复合体、其制备方法及应用 |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1998004746A1 (en) * | 1996-07-31 | 1998-02-05 | Mount Sinai School Of Medicine Of The City University Of New York | Nucleic acid amplification method: ramification-extension amplification method (ram) |
| WO1998004745A1 (en) * | 1996-07-31 | 1998-02-05 | Mount Sinai School Of Medicine Of The City University Of New York | Nucleic acid amplification method: hybridization signal amplification method (hsam) |
Family Cites Families (41)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4786600A (en) | 1984-05-25 | 1988-11-22 | The Trustees Of Columbia University In The City Of New York | Autocatalytic replication of recombinant RNA |
| US4957858A (en) | 1986-04-16 | 1990-09-18 | The Salk Instute For Biological Studies | Replicative RNA reporter systems |
| US5118605A (en) | 1984-10-16 | 1992-06-02 | Chiron Corporation | Polynucleotide determination with selectable cleavage sites |
| US4883750A (en) | 1984-12-13 | 1989-11-28 | Applied Biosystems, Inc. | Detection of specific sequences in nucleic acids |
| US4925785A (en) | 1986-03-07 | 1990-05-15 | Biotechnica Diagnostics, Inc. | Nucleic acid hybridization assays |
| US4980456A (en) * | 1987-04-06 | 1990-12-25 | Scripps Clinic And Research Foundation | Recombinant factor VIIIC derived fragments |
| US5449602A (en) | 1988-01-13 | 1995-09-12 | Amoco Corporation | Template-directed photoligation |
| EP0359789B1 (en) | 1988-01-21 | 1993-08-04 | Genentech, Inc. | Amplification and detection of nucleic acid sequences |
| US4988617A (en) | 1988-03-25 | 1991-01-29 | California Institute Of Technology | Method of detecting a nucleotide change in nucleic acids |
| EP0426756A4 (en) | 1988-07-26 | 1991-11-21 | Genelabs Incorporated | Rna and dna amplification techniques |
| US5185243A (en) | 1988-08-25 | 1993-02-09 | Syntex (U.S.A.) Inc. | Method for detection of specific nucleic acid sequences |
| US5118801A (en) | 1988-09-30 | 1992-06-02 | The Public Health Research Institute | Nucleic acid process containing improved molecular switch |
| US5112734A (en) | 1989-05-26 | 1992-05-12 | Gene-Trak Systems | Target-dependent synthesis of an artificial gene for the synthesis of a replicatable rna |
| US5200314A (en) | 1990-03-23 | 1993-04-06 | Chiron Corporation | Polynucleotide capture assay employing in vitro amplification |
| CA2046713A1 (en) | 1990-10-16 | 1992-04-17 | Richard M. Martinelli | Amplification of midivariant dna templates |
| CA2076750C (en) | 1990-12-31 | 2003-07-08 | Promega Corporation | Nucleic acid amplification with dna-dependent rna polymerase activity of rna replicases |
| JP3080178B2 (ja) | 1991-02-18 | 2000-08-21 | 東洋紡績株式会社 | 核酸配列の増幅方法およびそのための試薬キット |
| JP3085409B2 (ja) | 1991-03-29 | 2000-09-11 | 東洋紡績株式会社 | 標的核酸配列の検出方法およびそのための試薬キット |
| DE4214112A1 (de) * | 1991-08-02 | 1993-02-04 | Europ Lab Molekularbiolog | Neues verfahren zur sequenzierung von nukleinsaeuren |
| DE69233630T2 (de) | 1991-12-23 | 2007-05-31 | Chiron Corp., Emeryville | Sätze von HIV-Sonden zur Verwendung in Sandwich-Hydridisierungsassays in Lösungsphase |
| US5834202A (en) | 1992-08-04 | 1998-11-10 | Replicon, Inc. | Methods for the isothermal amplification of nucleic acid molecules |
| US6261808B1 (en) | 1992-08-04 | 2001-07-17 | Replicon, Inc. | Amplification of nucleic acid molecules via circular replicons |
| WO1994003624A1 (en) | 1992-08-04 | 1994-02-17 | Auerbach Jeffrey I | Methods for the isothermal amplification of nucleic acid molecules |
| CA2155186A1 (en) * | 1993-02-01 | 1994-08-18 | Kevin M. Ulmer | Methods and apparatus for dna sequencing |
| US5422252A (en) | 1993-06-04 | 1995-06-06 | Becton, Dickinson And Company | Simultaneous amplification of multiple targets |
| US5601978A (en) | 1993-09-03 | 1997-02-11 | Abbott Laboratories | Oligonucleotides and methods for the detection of chlamydia trachomatis |
| NL9301957A (nl) | 1993-11-11 | 1995-06-01 | U Gene Research Bv | Werkwijze voor het identificeren van micro-organismen, en daarvoor bruikbare hulpmiddelen. |
| US5523204A (en) | 1993-12-10 | 1996-06-04 | Becton Dickinson And Company | Detection of nucleic acids in cells by strand displacement amplification |
| SE9400522D0 (sv) | 1994-02-16 | 1994-02-16 | Ulf Landegren | Method and reagent for detecting specific nucleotide sequences |
| WO1995035390A1 (en) | 1994-06-22 | 1995-12-28 | Mount Sinai School Of Medicine Of The City University Of New York | Ligation-dependent amplification for the detection of infectious pathogens and abnormal genes |
| US5773268A (en) * | 1994-11-09 | 1998-06-30 | Cedars-Sinai Medical Center | Chromosome 21 gene marker, compositions and methods using same |
| US5616465A (en) | 1995-08-09 | 1997-04-01 | The Regents Of The University Of California | Detection and isolation of nucleic acid sequences using competitive hybridization probes |
| US5854033A (en) | 1995-11-21 | 1998-12-29 | Yale University | Rolling circle replication reporter systems |
| JP3974941B2 (ja) | 1995-11-21 | 2007-09-12 | イェール ユニバーシティ | 単分子セグメントの増幅および検出 |
| US6162965A (en) * | 1997-06-02 | 2000-12-19 | Novartis Ag | Plant transformation methods |
| US6124120A (en) | 1997-10-08 | 2000-09-26 | Yale University | Multiple displacement amplification |
| WO2000004193A1 (en) | 1998-07-20 | 2000-01-27 | Yale University | Method for detecting nucleic acids using target-mediated ligation of bipartite primers |
| WO2000015849A1 (en) | 1998-09-15 | 2000-03-23 | Yale University | Artificial long terminal repeat vectors |
| CA2342838A1 (en) | 1998-09-15 | 2000-03-23 | Yale University | Molecular cloning using rolling circle amplification |
| AU778438B2 (en) | 1999-04-06 | 2004-12-02 | Yale University | Fixed address analysis of sequence tags |
| EP1206577B1 (en) | 1999-08-13 | 2006-03-01 | Yale University | Binary encoded sequence tags |
-
2000
- 2000-12-01 US US09/728,265 patent/US6593086B2/en not_active Expired - Lifetime
-
2001
- 2001-12-03 JP JP2002546688A patent/JP2005508599A/ja active Pending
- 2001-12-03 AU AU2002220132A patent/AU2002220132B2/en not_active Ceased
- 2001-12-03 WO PCT/US2001/045822 patent/WO2002044339A2/en not_active Ceased
- 2001-12-03 EP EP01998621A patent/EP1343916A4/en not_active Ceased
- 2001-12-03 CA CA002430373A patent/CA2430373A1/en not_active Abandoned
- 2001-12-03 AU AU2013202A patent/AU2013202A/xx active Pending
-
2003
- 2003-06-13 US US10/461,848 patent/US8632999B1/en not_active Expired - Lifetime
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5942391A (en) * | 1994-06-22 | 1999-08-24 | Mount Sinai School Of Medicine | Nucleic acid amplification method: ramification-extension amplification method (RAM) |
| WO1998004746A1 (en) * | 1996-07-31 | 1998-02-05 | Mount Sinai School Of Medicine Of The City University Of New York | Nucleic acid amplification method: ramification-extension amplification method (ram) |
| WO1998004745A1 (en) * | 1996-07-31 | 1998-02-05 | Mount Sinai School Of Medicine Of The City University Of New York | Nucleic acid amplification method: hybridization signal amplification method (hsam) |
Non-Patent Citations (4)
| Title |
|---|
| Thomas C. et. al., Arch. Pathol. Lab. Med., 1999, 123, pg 1170 * |
| Wu F. et. al., Abstracts of the General Meeting of the American Chemical Society for Microbiology, 1997, 97, pg 155 * |
| Zhang D. et. al., Abstracts of the General meeting of the American Society for Microbiolgy, 1999, 132(12), pg 203 * |
| Zhang, D. et. al., Gene, 1998, 211(2), pg 277-285 * |
Also Published As
| Publication number | Publication date |
|---|---|
| US20020182598A1 (en) | 2002-12-05 |
| CA2430373A1 (en) | 2002-06-06 |
| US6593086B2 (en) | 2003-07-15 |
| AU2013202A (en) | 2002-06-11 |
| JP2005508599A (ja) | 2005-04-07 |
| AU2002220132A2 (en) | 2002-06-11 |
| WO2002044339A3 (en) | 2003-05-30 |
| EP1343916A2 (en) | 2003-09-17 |
| US8632999B1 (en) | 2014-01-21 |
| EP1343916A4 (en) | 2005-02-09 |
| WO2002044339A2 (en) | 2002-06-06 |
| US20140038238A1 (en) | 2014-02-06 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| AU2002220132B2 (en) | Nucleic acid amplification methods | |
| US6855523B2 (en) | Nucleic acid amplification method: ramification-extension amplification method (RAM) | |
| US5876924A (en) | Nucleic acid amplification method hybridization signal amplification method (HSAM) | |
| US20070269799A9 (en) | Nucleic acid amplification methods | |
| AU2002220132A1 (en) | Nucleic acid amplification methods | |
| WO1998004746A9 (en) | Nucleic acid amplification method: ramification-extension amplification method (ram) | |
| US7361489B2 (en) | Nucleic acid amplification methods | |
| EP0717782A1 (en) | Ligation-dependent amplification for the detection of infectious pathogens and abnormal genes | |
| EP3095873A1 (en) | Methods and compositions for nucleic acid amplification | |
| CN110612354B (zh) | 用于分离靶核酸的组合物和方法 | |
| USRE38442E1 (en) | Nucleic acid amplification method hybridization signal amplification method (HSAM) | |
| AU2152099A (en) | Specific and sensitive nucleic acid detection method | |
| WO2005061722A1 (en) | Nucleic acid amplification methods | |
| AU2002348438A1 (en) | Nucleic acid amplification methods |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| DA3 | Amendments made section 104 |
Free format text: THE NATURE OF THE AMENDMENT IS AS SHOWN IN THE STATEMENT(S) FILED 28 JUL 2003 |
|
| PC1 | Assignment before grant (sect. 113) |
Owner name: HAMILTON THORNE BIOSCIENCES, INC Free format text: FORMER APPLICANT(S): ZHANG, DAVID; BRANDWEIN, MARGARET; HSUIH, TERENCE |
|
| FGA | Letters patent sealed or granted (standard patent) | ||
| MK14 | Patent ceased section 143(a) (annual fees not paid) or expired |